EDITORIALS

Prostate Cancer: The Price of Early Detection

Patricia A. Ganz and Mark S. Litwin

JCO Mar 15 2001: 1587–1588. [Full Text] [PDF]

ORIGINAL REPORTS
Hematologic Malignancies
	Phase I/II Study of the P-Glycoprotein Modulator PSC 833 in Patients With Acute Myeloid Leukemia
	R. Dorr, C. Karanes, C. Spier, T. Grogan, J. Greer, J. Moore, B. Weinberger, G. Schiller, T. Pearce, M. Litchman, W. Dalton, D. Roe, and A. F. List
	JCO Mar 15 2001: 1589–1599. [Abstract] [Full Text] [PDF]
	Long-Term Persistence of Monoclonal B Cells After Cure of Helicobacter pylori Infection and Complete Histologic Remission in Gastric Mucosa–Associated Lymphoid Tissue B-Cell Lymphoma
	Christian Thiede, Thomas Wündisch, Birgit Alpen, Beatrix Neubauer, Andrea Morgner, Marc Schmitz, Gerhard Ehninger, Manfred Stolte, Ekkehard Bayerdörffer, and Andreas Neubauer
	JCO Mar 15 2001: 1600–1609. [Abstract] [Full Text] [PDF]
	Lung Cancer After Hodgkin’s Disease: A Nested Case-Control Study of the Relation to Treatment
	A. J. Swerdlow, M. J. Schoemaker, R. Allerton, A. Horwich, J. A. Barber, D. Cunningham, T. A. Lister, A. Z.S. Rohatiner, G. Vaughan Hudson, M. V. Williams, and D. C. Linch
	JCO Mar 15 2001: 1610–1618. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Health-Related Quality-of-Life Effects of Radical Prostatectomy and Primary Radiotherapy for Screen-Detected or Clinically Diagnosed Localized Prostate Cancer
	Joanna B. Madalinska, Marie-Louise Essink-Bot, Harry J. de Koning, Wim J. Kirkels, Paul J. van der Maas, and Fritz H. Schröder
	JCO Mar 15 2001: 1619–1628. [Abstract] [Full Text] [PDF]
	Equivalence of Three or Four Cycles of Bleomycin, Etoposide, and Cisplatin Chemotherapy and of a 3- or 5-Day Schedule in Good-Prognosis Germ Cell Cancer: A Randomized Study of the European Organization for Research and Treatment of Cancer Genitourinary Tract Cancer Cooperative Group and the Medical Research Council
	Ronald de Wit, J. Trevor Roberts, Peter M. Wilkinson, Pieter H.M. de Mulder, Graham M. Mead, Sophie D. Fosså, Pat Cook, Linda de Prijck, Sally Stenning, and Laurence Collette
	JCO Mar 15 2001: 1629–1640. [Abstract] [Full Text] [PDF]
	Second-Line Chemotherapy in Patients With Relapsed Extragonadal Nonseminomatous Germ Cell Tumors: Results of an International Multicenter Analysis
	Jörg T. Hartmann, Lawrence Einhorn, Craig R. Nichols, Jean-P. Droz, Alan Horwich, Arthur Gerl, Sophie D. Fossa, Jörg Beyer, Jörg Pont, Hans-J. Schmoll, Lothar Kanz, and Carsten Bokemeyer
	JCO Mar 15 2001: 1641–1648. [Abstract] [Full Text] [PDF]
	Improved Prognostication of Renal Cell Carcinoma Using an Integrated Staging System
	Amnon Zisman, Allan J. Pantuck, Fredrick Dorey, Jonathan W. Said, Oleg Shvarts, Deanna Quintana, Barbara J. Gitlitz, Jean B. deKernion, Robert A. Figlin, and Arie S. Belldegrun
	JCO Mar 15 2001: 1649–1657. [Abstract] [Full Text] [PDF]

Cancer Prevention
	Recommendations for Cancer Prevention Trials Using Potentially Ototoxic Test Agents
	Lawrence I. Shotland, Frank G. Ondrey, Kristen A. Mayo, and Jaye L. Viner
	JCO Mar 15 2001: 1658–1663. [Abstract] [Full Text] [PDF]

Breast Cancer
	Safety of the Synthetic Retinoid Fenretinide: Long-Term Results From a Controlled Clinical Trial for the Prevention of Contralateral Breast Cancer
	Tiziana Camerini, Luigi Mariani, Giuseppe De Palo, Ettore Marubini, Maria Gaetana Di Mauro, Andrea Decensi, Alberto Costa, and Umberto Veronesi
	JCO Mar 15 2001: 1664–1670. [Abstract] [Full Text] [PDF]
	Effect of Pregnancy on Overall Survival After the Diagnosis of Early-Stage Breast Cancer
	Shari Gelber, Alan S. Coates, Aron Goldhirsch, Monica Castiglione-Gertsch, Gianluigi Marini, Jurij Lindtner, David Z. Edelmann, Anne Gudgeon, Vernon Harvey, and Richard D. Gelber
	JCO Mar 15 2001: 1671–1675. [Abstract] [Full Text] [PDF]
	Decision Support for Patients With Early-Stage Breast Cancer: Effects of an Interactive Breast Cancer CDROM on Treatment Decision, Satisfaction, and Quality of Life
	Sjaak Molenaar, Mirjam AG Sprangers, Emiel J. Th. Rutgers, Ernest JT Luiten, Jan Mulder, Patrick MM Bossuyt, Jannes JE van Everdingen, Paul Oosterveld, and Hanneke CJM de Haes
	JCO Mar 15 2001: 1676–1687. [Abstract] [Full Text] [PDF]
	Differences in Risk Factors for Local and Distant Recurrence After Breast-Conserving Therapy or Mastectomy for Stage I and II Breast Cancer: Pooled Results of Two Large European Randomized Trials
	Adri C. Voogd, Maja Nielsen, Johannes L. Peterse, Mogens Blichert-Toft, Harry Bartelink, Marie Overgaard, Geertjan van Tienhoven, Knud West Andersen, Richard J. Sylvester, and Joop A. van Dongen
	JCO Mar 15 2001: 1688–1697. [Abstract] [Full Text] [PDF]
	Comparison of Methods of Measuring HER-2 in Metastatic Breast Cancer Patients Treated With High-Dose Chemotherapy
	Lyndsay N. Harris, Vlayka Liotcheva, Gloria Broadwater, Michael J. Ramirez, Peter Maimonis, Steven Anderson, Tajuana Everett, David Harpole, Mary Beth Moore, Donald A. Berry, David Rizzeri, James J. Vredenburgh, and Rex C. Bentley
	JCO Mar 15 2001: 1698–1706. [Abstract] [Full Text] [PDF]
	Doxorubicin and Paclitaxel Versus Fluorouracil, Doxorubicin, and Cyclophosphamide as First-Line Therapy for Women With Metastatic Breast Cancer: Final Results of a Randomized Phase III Multicenter Trial
	Jacek Jassem, Tadeusz Pienkowski, Anna Pluzanska, Svetislav Jelic, Vera Gorbunova, Zrinka Mrsic-Krmpotic, Juris Berzins, Tomas Nagykalnai, Nelly Wigler, Josette Renard, Stephane Munier, and Catherine Weil
	JCO Mar 15 2001: 1707–1715. [Abstract] [Full Text] [PDF]
	Phase I Study of Stealth Liposomal Doxorubicin in Combination With Gemcitabine in the Treatment of Patients With Metastatic Breast Cancer
	Edgardo Rivera, Vicente Valero, Laura Syrewicz, Zia Rahman, Francisco L. Esteva, Richard L. Theriault, Marguerite M. Rosales, Daniel Booser, James L. Murray, Robert C. Bast, Jr, and Gabriel N. Hortobagyi
	JCO Mar 15 2001: 1716–1722. [Abstract] [Full Text] [PDF]

Melanoma
	Interlaboratory Evaluation of a New Reverse Transcriptase Polymerase Chain Reaction–Based Enzyme-Linked Immunosorbent Assay for the Detection of Circulating Melanoma Cells: A Multicenter Study of the Dermatologic Cooperative Oncology Group
	U. Reinhold, C. Berkin, A.-K. Bosserhoff, A. Deutschmann, C. Garbe, R. Gläser, R. Hein, G. Krähn, R. U. Peter, G. Rappl, B. Schittek, S. Seiter, S. Ugurel, M. Volkenandt, and W. Tilgen
	JCO Mar 15 2001: 1723–1727. [Abstract] [Full Text] [PDF]

Clinical Trials
	Prospective Evaluation of Cancer Clinical Trial Accrual Patterns: Identifying Potential Barriers to Enrollment
	Primo N. Lara, Jr, Roger Higdon, Nelson Lim, Karen Kwan, Michael Tanaka, Derick H.M. Lau, Ted Wun, Jeanna Welborn, Frederick J. Meyers, Scott Christensen, Robert O’Donnell, Carol Richman, Sidney A. Scudder, Joseph Tuscano, David R. Gandara, and Kit S. Lam
	JCO Mar 15 2001: 1728–1733. [Abstract] [Full Text] [PDF]
	Prevention of Cisplatin-Induced Emesis by the Oral Neurokinin-1 Antagonist, MK-869, in Combination With Granisetron and Dexamethasone or With Dexamethasone Alone
	Daniel Campos, Jose Rodrigues Pereira, Rick R. Reinhardt, Carlos Carracedo, Sergio Poli, Conrado Vogel, Jorge Martinez-Cedillo, Aura Erazo, Johanna Wittreich, Lars-Olof Eriksson, Alexandra D. Carides, and Barry J. Gertz
	JCO Mar 15 2001: 1759–1767. [Abstract] [Full Text] [PDF]
	Discussing Adjuvant Cancer Therapy
	Natasha Leighl, Melina Gattellari, Phyllis Butow, Richard Brown, and Martin H.N. Tattersall
	JCO Mar 15 2001: 1768–1778. [Abstract] [Full Text] [PDF]

Lung Cancer
	Twenty-Two Years of Phase III Trials for Patients With Advanced Non–Small-Cell Lung Cancer: Sobering Results
	Oscar S. Breathnach, Boris Freidlin, Barbara Conley, Mark R. Green, David H. Johnson, David R. Gandara, Michael O’Connell, Frances A. Shepherd, and Bruce E. Johnson
	JCO Mar 15 2001: 1734–1742. [Abstract] [Full Text] [PDF]
	Phase II Comparator Study of Oral Versus Intravenous Topotecan in Patients With Chemosensitive Small-Cell Lung Cancer
	Joachim von Pawel, Ulrich Gatzemeier, Jean-Louis Pujol, Lionel Moreau, S. Bildat, Malcolm Ranson, Gary Richardson, Claus Steppert, Alain Rivière, Ina Camlett, Stephen Lane, and Graham Ross
	JCO Mar 15 2001: 1743–1749. [Abstract] [Full Text] [PDF]
	Adenovirus-Mediated Wild-Type p53 Gene Transfer in Patients Receiving Chemotherapy for Advanced Non–Small-Cell Lung Cancer: Results of a Multicenter Phase II Study
	Martin Schuler, Richard Herrmann, Jacques L.P. De Greve, A. Keith Stewart, Ulrich Gatzemeier, David J. Stewart, Leslie Laufman, Richard Gralla, Jürgen Kuball, Roland Buhl, Claus P. Heussel, Friedrich Kommoss, André P. Perruchoud, Frances A. Shepherd, Mary Ann Fritz, Jo Ann Horowitz, Christoph Huber, and Christoph Rochlitz
	JCO Mar 15 2001: 1750–1758. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Polymorphisms of the Repeated Sequences in the Enhancer Region of the Thymidylate Synthase Gene Promoter May Predict Downstaging After Preoperative Chemoradiation in Rectal Cancer
	Elena Villafranca, Yury Okruzhnov, Miguel A. Dominguez, Jesús García-Foncillas, Ignacio Azinovic, Enrique Martínez, Jose J. Illarramendi, Fernando Arias, Rafael Martínez-Monge, Esteban Salgado, Silvia Angeletti, and Antonio Brugarolas
	JCO Mar 15 2001: 1779–1786. [Abstract] [Full Text] [PDF]
	Fluorouracil Plus Leucovorin as Effective Adjuvant Chemotherapy in Curatively Resected Stage III Colon Cancer: Results of the Trial adjCCA-01
	Rainer Porschen, Andreas Bermann, Thomas Löffler, Gregor Haack, Klaus Rettig, Yvonne Anger, and Georg Strohmeyer
	JCO Mar 15 2001: 1787–1794. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Circulating Neuroblastoma Cells Detected by Reverse Transcriptase Polymerase Chain Reaction for Tyrosine Hydroxylase mRNA Are an Independent Poor Prognostic Indicator in Stage 4 Neuroblastoma in Children Over 1 Year
	Susan A. Burchill, Ian J. Lewis, Keith R. Abrams, Richard Riley, John Imeson, Andrew D.J. Pearson, Ross Pinkerton, and Peter Selby
	JCO Mar 15 2001: 1795–1801. [Abstract] [Full Text] [PDF]
	Immediate Neurocognitive Effects of Methylphenidate on Learning-Impaired Survivors of Childhood Cancer
	Stephen J. Thompson, Laurie Leigh, Robbin Christensen, Xiaoping Xiong, Larry E. Kun, Richard L. Heideman, W. Eugene Reddick, Amar Gajjar, Thomas Merchant, Ching-Hon Pui, Melissa M. Hudson, and Raymond K. Mulhern
	JCO Mar 15 2001: 1802–1808. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Reliability and Validity of the Functional Assessment of Cancer Therapy–Ovarian
	Karen Basen-Engquist, Diane Bodurka-Bevers, Mary A. Fitzgerald, Kimberly Webster, David Cella, Shaohua Hu, and David M. Gershenson
	JCO Mar 15 2001: 1809–1817. [Abstract] [Full Text] [PDF]

Sarcomas
	Localized Ewing Tumor of Bone: Final Results of the Cooperative Ewing’s Sarcoma Study CESS 86
	M. Paulussen, S. Ahrens, J. Dunst, W. Winkelmann, G.U. Exner, R. Kotz, G. Amann, B. Dockhorn-Dworniczak, D. Harms, S. Müller-Weihrich, K. Welte, B. Kornhuber, G. Janka-Schaub, U. Göbel, J. Treuner, P.A. Voûte, A. Zoubek, H. Gadner, and H. Jürgens
	JCO Mar 15 2001: 1818–1829. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I Trial of Oral Green Tea Extract in Adult Patients With Solid Tumors
	Katherine M.W. Pisters, Robert A. Newman, Brenda Coldman, Dong M. Shin, Fadlo R. Khuri, Waun Ki Hong, Bonnie S. Glisson, and Jin S. Lee
	JCO Mar 15 2001: 1830–1838. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	Development of Inhalational Agents for Oncologic Use
	Sunil Sharma, Dorothy White, Anthony R. Imondi, Michael E. Placke, David M. Vail, and Mark G. Kris
	JCO Mar 15 2001: 1839–1847. [Abstract] [Full Text] [PDF]
	Clinical Trial Designs for the Early Clinical Development of Therapeutic Cancer Vaccines
	Richard M. Simon, Seth M. Steinberg, Michael Hamilton, Allan Hildesheim, Samir Khleif, Larry W. Kwak, Crystal L. Mackall, Jeffrey Schlom, Suzanne L. Topalian, and Jay A. Berzofsky
	JCO Mar 15 2001: 1848–1854. [Abstract] [Full Text] [PDF]
	Primary Mediastinal B-Cell Lymphoma: A Review of Pathology and Management
	Koen van Besien, Mohammed Kelta, and Pranay Bahaguna
	JCO Mar 15 2001: 1855–1864. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLES
	2000 Update of Recommendations for the Use of Tumor Markers in Breast and Colorectal Cancer: Clinical Practice Guidelines of the American Society of Clinical Oncology
	Robert C. Bast, Jr, Peter Ravdin, Daniel F. Hayes, Susan Bates, Herbert Fritsche, Jr, John M. Jessup, Nancy Kemeny, Gershon Y. Locker, Robert G. Mennel, and Mark R. Somerfield
	JCO Mar 15 2001: 1865–1878. [Abstract] [Full Text] [PDF]

SPECIAL DEPARTMENTS

CORRESPONDENCE

Postoperative Adjuvant Chemoradiation Therapy for Patients With Resected Gastric Cancer: Intergroup 116

Roderich E. Schwarz and David P. Kelsen

JCO Mar 15 2001: 1879–1880. [Full Text] [PDF]

Preoperative Chemoradiotherapy Using Taxanes for Locally Advanced Esophageal Carcinoma

Pierre Thirion, Youri Piedbois, and David J. Adelstein

JCO Mar 15 2001: 1880–1882. [Full Text]

Safety of Sentinel Lymph Node Dissection and Significance of Cytokeratin Micrometastases

Robert J. Rosser, Armando Giuliano, and Kelly McMasters

JCO Mar 15 2001: 1882–1883. [Full Text]

Survival Benefit of High-Dose Therapy in Poor-Risk Aggressive Non-Hodgkin’s Lymphoma: Concerns About Omissions in the Data Presented

R.D. Kennedy, R.G. Cuthbert, P.J. Kettle, and T.C.M. Morris

JCO Mar 15 2001: 1884. [Full Text]

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