EDITORIALS

Breast Cancer in Carriers of BRCA1 and BRCA2 Mutations: Tackling a Molecular and Clinical Conundrum

Daniel A. Haber

JCO Nov 1 1999: 3367–3370. [Full Text] [PDF]

Prostate Cancer Management Under Scrutiny: One Man's Meta-Analysis Is Another Man's Poisson

Derek Raghavan

JCO Nov 1 1999: 3371–3373. [Full Text] [PDF]

RAPID PUBLICATIONS
	Further Evaluation of Intensified and Increased Total Dose of Cyclophosphamide for the Treatment of Primary Breast Cancer: Findings From National Surgical Adjuvant Breast and Bowel Project B-25
	Bernard Fisher, Stewart Anderson, Arthur DeCillis, Nikolay Dimitrov, James N. Atkins, Louis Fehrenbacher, Patrick H. Henry, Edward H. Romond, Keith S. Lanier, Enrique Davila, Carl G. Kardinal, Leslie Laufman, H. Irving Pierce, Neil Abramson, Alan M. Keller, John T. Hamm, D.L. Wickerham, Mirsada Begovic, Elizabeth Tan-Chiu, Wei Tian, and Norman Wolmark
	JCO Nov 1 1999: 3374–3388. [Abstract] [Full Text] [PDF]
	Procarbazine, Lomustine, and Vincristine (PCV) Chemotherapy for Anaplastic Astrocytoma: A Retrospective Review of Radiation Therapy Oncology Group Protocols Comparing Survival With Carmustine or PCV Adjuvant Chemotherapy
	Michael D. Prados, Charles Scott, Walter J. Curran, Jr, Diana F. Nelson, Steve Leibel, and Simon Kramer
	JCO Nov 1 1999: 3389–3395. [Abstract] [Full Text] [PDF]

BREAST CANCER
	Survival in Hereditary Breast Cancer Associated With Germline Mutations of BRCA2
	L. C. Verhoog, C.T.M. Brekelmans, C. Seynaeve, G. Dahmen, A. N. van Geel, C.C.M. Bartels, M.M.A. Tilanus-Linthorst, A. Wagner, P. Devilee, D.J.J. Halley, A.M.W. van den Ouweland, E. J. Meijers-Heijboer, and J.G.M. Klijn
	JCO Nov 1 1999: 3396–3402. [Abstract] [Full Text] [PDF]
	Randomized Trial of 3-Hour Versus 24-Hour Infusion of High-Dose Paclitaxel in Patients With Metastatic or Locally Advanced Breast Cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-26
	Roy E. Smith, Ann M. Brown, Eleftherios P. Mamounas, Stewart J. Anderson, Barry C. Lembersky, James H. Atkins, Henry R. Shibata, Luis Baez, Patricia A. DeFusco, Enrique Davila, Stuart J. Tipping, James D. Bearden, and Michael P. Thirlwell
	JCO Nov 1 1999: 3403–3411. [Abstract] [Full Text] [PDF]
	Prospective Evaluation of Paclitaxel Versus Combination Chemotherapy With Fluorouracil, Doxorubicin, and Cyclophosphamide as Neoadjuvant Therapy in Patients With Operable Breast Cancer
	Aman U. Buzdar, S. Eva Singletary, Richard L. Theriault, Daniel J. Booser, Vicente Valero, Nuhad Ibrahim, Terry L. Smith, Lina Asmar, Debra Frye, Nikki Manuel, Shu-Wan Kau, Marsha McNeese, Eric Strom, Kelly Hunt, Frederick Ames, and Gabriel N. Hortobagyi
	JCO Nov 1 1999: 3412–3417. [Abstract] [Full Text] [PDF]
	Multicenter, Phase II Trial of Exemestane as Third-Line Hormonal Therapy of Postmenopausal Women With Metastatic Breast Cancer
	S. Jones, C. Vogel, A. Arkhipov, L. Fehrenbacher, P. Eisenberg, B. Cooper, S. Honig, A. Polli, F. Whaley, E. di Salle, J. Tiffany, A. Consonni, and L. Miller
	JCO Nov 1 1999: 3418–3425. [Abstract] [Full Text] [PDF]
	Granulocyte-Macrophage Colony-Stimulating Factor Treatment Before Doxorubicin and Cyclophosphamide Chemotherapy Priming in Women With Early-Stage Breast Cancer
	Nathan L. Kobrinsky, Diane E. Sjolander, Mary S. Cheang, Ralph Levitt, and Preston D. Steen
	JCO Nov 1 1999: 3426–3430. [Abstract] [Full Text] [PDF]
	Phase II Trial of N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine.HCl and Doxorubicin Chemotherapy in Metastatic Breast Cancer: A National Cancer Institute of Canada Clinical Trials Group Study
	K. Khoo, L. Brandes, L. Reyno, A. Arnold, S. Dent, T. Vandenberg, D. Lebwohl, B. Fisher, and E. Eisenhauer
	JCO Nov 1 1999: 3431–3437. [Abstract] [Full Text] [PDF]

GENITOURINARY CANCER
	Micrometastases of Bone Marrow in Localized Prostate Cancer: Correlation With Established Risk Factors
	Dorothea Weckermann, Peter Müller, Friedhelm Wawroschek, Gunnar Krawczak, Gert Riethmüller, and Günter Schlimok
	JCO Nov 1 1999: 3438–3443. [Abstract] [Full Text] [PDF]
	Prospective Pilot Study of Sildenafil for Treatment of Postradiotherapy Erectile Dysfunction in Patients With Prostate Cancer
	Damien C. Weber, Sabine Bieri, John M. Kurtz, and Raymond Miralbell
	JCO Nov 1 1999: 3444–3449. [Abstract] [Full Text] [PDF]
	First-Line High-Dose Chemotherapy Compared With Standard-Dose PEB/VIP Chemotherapy in Patients With Advanced Germ Cell Tumors: A Multivariate and Matched-Pair Analysis
	C. Bokemeyer, C. Kollmannsberger, C. Meisner, A. Harstrick, J. Beyer, B. Metzner, J. T. Hartmann, H.-J. Schmoll, L. Einhorn, L. Kanz, and C. Nichols
	JCO Nov 1 1999: 3450–3456. [Abstract] [Full Text] [PDF]
	Positron Emission Tomography Scans in the Evaluation of Postchemotherapy Residual Masses in Patients With Seminoma
	Kristen N. Ganjoo, Rebecca J. Chan, Matt Sharma, and Lawrence H. Einhorn
	JCO Nov 1 1999: 3457–3460. [Abstract] [Full Text] [PDF]
	Eligibility and Response Guidelines for Phase II Clinical Trials in Androgen-Independent Prostate Cancer: Recommendations From the Prostate-Specific Antigen Working Group
	Glenn J. Bubley, Michael Carducci, William Dahut, Nancy Dawson, Danai Daliani, Mario Eisenberger, William D. Figg, Boris Freidlin, Susan Halabi, Gary Hudes, Maha Hussain, Richard Kaplan, Charles Myers, William Oh, Daniel P. Petrylak, Eddie Reed, Bruce Roth, Oliver Sartor, Howard Scher, Jonathan Simons, Vickie Sinibaldi, Eric J. Small, Matthew R. Smith, Donald L. Trump, Robin Vollmer, and George Wilding
	JCO Nov 1 1999: 3461–3467. [Abstract] [Full Text] [PDF] [Publisher's Note]

PEDIATRIC ONCOLOGY
	Indications for Radiotherapy and Chemotherapy After Complete Resection in Rhabdomyosarcoma: A Report From the Intergroup Rhabdomyosarcoma Studies I to III
	Suzanne L. Wolden, James R. Anderson, William M. Crist, John C. Breneman, Moody D. Wharam, Jr, Eugene S. Wiener, Stephen J. Qualman, and Sarah S. Donaldson
	JCO Nov 1 1999: 3468–3475. [Abstract] [Full Text] [PDF]
	Neurocognitive Development of Children After a Cerebellar Tumor in Infancy: A Longitudinal Study
	Donna R. Copeland, Carl deMoor, Bartlett D. Moore III, and Joann L. Ater
	JCO Nov 1 1999: 3476–3486. [Abstract] [Full Text] [PDF]
	Survival After Relapse in Children and Adolescents With Rhabdomyosarcoma: A Report From the Intergroup Rhabdomyosarcoma Study Group
	Alberto S. Pappo, James R. Anderson, William M. Crist, Moody D. Wharam, Phillip P. Breitfeld, Douglas Hawkins, R. Beverly Raney, Richard B. Womer, David M. Parham, Steven J. Qualman, and Holcombe E. Grier
	JCO Nov 1 1999: 3487–3493. [Abstract] [Full Text] [PDF]

SURGICAL ONCOLOGY
	Galectin-3 and CD44v6 Isoforms in the Preoperative Evaluation of Thyroid Nodules
	Alessandra Gasbarri, Marco Paolo Martegani, Fabrizio Del Prete, Teresa Lucante, Pier Giorgio Natali, and Armando Bartolazzi
	JCO Nov 1 1999: 3494–3502. [Abstract] [Full Text] [PDF]

HEAD AND NECK CANCER
	Phase II Trial of Docetaxel, Cisplatin, Fluorouracil, and Leucovorin as Induction for Squamous Cell Carcinoma of the Head and Neck
	A. D. Colevas, C. M. Norris, R. B. Tishler, M. P. Fried, H. I. Gomolin, P. Amrein, A. Nixon, C. Lamb, R. Costello, J. Barton, R. Read, S. Adak, and M. R. Posner
	JCO Nov 1 1999: 3503–3511. [Abstract] [Full Text] [PDF]
	Liposomal Doxorubicin and Conventionally Fractionated Radiotherapy in the Treatment of Locally Advanced Non–Small-Cell Lung Cancer and Head and Neck Cancer
	M. I. Koukourakis, S. Koukouraki, A. Giatromanolaki, S. C. Archimandritis, J. Skarlatos, K. Beroukas, J. G. Bizakis, G. Retalis, N. Karkavitsas, and E. S. Helidonis
	JCO Nov 1 1999: 3512–3521. [Abstract] [Full Text] [PDF]

LUNG CANCER
	Gemcitabine and Cisplatin Versus Mitomycin, Ifosfamide, and Cisplatin in Advanced Non–Small-Cell Lung Cancer: A Randomized Phase III Study of the Italian Lung Cancer Project
	L. Crinò, G. V. Scagliotti, S. Ricci, F. De Marinis, M. Rinaldi, C. Gridelli, A. Ceribelli, R. Bianco, M. Marangolo, F. Di Costanzo, M. Sassi, S. Barni, A. Ravaioli, V. Adamo, L. Portalone, G. Cruciani, A. Masotti, G. Ferrara, F. Gozzelino, and M. Tonato
	JCO Nov 1 1999: 3522–3530. [Abstract] [Full Text] [PDF]
	Multiple Courses of High-Dose Ifosfamide, Carboplatin, and Etoposide With Peripheral-Blood Progenitor Cells and Filgrastim for Small-Cell Lung Cancer: A Feasibility Study by the European Group for Blood and Marrow Transplantation
	S. Leyvraz, L. Perey, G. Rosti, A. Lange, S. Pampallona, R. Peters, Y. Humblet, L. Bosquée, F. Pasini, and M. Marangolo
	JCO Nov 1 1999: 3531–3539. [Abstract] [Full Text] [PDF]
	Phase II Study of Area Under the Plasma-Concentration-Versus-Time Curve–Based Carboplatin Plus Standard-Dose Intravenous Etoposide in Elderly Patients With Small-Cell Lung Cancer
	Hiroaki Okamoto, Koshiro Watanabe, Yutaka Nishiwaki, Kiyoshi Mori, Yuzoh Kurita, Izumi Hayashi, Masayuki Masutani, Koichiro Nakata, Satoshi Tsuchiya, Hiroshi Isobe, and Nagahiro Saijo
	JCO Nov 1 1999: 3540–3545. [Abstract] [Full Text] [PDF]
	Placebo-Controlled Trial of 13-cis-Retinoic Acid Activity on Retinoic Acid Receptor-Beta Expression in a Population at High Risk: Implications for Chemoprevention of Lung Cancer
	J. Ayoub, R. Jean-François, Y. Cormier, D. Meyer, Y. Ying, P. Major, C. Desjardins, and W.E.C. Bradley
	JCO Nov 1 1999: 3546–3552. [Abstract] [Full Text] [PDF]

GASTROINTESTINAL CANCER
	Clinical Trial to Assess the Relative Efficacy of Fluorouracil and Leucovorin, Fluorouracil and Levamisole, and Fluorouracil, Leucovorin, and Levamisole in Patients With Dukes' B and C Carcinoma of the Colon: Results From National Surgical Adjuvant Breast and Bowel Project C-04
	Norman Wolmark, Howard Rockette, Eleftherios Mamounas, Judy Jones, Sam Wieand, D.L. Wickerham, Harry D. Bear, James N. Atkins, Nikolay V. Dimitrov, Andrew G. Glass, Edwin R. Fisher, and Bernard Fisher
	JCO Nov 1 1999: 3553–3559. [Abstract] [Full Text] [PDF]
	Multicenter Phase II Study of Bimonthly High-Dose Leucovorin, Fluorouracil Infusion, and Oxaliplatin for Metastatic Colorectal Cancer Resistant to the Same Leucovorin and Fluorouracil Regimen
	Thierry André, Mohamed A. Bensmaine, Christophe Louvet, Eric François, Virginie Lucas, Françoise Desseigne, Karine Beerblock, Olivier Bouché, Elisabeth Carola, Yacine Merrouche, François Morvan, Ghislaine Dupont-André, and Aimery de Gramont
	JCO Nov 1 1999: 3560–3568. [Abstract] [Full Text] [PDF]

HEMATOLOGIC MALIGNANCIES
	Management of Acute Myeloid Leukemia in Elderly Patients
	Wolfgang Hiddemann, Wolfgang Kern, Claudia Schoch, Christa Fonatsch, Achim Heinecke, Bernhard Wörmann, and Thomas Büchner
	JCO Nov 1 1999: 3569–3576. [Abstract] [Full Text] [PDF]
	Decision Analysis on Alternative Treatment Strategies for Favorable-Prognosis, Early-Stage Hodgkin's Disease
	Andrea K. Ng, Jane C. Weeks, Peter M. Mauch, and Karen M. Kuntz
	JCO Nov 1 1999: 3577–3585. [Abstract] [Full Text] [PDF]

PHASE I AND CLINICAL PHARMACOLOGY
	Phase I Evaluation of ISIS 3521, an Antisense Oligodeoxynucleotide to Protein Kinase C-Alpha, in Patients With Advanced Cancer
	J. Nemunaitis, J. T. Holmlund, M. Kraynak, D. Richards, J. Bruce, N. Ognoskie, T. J. Kwoh, R. Geary, A. Dorr, D. Von Hoff, and S. G. Eckhardt
	JCO Nov 1 1999: 3586–3595. [Abstract] [Full Text] [PDF]
	Cardiotoxicity of Epirubicin/Paclitaxel–Containing Regimens: Role of Cardiac Risk Factors
	Alessandra Gennari, Barbara Salvadori, Sara Donati, Carmelo Bengala, Cinzia Orlandini, Romano Danesi, Mario Del Tacca, Paolo Bruzzi, and Pier Franco Conte
	JCO Nov 1 1999: 3596–3602. [Abstract] [Full Text] [PDF]

SUPPORTIVE CARE AND QUALITY OF LIFE
	Quality-of-Life Measurement in Advanced Cancer: Assessing the Individual
	Dympna Waldron, Ciaran A. O'Boyle, Michael Kearney, Michael Moriarty, and Desmond Carney
	JCO Nov 1 1999: 3603–3611. [Abstract] [Full Text] [PDF]
	Subjective and Objective Prospective, Long-Term Analysis of Quality of Life During Inhaled Interleukin-2 Immunotherapy
	Hans Heinzer, Thomas S. Mir, Edith Huland, and Hartwig Huland
	JCO Nov 1 1999: 3612–3620. [Abstract] [Full Text] [PDF]
	Assessing the Reliability of Patient, Nurse, and Family Caregiver Symptom Ratings in Hospitalized Advanced Cancer Patients
	Cheryl L. Nekolaichuk, Thomas O. Maguire, Maria Suarez-Almazor, W. Todd Rogers, and Eduardo Bruera
	JCO Nov 1 1999: 3621–3630. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Ras Protein Farnesyltransferase: A Strategic Target for Anticancer Therapeutic Development
	Eric K. Rowinsky, Jolene J. Windle, and Daniel D. Von Hoff
	JCO Nov 1 1999: 3631–3652. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	Breast Carcinomas Arising in Carriers of Mutations in BRCA1 or BRCA2: Are They Prognostically Different?
	Kelly-Anne Phillips, Irene L. Andrulis, and Pamela J. Goodwin
	JCO Nov 1 1999: 3653–3663. [Abstract] [Full Text] [PDF]
	Treatment of Locally Advanced Prostate Cancer: Is Chemotherapy the Next Step?
	William K. Oh and Philip W. Kantoff
	JCO Nov 1 1999: 3664–3675. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLES
	Use of Hematopoietic Colony-Stimulating Factors: Comparison of the 1994 and 1997 American Society of Clinical Oncology Surveys Regarding ASCO Clinical Practice Guidelines
	Charles L. Bennett, Jane A. Weeks, Mark R. Somerfield, Joe Feinglass, and Thomas J. Smith
	JCO Nov 1 1999: 3676–3681. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Primary Low-Grade Lymphomas of the Intestine

Taner Demirer, Harika Çelebi, Ender Akçaglayan, Celalettin Üstün, Seher Demirer, Cemil Ekinci, Kadir Bahar, and Haluk Koç

JCO Nov 1 1999: 3682–3684. [Full Text] [PDF]

Primary Low-Grade Lymphomas of the Intestine

C. S. Chim, C. Choy, G. C. Ooi, and R. Liang

JCO Nov 1 1999: 3684–3688. [Full Text] [PDF]

CORRESPONDENCE

BRCA1/BRCA2 in Breast-Conserving Therapy

Bruce C. Turner, Peter M. Glazer, Bruce G. Haffty, and Samuel Hellman

JCO Nov 1 1999: 3689-a. [Full Text] [PDF]

Tamoxifen and Sexuality: Let's Listen to the Data Speak

Jonathan J. Beitler, Joanne E. Mortimer, and Diane Knapp

JCO Nov 1 1999: 3689-b–3690. [Full Text] [PDF]

Fluorescence In Situ Hybridization Versus Immunohistochemistry: Importance of Clinical Outcome

Steven Seelig, Timothy W. Jacobs, Stuart J. Schnitt, Allen M. Gown, and Hadi Yaziji

JCO Nov 1 1999: 3690-b–3692. [Full Text] [PDF]

Phase I Trial Dosing of Gemcitabine and Concurrent Involved Field Irradiation in Patients With Localized Pancreatic Carcinomas

John J. Nanfro, A. William Blackstock, and Joel E. Tepper

JCO Nov 1 1999: 3692-a. [Full Text] [PDF]

CD20-Negative Relapse After 131I–Anti-CD20 Therapy

P. Venugopal, W. T. Leslie, T. O'Brien, and S. A. Gregory

JCO Nov 1 1999: 3692-b–3693. [Full Text] [PDF]

SPECIAL DEPARTMENTS

ERRATA

Correction for vol. 17, p. 2762

JCO Nov 1 1999: 3693-b. [Full Text] [PDF]

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