EDITORIALS

Thymidylate Synthase Levels: Prognostic, Predictive, or Both?

Carmen Allegra

JCO Apr 1 2002: 1711–1713. [Full Text] [PDF]

Pathologic Evaluation of Total Mesorectal Excision: Big Brother Is Watching

Miguel A. Rodriguez-Bigas

JCO Apr 1 2002: 1714–1715. [Full Text] [PDF]

Referral to Medical Oncologists: Are There Barriers at the Gate?

Alfred I. Neugut and Victor R. Grann

JCO Apr 1 2002: 1716–1718. [Full Text] [PDF]

Breast Cancer Consensus Meetings: Vive la Difference?

Nancy E. Davidson and Mark Levine

JCO Apr 1 2002: 1719–1920. [Full Text] [PDF]

ORIGINAL REPORTS
Gastrointestinal Cancer
	Thymidylate Synthase Expression in Colorectal Cancer: A Prognostic and Predictive Marker of Benefit From Adjuvant Fluorouracil-Based Chemotherapy
	David Edler, Bengt Glimelius, Marja Hallström, Anders Jakobsen, Patrick G. Johnston, Inger Magnusson, Peter Ragnhammar, and Henric Blomgren
	JCO Apr 1 2002: 1721–1728. [Abstract] [Full Text] [PDF]
	Macroscopic Evaluation of Rectal Cancer Resection Specimen: Clinical Significance of the Pathologist in Quality Control
	Iris D. Nagtegaal, Cornelis J.H. van de Velde, Erik van der Worp, Ellen Kapiteijn, Phil Quirke, and J. Han J.M. van Krieken
	JCO Apr 1 2002: 1729–1734. [Abstract] [Full Text] [PDF]
	Investigation of the Prognostic and Predictive Value of Thymidylate Synthase, p53, and Ki-67 in Patients With Locally Advanced Colon Cancer
	Carmen J. Allegra, Allyson L. Parr, Lester E. Wold, Michelle R. Mahoney, Daniel J. Sargent, Patrick Johnston, Pam Klein, Katie Behan, Michael J. O’Connell, Ralph Levitt, John W. Kugler, Maria Tria Tirona, and Richard M. Goldberg
	JCO Apr 1 2002: 1735–1743. [Abstract] [Full Text] [PDF]
	Adjuvant Therapy in Rectal Cancer: Analysis of Stage, Sex, and Local Control—Final Report of Intergroup 0114
	J.E. Tepper, M. O’Connell, D. Niedzwiecki, D.R. Hollis, A.B. Benson, III, B. Cummings, L.L. Gunderson, J.S. Macdonald, J.A. Martenson, and R.J. Mayer
	JCO Apr 1 2002: 1744–1750. [Abstract] [Full Text] [PDF]
	Randomized Trial of Postoperative Adjuvant Therapy in Stage II and III Rectal Cancer to Define the Optimal Sequence of Chemotherapy and Radiotherapy: A Preliminary Report
	Jung-Hee Lee, Je-Hwan Lee, Jin-Hee Ahn, Hyeseung Bahng, Tae-Won Kim, Yoon-Koo Kang, Kyoo-Hyung Lee, Jin-Cheon Kim, Chang-Sik Yu, Jong-Hoon Kim, Seung-Do Ahn, Woo-Kun Kim, Sang-Hee Kim, and Jung-Shin Lee
	JCO Apr 1 2002: 1751–1758. [Abstract] [Full Text] [PDF]
	Phase II Study of Capecitabine and Oxaliplatin in First- and Second-Line Treatment of Advanced or Metastatic Colorectal Cancer
	Markus M. Borner, Daniel Dietrich, Roger Stupp, Rudolf Morant, Hanspeter Honegger, Martin Wernli, Richard Herrmann, Bernhard C. Pestalozzi, Piercarlo Saletti, Silvia Hanselmann, Samuel Müller, Peter Brauchli, Monica Castiglione-Gertsch, Aron Goldhirsch, and Arnaud D. Roth
	JCO Apr 1 2002: 1759–1766. [Abstract] [Full Text] [PDF]
	Acute Oxaliplatin-Induced Peripheral Nerve Hyperexcitability
	Richard H. Wilson, Tanya Lehky, Rebecca R. Thomas, Mary G. Quinn, Mary Kay Floeter, and Jean L. Grem
	JCO Apr 1 2002: 1767–1774. [Abstract] [Full Text] [PDF]
	Tumor Microvessel Density as a Predictor of Recurrence After Resection of Hepatocellular Carcinoma: A Prospective Study
	Ronnie Tung-Ping Poon, Irene Oi-Lin Ng, Cecilia Lau, Wun-Ching Yu, Zhen-Fan Yang, Sheung-Tat Fan, and John Wong
	JCO Apr 1 2002: 1775–1785. [Abstract] [Full Text] [PDF]

Lung Cancer
	Impact of Referral Patterns on the Use of Chemotherapy for Lung Cancer
	Craig C. Earle, Peter J. Neumann, Richard D. Gelber, Milton C. Weinstein, and Jane C. Weeks
	JCO Apr 1 2002: 1786–1792. [Abstract] [Full Text] [PDF]

Breast Cancer
	Prognostic Significance of the Number of Axillary Lymph Nodes Removed in Patients With Node-Negative Breast Cancer
	L. Weir, C. Speers, Y. D’yachkova, and I. A. Olivotto
	JCO Apr 1 2002: 1793–1799. [Abstract] [Full Text] [PDF]
	Phase II Study of Weekly Docetaxel and Trastuzumab for Patients With HER-2–Overexpressing Metastatic Breast Cancer
	Francisco J. Esteva, Vicente Valero, Daniel Booser, Laura T. Guerra, James L. Murray, Lajos Pusztai, Massimo Cristofanilli, Banu Arun, Bita Esmaeli, Herbert A. Fritsche, Nour Sneige, Terry L. Smith, and Gabriel N. Hortobagyi
	JCO Apr 1 2002: 1800–1808. [Abstract] [Full Text] [PDF]
	Adjuvant Therapy for Breast Cancer: Practice Patterns of Community Physicians
	Linda C. Harlan, Jeffrey Abrams, Joan L. Warren, Lin Clegg, Jennifer Stevens, and Rachel Ballard-Barbash
	JCO Apr 1 2002: 1809–1817. [Abstract] [Full Text] [PDF]

Melanoma
	Interferon Alfa Therapy for Malignant Melanoma: A Systematic Review of Randomized Controlled Trials
	Marko B. Lens and Martin Dawes
	JCO Apr 1 2002: 1818–1825. [Abstract] [Full Text] [PDF]
	Tumor Vascularity in the Prognostic Assessment of Primary Cutaneous Melanoma
	Mohammed Kashani-Sabet, Richard W. Sagebiel, Carlos M.M. Ferreira, Mehdi Nosrati, and James R. Miller, III
	JCO Apr 1 2002: 1826–1831. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Randomized Trial of Cisplatin and Ifosfamide With or Without Bleomycin in Squamous Carcinoma of the Cervix: A Gynecologic Oncology Group Study
	Jeffrey D. Bloss, John A. Blessing, Brent C. Behrens, Robert S. Mannel, Janet S. Rader, Anil K. Sood, Maurie Markman, and Jo Benda
	JCO Apr 1 2002: 1832–1837. [Abstract] [Full Text] [PDF]
	Low-Risk Persistent Gestational Trophoblastic Disease: Outcome After Initial Treatment With Low-Dose Methotrexate and Folinic Acid From 1992 to 2000
	I. A. McNeish, S. Strickland, L. Holden, G. J.S. Rustin, M. Foskett, M. J. Seckl, and E. S. Newlands
	JCO Apr 1 2002: 1838–1844. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Excellent Disease Control and Survival in Patients With Advanced Nasopharyngeal Cancer Treated With Chemoradiation
	Danny Rischin, June Corry, Jennifer Smith, Josephine Stewart, Peter Hughes, and Lester Peters
	JCO Apr 1 2002: 1845–1852. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Risk of Positive Margins and Biochemical Recurrence in Relation to Nerve-Sparing Radical Prostatectomy
	Mario Sofer, Kara L. Hamilton-Nelson, James J. Schlesselman, and Mark S. Soloway
	JCO Apr 1 2002: 1853–1858. [Abstract] [Full Text] [PDF]
	Phase II Study of Paclitaxel Plus Gemcitabine in Refractory Germ Cell Tumors (E9897): A Trial of the Eastern Cooperative Oncology Group
	Stuart Hinton, Paul Catalano, Lawrence H. Einhorn, Patrick J. Loehrer, Sr, Timothy Kuzel, David Vaughn, and George Wilding
	JCO Apr 1 2002: 1859–1863. [Abstract] [Full Text] [PDF]
	Extragonadal Germ Cell Tumors of the Mediastinum and Retroperitoneum: Results From an International Analysis
	Carsten Bokemeyer, Craig R. Nichols, Jean-P. Droz, Hans-J. Schmoll, Alan Horwich, Arthur Gerl, Sophie D. Fossa, Jörg Beyer, Jörg Pont, Lothar Kanz, Lawrence Einhorn, and Jörg T. Hartmann
	JCO Apr 1 2002: 1864–1873. [Abstract] [Full Text] [PDF]
	Characterization of a Novel Prostate-Specific Antigen–Activated Peptide-Doxorubicin Conjugate in Patients With Prostate Cancer
	Robert S. DiPaola, John Rinehart, John Nemunaitis, Scott Ebbinghaus, Eric Rubin, Terry Capanna, Marie Ciardella, Susan Doyle-Lindrud, Susan Goodwin, Michelle Fontaine, Ned Adams, Adrienne Williams, Michael Schwartz, Greg Winchell, Karen Wickersham, Paul Deutsch, and Siu-Long Yao
	JCO Apr 1 2002: 1874–1879. [Abstract] [Full Text] [PDF]
	Knowledge and Experience Regarding Cancer, Infertility, and Sperm Banking in Younger Male Survivors
	Leslie R. Schover, Kimberly Brey, Alan Lichtin, Larry I. Lipshultz, and Sima Jeha
	JCO Apr 1 2002: 1880–1889. [Abstract] [Full Text] [PDF]
	Oncologists’ Attitudes and Practices Regarding Banking Sperm Before Cancer Treatment
	Leslie R. Schover, Kimberly Brey, Alan Lichtin, Larry I. Lipshultz, and Sima Jeha
	JCO Apr 1 2002: 1890–1897. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	AspergillusGalactomannan Detection in the Diagnosis of Invasive Aspergillosis in Cancer Patients
	Raoul Herbrecht, Valérie Letscher-Bru, Corina Oprea, Bruno Lioure, Jocelyn Waller, France Campos, Odile Villard, Kun-Lun Liu, Shanti Natarajan-Amé, Patrick Lutz, Patrick Dufour, Jean-Pierre Bergerat, and Ermanno Candolfi
	JCO Apr 1 2002: 1898–1906. [Abstract] [Full Text] [PDF]
	Psychiatric Morbidity and Impact on Hospital Length of Stay Among Hematologic Cancer Patients Receiving Stem-Cell Transplantation
	Jesús M. Prieto, Jordi Blanch, Jorge Atala, Enric Carreras, Montserrat Rovira, Esteve Cirera, and Cristóbal Gastó
	JCO Apr 1 2002: 1907–1917. [Abstract] [Full Text] [PDF]
	Safe and Cost Effective Use of Alteplase for the Clearance of Occluded Central Venous Access Devices
	J. P. Timoney, M. G. Malkin, D. M. Leone, J. S. Groeger, M. L. Heaney, D. L. Keefe, M. Klang, C. D. Lucarelli, R. J. Muller, S. L. Eng, M. Connor, T. N. Small, A. E. Brown, and L. B. Saltz
	JCO Apr 1 2002: 1918–1922. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors
	Maja J.A. de Jonge, Cornelis J.A. Punt, Alex Sparreboom, André S.T. Planting, M.E.W.J. Peters, Jacqueline van de Schraaf, Ann Jackman, Rob Smith, Pieter H.M. de Mulder, and Jaap Verweij
	JCO Apr 1 2002: 1923–1931. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	DNA Microarrays in Clinical Oncology
	Sridhar Ramaswamy and Todd R. Golub
	JCO Apr 1 2002: 1932–1941. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Unusual Presentations of Lymphoma: Case 1. Sea-Blue Histiocytes in Non-Hodgkin's Lymphoma

Thein H. Oo, Leo S. Aish, and Hani Hassoun

JCO Apr 1 2002: 1942–1943. [Full Text] [PDF]

Unusual Presentations of Lymphoma: Case 2. Non-Hodgkin's Lymphoma Presenting as Liver Disease

Raymond S. McDermott, Michael M. Maher, Kieron Dunleavy, Conor J. O’Keane, John P. Stack, and Desmond P. Carney

JCO Apr 1 2002: 1943–1946. [Full Text] [PDF]

Unusual Presentations of Lymphoma: Case 3. Splenic Hematoma Associated With Non-Hodgkin's Lymphoma

Parthas Narasimhan, Ibrahim F. Hitti, Parul Gheewala, Usha Pulakhandam, and Barry Kanzer

JCO Apr 1 2002: 1946–1947. [Full Text] [PDF]

ART OF ONCOLOGY

Looking at the Dying Patient: The Ferdinand Hodler Paintings of Valentine Godé-Darel

Bernhard C. Pestalozzi

JCO Apr 1 2002: 1948–1950. [Full Text] [PDF]

SPECIAL DEPARTMENTS

CORRESPONDENCE

Enhanced Oral Bioavailability of Docetaxel by Coadministration of Cyclosporine: Quantitation and Role of P-Glycoprotein

Win L. Chiou, Ta Chen Wu, Chien Ma, Hyun Young Jeong, M.M. Malingré, J.H. Beijnen, and J.H.M. Schellens

JCO Apr 1 2002: 1951–1952. [Full Text] [PDF]

The Art of Oncology: When the Tumor Is Not the Target—The Power of Silence

Ruprecht Nitschke and Bruce Himelstein

JCO Apr 1 2002: 1952–1953. [Full Text] [PDF]

High-Dose Samarium-153 Ethylene Diamine Tetramethylene Phosphonate: Low Toxicity of Skeletal Irradiation in Patients With Osteosarcoma and Bone Metastases

Christine Franzius, Andreas Schuck, and Stefan S. Bielack

JCO Apr 1 2002: 1953–1954. [Full Text] [PDF]

Equivalence Between Ovarian Suppression and Chemotherapy in the Adjuvant Treatment of Endocrine-Responsive Breast Cancer

Angelo Di Leo and Marc Buyse

JCO Apr 1 2002: 1954–1955. [Full Text] [PDF]

Meeting Highlights: International Consensus Panel on the Treatment of Primary Breast Cancer

Richard R. Love, Aron Goldhirsch, John H. Glick, Richard D. Gelber, Alan S. Coates, and Hans-Jörg Senn

JCO Apr 1 2002: 1955–1957. [Full Text] [PDF]

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