EDITORIALS

The Key and the Lamppost

Samuel Hellman

JCO Oct 1 1999: 3007–3008. [Full Text] [PDF]

RAPID PUBLICATIONS
	Clinical and Pharmacokinetic Phase I Study of Multitargeted Antifolate (LY231514) in Combination With Cisplatin
	R. Thödtmann, H. Depenbrock, H. Dumez, J. Blatter, R. D. Johnson, A. van Oosterom, and A.-R. Hanauske
	JCO Oct 1 1999: 3009–3016. [Abstract] [Full Text] [PDF]

BREAST CANCER
	BRCA1/BRCA2 Germline Mutations in Locally Recurrent Breast Cancer Patients After Lumpectomy and Radiation Therapy: Implications for Breast-Conserving Management in Patients With BRCA1/BRCA2 Mutations
	Bruce C. Turner, Elizabeth Harrold, Ellen Matloff, Tanya Smith, Andrew A. Gumbs, Malcom Beinfield, Brian Ward, Mark Skolnick, Peter M. Glazer, Alun Thomas, and Bruce G. Haffty
	JCO Oct 1 1999: 3017–3024. [Abstract] [Full Text] [PDF]
	Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Hematopoietic Growth Factor PIXY321 After Moderate-Dose Fluorouracil, Doxorubicin, and Cyclophosphamide in Stage II and III Breast Cancer
	Stephen E. Jones, Pankaj Khandelwal, Kristi McIntyre, Robert Mennel, Douglas Orr, Robert Kirby, Edward Agura, Lewis Duncan, William Hyman, Tammy Roque, David Regan, Michael Schuster, Nikolay Dimitrov, Leslie Garrison, and Mary Lange
	JCO Oct 1 1999: 3025–3032. [Abstract] [Full Text] [PDF]
	Combination Versus Sequential Doxorubicin and Docetaxel as Primary Chemotherapy for Breast Cancer: A Randomized Pilot Trial of the Hoosier Oncology Group
	Kathy D. Miller, Worta McCaskill-Stevens, Judy Sisk, David M. Loesch, Frank Monaco, Roopa Seshadri, and George W. Sledge, Jr
	JCO Oct 1 1999: 3033–3037. [Abstract] [Full Text] [PDF]
	Randomized Phase II Study of High-Dose Paclitaxel With or Without Amifostine in Patients With Metastatic Breast Cancer
	K. Gelmon, E. Eisenhauer, C. Bryce, A. Tolcher, L. Mayer, E. Tomlinson, B. Zee, M. Blackstein, E. Tomiak, J. Yau, G. Batist, B. Fisher, and J. Iglesias
	JCO Oct 1 1999: 3038–3047. [Abstract] [Full Text] [PDF]
	Dissemination Risk Index Based on Plasminogen Activator System Components in Primary Breast Cancer
	Cécile Bouchet, Kamel Hacène, Pierre-Marie Martin, Véronique Becette, Michèle Tubiana-Hulin, Serge Lasry, Jean Oglobine, and Frédérique Spyratos
	JCO Oct 1 1999: 3048–3057. [Abstract] [Full Text] [PDF]
	Biologic Markers as Predictors of Clinical Outcome From Systemic Therapy for Primary Operable Breast Cancer
	J. Chang, T. J. Powles, D. C. Allred, S. E. Ashley, G. M. Clark, A. Makris, L. Assersohn, R. K. Gregory, C. K. Osborne, and M. Dowsett
	JCO Oct 1 1999: 3058–3063. [Abstract] [Full Text] [PDF]
	Prognostic and Predictive Factors for Patients With Metastatic Breast Cancer Undergoing Aggressive Induction Therapy Followed by High-Dose Chemotherapy With Autologous Stem-Cell Support
	D. A. Rizzieri, J. J. Vredenburgh, R. Jones, M. Ross, E. J. Shpall, A. Hussein, G. Broadwater, D. Berry, W. P. Petros, C. Gilbert, M. L. Affronti, D. Coniglio, P. Rubin, M. Elkordy, G. D. Long, N. J. Chao, and W. P. Peters
	JCO Oct 1 1999: 3064–3074. [Abstract] [Full Text] [PDF]
	Telomerase Activity and Prognosis in Primary Breast Cancers
	Lisa A. Carey, Nam W. Kim, Steven Goodman, Jeffrey Marks, Gregory Henderson, Christopher B. Umbricht, Jeffrey S. Dome, William Dooley, Stefan R. Amshey, and Saraswati Sukumar
	JCO Oct 1 1999: 3075–3081. [Abstract] [Full Text] [PDF]
	Cost-Utility Analysis of Chemotherapy Using Paclitaxel, Docetaxel, or Vinorelbine for Patients With Anthracycline-Resistant Breast Cancer
	P. P. Leung, I. F. Tannock, A. M. Oza, A. Puodziunas, and G. Dranitsaris
	JCO Oct 1 1999: 3082–3090. [Abstract] [Full Text] [PDF]
	Effect of Radiotherapy and Chemotherapy on Pulmonary Function After Treatment for Breast Cancer and Lymphoma: A Follow-Up Study
	Jacqueline C.M. Theuws, Sara H. Muller, Yvette Seppenwoolde, Stefan L.S. Kwa, Liesbeth J. Boersma, Guus A.M. Hart, Paul Baas, and Joos V. Lebesque
	JCO Oct 1 1999: 3091–3100. [Abstract] [Full Text] [PDF]

HEMATOLOGIC MALIGNANCIES
	High-Dose Therapy and Autologous Stem-Cell Transplantation for Adult Patients With Hodgkin's Disease Who Do Not Enter Remission After Induction Chemotherapy: Results in 175 Patients Reported to the European Group for Blood and Marrow Transplantation
	John W. Sweetenham, Angelo M. Carella, Golnaz Taghipour, David Cunningham, Robert Marcus, Aldo Della Volpe, David C. Linch, Norbert Schmitz, and Anthony H. Goldstone
	JCO Oct 1 1999: 3101–3109. [Abstract] [Full Text] [PDF]
	Randomized Trial of a Slow-Release Versus a Standard Formulation of Cytarabine for the Intrathecal Treatment of Lymphomatous Meningitis
	Michael J. Glantz, Suzanne LaFollette, Kurt A. Jaeckle, William Shapiro, Lode Swinnen, Jack R. Rozental, Surasak Phuphanich, Lisa R. Rogers, John C. Gutheil, Tracy Batchelor, David Lyter, Marc Chamberlain, Bernard L. Maria, Charles Schiffer, Rifaat Bashir, David Thomas, Wayne Cowens, and Stephen B. Howell
	JCO Oct 1 1999: 3110–3116. [Abstract] [Full Text] [PDF]
	Pentostatin Therapy of T-Cell Lymphomas With Cutaneous Manifestations
	Razelle Kurzrock, Susan Pilat, and Madeleine Duvic
	JCO Oct 1 1999: 3117–3121. [Abstract] [Full Text] [PDF]
	Increased Incidence of Hodgkin's Disease After Allogeneic Bone Marrow Transplantation
	Philip A. Rowlings, Rochelle E. Curtis, Jakob R. Passweg, H. Joachim Deeg, Gérard Socié, Lois B. Travis, Douglas W. Kingma, Elaine S. Jaffe, Kathleen A. Sobocinski, and Mary M. Horowitz
	JCO Oct 1 1999: 3122–3127. [Abstract] [Full Text] [PDF]
	Outcome in Patients With Myelodysplastic Syndrome After Autologous Bone Marrow Transplantation for Non-Hodgkin's Lymphoma
	Jonathan W. Friedberg, Donna Neuberg, Richard M. Stone, Edwin Alyea, Haddy Jallow, Ann LaCasce, Peter M. Mauch, John G. Gribben, Jerome Ritz, Lee M. Nadler, Robert J. Soiffer, and Arnold S. Freedman
	JCO Oct 1 1999: 3128–3135. [Abstract] [Full Text] [PDF]

GYNECOLOGIC CANCER
	Results of a European Organization for Research and Treatment of Cancer/Early Clinical Studies Group Phase II Trial of First-Line Irinotecan in Patients With Advanced or Recurrent Squamous Cell Carcinoma of the Cervix
	Catherine Lhommé, Pierre Fumoleau, Pierre Fargeot, Yvan Krakowski, Véronique Dieras, Jacques Chauvergne, Philippe Vennin, Paul Rebattu, Henry Roche, Jean-Louis Misset, Marie-Ange Lentz, Martine Van Glabbeke, Anne Matthieu-Boué, Dominique Mignard, and Bernard Chevallier
	JCO Oct 1 1999: 3136–3142. [Abstract] [Full Text] [PDF]

BRAIN TUMORS
	Accelerated Radiotherapy, Carbogen, and Nicotinamide in Glioblastoma Multiforme: Report of European Organization for Research and Treatment of Cancer Trial 22933
	Raymond Miralbell, Françoise Mornex, Richard Greiner, Michel Bolla, Guy Storme, Maarten Hulshof, Jacques Bernier, Juliana Denekamp, Ana M. Rojas, Marianne Pierart, Martine van Glabbeke, and René O. Mirimanoff
	JCO Oct 1 1999: 3143–3149. [Abstract] [Full Text] [PDF]

HEAD AND NECK CANCER
	Clinical Relevance of Expression of the CIP/KIP Cell-Cycle Inhibitors p21 and p27 in Laryngeal Cancer
	Giancarlo Pruneri, Lorenzo Pignataro, Nadia Carboni, Roberto Buffa, Devrim Di Finizio, Bruno Mario Cesana, and Antonino Neri
	JCO Oct 1 1999: 3150–3159. [Abstract] [Full Text] [PDF]

GENITOURINARY CANCER
	Vinblastine Versus Vinblastine Plus Oral Estramustine Phosphate for Patients With Hormone-Refractory Prostate Cancer: A Hoosier Oncology Group and Fox Chase Network Phase III Trial
	Gary Hudes, Lawrence Einhorn, Eric Ross, Andrew Balsham, Patrick Loehrer, Harry Ramsey, John Sprandio, Michael Entmacher, William Dugan, Rafat Ansari, Frank Monaco, Mark Hanna, and Bruce Roth
	JCO Oct 1 1999: 3160–3166. [Abstract] [Full Text] [PDF]
	Declining Rates of Extracapsular Extension After Radical Prostatectomy: Evidence for Continued Stage Migration
	Faiyaaz M. Jhaveri, Eric A. Klein, Patrick A. Kupelian, Craig Zippe, and Howard S. Levin
	JCO Oct 1 1999: 3167–3172. [Abstract] [Full Text] [PDF]
	Long-Term Survival in Metastatic Transitional-Cell Carcinoma and Prognostic Factors Predicting Outcome of Therapy
	Dean F. Bajorin, Paul M. Dodd, Madhu Mazumdar, Melissa Fazzari, John A. McCaffrey, Howard I. Scher, Harry Herr, Geralyn Higgins, and Mary G. Boyle
	JCO Oct 1 1999: 3173–3181. [Abstract] [Full Text] [PDF]
	Predicting Cancer Progression in Patients With Stage T1 Bladder Carcinoma
	Liang Cheng, Roxann M. Neumann, Amy L. Weaver, Bruce E. Spotts, and David G. Bostwick
	JCO Oct 1 1999: 3182–3187. [Abstract] [Full Text] [PDF]

LUNG CANCER
	Mitomycin, Ifosfamide, and Cisplatin in Unresectable Non–Small-Cell Lung Cancer: Effects on Survival and Quality of Life
	M. H. Cullen, L. J. Billingham, C. M. Woodroffe, A. D. Chetiyawardana, N. H. Gower, R. Joshi, D. R. Ferry, R. M. Rudd, S. G. Spiro, J. E. Cook, C. Trask, E. Bessell, C. K. Connolly, J. Tobias, and R. L. Souhami
	JCO Oct 1 1999: 3188–3194. [Abstract] [Full Text] [PDF]
	Phase I/II Study of Vinorelbine, Mitomycin, and Cisplatin for Stage IIIB or IV Non–Small-Cell Lung Cancer
	Kiyoyuki Furuse, Masaaki Kawahara, Yutaka Nishiwaki, Masahiro Fukuoka, Minoru Takada, Mitsunori Miyashita, and Yasuo Ohashi
	JCO Oct 1 1999: 3195–3200. [Abstract] [Full Text] [PDF]
	Prognostic Importance of the Standardized Uptake Value on 18F-Fluoro-2-Deoxy-Glucose–Positron Emission Tomography Scan in Non–Small-Cell Lung Cancer: An Analysis of 125 Cases
	Johan F. Vansteenkiste, Sigrid G. Stroobants, Patrick J. Dupont, Paul R. De Leyn, Erik K. Verbeken, Georges J. Deneffe, Luc A. Mortelmans, and Maurits G. Demedts
	JCO Oct 1 1999: 3201–3206. [Abstract] [Full Text] [PDF]

PEDIATRIC ONCOLOGY
	Cancer and Cardiac Mortality Among 15-Year Survivors of Cancer Diagnosed During Childhood or Adolescence
	Daniel M. Green, Andrew Hyland, Catherine S. Chung, Michael A. Zevon, and Brenda C. Hall
	JCO Oct 1 1999: 3207–3215. [Abstract] [Full Text] [PDF]
	Long-Term Survivors of Advanced Neuroblastoma With MYCN Amplification: A Report of 19 Patients Surviving Disease-Free for More Than 66 Months
	K. Kawa, N. Ohnuma, M. Kaneko, K. Yamamoto, T. Etoh, H. Mugishima, M. Ohhira, J. Yokoyama, F. Bessho, T. Honna, J. Yoshizawa, K. Nakada, M. Iwafuchi, T. Nozaki, J. Mimaya, T. Sawada, T. Nakamura, H. Miyata, K. Yamato, and Y. Tsuchida
	JCO Oct 1 1999: 3216–3220. [Abstract] [Full Text] [PDF]
	Oral Etoposide for Refractory and Relapsed Neuroblastoma
	Brian H. Kushner, Kim Kramer, and Nai-Kong V. Cheung
	JCO Oct 1 1999: 3221–3225. [Abstract] [Full Text] [PDF]
	Acute Myelogenous Leukemia After Treatment for Malignant Germ Cell Tumors in Children
	Dominik T. Schneider, Elisabeth Hilgenfeld, Dirk Schwabe, Wolfgang Behnisch, Andreas Zoubek, Rüdiger Wessalowski, and Ulrich Göbel
	JCO Oct 1 1999: 3226–3233. [Abstract] [Full Text] [PDF]
	Comparison of CSF Cytology and Spinal Magnetic Resonance Imaging in the Detection of Leptomeningeal Disease in Pediatric Medulloblastoma or Primitive Neuroectodermal Tumor
	Maryam Fouladi, Amar Gajjar, James M. Boyett, Andrew W. Walter, Stephen J. Thompson, Thomas E. Merchant, Jesse J. Jenkins, James W. Langston, Aiyi Liu, Larry E. Kun, and Richard L. Heideman
	JCO Oct 1 1999: 3234–3237. [Abstract] [Full Text] [PDF]

MELANOMA
	Prognostic Significance of Occult Metastases Detected by Sentinel Lymphadenectomy and Reverse Transcriptase–Polymerase Chain Reaction in Early-Stage Melanoma Patients
	Peter J. Bostick, Donald L. Morton, Roderick R. Turner, Kelly T. Huynh, He-Jing Wang, Robert Elashoff, Richard Essner, and Dave S.B. Hoon
	JCO Oct 1 1999: 3238–3244. [Abstract] [Full Text] [PDF]
Counseling and DNA Testing for Individuals Perceived to Be Genetically Predisposed to Melanoma: A Consensus Statement of the Melanoma Genetics Consortium
Richard F. Kefford, Julia A. Newton Bishop, Wilma Bergman, and Margaret A. Tucker
JCO Oct 1 1999: 3245–3251. [Full Text] [PDF]

SARCOMAS
	Long-Term Outcomes After Function-Sparing Surgery Without Radiotherapy for Soft Tissue Sarcoma of the Extremities and Trunk
	Elizabeth H. Baldini, Joel Goldberg, Christopher Jenner, Judith B. Manola, George D. Demetri, Christopher D.M. Fletcher, and Samuel Singer
	JCO Oct 1 1999: 3252–3259. [Abstract] [Full Text] [PDF]
	Neoadjuvant Chemotherapy With Doxorubicin and Cisplatin in Malignant Fibrous Histiocytoma of Bone: A European Osteosarcoma Intergroup Study
	Vivien H.C. Bramwell, William P. Steward, Marianne Nooij, Jeremy Whelan, Alan W. Craft, Robert J. Grimer, Antonie H.M. Taminau, Steven R. Cannon, Archie J. Malcolm, Pancras C.W. Hogendoorn, Barbara Uscinska, Anne L. Kirkpatrick, David Machin, and Martine M. Van Glabbeke
	JCO Oct 1 1999: 3260–3269. [Abstract] [Full Text] [PDF]

GASTROINTESTINAL CANCER
	Phase II Trial of Weekly Irinotecan Plus Cisplatin in Advanced Esophageal Cancer
	David H. Ilson, Leonard Saltz, Peter Enzinger, Ying Huang, Alice Kornblith, Marc Gollub, Eileen O'Reilly, Gary Schwartz, Julia DeGroff, Gladys Gonzalez, and David P. Kelsen
	JCO Oct 1 1999: 3270–3275. [Abstract] [Full Text] [PDF]
	Sequential Biochemical Modulation of Fluorouracil With Folinic Acid, N-Phosphonacetyl-L-Aspartic Acid, and Interferon Alfa-2a in Advanced Colorectal Cancer
	Melanie E Royce, William McGarry, Beth Bready, Shaker R. Dakhil, Robert J. Belt, J. Wendall Goodwin, Richard Gray, Paulo M. Hoff, Rodger Winn, and Richard Pazdur
	JCO Oct 1 1999: 3276–3282. [Abstract] [Full Text] [PDF]

RADIATION ONCOLOGY
	Striking Regression of Chronic Radiotherapy Damage in a Clinical Trial of Combined Pentoxifylline and Tocopherol
	Sylvie Delanian, Saida Balla-Mekias, and Jean-Louis Lefaix
	JCO Oct 1 1999: 3283–3290. [Abstract] [Full Text] [PDF]

EPIDEMIOLOGY
	Dietary Fat and Carbohydrates Are Independently Associated With Circulating Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor–Binding Protein 3 Concentrations in Healthy Adults
	Virginia G. Kaklamani, Athena Linos, Evangelia Kaklamani, Ioanna Markaki, Yvonni Koumantaki, and Christos S. Mantzoros
	JCO Oct 1 1999: 3291–3298. [Abstract] [Full Text] [PDF]

SUPPORTIVE CARE AND QUALITY OF LIFE
	Randomized Comparison of Megestrol Acetate Versus Dexamethasone Versus Fluoxymesterone for the Treatment of Cancer Anorexia/Cachexia
	Charles L. Loprinzi, John W. Kugler, Jeff A. Sloan, James A. Mailliard, James E. Krook, Mary B. Wilwerding, Kendrith M. Rowland, Jr, John K. Camoriano, Paul J. Novotny, and Bradley J. Christensen
	JCO Oct 1 1999: 3299–3306. [Abstract] [Full Text] [PDF]
	Rapid Switching From Morphine to Methadone in Cancer Patients With Poor Response to Morphine
	Sebastiano Mercadante, Alessandra Casuccio, and Luciano Calderone
	JCO Oct 1 1999: 3307–3312. [Abstract] [Full Text] [PDF]
	Strategic Physician Communication and Oncology Clinical Trials
	Terrance L. Albrecht, Christina Blanchard, John C. Ruckdeschel, Michael Coovert, and Rebecca Strongbow
	JCO Oct 1 1999: 3324–3332. [Abstract] [Full Text] [PDF]

PHASE I AND CLINICAL PHARMACOLOGY
	Immunotherapy of Advanced Malignancy by Direct Gene Transfer of an Interleukin-2 DNA/DMRIE/DOPE Lipid Complex: Phase I/II Experience
	E. Galanis, E. M. Hersh, A. T. Stopeck, R. Gonzalez, P. Burch, C. Spier, E. T. Akporiaye, J. J. Rinehart, J. Edmonson, R. E. Sobol, C. Forscher, V. K. Sondak, B. D. Lewis, E. C. Unger, M. O'Driscoll, L. Selk, and J. Rubin
	JCO Oct 1 1999: 3313–3323. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLES
	American Society of Clinical Oncology Clinical Practice Guidelines for the Use of Chemotherapy and Radiotherapy Protectants
	Martee L. Hensley, Lynn M. Schuchter, Celeste Lindley, Neal J. Meropol, Gary I. Cohen, Gail Broder, William J. Gradishar, Daniel M. Green, Robert J. Langdon, Jr, R. Brian Mitchell, Robert Negrin, Ted P. Szatrowski, J. Tate Thigpen, Daniel Von Hoff, Todd H. Wasserman, Eric P. Winer, and David G. Pfister
	JCO Oct 1 1999: 3333–3355. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Choroidal Metastases

Michele R. Piccone, Albert M. Maguire, Kevin C. Fox, and Kym Gendron

JCO Oct 1 1999: 3356–3358. [Full Text] [PDF]

Choroidal Metastases

Corey Cutler and Evangelos S. Gragoudas

JCO Oct 1 1999: 3358–3359. [Full Text] [PDF]

CORRESPONDENCE

Impact of American Society of Clinical Oncology Guidelines for Clinical Use of Colony-Stimulating Factors

I. Debrix, C. Bouleuc, H. Liote, B. Milleron, A. Beker, Charles L. Bennett, and Mark R. Somerfield

JCO Oct 1 1999: 3360–3361. [Full Text] [PDF]

Clinical Course of Stage IV Epithelial Ovarian Cancer

Richard T. Penson, Steven J. Skates, Arlan J. Fuller, Jr, and Michael V. Seiden

JCO Oct 1 1999: 3361–3362. [Full Text] [PDF]

Current Status of Oral Anticancer Drugs in Japan

Yasuhiro Fujiwara

JCO Oct 1 1999: 3362–3365. [Full Text] [PDF]

SPECIAL DEPARTMENTS

ERRATA

Correction for vol. 17, p. 2334

JCO Oct 1 1999: 3365. [Full Text] [PDF]

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