EDITORIALS

Pemetrexed and Cisplatin for Malignant Pleural Mesothelioma: A New Standard of Care?

Valerie W. Rusch

JCO Jul 15 2003: 2629–2630. [Full Text] [PDF]

Combining Cytotoxic Chemotherapy With Cyclooxygenase-2 Inhibition

Ethan Dmitrovsky

JCO Jul 15 2003: 2631–2632. [Full Text] [PDF]

Estimation of the Glomerular Filtration Rate in Cancer Patients: A New Formula for New Drugs

Patrick T. Murray and Mark J. Ratain

JCO Jul 15 2003: 2633–2635. [Full Text] [PDF]

ORIGINAL REPORTS
Lung Cancer
	Phase III Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin Alone in Patients With Malignant Pleural Mesothelioma
	Nicholas J. Vogelzang, James J. Rusthoven, James Symanowski, Claude Denham, E. Kaukel, Pierre Ruffie, Ulrich Gatzemeier, Michael Boyer, Salih Emri, Christian Manegold, Clet Niyikiza, and Paolo Paoletti
	JCO Jul 15 2003: 2636–2644. [Abstract] [Full Text] [PDF]
	Celecoxib, a Selective Cyclo-Oxygenase-2 Inhibitor, Enhances the Response to Preoperative Paclitaxel and Carboplatin in Early-Stage Non–Small-Cell Lung Cancer
	N.K. Altorki, R.S. Keresztes, J.L. Port, D.M. Libby, R.J. Korst, D.B. Flieder, C.A. Ferrara, D.F. Yankelevitz, K. Subbaramaiah, M.W. Pasmantier, and A.J. Dannenberg
	JCO Jul 15 2003: 2645–2650. [Abstract] [Full Text] [PDF]
	Positron Emission Tomography in Non–Small-Cell Lung Cancer: Prediction of Response to Chemotherapy by Quantitative Assessment of Glucose Use
	Wolfgang A. Weber, Volker Petersen, Burkhard Schmidt, Leishia Tyndale-Hines, Thomas Link, Christian Peschel, and Markus Schwaiger
	JCO Jul 15 2003: 2651–2657. [Abstract] [Full Text] [PDF]
	Gefitinib in Pretreated Non–Small-Cell Lung Cancer (NSCLC): Analysis of Efficacy and Correlation With HER2 and Epidermal Growth Factor Receptor Expression in Locally Advanced or Metastatic NSCLC
	Federico Cappuzzo, Vanesa Gregorc, Elisa Rossi, Alessandra Cancellieri, Elisabetta Magrini, Carlo Terenzio Paties, Giovanni Ceresoli, Laura Lombardo, Stefania Bartolini, Cesare Calandri, Marisa De Rosa, Eugenio Villa, and Lucio Crinò
	JCO Jul 15 2003: 2658–2663. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Dose-Escalating and Pharmacological Study of Oxaliplatin in Adult Cancer Patients With Impaired Renal Function: A National Cancer Institute Organ Dysfunction Working Group Study
	Chris H. Takimoto, Scot C. Remick, Sunil Sharma, Sridhar Mani, Ramesh K. Ramanathan, James Doroshow, Anne Hamilton, Daniel Mulkerin, Martin Graham, Graham F. Lockwood, Percy Ivy, Merrill Egorin, Barbara Schuler, Denis Greenslade, Andrew Goetz, Ronald Knight, Rebecca Thomas, Brian P. Monahan, William Dahut, and Jean L. Grem
	JCO Jul 15 2003: 2664–2672. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Androgen Receptor Mutations in Androgen-Independent Prostate Cancer: Cancer and Leukemia Group B Study 9663
	Mary-Ellen Taplin, Barur Rajeshkumar, Susan Halabi, Cary P. Werner, Bruce A. Woda, Joel Picus, Walter Stadler, Daniel F. Hayes, Philip W. Kantoff, Nicholas J. Vogelzang, and Eric J. Small
	JCO Jul 15 2003: 2673–2678. [Abstract] [Full Text] [PDF]
	Cluster Analysis of p53 and Ki67 Expression, Apoptosis, Alpha-Fetoprotein, and Human Chorionic Gonadotrophin Indicates a Favorable Prognostic Subgroup Within the Embryonal Carcinoma Germ Cell Tumor
	Madhu Mazumdar, Jennifer Bacik, Satish K. Tickoo, Deborah Dobrzynski, Alessia Donadio, Dean Bajorin, Robert Motzer, Victor Reuter, and George J. Bosl
	JCO Jul 15 2003: 2679–2688. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Prospective, Randomized, Multicenter Trial on the Antiproliferative Effect of Lanreotide, Interferon Alfa, and Their Combination for Therapy of Metastatic Neuroendocrine Gastroenteropancreatic Tumors—The International Lanreotide and Interferon Alfa Study Group
	Siegbert Faiss, Ulrich-Frank Pape, Michael Böhmig, Yvonne Dörffel, Ulrich Mansmann, Werner Golder, Ernst Otto Riecken, and Bertram Wiedenmann
	JCO Jul 15 2003: 2689–2696. [Abstract] [Full Text] [PDF]
	Long-Term Toxicity After Definitive Chemoradiotherapy for Squamous Cell Carcinoma of the Thoracic Esophagus
	Satoshi Ishikura, Keiji Nihei, Atsushi Ohtsu, Narikazu Boku, Shuichi Hironaka, Kiyomi Mera, Manabu Muto, Takashi Ogino, and Shigeaki Yoshida
	JCO Jul 15 2003: 2697–2702. [Abstract] [Full Text] [PDF]
	Oxaliplatin With Weekly Bolus Fluorouracil and Low-Dose Leucovorin as First-Line Therapy for Patients With Colorectal Cancer
	Howard Hochster, Abraham Chachoua, James Speyer, Juliette Escalon, Anne Zeleniuch-Jacquotte, and Franco Muggia
	JCO Jul 15 2003: 2703–2707. [Abstract] [Full Text] [PDF]

Breast Cancer
	HER-2 Expression and Cell Proliferation: Prognostic Markers in Patients With Node-Negative Breast Cancer
	Annalisa Volpi, Oriana Nanni, Franca De Paola, Anna Maria Granato, Annita Mangia, Franco Monti, Francesco Schittulli, Mario De Lena, Emanuela Scarpi, Paola Rosetti, Manlio Monti, Lorenzo Gianni, Dino Amadori, and Angelo Paradiso
	JCO Jul 15 2003: 2708–2712. [Abstract] [Full Text] [PDF]
	The Role of Irradiation of the Internal Mammary Lymph Nodes in High-Risk Stage II to IIIA Breast Cancer Patients After High-Dose Chemotherapy: A Prospective Sequential Nonrandomized Study
	Salomon M. Stemmer, Shulamith Rizel, Izhar Hardan, Adamous Adamo, Avivit Neumann, Jana Goffman, Harold J. Brenner, and M. Raphael Pfeffer
	JCO Jul 15 2003: 2713–2718. [Abstract] [Full Text] [PDF]

Sarcomas
	Localized Extremity Soft Tissue Sarcoma: Improved Knowledge With Unchanged Survival Over Time
	Jürgen Weitz, Christina R. Antonescu, and Murray F. Brennan
	JCO Jul 15 2003: 2719–2725. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Chemotherapy Alone as Initial Treatment for Primary CNS Lymphoma in Patients Older Than 60 Years: A Multicenter Phase II Study (26952) of the European Organization for Research and Treatment of Cancer Brain Tumor Group
	K. Hoang-Xuan, L. Taillandier, O. Chinot, P. Soubeyran, U. Bogdhan, J. Hildebrand, M. Frenay, N. De Beule, J.Y. Delattre, and B. Baron
	JCO Jul 15 2003: 2726–2731. [Abstract] [Full Text] [PDF]
	DTPACE: An Effective, Novel Combination Chemotherapy With Thalidomide for Previously Treated Patients With Myeloma
	Choon-Kee Lee, Bart Barlogie, Nikhil Munshi, Maurizio Zangari, Athanasios Fassas, Joth Jacobson, Frits van Rhee, Michele Cottler-Fox, Firas Muwalla, and Guido Tricot
	JCO Jul 15 2003: 2732–2739. [Abstract] [Full Text] [PDF]
	Intestinal Non-Hodgkin’s Lymphoma: A Multicenter Prospective Clinical Study From the German Study Group on Intestinal Non-Hodgkin’s Lymphoma
	Severin Daum, Reiner Ullrich, Walter Heise, Bettina Dederke, Hans-Dieter Foss, Harald Stein, Eckhard Thiel, Martin Zeitz, and Ernst-Otto Riecken
	JCO Jul 15 2003: 2740–2746. [Abstract] [Full Text] [PDF]
	Evidence of a Graft-Versus-Leukemia Effect in Chronic Lymphocytic Leukemia After Reduced-Intensity Conditioning and Allogeneic Stem-Cell Transplantation: The Cooperative German Transplant Study Group
	J. Schetelig, C. Thiede, M. Bornhäuser, R. Schwerdtfeger, M. Kiehl, J. Beyer, H.G. Sayer, N. Kröger, M. Hensel, C. Scheffold, T.K. Held, K. Höffken, A.D. Ho, J. Kienast, A. Neubauer, A.R. Zander, A.A. Fauser, G. Ehninger, and W. Siegert
	JCO Jul 15 2003: 2747–2753. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Assessment of Quality of Life in Outpatients With Advanced Cancer: The Accuracy of Clinician Estimations and the Relevance of Spiritual Well-Being—A Hoosier Oncology Group Study
	Michael J. Fisch, Michael L. Titzer, Jean L. Kristeller, Jianzhao Shen, Patrick J. Loehrer, Sin-Ho Jung, Steven D. Passik, and Lawrence H. Einhorn
	JCO Jul 15 2003: 2754–2759. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	Combined-Modality Treatment of Solid Tumors Using Radiotherapy and Molecular Targeted Agents
	Brigette B.Y. Ma, Robert G. Bristow, John Kim, and Lillian L. Siu
	JCO Jul 15 2003: 2760–2776. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLES
	American Society of Clinical Oncology Policy Statement Update: Tobacco Control—Reducing Cancer Incidence and Saving Lives
	JCO Jul 15 2003: 2777–2786. First published on May 31 2003; 10.1200/JCO.2003.04.154. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Status of Epidermal Growth Factor Receptor Antagonists in the Biology and Treatment of Cancer
	John Mendelsohn and Jose Baselga
	JCO Jul 15 2003: 2787–2799. [Abstract] [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Randomized Clinical Trial of an Implantable Drug Delivery System

Mellar P. Davis, Declan Walsh, Ruth Lagman, and Susan B. LeGrand

JCO Jul 15 2003: 2800–2801. [Full Text] [PDF]

Randomized Clinical Trial of an Implantable Drug Delivery System Compared With Comprehensive Medical Management for Refractory Cancer Pain: Impact on Pain, Drug-Related Toxicity, and Survival

Carla Ripamonti and Cinzia Brunelli

JCO Jul 15 2003: 2801–2802. [Full Text] [PDF]

In reply:

Thomas J. Smith, Peter Staats, and Patrick J. Coyne

JCO Jul 15 2003: 2802–2803. [Full Text] [PDF]

Paclitaxel Pharmacokinetics, Threshold Models, and Dosing Strategies

Alex Sparreboom and Jaap Verweij

JCO Jul 15 2003: 2803–2804. [Full Text] [PDF]

To the Editor:

Martine Extermann

JCO Jul 15 2003: 2804–2805. [Full Text] [PDF]

In reply:

Merrill J. Egorin

JCO Jul 15 2003: 2805–2806. [Full Text] [PDF]

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