BREAST CANCER
	Exemestane Is Superior to Megestrol Acetate After Tamoxifen Failure in Postmenopausal Women With Advanced Breast Cancer: Results of a Phase III Randomized Double-Blind Trial
	Manfred Kaufmann, Emilio Bajetta, Luc Yves Dirix, Luis Enrique Fein, Stephen E. Jones, Nicoletta Zilembo, Jean-Louis Dugardyn, Cristina Nasurdi, Robert G. Mennel, Jozica Cervek, Camilla Fowst, Anna Polli, Enrico di Salle, Alexei Arkhipov, Gabriella Piscitelli, Langdon L. Miller, and Giorgio Massimini
	JCO Apr 7 2000: 1399–1411. [Abstract] [Full Text] [PDF]
	Burdens and Benefits of Adjuvant Cyclophosphamide, Methotrexate, and Fluorouracil and Tamoxifen for Elderly Patients With Breast Cancer: The International Breast Cancer Study Group Trial VII
	Diana Crivellari, Marco Bonetti, Monica Castiglione-Gertsch, Richard D. Gelber, Carl-Magnus Rudenstam, Beat Thürlimann, Karen N. Price, Alan S. Coates, Christoph Hürny, Jürg Bernhard, Jurij Lindtner, John Collins, Hans-Jörg Senn, Franco Cavalli, John Forbes, Anne Gudgeon, Edda Simoncini, Hernan Cortes-Funes, Andrea Veronesi, Martin Fey, and Aron Goldhirsch
	JCO Apr 7 2000: 1412–1422. [Abstract] [Full Text] [PDF]
	Correlation of Vascular Endothelial Growth Factor Content With Recurrences, Survival, and First Relapse Site in Primary Node-Positive Breast Carcinoma After Adjuvant Treatment
	Barbro Linderholm, Kjell Grankvist, Nils Wilking, Mikael Johansson, Björn Tavelin, and Roger Henriksson
	JCO Apr 7 2000: 1423–1431. [Abstract] [Full Text] [PDF]
	Response of Circulating Tumor Cells to Systemic Therapy in Patients With Metastatic Breast Cancer: Comparison of Quantitative Polymerase Chain Reaction and Immunocytochemical Techniques
	Brendan M. Smith, Martin J. Slade, Jacqueline English, Helen Graham, Margreet Lüchtenborg, H. Dudley Sinnett, Nicholas C. P. Cross, and R. Charles Coombes
	JCO Apr 7 2000: 1432–1439. [Abstract] [Full Text] [PDF]

GENITOURINARY CANCER
	Suramin Therapy for Patients With Symptomatic Hormone-Refractory Prostate Cancer: Results of a Randomized Phase III Trial Comparing Suramin Plus Hydrocortisone to Placebo Plus Hydrocortisone
	Eric J. Small, Mark Meyer, M. Ernest Marshall, Leonard M. Reyno, Frederick J. Meyers, Ronald B. Natale, Peter F. Lenehan, Liang Chen, William J. Slichenmyer, and Mario Eisenberger
	JCO Apr 7 2000: 1440–1450. [Abstract] [Full Text] [PDF]

LUNG CANCER
	Randomized Trial Comparing Cisplatin, Gemcitabine, and Vinorelbine With Either Cisplatin and Gemcitabine or Cisplatin and Vinorelbine in Advanced Non–Small-Cell Lung Cancer: Interim Analysis of a Phase III Trial of the Southern Italy Cooperative Oncology Group
	Pasquale Comella, Giuseppe Frasci, Nicola Panza, Luigi Manzione, Giuseppe De Cataldis, Riccardo Cioffi, Luigi Maiorino, Enrico Micillo, Vito Lorusso, Gaetano Di Rienzo, Gianfranco Filippelli, Alfredo Lamberti, Michele Natale, Domenico Bilancia, Gianpaolo Nicolella, Angelo Di Nota, and Giuseppe Comella
	JCO Apr 7 2000: 1451–1457. [Abstract] [Full Text] [PDF]

HEAD AND NECK CANCER
	Hyperfractionated Radiation Therapy With or Without Concurrent Low-Dose Daily Cisplatin in Locally Advanced Squamous Cell Carcinoma of the Head and Neck: A Prospective Randomized Trial
	Branislav Jeremic, Yuta Shibamoto, Biljana Milicic, Nebojsa Nikolic, Aleksandar Dagovic, Jasna Aleksandrovic, Zeljko Vaskovic, and Ljiljana Tadic
	JCO Apr 7 2000: 1458–1464. [Abstract] [Full Text] [PDF]
	p53 Alterations Predict Tumor Response to Neoadjuvant Chemotherapy in Head and Neck Squamous Cell Carcinoma: A Prospective Series
	Arnauld Cabelguenne, Hélène Blons, Isabelle de Waziers, Françoise Carnot, Anne-Marie Houllier, Thierry Soussi, Daniel Brasnu, Phillipe Beaune, Ollivier Laccourreye, and Pierre Laurent-Puig
	JCO Apr 7 2000: 1465–1473. [Abstract] [Full Text] [PDF]

MELANOMA
	Post Hoc Economic Analysis of Temozolomide Versus Dacarbazine in the Treatment of Advanced Metastatic Melanoma
	Bruce E. Hillner, Sanjiv Agarwala, and Mark R. Middleton
	JCO Apr 7 2000: 1474–1480. [Abstract] [Full Text] [PDF]

BRAIN TUMORS
	Health-Related Quality of Life in Patients Treated With Temozolomide Versus Procarbazine for Recurrent Glioblastoma Multiforme
	D. Osoba, M. Brada, W. K. A. Yung, and M. Prados
	JCO Apr 7 2000: 1481–1491. [Abstract] [Full Text] [PDF]

PEDIATRIC ONCOLOGY
	Second Malignant Neoplasms After Treatment for Hodgkin’s Disease in Childhood or Adolescence
	Daniel M. Green, Andrew Hyland, Maurice P. Barcos, Julie A. Reynolds, R. Jeffrey Lee, Brenda C. Hall, and Michael A. Zevon
	JCO Apr 7 2000: 1492–1499. [Abstract] [Full Text] [PDF]
	Localized Childhood Hodgkin’s Disease: Response-Adapted Chemotherapy With Etoposide, Bleomycin, Vinblastine, and Prednisone Before Low-Dose Radiation Therapy—Results of the French Society of Pediatric Oncology Study MDH90
	J. Landman-Parker, H. Pacquement, T. Leblanc, J. L. Habrand, M. J. Terrier-Lacombe, Y. Bertrand, Y. Perel, A. Robert, C. Coze, I. Thuret, J. Donadieu, G. Schaison, G. Leverger, J. Lemerle, and O. Oberlin
	JCO Apr 7 2000: 1500–1507. [Abstract] [Full Text] [PDF]
	Six Months of Maintenance Chemotherapy After Intensified Treatment for Acute Lymphoblastic Leukemia of Childhood
	Yasunori Toyoda, Atsushi Manabe, Masahiro Tsuchida, Ryohji Hanada, Koichiro Ikuta, Yuri Okimoto, Akira Ohara, Yohji Ohkawa, Taijiroh Mori, Kohichi Ishimoto, Takeyuki Sato, Takashi Kaneko, Miho Maeda, Ken-ichi Koike, Toshiji Shitara, Yasutaka Hoshi, Ryohta Hosoya, Yukiko Tsunematsu, Fumio Bessho, Shinpei Nakazawa, and Tomohiro Saito
	JCO Apr 7 2000: 1508–1516. [Abstract] [Full Text] [PDF]
	Use of Recombinant Human Granulocyte Colony-Stimulating Factor to Increase Chemotherapy Dose-Intensity: A Randomized Trial in Very High-Risk Childhood Acute Lymphoblastic Leukemia
	G. Michel, J. Landman-Parker, M. F. Auclerc, C. Mathey, T. Leblanc, E. Legall, P. Bordigoni, J. P. Lamagnere, F. Demeocq, Y. Perel, A. Auvrignon, C. Berthou, F. Bauduer, B. Pautard, P. Schneider, G. Schaison, G. Leverger, and A. Baruchel
	JCO Apr 7 2000: 1517–1524. [Abstract] [Full Text] [PDF]
	Hypersensitivity or Development of Antibodies to Asparaginase Does Not Impact Treatment Outcome of Childhood Acute Lymphoblastic Leukemia
	Michael H. Woo, Lawrence J. Hak, Michael C. Storm, John T. Sandlund, Raul C. Ribeiro, Gaston K. Rivera, Jeffrey E. Rubnitz, Patricia L. Harrison, Bo Wang, William E. Evans, Ching-Hon Pui, and Mary V. Relling
	JCO Apr 7 2000: 1525–1532. [Abstract] [Full Text] [PDF]

HEMATOLOGIC MALIGNANCIES
	Fluorescence In Situ Hybridization on Peripheral-Blood Specimens Is a Reliable Method to Evaluate Cytogenetic Response in Chronic Myeloid Leukemia
	Steven Le Gouill, Pascaline Talmant, Noël Milpied, Axelle Daviet, Michèle Ancelot, Philippe Moreau, Jean-Luc Harousseau, Régis Bataille, and Hervé Avet-Loiseau
	JCO Apr 7 2000: 1533–1538. [Abstract] [Full Text] [PDF]
	Longitudinal Study of Adaptation to the Stress of Bone Marrow Transplantation
	Betsy L. Fife, Gertrude A. Huster, Kenneth G. Cornetta, Victoria N. Kennedy, Luke P. Akard, and E. Randolph Broun
	JCO Apr 7 2000: 1539–1549. [Abstract] [Full Text] [PDF]

SARCOMAS
	Vinorelbine Is an Effective and Safe Drug for AIDS-Related Kaposi’s Sarcoma: Results of a Phase II Study
	Guglielmo Nasti, Domenico Errante, Renato Talamini, Giuliano Rizzardini, Marco Fasan, Giuseppe Landonio, Claudia Zeroli, Guido Chichino, Ezio Nigra, Emanuela Vaccher, and Umberto Tirelli
	JCO Apr 7 2000: 1550–1557. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	Primary Systemic Therapy in Operable Breast Cancer
	Antonio C. Wolff and Nancy E. Davidson
	JCO Apr 7 2000: 1558–1569. [Abstract] [Full Text] [PDF]
	Osteoporosis Due to Cancer Treatment: Pathogenesis and Management
	Johannes Pfeilschifter and Ingo J. Diel
	JCO Apr 7 2000: 1570–1593. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Case 1: Hypoglycemic Syncope Due to a Peripheral Neuroectodermal Tumor

Klaus Empen, Carsten Otto, Josef Müller-Höcker, Jürgen Zapf, and Peter Schwandt

JCO Apr 7 2000: 1594–1596. [Full Text] [PDF]

Case 2: Myocardial Metastases Froma Carcinoid Tumor

Melitta Penz, Amir Kurtaran, Friedrich Vorbeck, Georg Oberhuber, and Markus Raderer

JCO Apr 7 2000: 1596–1597. [Full Text] [PDF]

ART OF ONCOLOGY

Interventional Pain Therapy for Intractable Abdominal Cancer Pain

David P. Seamans, Gilbert Y. Wong, and Jack L. Wilson

JCO Apr 7 2000: 1598–1600. [Full Text] [PDF]

CORRESPONDENCE

Predictors of Response to Chemotherapy

K. Mokbel, A. C. A. Leris, J. Chang, T. J. Powles, D. C. Allred, S. E. Ashley, G. M. Clark, and M. Dowsett

JCO Apr 7 2000: 1601–1602. [Full Text] [PDF]

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