EDITORIALS

Increased Dose-Intensity in Small-Cell Lung Cancer: A Failed Strategy?

David H. Johnson and David P. Carbone

JCO Aug 1 1999: 2297. [Full Text] [PDF]

LUNG CANCER
	Randomized Study of CODE Versus Alternating CAV/EP for Extensive-Stage Small-Cell Lung Cancer: An Intergroup Study of the National Cancer Institute of Canada Clinical Trials Group and the Southwest Oncology Group
	Nevin Murray, Robert B. Livingston, Frances A. Shepherd, Keith James, Benny Zee, A. Langleben, Michael Kraut, James Bearden, J. Wendall Goodwin, Clive Grafton, Andrew Turrisi, David Walde, Herbert Croft, David Osoba, Jon Ottaway, and David Gandara
	JCO Aug 1 1999: 2300. [Abstract] [Full Text] [PDF]
	Cisplatin, Etoposide, and Paclitaxel in the Treatment of Patients With Extensive Small-Cell Lung Carcinoma
	Bonnie S. Glisson, Jonathan M. Kurie, Roman Perez-Soler, Nikolous J. Fox, William K. Murphy, Frank V. Fossella, Jin S. Lee, Michael B. Ross, David A. Nyberg, Katherine M.W. Pisters, Dong M. Shin, and Waun Ki Hong
	JCO Aug 1 1999: 2309. [Abstract] [Full Text] [PDF]
	Cisplatin, Gemcitabine, and Paclitaxel in Locally Advanced or Metastatic Non–Small-Cell Lung Cancer: A Phase I-II Study
	Giuseppe Frasci, Nicola Panza, Pasquale Comella, Gianpaolo P. Nicolella, Michele Natale, Luigi Manzione, Domenico Bilancia, Riccardo Cioffi, Luigi Maiorino, Giuseppe De Cataldis, Mario Belli, Enrico Micillo, Vittorio Mascia, Bruno Massidda, Vito Lorusso, Mario De Lena, Francesco Carpagnano, Antonio Contu, Guido Pusceddu, and Giuseppe Comella
	JCO Aug 1 1999: 2316. [Abstract] [Full Text] [PDF]

BREAST CANCER
	10-Year Results After Sector Resection With or Without Postoperative Radiotherapy for Stage I Breast Cancer: A Randomized Trial
	G. Liljegren, L. Holmberg, J. Bergh, A. Lindgren, L. Tabár, H. Nordgren, and H.O. Adami
	JCO Aug 1 1999: 2326. [Abstract] [Full Text] [PDF]
	Significance of Axillary Lymph Node Metastasis in Primary Breast Cancer
	Ismail Jatoi, Susan G. Hilsenbeck, Gary M. Clark, and C. Kent Osborne
	JCO Aug 1 1999: 2334. [Abstract] [Full Text] [PDF]
	Prospective Randomized Trial of Docetaxel Versus Doxorubicin in Patients With Metastatic Breast Cancer
	Stephen Chan, Kay Friedrichs, Daniel Noel, Tamàs Pintér, Simon Van Belle, Daniel Vorobiof, Ricardo Duarte, Miguel Gil Gil, Istvan Bodrogi, Elizabeth Murray, Louise Yelle, Gunter von Minckwitz, Stefan Korec, Peter Simmonds, Franco Buzzi, Rosario González Mancha, Gary Richardson, Euan Walpole, Monica Ronzoni, Michael Murawsky, May Alakl, Alessandro Riva, and John Crown
	JCO Aug 1 1999: 2341. [Abstract] [Full Text] [PDF]
	Initial Paclitaxel Improves Outcome Compared With CMFP Combination Chemotherapy as Front-Line Therapy in Untreated Metastatic Breast Cancer
	James F. Bishop, Joanna Dewar, Guy C. Toner, Jennifer Smith, Martin H.N. Tattersall, Ian N. Olver, Stephen Ackland, Ian Kennedy, David Goldstein, Howard Gurney, Euan Walpole, John Levi, Jennifer Stephenson, and Renzo Canetta
	JCO Aug 1 1999: 2355. [Abstract] [Full Text] [PDF]
	Risk of Menopause During the First Year After Breast Cancer Diagnosis
	Pamela J. Goodwin, Marguerite Ennis, Kathleen I. Pritchard, Maureen Trudeau, and Nicky Hood
	JCO Aug 1 1999: 2365. [Abstract] [Full Text] [PDF]
	Predictors of Sexual Health in Women After a Breast Cancer Diagnosis
	Patricia A. Ganz, Katherine A. Desmond, Thomas R. Belin, Beth E. Meyerowitz, and Julia H. Rowland
	JCO Aug 1 1999: 2371. [Abstract] [Full Text] [PDF]
	Early Detection and Accurate Description of Extent of Metastatic Bone Disease in Breast Cancer With Fluoride Ion and Positron Emission Tomography
	Holger Schirrmeister, Albrecht Guhlmann, Jörg Kotzerke, Claudia Santjohanser, Thorsten Kühn, Rolf Kreienberg, Peter Messer, Karin Nüssle, Klaus Elsner, Gerhard Glatting, Harald Träger, Bernd Neumaier, Christoph Diederichs, and Sven N. Reske
	JCO Aug 1 1999: 2381. [Abstract] [Full Text] [PDF]

HEAD AND NECK CANCER
	Phase I/II Trial of Radiation With Chemotherapy "Boost" for Advanced Squamous Cell Carcinomas of the Head and Neck: Toxicities and Responses
	Adam S. Garden, Bonnie S. Glisson, K. Kian Ang, William H. Morrison, Scott M. Lippman, Robert M. Byers, Fady Geara, Gary L. Clayman, Dong M. Shin, David L. Callender, Fadlo R. Khuri, Helmuth Goepfert, Waun K. Hong, and Lester J. Peters
	JCO Aug 1 1999: 2390. [Abstract] [Full Text] [PDF]

GASTROINTESTINAL CANCER
	Influence of the Interval Between Preoperative Radiation Therapy and Surgery on Downstaging and on the Rate of Sphincter-Sparing Surgery for Rectal Cancer: The Lyon R90-01 Randomized Trial
	Yves Francois, Chantal J. Nemoz, Jacques Baulieux, Jacques Vignal, Jean-Paul Grandjean, Christian Partensky, Jean Christophe Souquet, Patrice Adeleine, and Jean-Pierre Gerard
	JCO Aug 1 1999: 2396. [Abstract] [Full Text] [PDF]
	Enhanced Staging and All Chemotherapy Preoperatively in Patients with Potentially Resectable Gastric Carcinoma
	Jaffer A. Ajani, Paul F. Mansfield, Patrick M. Lynch, Peter W. Pisters, Barry Feig, Pamela Dumas, Douglas B. Evans, Issac Raijman, Kristin Hargraves, Stephen Curley, and David M. Ota
	JCO Aug 1 1999: 2403. [Abstract] [Full Text] [PDF]
	Adjuvant or Palliative Chemotherapy for Colorectal Cancer in Patients 70 Years or Older
	R. A. Popescu, A. Norman, P. J. Ross, B. Parikh, and D. Cunningham
	JCO Aug 1 1999: 2412. [Abstract] [Full Text] [PDF]
	Nerve Growth Factor Expression Correlates With Perineural Invasion and Pain in Human Pancreatic Cancer
	Zhaowen Zhu, Helmut Friess, Fabio F. diMola, Arthur Zimmermann, Hans U. Graber, Murray Korc, and Markus W. Büchler
	JCO Aug 1 1999: 2419. [Abstract] [Full Text] [PDF]
	Medullary-Type Poorly Differentiated Adenocarcinoma of the Large Bowel: A Distinct Clinicopathologic Entity Characterized by Microsatellite Instability and Improved Survival
	Giovanni Lanza, Roberta Gafà, Maurizio Matteuzzi, and Alessandra Santini
	JCO Aug 1 1999: 2429. [Abstract] [Full Text] [PDF]
	Eniluracil Treatment Completely Inactivates Dihydropyrimidine Dehydrogenase in Colorectal Tumors
	Fareeda Y. Ahmed, Stephen J. Johnston, James Cassidy, Terry O'Kelly, Norman Binnie, Graeme I. Murray, Albert H. van Gennip, Nico G.G.M. Abeling, Sidonie Knight, and Howard L. McLeod
	JCO Aug 1 1999: 2439. [Abstract] [Full Text] [PDF]

HEMATOLOGIC MALIGNANCIES
	Analysis of Factors That Correlate With Mucositis in Recipients of Autologous and Allogeneic Stem-Cell Transplants
	Aaron P. Rapoport, Luc F. Miller Watelet, Tammy Linder, Shirley Eberly, Richard F. Raubertas, Joanna Lipp, Reggie Duerst, Camille N. Abboud, Louis Constine, Jessica Andrews, Mary Ann Etter, Linda Spear, Elizabeth Powley, Charles H. Packman, Jacob M. Rowe, Ullrich Schwertschlag, Camille Bedrosian, and Jane L. Liesveld
	JCO Aug 1 1999: 2446. [Abstract] [Full Text] [PDF]
	Second Malignancies as a Consequence of Nucleoside Analog Therapy for Chronic Lymphoid Leukemias
	Bruce D. Cheson, Donald A. Vena, Jane Barrett, and Boris Freidlin
	JCO Aug 1 1999: 2454. [Abstract] [Full Text] [PDF]
	Hyper-CVAD Program in Burkitt's-Type Adult Acute Lymphoblastic Leukemia
	Deborah A. Thomas, Jorge Cortes, Susan O'Brien, Sherry Pierce, Stefan Faderl, Maher Albitar, Frederick B. Hagemeister, Fernando F. Cabanillas, Sharon Murphy, Michael J. Keating, and Hagop Kantarjian
	JCO Aug 1 1999: 2461. [Abstract] [Full Text] [PDF]
	Treatment of Multifocal Primary Cutaneous B-Cell Lymphoma: A Clinical Follow-Up Study of 29 Patients
	Marcel W. Bekkenk, Maarten H. Vermeer, Marie-Louise Geerts, Ed M. Noordijk, Freerk Heule, Pieter C. van Voorst Vader, Willem A. van Vloten, Chris J.L.M. Meijer, and Rein Willemze
	JCO Aug 1 1999: 2471. [Abstract] [Full Text] [PDF]
	CNS Involvement in Primary Mediastinal Large B-Cell Lymphoma
	Philippe C. Bishop, Wyndham H. Wilson, Debra Pearson, John Janik, Elaine S. Jaffe, and Patrick C. Elwood
	JCO Aug 1 1999: 2479. [Abstract] [Full Text] [PDF]
	Marginal Zone B-Cell Lymphoma: A Clinical Comparison of Nodal and Mucosa-Associated Lymphoid Tissue Types
	Bharat N. Nathwani, James R. Anderson, James O. Armitage, Franco Cavalli, Jacques Diebold, Milton R. Drachenberg, Nancy L. Harris, Kenneth A. MacLennan, H. Konrad Müller-Hermelink, Fred A. Ullrich, and Dennis D. Weisenburger
	JCO Aug 1 1999: 2486. [Abstract] [Full Text] [PDF]
	Assessment and Significance of Mediastinal Bulk in Hodgkin's Disease: Comparison Between Computed Tomography and Chest Radiography
	A. J. Bradley, B. M. Carrington, J. A.L. Lawrance, W. D.J. Ryder, and J. A. Radford
	JCO Aug 1 1999: 2493. [Abstract] [Full Text] [PDF]
	Low-Grade Stage III-IV Follicular Lymphoma: Multivariate Analysis of Prognostic Factors in 484 Patients—A Study of the Groupe d'Etude des Lymphomes de l'Adulte
	Didier Decaudin, Eric Lepage, Nicole Brousse, Pauline Brice, Jean-Luc Harousseau, Karim Belhadj, Hervé Tilly, Lucienne Michaux, Stéphane Chèze, Bertrand Coiffier, and Philippe Solal-Céligny
	JCO Aug 1 1999: 2499. [Abstract] [Full Text] [PDF]

GENITOURINARY CANCER
	Hydrocortisone With or Without Mitoxantrone in Men With Hormone-Refractory Prostate Cancer: Results of the Cancer and Leukemia Group B 9182 Study
	Philip W. Kantoff, Susan Halabi, Mark Conaway, Joel Picus, Jeffrey Kirshner, Vera Hars, Donald Trump, Eric P. Winer, and Nicholas J. Vogelzang
	JCO Aug 1 1999: 2506. [Abstract] [Full Text] [PDF]
	Patient Selection for Salvage Cryotherapy for Locally Recurrent Prostate Cancer After Radiation Therapy
	Louis L. Pisters, Paul Perrotte, Shellie M. Scott, Graham F. Greene, and Andrew C. von Eschenbach
	JCO Aug 1 1999: 2514. [Abstract] [Full Text] [PDF]
	Multicenter, Randomized, Phase III Trial of CD8+ Tumor-Infiltrating Lymphocytes in Combination With Recombinant Interleukin-2 in Metastatic Renal Cell Carcinoma
	Robert A. Figlin, John A. Thompson, Ronald M. Bukowski, Nicholas J. Vogelzang, Andrew C. Novick, Paul Lange, Gary D. Steinberg, and Arie S. Belldegrun
	JCO Aug 1 1999: 2521. [Abstract] [Full Text] [PDF]
	Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
	Robert J. Motzer, Madhu Mazumdar, Jennifer Bacik, William Berg, Alison Amsterdam, and Joseph Ferrara
	JCO Aug 1 1999: 2530. [Abstract] [Full Text] [PDF]
	Multi-Institutional Study of the Angiogenesis Inhibitor TNP-470 in Metastatic Renal Carcinoma
	Walter M. Stadler, Timothy Kuzel, Charles Shapiro, Jeffery Sosman, Joseph Clark, and Nicholas J. Vogelzang
	JCO Aug 1 1999: 2541. [Abstract] [Full Text] [PDF]
	Outcome of Postchemotherapy Surgery After Treatment With Methotrexate, Vinblastine, Doxorubicin, and Cisplatin in Patients With Unresectable or Metastatic Transitional Cell Carcinoma
	Paul M. Dodd, John A. McCaffrey, Harry Herr, Madhu Mazumdar, Jennifer Bacik, Geralyn Higgins, Mary G. Boyle, Howard I. Scher, and Dean F. Bajorin
	JCO Aug 1 1999: 2546. [Abstract] [Full Text] [PDF]

GYNECOLOGIC CANCER
	Activity and Pharmacodynamics of 21-Day Topotecan Infusion in Patients With Ovarian Cancer Previously Treated With Platinum-Based Chemotherapy
	Howard Hochster, Scott Wadler, Carolyn Runowicz, Leonard Liebes, Henry Cohen, Robert Wallach, Joan Sorich, Beth Taubes, and James Speyer
	JCO Aug 1 1999: 2553. [Abstract] [Full Text] [PDF]

MELANOMA
	MART-1 Is Expressed Less Frequently on Circulating Melanoma Cells in Patients Who Develop Distant Compared With Locoregional Metastases
	Benjamin J. Curry, Kieda Myers, and Peter Hersey
	JCO Aug 1 1999: 2562. [Abstract] [Full Text] [PDF]

BRAIN TUMORS
	Outcomes and Prognostic Factors in Recurrent Glioma Patients Enrolled Onto Phase II Clinical Trials
	Eric T. Wong, Kenneth R. Hess, Mary Jo Gleason, Kurt A. Jaeckle, Athanassios P. Kyritsis, Michael D. Prados, Victor A. Levin, and W.K. Alfred Yung
	JCO Aug 1 1999: 2572. [Abstract] [Full Text] [PDF]
	KRN8602 (MX2-Hydrochloride): An Active New Agent for the Treatment of Recurrent High-Grade Glioma
	Kerrie Clarke, Russell L. Basser, Craig Underhill, Peter Mitchell, Jane Bartlett, Lawrence Cher, Michael Findlay, David Dalley, Malcolm Pell, Michael Byrne, Howard Geldard, John S. Hill, Darryl Maher, Richard M. Fox, Michael D. Green, and Andrew H. Kaye
	JCO Aug 1 1999: 2579. [Abstract] [Full Text] [PDF]
	Radiation Therapy for Intracranial Germinoma: Results of the German Cooperative Prospective Trials MAKEI 83/86/89
	Michael Bamberg, Rolf-D. Kortmann, Gabriele Calaminus, Gerd Becker, Christoph Meisner, Dieter Harms, and Ulrich Göbel
	JCO Aug 1 1999: 2585. [Abstract] [Full Text] [PDF]

PHASE I AND CLINICAL PHARMACOLOGY
	Phase I Trial to Determine the Safety, Pharmacodynamics, and Pharmacokinetics of RSR13, a Novel Radioenhancer, in Newly Diagnosed Glioblastoma Multiforme
	L. Kleinberg, S. A. Grossman, S. Piantadosi, J. Pearlman, H. Engelhard, G. Lesser, J. Ruffer, and M. Gerber
	JCO Aug 1 1999: 2593. [Abstract] [Full Text] [PDF]
	Phase I and Pharmacokinetic Study of Temozolomide on a Daily-for-5-Days Schedule in Patients With Advanced Solid Malignancies
	Lisa A. Hammond, John R. Eckardt, Sharyn D. Baker, S. Gail Eckhardt, Margaret Dugan, Kelly Forral, Pascale Reidenberg, Paul Statkevich, Geoffrey R. Weiss, David A. Rinaldi, Daniel D. Von Hoff, and Eric K. Rowinsky
	JCO Aug 1 1999: 2604. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLES
	Proposed Agenda for the Measurement of Quality-of-Care Outcomes in Oncology Practice
	Jeanne S. Mandelblatt, Patricia A. Ganz, and Katherine L. Kahn
	JCO Aug 1 1999: 2614. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Large Bowel Adenocarcinoma Metastases Presenting as Appendicitis

Barbara Heller, John Kane, Remedios Penetrante, Tom Weber, Miguel Rodriguez-Bigas, and Nicholas Petrelli

JCO Aug 1 1999: 2623. [Full Text] [PDF]

CORRESPONDENCE

Institutional Review Board Review of Research Reported in the Journal of Clinical Oncology Response Response

George J. Hill, Katherine K. Matthay, Brian H. Kushner, Nai-Kong V. Cheung, and Michael P. LaQuaglia

JCO Aug 1 1999: 2625-a. [Full Text] [PDF]

Gemcitabine and Cisplatin: Second-Line Chemotherapy for Malignant Mesothelioma? Response

Nicholas J. Vogelzang, Michael J. Byrne, Joanna Dewar, and Guy van Hazel

JCO Aug 1 1999: 2625-b. [Full Text] [PDF]

Gemcitabine Is Active in Relapsed Hodgkin's Disease

Jennifer B. Lucas, Steven M. Horwitz, Sandra J. Horning, and Antoine Sayegh

JCO Aug 1 1999: 2625-c. [Full Text] [PDF]

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