EDITORIALS

Early Detection of Lung Cancer Using Serum RNA or DNA Markers: Ready for Prime Time or for Validation?

Paul A. Bunn, Jr

JCO Nov 1 2003: 3891–3893. First published on Sep 24 2003; 10.1200/JCO.2003.07.976. [Full Text] [PDF]

High-Dose Therapy for Follicular Lymphoma Revisited: Not If, but When?

T. Andrew Lister

JCO Nov 1 2003: 3894–3896. First published on Sep 29 2003; 10.1200/JCO.2003.07.981. [Full Text] [PDF]

Antiangiogenic Therapy: More Promise and, Yet Again, More Questions

Lee M. Ellis

JCO Nov 1 2003: 3897–3899. First published on Sep 29 2003; 10.1200/JCO.2003.07.977. [Full Text] [PDF]

Is Trastuzumab Every Three Weeks Ready for Prime Time?

Melody Cobleigh and David Frame

JCO Nov 1 2003: 3900–3901. First published on Sep 24 2003; 10.1200/JCO.2003.07.984. [Full Text] [PDF]

ORIGINAL REPORTS
Lung Cancer
	Quantification of Free Circulating DNA As a Diagnostic Marker in Lung Cancer
	Gabriella Sozzi, Davide Conte, MariaElena Leon, Rosalia Cirincione, Luca Roz, Cathy Ratcliffe, Elena Roz, Nicola Cirenei, Massimo Bellomi, Giuseppe Pelosi, Marco A. Pierotti, and Ugo Pastorino
	JCO Nov 1 2003: 3902–3908. First published on Sep 24 2003; 10.1200/JCO.2003.02.006. [Abstract] [Full Text] [PDF]
	Three-Arm Randomized Study of Two Cisplatin-Based Regimens and Paclitaxel Plus Gemcitabine in Advanced Non–Small-Cell Lung Cancer: A Phase III Trial of the European Organization for Research and Treatment of Cancer Lung Cancer Group—EORTC 08975
	Egbert F. Smit, Jan P.A.M. van Meerbeeck, Pilar Lianes, Channa Debruyne, Catherine Legrand, Franz Schramel, Hans Smit, Rabab Gaafar, Bonne Biesma, Chris Manegold, Niels Neymark, and Giuseppe Giaccone
	JCO Nov 1 2003: 3909–3917. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	High-Dose Therapy Improves Progression-Free Survival and Survival in Relapsed Follicular Non-Hodgkin’s Lymphoma: Results From the Randomized European CUP Trial
	Harry C. Schouten, Wendi Qian, Stein Kvaloy, Adolfo Porcellini, Hans Hagberg, Hans Erik Johnsen, Jeanette K. Doorduijn, Matthew R. Sydes, and Gunnar Kvalheim
	JCO Nov 1 2003: 3918–3927. First published on Sep 29 2003; 10.1200/JCO.2003.10.023. [Abstract] [Full Text] [PDF]
	Binet’s Staging System and VH Genes Are Independent but Complementary Prognostic Indicators in Chronic Lymphocytic Leukemia
	Yuri Vasconcelos, Frédéric Davi, Vincent Levy, Pablo Oppezzo, Christian Magnac, Ariane Michel, Mihoko Yamamoto, Otto Pritsch, Hélène Merle-Béral, Karim Maloum, Florence Ajchenbaum-Cymbalista, and Guillaume Dighiero
	JCO Nov 1 2003: 3928–3932. [Abstract] [Full Text] [PDF]
	Assessment of Differences in Patient Populations Selected for or Excluded From Participation in Clinical Phase III Acute Myelogenous Leukemia Trials
	Catherine Mengis, Stefan Aebi, Andreas Tobler, Werner Dähler, and Martin F. Fey
	JCO Nov 1 2003: 3933–3939. [Abstract] [Full Text] [PDF]
	Two Immunoglobulin G Fragment C Receptor Polymorphisms Independently Predict Response to Rituximab in Patients With Follicular Lymphoma
	Wen-Kai Weng and Ronald Levy
	JCO Nov 1 2003: 3940–3947. First published on Sep 15 2003; 10.1200/JCO.2003.05.013. [Abstract] [Full Text] [PDF]
	Clinical Features and Outcome of Primary Effusion Lymphoma in HIV-Infected Patients: A Single-Institution Study
	Cecilia Simonelli, Michele Spina, Roberta Cinelli, Renato Talamini, Rosamaria Tedeschi, Annunziata Gloghini, Emanuela Vaccher, Antonino Carbone, and Umberto Tirelli
	JCO Nov 1 2003: 3948–3954. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Biomarker for the Pharmacological Response of PTK787/ZK 222584, an Inhibitor of the Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, in Patients With Advanced Colorectal Cancer and Liver Metastases: Results From Two Phase I Studies
	Bruno Morgan, Anne L. Thomas, Joachim Drevs, Juergen Hennig, Martin Buchert, Asvina Jivan, Mark A. Horsfield, Klauss Mross, Howard A. Ball, Lucy Lee, William Mietlowski, Stefan Fuxius, Clemens Unger, Ken O’Byrne, Andrew Henry, Graham R. Cherryman, Dirk Laurent, Margaret Dugan, Dieter Marmé, and William P. Steward
	JCO Nov 1 2003: 3955–3964. First published on Sep 29 2003; 10.1200/JCO.2003.08.092. [Abstract] [Full Text] [PDF]
	Pharmacokinetics, Safety, and Efficacy of Trastuzumab Administered Every Three Weeks in Combination With Paclitaxel
	Brian Leyland-Jones, Karen Gelmon, Jean-Pierre Ayoub, Andrew Arnold, Shail Verma, Reg Dias, and Parviz Ghahramani
	JCO Nov 1 2003: 3965–3971. First published on Sep 24 2003; 10.1200/JCO.2003.12.109. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Phase III Trial of Long-Term Adjuvant Androgen Deprivation After Neoadjuvant Hormonal Cytoreduction and Radiotherapy in Locally Advanced Carcinoma of the Prostate: The Radiation Therapy Oncology Group Protocol 92–02
	Gerald E. Hanks, Thomas F. Pajak, Arthur Porter, David Grignon, Harmart Brereton, Varagur Venkatesan, Eric M. Horwitz, Colleen Lawton, Seth A. Rosenthal, Howard M. Sandler, and William U. Shipley
	JCO Nov 1 2003: 3972–3978. [Abstract] [Full Text] [PDF]
	Time Course and Predictors of Symptoms After Primary Prostate Cancer Therapy
	James A. Talcott, Judith Manola, Jack A. Clark, Irving Kaplan, Clair J. Beard, Sonya P. Mitchell, Ronald C. Chen, Michael P. O’Leary, Philip W. Kantoff, and Anthony V. D’Amico
	JCO Nov 1 2003: 3979–3986. [Abstract] [Full Text] [PDF]
	Subcutaneous Interleukin-2 and Interferon Alfa Administration in Patients With Metastatic Renal Cell Carcinoma: Final Results of SCAPP III, a Large, Multicenter, Phase II, Nonrandomized Study With Sequential Analysis Design—The Subcutaneous Administration Propeukin Program Cooperative Group
	Jean-Marc Tourani, Christian Pfister, Nicole Tubiana, Mahmoud Ouldkaci, Gilles Prevot, Virginie Lucas, Stéphane Oudard, Maxime Malet, Paul Cottu, Jean-Marc Ferrero, Didier Mayeur, Olivier Rixe, Xu-Shan Sun, Olivier Bernard, Thierry Andre, Christophe Tournigand, Xavier Muracciole, and Joelle Guilhot
	JCO Nov 1 2003: 3987–3994. [Abstract] [Full Text] [PDF]
	F-18 Fluorodeoxyglucose Positron Emission Tomography in the Evaluation of Distant Metastases From Renal Cell Carcinoma
	Navneet S. Majhail, Jean-Luc Urbain, Justin M. Albani, Mangesh H. Kanvinde, Thomas W. Rice, Andrew C. Novick, Tarek M. Mekhail, Thomas E. Olencki, Paul Elson, and Ronald M. Bukowski
	JCO Nov 1 2003: 3995–4000. [Abstract] [Full Text] [PDF]
	Temporarily Deferred Therapy (watchful waiting) for Men Younger Than 70 Years and With Low-Risk Localized Prostate Cancer in the Prostate-Specific Antigen Era
	Corey A. Carter, Timothy Donahue, Leon Sun, Hongyu Wu, David G. McLeod, Christopher Amling, Raymond Lance, John Foley, Wade Sexton, Leo Kusuda, Andrew Chung, Douglas Soderdahl, Stephen Jackman, and Judd W. Moul
	JCO Nov 1 2003: 4001–4008. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Preoperative Mitomycin, Ifosfamide, and Cisplatin Followed by Esophagectomy in Squamous Cell Carcinoma of the Esophagus: Pathologic Complete Response Induced by Chemotherapy Leads to Long-Term Survival
	S.J. Darnton, V.R. Archer, D.D. Stocken, P.J. Mulholland, A.G. Casson, and D.R. Ferry
	JCO Nov 1 2003: 4009–4015. [Abstract] [Full Text] [PDF]

Immunotherapy
	Clinical and Immunologic Results of a Randomized Phase II Trial of Vaccination Using Four Melanoma Peptides Either Administered in Granulocyte-Macrophage Colony-Stimulating Factor in Adjuvant or Pulsed on Dendritic Cells
	Craig L. Slingluff, Jr, Gina R. Petroni, Galina V. Yamshchikov, Donna L. Barnd, Shannon Eastham, Holly Galavotti, James W. Patterson, Donna H. Deacon, Sarah Hibbitts, David Teates, Patrice Y. Neese, William W. Grosh, Kimberly A. Chianese-Bullock, Elizabeth M.H. Woodson, Catherine J. Wiernasz, Priscilla Merrill, Jennifer Gibson, Maureen Ross, and Victor H. Engelhard
	JCO Nov 1 2003: 4016–4026. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Breast Cancer in Older Women: Quality of Life and Psychosocial Adjustment in the 15 Months After Diagnosis
	Patricia A. Ganz, Edward Guadagnoli, Mary Beth Landrum, Timothy L. Lash, William Rakowski, and Rebecca A. Silliman
	JCO Nov 1 2003: 4027–4033. [Abstract] [Full Text] [PDF]

Prevention
	Bilateral Prophylactic Oophorectomy and Ovarian Cancer Screening Following BRCA1/BRCA2 Mutation Testing
	Marc D. Schwartz, Elizabeth Kaufman, Beth N. Peshkin, Claudine Isaacs, Chanita Hughes, Tiffani DeMarco, Clinton Finch, and Caryn Lerman
	JCO Nov 1 2003: 4034–4041. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLE
	American Society of Clinical Oncology 2003 Update on the Role of Bisphosphonates and Bone Health Issues in Women With Breast Cancer
	Bruce E. Hillner, James N. Ingle, Rowan T. Chlebowski, Julie Gralow, Gary C. Yee, Nora A. Janjan, Jane A. Cauley, Brent A. Blumenstein, Kathy S. Albain, Allan Lipton, and Susan Brown
	JCO Nov 1 2003: 4042–4057. First published on Sep 8 2003; 10.1200/JCO.2003.08.017. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Patients Presenting With CNS Lesions: CASE 1. PRIMARY LOW-GRADE MUCOSA-ASSOCIATED B-CELL LYMPHOMA OF THE DURA

Volney Soares Lima, Ellem Brandão Leite, Roberto Porto Fonseca, and Amândio Soares Fernandes, Jr

JCO Nov 1 2003: 4058–4060. [Full Text] [PDF]

Patients Presenting With CNS Lesions: CASE 2. SUBDURAL PRESENTATION OF RECURRENT BREAST CANCER

J. Lee Villano and Christopher W. Ryan

JCO Nov 1 2003: 4060–4062. [Full Text] [PDF]

Patients Presenting With CNS Lesions: CASE 3. SEQUENTIAL MYELOPROLIFERATIVE DISEASE AND GLIOBLASTOMA MULTIFORME IN A RENAL TRANSPLANT RECIPIENT

W.Y. Au, K.N. Hung, F. Loong, and S.K. Ma

JCO Nov 1 2003: 4062–4063. [Full Text] [PDF]

ART OF ONCOLOGY

Can You Cure Him, for the Baby’s Sake?

Paulette Mehta and John Fetting

JCO Nov 1 2003: 4064–4065. [Full Text] [PDF]

SPECIAL DEPARTMENTS

CORRESPONDENCE

Thymidine Rescue: An Antidote for Pemetrexed-Related Toxicity in the Setting of Acute Renal Failure

Michael Castro

JCO Nov 1 2003: 4066. [Full Text] [PDF]

Corticosteroids Underemployment in Delayed Chemotherapy-Induced Nausea and Emesis With Poor Adherence to American Society of Clinical Oncology Guidelines: Is This a Reasonable Clinical Choice for the Elderly?

Cesare Gridelli, Paolo Maione, and Antonio Rossi

JCO Nov 1 2003: 4066-a–4067. [Full Text] [PDF]

In Reply:

Wilson C. Mertens, Donald J. Higby, David Brown, Regina Parisi, Janice Fitzgerald, Evan M. Benjamin, and Peter K. Lindenauer

JCO Nov 1 2003: 4067–4068. [Full Text] [PDF]

Extravasations of Oxaliplatin

Albrecht Kretzschmar, Daniel Pink, Peter Thuss-Patience, Bernd Dörken, Peter Reichart, and Robert Eckert

JCO Nov 1 2003: 4068–4069. [Full Text] [PDF]

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