Journal of Clinical Oncology, Vol 1, 270-276, Copyright © 1983 by American Society of Clinical Oncology
Mycosis fungoides: subcutaneous and visceral tumors, orbital involvement, and ophthalmoplegia
EG Whitbeck, AS Spiers and M Hussain
A patient with advanced severe mycosis fungoides presented several unusual
features, including prominent lesions of the palate and tongue and an
orbital tumor with exophthalmos and ophthalmoplegia. A hitherto undescribed
feature was the development of multiple, massive subcutaneous tumors
unrelated to the dermis or to lymph nodes, and large tumors in the
connective tissues of the buttock, flank, and retroperitoneum. The usual
sites of extracutaneous dissemination of mycosis fungoides--lymph nodes,
spleen, liver, lungs, and blood--were not demonstrably involved. This may
be a new pattern of dissemination for this disease. Of practical importance
is the immediate and complete relief of exophthalmos and ophthalmoplegia
that was obtained with emergency radiotherapy.