Journal of Clinical Oncology, Vol 1, 290-294, Copyright © 1983 by American Society of Clinical Oncology
Diagnostic accuracies of clinical studies in patients with small cell carcinoma of the lung
LY Chak, SB Paryani, BI Sikic, P Lockbaum, FM Torti and SK Carter
The diagnostic accuracy of clinical studies done in 38 patients with small
cell carcinoma of the lung was analyzed by comparing the test results to
autopsy findings. The chest radiograph was accurate in 31 of 38 patients
(82%). The accuracy of the chest radiograph was higher in evaluating the
lung parenchyma and mediastinum than in evaluating the hilum and pleura.
Computerized tomographic brain scan was accurate in 11 of 12 patients.
However, all the diagnostic studies used for assessing the liver, including
physical examination, serum liver enzyme and bilirubin measurements, and
radionuclide liver scan, were only moderately accurate. More accurate
studies for detecting liver metastasis in patients with small cell
carcinoma are needed.