EDITORIALS

Preoperative Chemoradiotherapy for Esophageal Cancer

David Kelsen

JCO Jan 15 2001: 283–285. [Full Text] [PDF]

Markers, Markers Everywhere . . . . . Prognosis in Colorectal Cancer—Time for a New Approach

Jervoise Andreyev and David Cunningham

JCO Jan 15 2001: 286–288. [Full Text] [PDF]

RAPID PUBLICATIONS
	Phase II Trial of Intratumoral Administration of ONYX-015, a Replication-Selective Adenovirus, in Patients With Refractory Head and Neck Cancer
	J. Nemunaitis, F. Khuri, I. Ganly, J. Arseneau, M. Posner, E. Vokes, J. Kuhn, T. McCarty, S. Landers, A. Blackburn, L. Romel, B. Randlev, S. Kaye, and D. Kirn
	JCO Jan 15 2001: 289–298. [Abstract] [Full Text] [PDF]

ORIGINAL REPORTS
Gastrointestinal Cancer
	K-ras and p16 Aberrations Confer Poor Prognosis in Human Colorectal Cancer
	M. Esteller, S. González, R. A. Risques, E. Marcuello, R. Mangues, J. R. Germà, J. G. Herman, G. Capellà, and M. A. Peinado
	JCO Jan 15 2001: 299–304. [Abstract] [Full Text] [PDF]
	Randomized Trial of Preoperative Chemoradiation Versus Surgery Alone in Patients With Locoregional Esophageal Carcinoma
	Susan G. Urba, Mark B. Orringer, Andrew Turrisi, Mark Iannettoni, Arlene Forastiere, and Myla Strawderman
	JCO Jan 15 2001: 305–313. [Abstract] [Full Text] [PDF]

Breast Cancer
	Phase II Study of Docetaxel, Doxorubicin, and Cyclophosphamide as First-Line Chemotherapy for Metastatic Breast Cancer
	J. M. Nabholtz, J. R. Mackey, M. Smylie, A. Paterson, D. R. Noël, T. Al-Tweigeri, K. Tonkin, S. North, N. Azli, and A. Riva
	JCO Jan 15 2001: 314–321. [Abstract] [Full Text] [PDF]
	Adjuvant Tamoxifen: Predictors of Use, Side Effects, and Discontinuation in Older Women
	Serkalem Demissie, Rebecca A. Silliman, and Timothy L. Lash
	JCO Jan 15 2001: 322–328. [Abstract] [Full Text] [PDF]
	Response to Cyclophosphamide, Methotrexate, and Fluorouracil in Lymph Node–Positive Breast Cancer According to HER2 Overexpression and Other Tumor Biologic Variables
	Sylvie Ménard, Pinuccia Valagussa, Silvana Pilotti, Luca Gianni, Elia Biganzoli, Patrizia Boracchi, Gorana Tomasic, Patrizia Casalini, Ettore Marubini, Maria I. Colnaghi, Natale Cascinelli, and Gianni Bonadonna
	JCO Jan 15 2001: 329–335. [Abstract] [Full Text] [PDF]
	Efficacy of Docetaxel 60 mg/m2 in Patients With Metastatic Breast Cancer According to the Status of Anthracycline Resistance
	Masashi Ando, Toru Watanabe, Kazuhiro Nagata, Masaru Narabayashi, Isamu Adachi, and Noriyuki Katsumata
	JCO Jan 15 2001: 336–342. [Abstract] [Full Text] [PDF]
	Combined Tamoxifen and Luteinizing Hormone-Releasing Hormone (LHRH) Agonist Versus LHRH Agonist Alone in Premenopausal Advanced Breast Cancer: A Meta-Analysis of Four Randomized Trials
	J. G.M. Klijn, R.W. Blamey, F. Boccardo, T. Tominaga, L. Duchateau, and R. Sylvester
	JCO Jan 15 2001: 343–353. [Abstract] [Full Text] [PDF]
	HER-2/neu Analysis in Archival Tissue Samples of Human Breast Cancer: Comparison of Immunohistochemistry and Fluorescence In Situ Hybridization
	Annette Lebeau, Daniela Deimling, Christine Kaltz, Andrea Sendelhofert, Anette Iff, Beate Luthardt, Michael Untch, and Udo Löhrs
	JCO Jan 15 2001: 354–363. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Tamoxifen in the Treatment of Advanced or Recurrent Endometrial Carcinoma: A Gynecologic Oncology Group Study
	Tate Thigpen, Mark F. Brady, Howard D. Homesley, John T. Soper, and Jeffrey Bell
	JCO Jan 15 2001: 364–367. [Abstract] [Full Text] [PDF]
	Occult Tumor Cells in Bone Marrow of Patients With Locoregionally Restricted Ovarian Cancer Predict Early Distant Metastatic Relapse
	Stephan Braun, Christian Schindlbeck, Florian Hepp, Wolfgang Janni, Christina Kentenich, Gert Riethmüller, and Klaus Pantel
	JCO Jan 15 2001: 368–375. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Pivotal Phase III Trial of Two Dose Levels of Denileukin Diftitox for the Treatment of Cutaneous T-Cell Lymphoma
	Elise Olsen, Madeleine Duvic, Arthur Frankel, Youn Kim, Ann Martin, Eric Vonderheid, Brian Jegasothy, Gary Wood, Michael Gordon, Peter Heald, Allan Oseroff, Lauren Pinter-Brown, Glen Bowen, Timothy Kuzel, David Fivenson, Francine Foss, Michael Glode, Arturo Molina, Elizabeth Knobler, Stanford Stewart, Kevin Cooper, Seth Stevens, Fiona Craig, James Reuben, Patricia Bacha, and Jean Nichols
	JCO Jan 15 2001: 376–388. [Abstract] [Full Text] [PDF]
	Phase II Study of Rituximab in Combination With CHOP Chemotherapy in Patients With Previously Untreated, Aggressive Non-Hodgkin’s Lymphoma
	J. M. Vose, B. K. Link, M. L. Grossbard, M. Czuczman, A. Grillo-Lopez, P. Gilman, A. Lowe, L. A. Kunkel, and R. I. Fisher
	JCO Jan 15 2001: 389–397. [Abstract] [Full Text] [PDF]
	Primary Cutaneous Non-Hodgkin’s Lymphoma of Ann Arbor Stage I: Preferential Cutaneous Relapses but High Cure Rate With Doxorubicin-Based Therapy
	Andreas H. Sarris, Ira Braunschweig, L. Jeffrey Medeiros, Madeleine Duvic, Chul S. Ha, M. Alma Rodriguez, Frederick B. Hagemeister, Peter McLaughlin, Jorge Romaguera, James Cox, and Fernando Cabanillas
	JCO Jan 15 2001: 398–405. [Abstract] [Full Text] [PDF]
	Autologous Transplantation for Diffuse Aggressive Non-Hodgkin’s Lymphoma in Patients Never Achieving Remission: A Report from the Autologous Blood and Marrow Transplant Registry
	Julie M. Vose, Mei-Jie Zhang, Philip A. Rowlings, Hillard M. Lazarus, Brian J. Bolwell, Cesar O. Freytes, Santiago Pavlovsky, Armand Keating, Burhan Yanes, Koen van Besien, James O. Armitage, and Mary M. Horowitz
	JCO Jan 15 2001: 406–413. [Abstract] [Full Text] [PDF]
	Prognostic Value of Positron Emission Tomography (PET) With Fluorine-18 Fluorodeoxyglucose ([18F]FDG) After First-Line Chemotherapy in Non-Hodgkin’s Lymphoma: Is [18F]FDG-PET a Valid Alternative to Conventional Diagnostic Methods?
	Karoline Spaepen, Sigrid Stroobants, Patrick Dupont, Steven Van Steenweghen, José Thomas, Peter Vandenberghe, Lucien Vanuytsel, Guy Bormans, Jan Balzarini, Christine De Wolf-Peeters, Luc Mortelmans, and Gregor Verhoef
	JCO Jan 15 2001: 414–419. [Abstract] [Full Text] [PDF]
	Frequency of the Bcl-2/IgH Rearrangement in Normal Individuals: Implications for the Monitoring of Disease in Patients With Follicular Lymphoma
	Karin E. Summers, Lindsey K. Goff, A. Gerry Wilson, Rajnish K. Gupta, T. Andrew Lister, and Jude Fitzgibbon
	JCO Jan 15 2001: 420–424. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Interferon Adjuvant to Radical Nephrectomy in Robson Stages II and III Renal Cell Carcinoma: A Multicentric Randomized Study
	Giorgio Pizzocaro, Luigi Piva, Maria Colavita, Sonia Ferri, Raffaella Artusi, Patrizia Boracchi, Giorgio Parmiani, and Ettore Marubini
	JCO Jan 15 2001: 425–431. [Abstract] [Full Text] [PDF]

Lung Cancer
	Vascular Endothelial Growth Factor 189 mRNA Isoform Expression Specifically Correlates With Tumor Angiogenesis, Patient Survival, and Postoperative Relapse in Non–Small-Cell Lung Cancer
	Ang Yuan, Chong-Jen Yu, Sow-Hsong Kuo, Wen-Jone Chen, Fang-Yue Lin, Kwen-Tay Luh, Pan-Chyr Yang, and Yung-Chie Lee
	JCO Jan 15 2001: 432–441. [Abstract] [Full Text] [PDF]
	Twice-Weekly Paclitaxel and Weekly Carboplatin With Concurrent Thoracic Radiation Followed by Carboplatin/Paclitaxel Consolidation for Stage III Non–Small-Cell Lung Cancer: A California Cancer Consortium Phase II Trial
	Derick Lau, Bryan Leigh, David Gandara, Martin Edelman, Robert Morgan, Valerie Israel, Primo Lara, Richard Wilder, Janice Ryu, and James Doroshow
	JCO Jan 15 2001: 442–447. [Abstract] [Full Text] [PDF]
	Lack of Prognostic Significance of p53 and K-ras Mutations in Primary Resected Non–Small-Cell Lung Cancer on E4592: A Laboratory Ancillary Study on an Eastern Cooperative Oncology Group Prospective Randomized Trial of Postoperative Adjuvant Therapy
	Joan H. Schiller, Sudeshna Adak, Richard H. Feins, Steven M. Keller, Willard A. Fry, Robert B. Livingston, M. Elizabeth M. Hammond, Barbara Wolf, Linda Sabatini, James Jett, Leslie Kohman, and David H. Johnson
	JCO Jan 15 2001: 448–457. [Abstract] [Full Text] [PDF]
	Phase I/II Study of Escalating Doses of Vinorelbine in Combination With Oxaliplatin in Patients With Advanced Non–Small-Cell Lung Cancer
	Isabelle Monnet, Patrick Soulié, Hubert de Cremoux, Sabine Saltiel-Voisin, Mohammed Bekradda, Jean-Claude Saltiel, Etienne Brain, Ghislaine Dupont-André, and Esteban Cvitkovic
	JCO Jan 15 2001: 458–463. [Abstract] [Full Text] [PDF]

Bone Marrow Transplantation
	Solid Cancers After Bone Marrow Transplantation
	Smita Bhatia, Andrew D. Louie, Ravi Bhatia, Margaret R. O’Donnell, Henry Fung, Ashwin Kashyap, Amrita Krishnan, Arturo Molina, Auayporn Nademanee, Joyce C. Niland, Pablo A. Parker, David S. Snyder, Ricardo Spielberger, Anthony Stein, and Stephen J. Forman
	JCO Jan 15 2001: 464–471. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Risks of Young Age for Selected Neurocognitive Deficits in Medulloblastoma Are Associated With White Matter Loss
	Raymond K. Mulhern, Shawna L. Palmer, Wilburn E. Reddick, John O. Glass, Larry E. Kun, June Taylor, James Langston, and Amar Gajjar
	JCO Jan 15 2001: 472–479. [Abstract] [Full Text] [PDF]
	Growth Hormone Replacement Therapy in Children With Medulloblastoma: Use and Effect on Tumor Control
	Roger J. Packer, James M. Boyett, Anna J. Janss, Theodora Stavrou, Larry Kun, Jeffrey Wisoff, Carolyn Russo, Russell Geyer, Peter Phillips, Mark Kieran, Mark Greenberg, Stewart Goldman, Douglas Hyder, Richard Heideman, Dana Jones-Wallace, Gilbert P. August, Sharon H. Smith, and Thomas Moshang
	JCO Jan 15 2001: 480–487. [Abstract] [Full Text] [PDF]
	Optimal Duration of Preoperative Therapy in Unilateral and Nonmetastatic Wilms’ Tumor in Children Older Than 6 Months: Results of the Ninth International Society of Pediatric Oncology Wilms’ Tumor Trial and Study
	M. F. Tournade, C. Com-Nougué, J. de Kraker, R. Ludwig, A. Rey, J. M.B. Burgers, B. Sandstedt, J. Godzinski, M. Carli, R. Potter, and J. M. Zucker
	JCO Jan 15 2001: 488–500. [Abstract] [Full Text] [PDF]

Palliative Care
	Feasibility of Quantitative Pain Assessment in Outpatient Oncology Practice
	Deborah J. Rhodes, Rachel C. Koshy, William C. Waterfield, Albert W. Wu, and Stuart A. Grossman
	JCO Jan 15 2001: 501–508. [Abstract] [Full Text] [PDF]

Brain Tumors
	Randomized Trial of Procarbazine, Lomustine, and Vincristine in the Adjuvant Treatment of High-Grade Astrocytoma: A Medical Research Council Trial
	JCO Jan 15 2001: 509–518. [Abstract] [Full Text] [PDF]
	Phase I and Pharmacokinetic Study of Photodynamic Therapy for High-Grade Gliomas Using a Novel Boronated Porphyrin
	Mark A. Rosenthal, Bhadu Kavar, John S. Hill, Denis J. Morgan, Roger L. Nation, Stanley S. Stylli, Russell L. Basser, Shannon Uren, Howard Geldard, Michael D. Green, Stephen B. Kahl, and Andrew H. Kaye
	JCO Jan 15 2001: 519–524. [Abstract] [Full Text] [PDF]

Sarcomas
	Prognostic Factors in Localized Primary Synovial Sarcoma: A Multicenter Study of 128 Adult Patients
	Martine Trassard, Viviane Le Doussal, Kamel Hacène, Philippe Terrier, Dominique Ranchère, Louis Guillou, Maryse Fiche, Françoise Collin, Marie-Odile Vilain, Gérard Bertrand, Jocelyne Jacquemier, Xavier Sastre-Garau, Nguyen Binh Bui, Françoise Bonichon, and Jean-Michel Coindre
	JCO Jan 15 2001: 525–534. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Phase I Trial of Concurrent Tirapazamine, Cisplatin, and Radiotherapy in Patients With Advanced Head and Neck Cancer
	Danny Rischin, Lester Peters, Rodney Hicks, Peter Hughes, Richard Fisher, Rosetta Hart, Maree Sexton, Ieta D’Costa, and Reinhard von Roemeling
	JCO Jan 15 2001: 535–542. [Abstract] [Full Text] [PDF]

Radiation Oncology
	Can We Predict Radiation-Induced Changes in Pulmonary Function Based on the Sum of Predicted Regional Dysfunction?
	Ming Fan, Lawrence B. Marks, Donna Hollis, Gunilla G. Bentel, Mitchell S. Anscher, Gregory Sibley, R. Edward Coleman, Ronald J. Jaszczak, and Michael T. Munley
	JCO Jan 15 2001: 543–550. [Abstract] [Full Text] [PDF]

Cancer Related Complications
	Comparison of Diameter and Perimeter Methods for Tumor Volume Calculation
	A. Gregory Sorensen, Shveta Patel, Carla Harmath, Sarah Bridges, Jennifer Synnott, Amy Sievers, Young-Ho Yoon, E. John Lee, Michael C. Yang, Robert F. Lewis, Gordon J. Harris, Michael Lev, Pamela W. Schaefer, Bradley R. Buchbinder, Glenn Barest, Kei Yamada, John Ponzo, H. Young Kwon, Joseph Gemmete, Jeff Farkas, Andrew L. Tievsky, Richard B. Ziegler, Megan R.C. Salhus, and Robert Weisskoff
	JCO Jan 15 2001: 551–557. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Zoledronic Acid Is Superior to Pamidronate in the Treatment of Hypercalcemia of Malignancy: A Pooled Analysis of Two Randomized, Controlled Clinical Trials
	P. Major, A. Lortholary, J. Hon, E. Abdi, G. Mills, H. D. Menssen, F. Yunus, R. Bell, J. Body, E. Quebe-Fehling, and J. Seaman
	JCO Jan 15 2001: 558–567. [Abstract] [Full Text] [PDF]

Melanoma
	Melastatin Expression and Prognosis in Cutaneous Malignant Melanoma
	Lyn M. Duncan, James Deeds, Frank E. Cronin, Michael Donovan, Arthur J. Sober, Michael Kauffman, and Jeanette J. McCarthy
	JCO Jan 15 2001: 568–576. [Abstract] [Full Text] [PDF]
	Increased Serum Concentration of Angiogenic Factors in Malignant Melanoma Patients Correlates With Tumor Progression and Survival
	Selma Ugurel, Gunter Rappl, Wolfgang Tilgen, and Uwe Reinhold
	JCO Jan 15 2001: 577–583. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I Clinical Trial of Oral COL-3, a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer
	Michelle A. Rudek, William D. Figg, Valerie Dyer, William Dahut, Maria L. Turner, Seth M. Steinberg, David J. Liewehr, David R. Kohler, James M. Pluda, and Eddie Reed
	JCO Jan 15 2001: 584–592. [Abstract] [Full Text] [PDF]

SPECIAL DEPARTMENTS

CORRESPONDENCE

Blinding of Clinical Investigators

R. P. Abratt

JCO Jan 15 2001: 593. [Full Text] [PDF]

Ascertainment of the Incidence of Beckwith-Wiedemann Syndrome in the National Wilms Tumor Study Group

Richard Grundy, Jon Pritchard, and Lisa Diller

JCO Jan 15 2001: 593-a–594. [Full Text] [PDF]

Hazards of Quality-of-Life Data for Clinical Decision Making

Mark Somerfield, Aminah Jatoi, Phuong L. Nguyen, Shaji Kumar, Jeff Sloan, and Charles L. Loprinzi

JCO Jan 15 2001: 594–595. [Full Text] [PDF]

When the Tumor is Not the Target, Tell the Children

Ruprecht Nitschke, William H. Meyer, and Heather C. Huszti

JCO Jan 15 2001: 595–596. [Full Text] [PDF]

Conflicting Phase II Efficacy Data for Doxil

Gregory Frykman, Grant Williams, Richard Pazdur, and Alan N. Gordon

JCO Jan 15 2001: 596–597. [Full Text] [PDF]

Bleomycin-Induced Lung Toxicity and Pentoxifylline

John Goffin, Harvey Kreisman, and Victor Sandor

JCO Jan 15 2001: 597–598. [Full Text] [PDF]

Complemenary Therapies in Cancer Patients

Leonard R. Prosnitz

JCO Jan 15 2001: 598. [Full Text] [PDF]

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