Journal of Clinical Oncology, Vol 13, 1249-1254, Copyright © 1995 by American Society of Clinical Oncology
Test/retest study of the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire
MJ Hjermstad, SD Fossa, K Bjordal and S Kaasa
Norwegian Cancer Society/Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo.
PURPOSE: The European Organization for Research and Treatment of Cancer
Core Quality of Life Questionnaire (EORTC QLQ-C30) is a well-validated
instrument that assesses health-related quality of life (HRQOL) in cancer
patients. It is used in cancer clinical trials in Europe, Canada, and the
United States, and has demonstrated high reliability and validity in
different groups of cancer patients. Despite thorough testing of
reliability and validity, we have not identified any reports on its
test/retest reliability; thus, a test/retest study was performed at the
Norwegian Radium Hospital (NRH). MATERIALS AND METHODS: Cancer patients
from the outpatient clinic who were off treatment for > or = 3 months
were eligible for the study. The EORTC QLQ-C30 was given to the patients
when they presented for their visit. The second questionnaire was received
by the patients 4 days later. Of 291 eligible patients, 270 (93%) agreed to
participate and 190 (73%) completed both questionnaires. RESULTS: The
test/retest reliability measured by Pearson's correlation coefficient was
high for all functional scales, with a range from .82 for cognitive and
role function to .91 for physical function. The r value for global HRQOL
was .85. For the symptom scales--nausea/vomiting, fatigue, and pain--the
coefficients were .63, .83, and .86, respectively. The single-item
coefficients ranged from .72 for diarrhea to .84 for financial impact. The
Spearman rank correlation was in the same range for all dimensions.
CONCLUSION: The EORTC QLQ-C30 seems to yield high test/retest reliability
in patients with various cancer diagnoses whose condition is not expected
to change during the time of measurement.
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