IN MEMORIAM

Raymond Alexanian, Kenneth Anderson, Bart Barlogie, James Berenson, William S. Dalton, and Robert A. Kyle

JCO Jan 5 2000: 1. [Full Text] [PDF]

EDITORIALS

A New Addition to the Journal of Clinical Oncology: The Art of Oncology—When the Tumor Is Not the Target

Charles L. Loprinzi and George P. Canellos

JCO Jan 5 2000: 3. [Full Text] [PDF]

PEDIATRIC ONCOLOGY
	Prognostic Factors in Nonmetastatic Ewing’s Sarcoma of Bone Treated With Adjuvant Chemotherapy: Analysis of 359 Patients at the Istituto Ortopedico Rizzoli
	Gaetano Bacci, Stefano Ferrari, Franco Bertoni, Simonetta Rimondini, Alessandra Longhi, Patrizia Bacchini, Cristiana Forni, Marco Manfrini, Davide Donati, and Piero Picci
	JCO Jan 5 2000: 4. [Abstract] [Full Text] [PDF]
	Chemoreduction and Local Ophthalmic Therapy for Intraocular Retinoblastoma
	Debra L. Friedman, Bruce Himelstein, Carol L. Shields, Jerry A. Shields, Michael Needle, David Miller, Greta R. Bunin, and Anna T. Meadows
	JCO Jan 5 2000: 12. [Abstract] [Full Text] [PDF]
	Biologic Variables in the Outcome of Stages I and II Neuroblastoma Treated With Surgery as Primary Therapy: A Children’s Cancer Group Study
	Carlos A. Perez, Katherine K. Matthay, James B. Atkinson, Robert C. Seeger, Hiroyuki Shimada, Gerald M. Haase, Daniel O. Stram, Robert B. Gerbing, and John N. Lukens
	JCO Jan 5 2000: 18. [Abstract] [Full Text] [PDF]
	Angiogenesis in Neuroblastoma: Relationship to Survival and Other Prognostic Factors in a Cohort of Neuroblastoma Patients
	A. Cañete, S. Navarro, J. Bermúdez, A. Pellín, V. Castel, and A. Llombart-Bosch
	JCO Jan 5 2000: 27. [Abstract] [Full Text] [PDF]

HEAD AND NECK CANCER
	Is Radiation Therapy a Preferred Alternative to Surgery for Squamous Cell Carcinoma of the Base of Tongue?
	William M. Mendenhall, Scott P. Stringer, Robert J. Amdur, Russell W. Hinerman, Giselle J. Moore-Higgs, and Nicholas J. Cassisi
	JCO Jan 5 2000: 35. [Abstract] [Full Text] [PDF]

HEMATOLOGIC MALIGNANCIES
	Randomized Trial of Filgrastim, Sargramostim, or Sequential Sargramostim and Filgrastim After Myelosuppressive Chemotherapy for the Harvesting of Peripheral-Blood Stem Cells
	Charles H. Weaver, Kevin A. Schulman, Barbara Wilson-Relyea, Robert Birch, William West, and C. Dean Buckner
	JCO Jan 1 2000: 43. [Abstract] [Full Text] [PDF]
	Angiocentric Lymphoma of the Head and Neck: Patterns of Systemic Failure After Radiation Treatment
	Gwi Eon Kim, Jae Ho Cho, Woo Ick Yang, Eun Ji Chung, Chang Ok Suh, Kyung Ran Park, Won Pyo Hong, In Yong Park, Jee Sook Hahn, Jae Kyung Roh, and Byung Soo Kim
	JCO Jan 1 2000: 54. [Abstract] [Full Text] [PDF]
	Predicting Costs of Stem-Cell Transplantation
	Stephanie J. Lee, Neil Klar, Jane C. Weeks, and Joseph H. Antin
	JCO Jan 5 2000: 64. [Abstract] [Full Text] [PDF]

BREAST CANCER
	Pamidronate in Prevention of Bone Complications in Metastatic Breast Cancer: A Cost-Effectiveness Analysis
	Bruce E. Hillner, Jane C. Weeks, Christopher E. Desch, and Thomas J. Smith
	JCO Jan 1 2000: 72. [Abstract] [Full Text] [PDF]
	Lack of Effect of Adjuvant Chemotherapy on the Elimination of Single Dormant Tumor Cells in Bone Marrow of High-Risk Breast Cancer Patients
	Stephan Braun, Christina Kentenich, Wolfgang Janni, Florian Hepp, Johann de Waal, Fritz Willgeroth, Harald Sommer, and Klaus Pantel
	JCO Jan 5 2000: 80. [Abstract] [Full Text] [PDF]
	Reduced MLH1 Expression in Breast Tumors After Primary Chemotherapy Predicts Disease-Free Survival
	H. J. Mackay, D. Cameron, M. Rahilly, M. J. Mackean, J. Paul, S. B. Kaye, and R. Brown
	JCO Jan 5 2000: 87. [Abstract] [Full Text] [PDF]
	Randomized 2 x 2 Trial Evaluating Hormonal Treatment and the Duration of Chemotherapy in Node-Positive Breast Cancer Patients: An Update Based on 10 Years’ Follow-Up
	W. Sauerbrei, G. Bastert, H. Bojar, C. Beyerle, R. L. A. Neumann, C. Schmoor, and M. Schumacher
	JCO Jan 5 2000: 94. [Abstract] [Full Text] [PDF]

GYNECOLOGIC CANCER
	Paclitaxel-Associated Hypersensitivity Reactions: Experience of the Gynecologic Oncology Program of the Cleveland Clinic Cancer Center
	Maurie Markman, Alexander Kennedy, Kenneth Webster, Barbara Kulp, Gertrude Peterson, and Jerome Belinson
	JCO Jan 5 2000: 102. [Abstract] [Full Text] [PDF]
	Phase III Randomized Study of Cisplatin Versus Paclitaxel Versus Cisplatin and Paclitaxel in Patients With Suboptimal Stage III or IV Ovarian Cancer: A Gynecologic Oncology Group Study
	Franco M. Muggia, Patricia S. Braly, Mark F. Brady, Gregory Sutton, Theodore H. Niemann, Samuel L. Lentz, Ronald D. Alvarez, Paul R. Kucera, and James M. Small
	JCO Jan 5 2000: 106. [Abstract] [Full Text] [PDF]

GENITOURINARY CANCER
	Differential Expression of Nuclear Retinoid Receptors in Normal and Malignant Prostates
	Yair Lotan, Xiao C. Xu, Moshe Shalev, Reuben Lotan, Russell Williams, Thomas M. Wheeler, Timothy C. Thompson, and Dov Kadmon
	JCO Jan 1 2000: 116. [Abstract] [Full Text] [PDF]

LUNG CANCER
	Phase III Trial of Gemcitabine Plus Cisplatin Versus Cisplatin Alone in Patients With Locally Advanced or Metastatic Non–Small-Cell Lung Cancer
	A. B. Sandler, J. Nemunaitis, C. Denham, J. von Pawel, Y. Cormier, U. Gatzemeier, K. Mattson, Ch. Manegold, M. C. Palmer, A. Gregor, B. Nguyen, C. Niyikiza, and L. H. Einhorn
	JCO Jan 5 2000: 122. [Abstract] [Full Text] [PDF]
	Activity of Docetaxel in Platinum-Treated Non–Small-Cell Lung Cancer: Results of a Phase II Multicenter Trial
	David R. Gandara, Everett Vokes, Mark Green, Phillip Bonomi, Russell Devore, Robert Comis, David Carbone, Daniel Karp, and Chandra Belani
	JCO Jan 5 2000: 131. [Abstract] [Full Text] [PDF]
Case 1: Small Bowel Obstruction Due to Metastatic Lung Cancer
Matthew Galsky, Marla Darling, Jonathan Hecht, and Ravi Salgia
JCO Jan 5 2000: 227. [Full Text] [PDF]
Case 2: Acute Respiratory Failure Secondary to Lymphangitic Carcinomatosis
Namita Sood, Nicolas Bandarenko, and Linda J. Paradowski
JCO Jan 5 2000: 229. [Full Text]

GASTROINTESTINAL CANCER
	Phase III Multicenter Randomized Trial of Oxaliplatin Added to Chronomodulated Fluorouracil–Leucovorin as First-Line Treatment of Metastatic Colorectal Cancer
	S. Giacchetti, B. Perpoint, R. Zidani, N. Le Bail, R. Faggiuolo, C. Focan, P. Chollet, J. F. Llory, Y. Letourneau, B. Coudert, F. Bertheaut-Cvitkovic, D. Larregain-Fournier, A. Le Rol, S. Walter, R. Adam, J. L. Misset, and F. Lévi
	JCO Jan 5 2000: 136. [Abstract] [Full Text] [PDF]
	Adjuvant Active Specific Immunotherapy for Stage II and III Colon Cancer With an Autologous Tumor Cell Vaccine: Eastern Cooperative Oncology Group Study E5283
	Jules E. Harris, Louise Ryan, Herbert C. Hoover, Jr, Robert K. Stuart, Martin M. Oken, Al B. Benson, III, Edward Mansour, Daniel G. Haller, Judith Manola, and Michael G. Hanna, Jr
	JCO Jan 5 2000: 148. [Abstract] [Full Text] [PDF]

MELANOMA
	Randomized Phase III Study of Temozolomide Versus Dacarbazine in the Treatment of Patients With Advanced Metastatic Malignant Melanoma
	M. R. Middleton, J. J. Grob, N. Aaronson, G. Fierlbeck, W. Tilgen, S. Seiter, M. Gore, S. Aamdal, J. Cebon, A. Coates, B. Dreno, M. Henz, D. Schadendorf, A. Kapp, J. Weiss, U. Fraass, P. Statkevich, M. Muller, and N. Thatcher
	JCO Jan 5 2000: 158. [Abstract] [Full Text] [PDF]

PHASE I AND CLINICAL PHARMACOLOGY
	Phase I and Pharmacologic Study of PN401 and Fluorouracil in Patients With Advanced Solid Malignancies
	Manuel Hidalgo, Miguel A. Villalona-Calero, S. Gail Eckhardt, Ronald L. Drengler, Gladys Rodriguez, Lisa A. Hammond, Sami G. Diab, Geoffrey Weiss, Allison M. Garner, Elizabeth Campbell, Karen Davidson, Arthur Louie, James D. O’Neil, Reid von Borstel, Daniel D. Von Hoff, and Eric K. Rowinsky
	JCO Jan 5 2000: 167. [Abstract] [Full Text] [PDF]
	Phase I and Pharmacologic Study of the Specific Matrix Metalloproteinase Inhibitor BAY 12-9566 on a Protracted Oral Daily Dosing Schedule in Patients With Solid Malignancies
	Eric K. Rowinsky, Rachel Humphrey, Lisa A. Hammond, Cheryl Aylesworth, Leslie Smetzer, Manuel Hidalgo, Mark Morrow, Lon Smith, Allison Garner, J. Mel Sorensen, Daniel D. Von Hoff, and S. Gail Eckhardt
	JCO Jan 5 2000: 178. [Abstract] [Full Text] [PDF]
	Phase I Study of 3-Week Schedule of Irinotecan Combined With Cisplatin in Patients With Advanced Solid Tumors
	Maja J. A. de Jonge, Alex Sparreboom, André S. T. Planting, Maria E. L. van der Burg, Maureen M. de Boer-Dennert, Judith ter Steeg, Christian Jacques, and Jaap Verweij
	JCO Jan 5 2000: 187. [Abstract] [Full Text] [PDF]
	Pharmacokinetic, Metabolic, and Pharmacodynamic Profiles in a Dose-Escalating Study of Irinotecan and Cisplatin
	Maja J. A. de Jonge, Jaap Verweij, Peter de Bruijn, Eric Brouwer, Ron H. J. Mathijssen, Robbert J. van Alphen, Maureen M. de Boer-Dennert, Laurent Vernillet, Christian Jacques, and Alex Sparreboom
	JCO Jan 5 2000: 195. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Molecular Biology of the Ewing’s Sarcoma/Primitive Neuroectodermal Tumor Family
	Enrique de Alava and William L. Gerald
	JCO Jan 5 2000: 204. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	Waldenström’s Macroglobulinemia: Clinical Features, Complications, and Management
	Meletios A. Dimopoulos, Panayiotis Panayiotidis, Lia A. Moulopoulos, Petros Sfikakis, and Marinos Dalakas
	JCO Jan 5 2000: 214. [Abstract] [Full Text] [PDF]

ART OF ONCOLOGY

Caring for Dying Patients: What Is Right?

Mary Bretscher

JCO Jan 5 2000: 233. [Full Text] [PDF]

CORRESPONDENCE

Results From National Surgical Adjuvant Breast and Bowel Project Colon Cancer Trials

Harold O. Douglass, Jr

JCO Jan 5 2000: 235. [Full Text] [PDF]

More Patients Needed in Stage II Colon Cancer Trials

Jean-Pierre Pignon Michel Ducreux, Philippe Rougier, and Charles Erlichman

JCO Jan 5 2000: 235-a. [Full Text]

Chemoreduction for Retinoblastoma May Prevent Trilateral Retinoblastoma

Carol L. Shields Jerry A. Shields, Anna T. Meadows, and Tero Kivelä

JCO Jan 5 2000: 236. [Full Text]

Premedication for Irinotecan

Germano Zampa and Emanuela Magnolfi Antonia Borgomastro

JCO Jan 5 2000: 237. [Full Text]

SPECIAL DEPARTMENTS

ERRATA

Correction for vol. 17, p. 3426

JCO Jan 5 2000: 237-a. [Full Text]

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