EDITORIALS

Toward Optimal Central Nervous System–Directed Treatment in Childhood Acute Lymphoblastic Leukemia

Ching-Hon Pui

JCO Jan 15 2003: 179–181. [Full Text] [PDF]

Horseshoes, Hand Grenades, and Body-Surface Area–Based Dosing: Aiming for a Target

Merrill J. Egorin

JCO Jan 15 2003: 182–183. [Full Text] [PDF]

ORIGINAL REPORTS
Pediatric Oncology
	Diagnostic Cerebrospinal Fluid Examination in Children With Acute Lymphoblastic Leukemia: Significance of Low Leukocyte Counts With Blasts or Traumatic Lumbar Puncture
	Britta Bürger, Martin Zimmermann, Georg Mann, Joachim Kühl, Lutz Löning, Hansjörg Riehm, Alfred Reiter, and Martin Schrappe
	JCO Jan 15 2003: 184–188. [Abstract] [Full Text] [PDF]
	Smoking Among Participants in the Childhood Cancer Survivors Cohort: The Partnership for Health Study
	Karen M. Emmons, Rita M. Butterfield, Elaine Puleo, Elyse R. Park, Ann Mertens, Ellen R. Gritz, Maureen Lahti, and Fredrick P. Li
	JCO Jan 15 2003: 189–196. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Randomized Cross-Over Evaluation of Body-Surface Area–Based Dosing Versus Flat-Fixed Dosing of Paclitaxel
	Carolien H. Smorenburg, Alex Sparreboom, Marijke Bontenbal, Gerrit Stoter, Kees Nooter, and Jaap Verweij
	JCO Jan 15 2003: 197–202. [Abstract] [Full Text] [PDF]
	Use of Positron Emission Tomography in Pharmacokinetic Studies to Investigate Therapeutic Advantage in a Phase I Study of 120-Hour Intravenous Infusion XR5000
	D.J. Propper, J. de Bono, A. Saleem, S. Ellard, E. Flanagan, J. Paul, T.S. Ganesan, D.C. Talbot, E.O. Aboagye, P. Price, A.L. Harris, and C. Twelves
	JCO Jan 15 2003: 203–210. [Abstract] [Full Text] [PDF]
	Cantuzumab Mertansine, a Maytansinoid Immunoconjugate Directed to the CanAg Antigen: A Phase I, Pharmacokinetic, and Biologic Correlative Study
	Anthony W. Tolcher, Leonel Ochoa, Lisa A. Hammond, Amita Patnaik, Tam Edwards, Chris Takimoto, Lon Smith, Johann de Bono, Garry Schwartz, Theresa Mays, Zdenka L. Jonak, Randall Johnson, Mark DeWitte, Helen Martino, Charlene Audette, Kate Maes, Ravi V.J. Chari, John M. Lambert, and Eric K. Rowinsky
	JCO Jan 15 2003: 211–222. [Abstract] [Full Text] [PDF]
	Phase I Pharmacokinetic and Pharmacodynamic Study of Recombinant Human Endostatin in Patients With Advanced Solid Tumors
	James P. Thomas, Rhoda Z. Arzoomanian, Dona Alberti, Rebecca Marnocha, Fred Lee, Andreas Friedl, Kendra Tutsch, Amy Dresen, Peter Geiger, James Pluda, William Fogler, Joan H. Schiller, and George Wilding
	JCO Jan 15 2003: 223–231. [Abstract] [Full Text] [PDF]
	SarCNU, a Nitrosourea Analog on a Day 1, 5, and 9 Oral Schedule: A Phase I and Pharmacokinetic Study in Patients With Advanced Solid Tumors
	L. Panasci, S.F. Stinson, D. Melnychuk, V. Sandor, W.H. Miller, Jr, G. Batist, F. Patenaude, N. Bangash, L. Panarello, M. Alaoui-Jamali, and E. Sausville
	JCO Jan 15 2003: 232–240. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Prognostic Value of Thymidylate Synthase, Ki-67, and p53 in Patients With Dukes’ B and C Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study
	Carmen J. Allegra, Soon Paik, Linda H. Colangelo, Allyson L. Parr, Ilan Kirsch, George Kim, Pamela Klein, Patrick G. Johnston, Norman Wolmark, and H. Samuel Wieand
	JCO Jan 15 2003: 241–250. [Abstract] [Full Text] [PDF]

Central Nervous System
	Phase II Trial of Procarbazine, Lomustine, and Vincristine as Initial Therapy for Patients With Low-Grade Oligodendroglioma or Oligoastrocytoma: Efficacy and Associations With Chromosomal Abnormalities
	Jan C. Buckner, Dean Gesme, Jr, Judith R. O’Fallon, Julie E. Hammack, Scott Stafford, Paul D. Brown, Roland Hawkins, Bernd W. Scheithauer, Bradley J. Erickson, Ralph Levitt, Edward G. Shaw, and Robert Jenkins
	JCO Jan 15 2003: 251–255. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Morphologic Dysplasia in De Novo Acute Myeloid Leukemia (AML) Is Related to Unfavorable Cytogenetics but Has No Independent Prognostic Relevance Under the Conditions of Intensive Induction Therapy: Results of a Multiparameter Analysis From the German AML Cooperative Group Studies
	Torsten Haferlach, Claudia Schoch, Helmut Löffler, Winfried Gassmann, Wolfgang Kern, Susanne Schnittger, Christa Fonatsch, Wolf-Dieter Ludwig, Christian Wuchter, Brigitte Schlegelberger, Peter Staib, Albrecht Reichle, Uschi Kubica, Hartmut Eimermacher, Leopold Balleisen, Andreas Grüneisen, Detlef Haase, Carlo Aul, Jochen Karow, Eva Lengfelder, Bernhard Wörmann, Achim Heinecke, Maria Cristina Sauerland, Thomas Büchner, and Wolfgang Hiddemann
	JCO Jan 15 2003: 256–265. [Abstract] [Full Text] [PDF]
	Prognostic Scoring System for Primary CNS Lymphomas: The International Extranodal Lymphoma Study Group Experience
	Andrés J.M. Ferreri, Jean-Yves Blay, Michele Reni, Felice Pasini, Michele Spina, Achille Ambrosetti, Antonello Calderoni, Andrea Rossi, Vittorio Vavassori, Annarita Conconi, Liliana Devizzi, Françoise Berger, Maurilio Ponzoni, Bettina Borisch, Marianne Tinguely, Michele Cerati, Mario Milani, Enrico Orvieto, Juvenal Sanchez, Christine Chevreau, Stefania Dell’Oro, Emanuele Zucca, and Franco Cavalli
	JCO Jan 15 2003: 266–272. [Abstract] [Full Text] [PDF]
	Additional Prognostic Value of Bone Marrow Histology in Patients Subclassified According to the International Prognostic Scoring System for Myelodysplastic Syndromes
	E. Verburgh, R. Achten, B. Maes, A. Hagemeijer, M. Boogaerts, C. De Wolf-Peeters, and G. Verhoef
	JCO Jan 15 2003: 273–282. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Evaluation of Monoclonal Humanized Anti-HER2 Antibody, Trastuzumab, in Patients With Recurrent or Refractory Ovarian or Primary Peritoneal Carcinoma With Overexpression of HER2: A Phase II Trial of the Gynecologic Oncology Group
	Michael A. Bookman, Kathleen M. Darcy, Daniel Clarke-Pearson, Richard A. Boothby, and Ira R. Horowitz
	JCO Jan 15 2003: 283–290. [Abstract] [Full Text] [PDF]
	Phase II Trial of Irinotecan in Patients With Metastatic Epithelial Ovarian Cancer or Peritoneal Cancer
	Diane C. Bodurka, Charles Levenback, Judith K. Wolf, Jacalyn Gano, J. Taylor Wharton, John J. Kavanagh, and David M. Gershenson
	JCO Jan 15 2003: 291–297. [Abstract] [Full Text] [PDF]

Breast Cancer
	Randomized Trial Comparing Six Versus Three Cycles of Epirubicin-Based Adjuvant Chemotherapy in Premenopausal, Node-Positive Breast Cancer Patients: 10-Year Follow-Up Results of the French Adjuvant Study Group 01 Trial
	Pierre Fumoleau, Pierre Kerbrat, Pascale Romestaing, Pierre Fargeot, Alain Brémond, Moïse Namer, Simon Schraub, Marie-Jo Goudier, Jeanne Mihura, Alain Monnier, Pierre Clavère, Daniel Serin, Philippe Seffert, Christiane Pourny, Thomas Facchini, Jean-Philippe Jacquin, Jean-François Sztermer, Jean Datchary, René Ramos, and Elisabeth Luporsi
	JCO Jan 15 2003: 298–305. [Abstract] [Full Text] [PDF]

Melanoma
	Survivin, bcl-2, bax, and bcl-X Gene Expression in Sentinel Lymph Nodes From Melanoma Patients
	Angela Gradilone, Paola Gazzaniga, Diego Ribuffo, Susanna Scarpa, Emanuele Cigna, Fortunata Vasaturo, Ugo Bottoni, Daniele Innocenzi, Stefano Calvieri, Nicolo’ Scuderi, Luigi Frati, and Anna Maria Aglianò
	JCO Jan 15 2003: 306–312. [Abstract] [Full Text] [PDF]
	Humoral Immune Response to a Therapeutic Polyvalent Cancer Vaccine After Complete Resection of Thick Primary Melanoma and Sentinel Lymphadenectomy
	Mathew H. Chung, Rishab K. Gupta, Eddy Hsueh, Richard Essner, Wei Ye, Reynold Yee, and Donald L. Morton
	JCO Jan 15 2003: 313–319. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Weekly Carboplatin and Paclitaxel Followed by Concomitant Paclitaxel, Fluorouracil, and Hydroxyurea Chemoradiotherapy: Curative and Organ-Preserving Therapy for Advanced Head and Neck Cancer
	Everett E. Vokes, Kerstin Stenson, Fred R. Rosen, Merrill S. Kies, Alfred W. Rademaker, Mary Ellyn Witt, Bruce E. Brockstein, Marcy A. List, Bing Bing Fung, Louis Portugal, Bharat B. Mittal, Harold Pelzer, Ralph R. Weichselbaum, and Daniel J. Haraf
	JCO Jan 15 2003: 320–326. [Abstract] [Full Text] [PDF]
	Primary Chemotherapy in Resectable Oral Cavity Squamous Cell Cancer: A Randomized Controlled Trial
	Lisa Licitra, Cesare Grandi, Marco Guzzo, Luigi Mariani, Salvatore Lo Vullo, Francesca Valvo, Pasquale Quattrone, Pinuccia Valagussa, Gianni Bonadonna, Roberto Molinari, and Giulio Cantù
	JCO Jan 15 2003: 327–333. [Abstract] [Full Text] [PDF]

Sarcomas
	Osteosarcoma of the Pelvis: Experience of the Cooperative Osteosarcoma Study Group
	Toshifumi Ozaki, Silke Flege, Matthias Kevric, Norbert Lindner, Rainer Maas, Günter Delling, Rudolf Schwarz, Arthur R. von Hochstetter, Mechthild Salzer-Kuntschik, Wolfgang E. Berdel, Heribert Jürgens, G. Ulrich Exner, Peter Reichardt, Regine Mayer-Steinacker, Volker Ewerbeck, Rainer Kotz, Winfried Winkelmann, and Stefan S. Bielack
	JCO Jan 15 2003: 334–341. [Abstract] [Full Text] [PDF]
	Metachronous Skeletal Osteosarcoma in Patients Treated with Adjuvant and Neoadjuvant Chemotherapy for Nonmetastatic Osteosarcoma
	LeLe Aung, Richard Gorlick, John H. Healey, Weiji Shi, Howard T. Thaler, Nicholas A. Shorter, Andrew G. Huvos, and Paul A. Meyers
	JCO Jan 15 2003: 342–348. [Abstract] [Full Text] [PDF]

Lung Cancer
	Combination of Raltitrexed and Oxaliplatin Is an Active Regimen in Malignant Mesothelioma: Results of a Phase II Study
	K. Fizazi, H. Doubre, T. Le Chevalier, A. Riviere, J. Viala, C. Daniel, L. Robert, P. Barthélemy, A. Fandi, and P. Ruffié
	JCO Jan 15 2003: 349–354. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Brief Physician-Initiated Quit-Smoking Strategies for Clinical Oncology Settings: A Trial Coordinated by the Eastern Cooperative Oncology Group
	Robert A. Schnoll, Bin Zhang, Montserrat Rue, James E. Krook, Wayne T. Spears, Alfred C. Marcus, and Paul F. Engstrom
	JCO Jan 15 2003: 355–365. [Abstract] [Full Text] [PDF]
	Epoetin Alfa Treatment Results in Clinically Significant Improvements in Quality of Life in Anemic Cancer Patients When Referenced to the General Population
	David Cella, Martin J. Zagari, Christina Vandoros, Dennis D. Gagnon, Hans-Jürgen Hurtz, and Johan W.R. Nortier
	JCO Jan 15 2003: 366–373. [Abstract] [Full Text] [PDF]
	Feasibility and Compliance of Automated Measurement of Quality of Life in Oncology Practice
	E.P. Wright, P.J. Selby, M. Crawford, A. Gillibrand, C. Johnston, T.J. Perren, R. Rush, A. Smith, G. Velikova, K. Watson, A. Gould, and A. Cull
	JCO Jan 15 2003: 374–382. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Biology of Prostate-Specific Antigen
	Steven P. Balk, Yoo-Joung Ko, and Glenn J. Bubley
	JCO Jan 15 2003: 383–391. [Abstract] [Full Text] [PDF]

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