EDITORIALS

Are All Hypotheses Generated Before Data Analysis Prospective?

Walter J. Urba and W. Gregory Alvord

JCO Mar 15 2002: 1431–1433. [Full Text] [PDF]

Dear Doctor: We Really Are Not Sure What Dose of Capecitabine You Should Prescribe for Your Patient

Mark J. Ratain

JCO Mar 15 2002: 1434–1435. [Full Text] [PDF]

Cooling Off Hot Flashes

Vered Stearns and Daniel F. Hayes

JCO Mar 15 2002: 1436–1438. [Full Text] [PDF]

Vive La Difference: Sex and Fluorouracil Toxicity

John S. Macdonald

JCO Mar 15 2002: 1439–1441. [Full Text] [PDF]

Liver Metastases From Colorectal Cancer: The Turning Point

Bernard Nordlinger and Philippe Rougier

JCO Mar 15 2002: 1442–1445. [Full Text] [PDF]

Unexpected Serious Toxicity With Chemotherapy and Antiangiogenic Combinations: Time to Take Stock!

Gavin M. Marx, Christopher B. Steer, Peter Harper, Nick Pavlakis, Olivier Rixe, and David Khayat

JCO Mar 15 2002: 1446–1448. [Full Text] [PDF]

ORIGINAL REPORTS
Breast Cancer
	Effect of Soy Phytoestrogens on Hot Flashes in Postmenopausal Women With Breast Cancer: A Randomized, Controlled Clinical Trial
	Cheri L. Van Patten, Ivo A. Olivotto, G. Keith Chambers, Karen A. Gelmon, T. Gregory Hislop, Edith Templeton, Angela Wattie, and Jerilynn C. Prior
	JCO Mar 15 2002: 1449–1455. [Abstract] [Full Text] [PDF]
	Neoadjuvant Chemotherapy in Breast Cancer: Significantly Enhanced Response With Docetaxel
	Ian C. Smith, Steven D. Heys, Andrew W. Hutcheon, Iain D. Miller, Simon Payne, Fiona J. Gilbert, Antoinne K. Ah-See, Oleg Eremin, Leslie G. Walker, Tarun K. Sarkar, S. Peter Eggleton, and Keith N. Ogston
	JCO Mar 15 2002: 1456–1466. [Abstract] [Full Text] [PDF]
	Elevated Serum HER-2/neu Level Predicts Decreased Response to Hormone Therapy in Metastatic Breast Cancer
	Allan Lipton, S.M. Ali, K. Leitzel, L. Demers, V. Chinchilli, L. Engle, Harold A. Harvey, C. Brady, C.M. Nalin, M. Dugan, W. Carney, and J. Allard
	JCO Mar 15 2002: 1467–1472. [Abstract] [Full Text] [PDF]
	Treatment Decision Making in Early-Stage Breast Cancer: Should Surgeons Match Patients’ Desired Level of Involvement?
	Nancy L. Keating, Edward Guadagnoli, Mary Beth Landrum, Catherine Borbas, and Jane C. Weeks
	JCO Mar 15 2002: 1473–1479. [Abstract] [Full Text] [PDF]
	Clinical Characteristics of Individuals With Germline Mutations in BRCA1 and BRCA2: Analysis of 10,000 Individuals
	Thomas S. Frank, Amie M. Deffenbaugh, Julia E. Reid, Mark Hulick, Brian E. Ward, Beth Lingenfelter, Kathi L. Gumpper, Thomas Scholl, Sean V. Tavtigian, Dmitry R. Pruss, and Gregory C. Critchfield
	JCO Mar 15 2002: 1480–1490. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Women Experience Greater Toxicity With Fluorouracil-Based Chemotherapy for Colorectal Cancer
	Jeff A. Sloan, Richard M. Goldberg, Daniel J. Sargent, Delfino Vargas-Chanes, Suresh Nair, Steven S. Cha, Paul J. Novotny, Michael A. Poon, Michael J. O’Connell, and Charles L. Loprinzi
	JCO Mar 15 2002: 1491–1498. [Abstract] [Full Text] [PDF]
	Combined-Modality Treatment for Resectable Metastatic Colorectal Carcinoma to the Liver: Surgical Resection of Hepatic Metastases in Combination With Continuous Infusion of Chemotherapy—An Intergroup Study
	M. Margaret Kemeny, Sudeshna Adak, Bruce Gray, John S. Macdonald, Thomas Smith, Stuart Lipsitz, Elin R. Sigurdson, Peter J. O’Dwyer, and Al B. Benson, III
	JCO Mar 15 2002: 1499–1505. [Abstract] [Full Text] [PDF]
	Volume of Lymphatic Metastases Does Not Independently Influence Prognosis in Colorectal Cancer
	Jan H. Wong, Susan Steinemann, Paul Tom, Shane Morita, and Pamela Tauchi-Nishi
	JCO Mar 15 2002: 1506–1511. [Abstract] [Full Text] [PDF]
	Gemcitabine Combined With Oxaliplatin in Advanced Pancreatic Adenocarcinoma: Final Results of a GERCOR Multicenter Phase II Study
	C. Louvet, T. André, G. Lledo, P. Hammel, H. Bleiberg, C. Bouleuc, E. Gamelin, M. Flesch, E. Cvitkovic, and A. de Gramont
	JCO Mar 15 2002: 1512–1518. [Abstract] [Full Text] [PDF]
	Randomized, Open-Label, Phase III Study of a 28-Day Oral Regimen of Eniluracil Plus Fluorouracil Versus Intravenous Fluorouracil Plus Leucovorin as First-Line Therapy in Patients With Metastatic/Advanced Colorectal Cancer
	Richard L. Schilsky, Jeremey Levin, William H. West, Alfred Wong, Bruce Colwell, Michael P. Thirlwell, Rafat H. Ansari, William N. Bell, Robin L. White, Barbara B. Yates, Paul V. McGuirt, and Richard Pazdur
	JCO Mar 15 2002: 1519–1526. [Abstract] [Full Text] [PDF]
	Simplified Staging for Hepatocellular Carcinoma
	Jean-Nicolas Vauthey, Gregory Y. Lauwers, Nestor F. Esnaola, Kim-Anh Do, Jacques Belghiti, Nadeem Mirza, Steven A. Curley, Lee M. Ellis, Jean-Marc Regimbeau, Asif Rashid, Karen R. Cleary, and David M. Nagorney
	JCO Mar 15 2002: 1527–1536. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Effect of Graded Testicular Doses of Radiotherapy in Patients Treated for Carcinoma-In-Situ in the Testis
	Peter Meidahl Petersen, Aleksander Giwercman, Gedske Daugaard, Mikael Rørth, Jørgen Holm Petersen, Niels E. Skakkebæk, Steen W. Hansen, and Hans von der Maase
	JCO Mar 15 2002: 1537–1543. [Abstract] [Full Text] [PDF]
	Overexpression of c-met as a Prognostic Indicator for Transitional Cell Carcinoma of the Urinary Bladder: A Comparison With p53 Nuclear Accumulation
	Hong-Lin Cheng, Barry Trink, Tzong-Shin Tzai, Hsiao-Sheng Liu, Shih-Huang Chan, Chung-Liang Ho, David Sidransky, and Nan-Haw Chow
	JCO Mar 15 2002: 1544–1550. [Abstract] [Full Text] [PDF]
	Role of P53 and MDM2 in Treatment Response of Human Germ Cell Tumors
	Anne-Marie F. Kersemaekers, Frank Mayer, Michel Molier, Pascale C. van Weeren, J. Wolter Oosterhuis, Carsten Bokemeyer, and Leendert H.J. Looijenga
	JCO Mar 15 2002: 1551–1561. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Phase I Trial of Intraperitoneal Injection of the E1B-55-kd-Gene–Deleted Adenovirus ONYX-015 (dl1520) Given on Days 1 Through 5 Every 3 Weeks in Patients With Recurrent/Refractory Epithelial Ovarian Cancer
	P. A. Vasey, L. N. Shulman, S. Campos, J. Davis, M. Gore, S. Johnston, D. H. Kirn, V. O’Neill, N. Siddiqui, M. V. Seiden, and S. B. Kaye
	JCO Mar 15 2002: 1562–1569. [Abstract] [Full Text] [PDF]
	Cancer Incidence in a Population of Jewish Women at Risk of Ovarian Cancer
	Alexander Liede, Beth Y. Karlan, Rae Lynn Baldwin, Lawrence D. Platt, Graciela Kuperstein, and Steven A. Narod
	JCO Mar 15 2002: 1570–1577. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Phase III Evaluation of Fluoxetine for Treatment of Hot Flashes
	Charles L. Loprinzi, Jeff A. Sloan, Edith A. Perez, Susan K. Quella, Phillip J. Stella, James A. Mailliard, Michele Y. Halyard, Sandhya Pruthi, Paul J. Novotny, and Teresa A. Rummans
	JCO Mar 15 2002: 1578–1583. [Abstract] [Full Text] [PDF]
	Time Spent in Hospital in the Last Six Months of Life in Patients Who Died of Cancer in Ontario
	J. Huang, C. Boyd, S. Tyldesley, J. Zhang-Salomons, P. A. Groome, and W. J. Mackillop
	JCO Mar 15 2002: 1584–1592. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Phase II Trial of Docetaxel and Cisplatin Combination Chemotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck
	Bonnie S. Glisson, Barbara A. Murphy, Gary Frenette, Fadlo R. Khuri, and Arlene A. Forastiere
	JCO Mar 15 2002: 1593–1599. [Abstract] [Full Text] [PDF]

Melanoma
	Cisplatin, Dacarbazine With or Without Subcutaneous Interleukin-2, and Interferon Alfa-2b in Advanced Melanoma Outpatients: Results From an Italian Multicenter Phase III Randomized Clinical Trial
	Ruggero Ridolfi, Vanna Chiarion-Sileni, Michele Guida, Antonella Romanini, Roberto Labianca, Andrea Freschi, Giovanni Lo Re, Rolando Nortilli, Sonia Brugnara, Patrizia Vitali, and Oriana Nanni
	JCO Mar 15 2002: 1600–1607. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Predictors of Smoking Initiation and Cessation Among Childhood Cancer Survivors: A Report From the Childhood Cancer Survivor Study
	Karen Emmons, Frederick P. Li, John Whitton, Ann C. Mertens, Raymond Hutchinson, Lisa Diller, and Leslie L. Robison
	JCO Mar 15 2002: 1608–1616. [Abstract] [Full Text] [PDF]
	Protracted Intermittent Schedule of Topotecan in Children With Refractory Acute Leukemia: A Pediatric Oncology Group Study
	Wayne L. Furman, Clinton F. Stewart, Mark Kirstein, James L. Kepner, Mark L. Bernstein, Faith Kung, Teresa J. Vietti, C. Philip Steuber, David Lee Becton, Sylvain Baruchel, and Charles Pratt
	JCO Mar 15 2002: 1617–1624. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Prognostic Factors for Malignant Transformation in Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma
	Clara Cesana, Catherine Klersy, Luciana Barbarano, Anna Maria Nosari, Monica Crugnola, Ester Pungolino, Livio Gargantini, Simonetta Granata, Marina Valentini, and Enrica Morra
	JCO Mar 15 2002: 1625–1634. [Abstract] [Full Text] [PDF]

Central Nervous System
	Survival and Failure Patterns of High-Grade Gliomas After Three-Dimensional Conformal Radiotherapy
	June L. Chan, Susan W. Lee, Benedick A. Fraass, Daniel P. Normolle, Harry S. Greenberg, Larry R. Junck, Stephen S. Gebarski, and Howard M. Sandler
	JCO Mar 15 2002: 1635–1642. [Abstract] [Full Text] [PDF]

Sarcomas
	Adjuvant Radiation for Stage II-B Soft Tissue Sarcoma of the Extremity
	Kaled M. Alektiar, Dennis Leung, Michael J. Zelefsky, and Murray F. Brennan
	JCO Mar 15 2002: 1643–1650. [Abstract] [Full Text] [PDF]

Unknown Primary Site Cancer
	Gemcitabine, Carboplatin, and Paclitaxel for Patients With Carcinoma of Unknown Primary Site: A Minnie Pearl Cancer Research Network Study
	F. Anthony Greco, Howard A. Burris, III, Sharlene Litchy, John H. Barton, James E. Bradof, Paul Richards, Daniel C. Scullin, Jr, Joan B. Erland, Lisa H. Morrissey, and John D. Hainsworth
	JCO Mar 15 2002: 1651–1656. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Dose-Finding and Pharmacokinetic Study of Cisplatin, Gemcitabine, and SU5416 in Patients With Solid Tumors
	Bart C. Kuenen, Lee Rosen, Egbert F. Smit, Mandy R.N. Parson, Marcel Levi, Rita Ruijter, Holger Huisman, Marc A. Kedde, Paul Noordhuis, Wim J.F. van der Vijgh, Godefridus J. Peters, Gillian F. Cropp, Paul Scigalla, Klaus Hoekman, Herbert M. Pinedo, and Giuseppe Giaccone
	JCO Mar 15 2002: 1657–1667. [Abstract] [Full Text] [PDF]
	Hepatic Drug Targeting: Phase I Evaluation of Polymer-Bound Doxorubicin
	Leonard W. Seymour, David R. Ferry, David Anderson, Stuart Hesslewood, Peter J. Julyan, Richard Poyner, Jayne Doran, Annie M. Young, Sally Burtles, and David J. Kerr
	JCO Mar 15 2002: 1668–1676. [Abstract] [Full Text] [PDF]
	Doxorubicin Administration by Continuous Infusion Is Not Cardioprotective: The Dana-Farber 91-01 Acute Lymphoblastic Leukemia Protocol
	Steven E. Lipshultz, Amy L. Giantris, Stuart R. Lipsitz, Virginia Kimball Dalton, Barbara L. Asselin, Ronald D. Barr, Luis A. Clavell, Craig A. Hurwitz, Albert Moghrabi, Yvan Samson, Marshall A. Schorin, Richard D. Gelber, Stephen E. Sallan, and Steven D. Colan
	JCO Mar 15 2002: 1677–1682. [Abstract] [Full Text] [PDF]
	Comparative Pharmacokinetic Study of Continuous Venous Infusion Fluorouracil and Oral Fluorouracil With Eniluracil in Patients With Advanced Solid Tumors
	Alex A. Adjei, Joel M. Reid, Robert B Diasio, Jeff A. Sloan, Deborah A. Smith, Joseph Rubin, Henry C. Pitot, Steven R. Alberts, Richard M. Goldberg, Lorelei J. Hanson, Pamela Atherton, Matthew M. Ames, and Charles Erlichman
	JCO Mar 15 2002: 1683–1691. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	Inhibition of KIT Tyrosine Kinase Activity: A Novel Molecular Approach to the Treatment of KIT-Positive Malignancies
	Michael C. Heinrich, Charles D. Blanke, Brian J. Druker, and Christopher L. Corless
	JCO Mar 15 2002: 1692–1703. [Abstract] [Full Text] [PDF]

SPECIAL DEPARTMENTS

CORRESPONDENCE

Quality of Life at the End of Life: How Is the Solution Far Away?

Davide Tassinari, Ilaria Panzini, Alberto Ravaioli, Marco Maltoni, Sergio Sartori, Marit S. Jordhøy, Stein Kaasa, Jon Håvard Loge, and Peter Fayers

JCO Mar 15 2002: 1704–1705. [Full Text] [PDF]

Multimodal Molecular Screening Is Required to Improve the Sensitivity of MLH1 and MSH2 Mutation Analysis

Anne Andermann, Isabelle Thiffault, Nora Wong, Philip Gordon, Elizabeth MacNamara, George Chong, William Foulkes, Antonio Percesepe, Maurizio Ponz de Leon, and Päivi Peltomäki

JCO Mar 15 2002: 1705–1707. [Full Text] [PDF]

Use of Trade Names of Drugs and the Scientific Content of Medical Congresses

Carla Ripamonti, Catherine Sweeney, and Eduardo Bruera

JCO Mar 15 2002: 1707–1708. [Full Text] [PDF]

Following a Trial That Stopped Early: What Next for Adjuvant Hepatic Intra-Arterial Iodine-131 Lipiodol in Resectable Hepatocellular Carcinoma?

S. B. Tan, D. Machin, Y. B. Cheung, Y. F.A. Chung, B. C. Tai, and D. Machin

JCO Mar 15 2002: 1709. [Full Text] [PDF]

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.