EDITORIALS

Mathematics and Oncology: A Match for Life?

Martine J. Piccart-Gebhart

JCO Apr 15 2003: 1425–1428. First published on Feb 13 2003; 10.1200/JCO.2003.12.068. [Full Text] [PDF]

Keratinocyte Growth Factor: Not Yet Ready for Prime Time

Charles L. Loprinzi and James A. Martenson

JCO Apr 15 2003: 1429–1430. [Full Text] [PDF]

ORIGINAL REPORTS
Breast Cancer
	Randomized Trial of Dose-Dense Versus Conventionally Scheduled and Sequential Versus Concurrent Combination Chemotherapy as Postoperative Adjuvant Treatment of Node-Positive Primary Breast Cancer: First Report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741
	Marc L. Citron, Donald A. Berry, Constance Cirrincione, Clifford Hudis, Eric P. Winer, William J. Gradishar, Nancy E. Davidson, Silvana Martino, Robert Livingston, James N. Ingle, Edith A. Perez, John Carpenter, David Hurd, James F. Holland, Barbara L. Smith, Carolyn I. Sartor, Eleanor H. Leung, Jeffrey Abrams, Richard L. Schilsky, Hyman B. Muss, and Larry Norton
	JCO Apr 15 2003: 1431–1439. First published on Feb 13 2003; 10.1200/JCO.2003.09.081. [Abstract] [Full Text] [PDF]
	Provider Delay Among Patients With Breast Cancer in Germany: A Population-Based Study
	Volker Arndt, Til Stürmer, Christa Stegmaier, Hartwig Ziegler, Annelie Becker, and Hermann Brenner
	JCO Apr 15 2003: 1440–1446. [Abstract] [Full Text] [PDF]
	Quality of Non–Breast Cancer Health Maintenance Among Elderly Breast Cancer Survivors
	Craig C. Earle, Harold J. Burstein, Eric P. Winer, and Jane C. Weeks
	JCO Apr 15 2003: 1447–1451. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Randomized Phase I Trial of Recombinant Human Keratinocyte Growth Factor Plus Chemotherapy: Potential Role as Mucosal Protectant
	Neal J. Meropol, Robert A. Somer, John Gutheil, Robert J. Pelley, Manuel R. Modiano, Eric K. Rowinsky, Mace L. Rothenberg, Spencer W. Redding, Cuneyt M. Serdar, Bin Yao, Robert Heard, and Lee S. Rosen
	JCO Apr 15 2003: 1452–1458. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Treatment of Indolent B-Cell Nonfollicular Lymphomas: Final Results of the LL01 Randomized Trial of the Gruppo Italiano per lo Studio dei Linfomi
	Luca Baldini, Maura Brugiatelli, Stefano Luminari, Marco Lombardo, Francesco Merli, Stefano Sacchi, Paolo Gobbi, Marina Liberati, Luigi Cavanna, Mariangela Colombi, Caterina Stelitano, Maria Goldaniga, Fortunato Morabito, Massimo Federico, and Vittorio Silingardi
	JCO Apr 15 2003: 1459–1465. [Abstract] [Full Text] [PDF]
	Apoptotic-Regulatory and Complement-Protecting Protein Expression in Chronic Lymphocytic Leukemia: Relationship to In Vivo Rituximab Resistance
	Rajat Bannerji, Shinichi Kitada, Ian W. Flinn, Michael Pearson, Donn Young, John C. Reed, and John C. Byrd
	JCO Apr 15 2003: 1466–1471. [Abstract] [Full Text] [PDF]
	Cadherin-13, a Mediator of Calcium-Dependent Cell-Cell Adhesion, Is Silenced by Methylation in Chronic Myeloid Leukemia and Correlates With Pretreatment Risk Profile and Cytogenetic Response to Interferon Alfa
	Jose Roman-Gomez, Juan A. Castillejo, Antonio Jimenez, Francisco Cervantes, Concepcion Boque, Lourdes Hermosin, Angel Leon, Albert Grañena, Dolors Colomer, Anabel Heiniger, and Antonio Torres
	JCO Apr 15 2003: 1472–1479. [Abstract] [Full Text] [PDF]
	Allogeneic Stem-Cell Transplantation From Related and Unrelated Donors in Older Patients With Myeloid Leukemia
	Hartmut Bertz, Karin Potthoff, and Jürgen Finke
	JCO Apr 15 2003: 1480–1484. [Abstract] [Full Text] [PDF]

Central Nervous System
	Phase III Study Comparing Three Cycles of Infusional Carmustine and Cisplatin Followed by Radiation Therapy With Radiation Therapy and Concurrent Carmustine in Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme: Eastern Cooperative Oncology Group Trial 2394
	Stuart A. Grossman, Anne O’Neill, Margaret Grunnet, Minesh Mehta, James L. Pearlman, Henry Wagner, Mark Gilbert, Herbert B. Newton, and Richard Hellman
	JCO Apr 15 2003: 1485–1491. [Abstract] [Full Text] [PDF]

Surgical Oncology
	Cancer Patients Seeking a Second Surgical Opinion: Results of a Study on Motives, Needs, and Expectations
	W.A.M. Mellink, A.M.V. Dulmen, Th. Wiggers, P.M.M. Spreeuwenberg, A.M.M. Eggermont, and J.M. Bensing
	JCO Apr 15 2003: 1492–1497. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Phase II Trial of Intravenous CI-1042 in Patients With Metastatic Colorectal Cancer
	Oday Hamid, Mary L. Varterasian, Scott Wadler, J. Randolph Hecht, Al Benson, III, Evanthia Galanis, Margaret Uprichard, Charles Omer, Paul Bycott, Robert C. Hackman, and Anthony F. Shields
	JCO Apr 15 2003: 1498–1504. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Risk Factors for Relapse in Clinical Stage I Nonseminomatous Testicular Germ Cell Tumors: Results of the German Testicular Cancer Study Group Trial
	Peter Albers, Roswitha Siener, Sabine Kliesch, Lothar Weissbach, Susanne Krege, Christoph Sparwasser, Harald Schulze, Axel Heidenreich, Werner de Riese, Volker Loy, Erhard Bierhoff, Christian Wittekind, Rolf Fimmers, and Michael Hartmann
	JCO Apr 15 2003: 1505–1512. [Abstract] [Full Text] [PDF]
	Cardiovascular Disease as a Long-Term Complication of Treatment for Testicular Cancer
	R.A. Huddart, A. Norman, M. Shahidi, A. Horwich, D. Coward, J. Nicholls, and D.P. Dearnaley
	JCO Apr 15 2003: 1513–1523. [Abstract] [Full Text] [PDF]
	Phase II Study of Troxacitabine (BCH-4556) in Patients With Advanced and/or Metastatic Renal Cell Carcinoma: A Trial of the National Cancer Institute of Canada-Clinical Trials Group
	C.A. Townsley, K. Chi, D.S. Ernst, K. Belanger, I. Tannock, G.A. Bjarnason, D. Stewart, R. Goel, J.D. Ruether, L.L. Siu, J. Jolivet, L. McIntosh, L. Seymour, and M.J. Moore
	JCO Apr 15 2003: 1524–1529. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Patterns of Chemotherapy Use for Women With Ovarian Cancer: A Population-Based Study
	Rosemary D. Cress, Cynthia D. O’Malley, Gary S. Leiserowitz, and Sharon L. Campleman
	JCO Apr 15 2003: 1530–1535. [Abstract] [Full Text] [PDF]

Lung Cancer
	Early Change in Patient-Reported Health During Lung Cancer Chemotherapy Predicts Clinical Outcomes Beyond Those Predicted by Baseline Report: Results From Eastern Cooperative Oncology Group Study 5592
	David T. Eton, Diane L. Fairclough, David Cella, Susan E. Yount, Philip Bonomi, and David H. Johnson
	JCO Apr 15 2003: 1536–1543. [Abstract] [Full Text] [PDF]
	Continued Cigarette Smoking by Patients Receiving Concurrent Chemoradiotherapy for Limited-Stage Small-Cell Lung Cancer Is Associated With Decreased Survival
	Gregory M.M. Videtic, Larry W. Stitt, A. Rashid Dar, Walter I. Kocha, Anna T. Tomiak, Pauline T. Truong, Mark D. Vincent, and Edward W. Yu
	JCO Apr 15 2003: 1544–1549. [Abstract] [Full Text] [PDF]
	Phase II Trial of Gemcitabine in Refractory or Relapsed Small-Cell Lung Cancer: Eastern Cooperative Oncology Group Trial 1597
	Gregory A. Masters, Lieven Declerck, Charles Blanke, Alan Sandler, Russell DeVore, Kathy Miller, and David Johnson
	JCO Apr 15 2003: 1550–1555. [Abstract] [Full Text] [PDF]
	Phase II Study of Pemetrexed With and Without Folic Acid and Vitamin B12 as Front-Line Therapy in Malignant Pleural Mesothelioma
	Giorgio V. Scagliotti, Dong-M. Shin, Hedy L. Kindler, Michael J. Vasconcelles, Uwe Keppler, Christian Manegold, Howard Burris, Ulrich Gatzemeier, Johannes Blatter, James T. Symanowski, and James J. Rusthoven
	JCO Apr 15 2003: 1556–1561. [Abstract] [Full Text] [PDF]

Melanoma
	Adjuvant Immunization of HLA-A2–Positive Melanoma Patients With a Modified gp100 Peptide Induces Peptide-Specific CD8+ T-Cell Responses
	John W. Smith, II, Edwin B. Walker, Bernard A. Fox, Daniel Haley, Ketura P. Wisner, Teri Doran, Brenda Fisher, Lisa Justice, William Wood, John Vetto, Holden Maecker, Annemiek Dols, Sybren Meijer, Hong-Ming Hu, Pedro Romero, W. Gregory Alvord, and Walter J. Urba
	JCO Apr 15 2003: 1562–1573. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Presurgical Chemotherapy Compared With Immediate Surgery and Adjuvant Chemotherapy for Nonmetastatic Osteosarcoma: Pediatric Oncology Group Study POG-8651
	Allen M. Goorin, Douglas J. Schwartzentruber, Meenakshi Devidas, Mark C. Gebhardt, Alberto G. Ayala, Michael B. Harris, Lee J. Helman, Holcombe E. Grier, and Michael P. Link
	JCO Apr 15 2003: 1574–1580. [Abstract] [Full Text] [PDF]
	Results of a Randomized Study of Preradiation Chemotherapy Versus Radiotherapy Alone for Nonmetastatic Medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children’s Cancer Study Group PNET-3 Study
	Roger E. Taylor, Clifford C. Bailey, Kath Robinson, Claire L. Weston, David Ellison, James Ironside, Helen Lucraft, Richard Gilbertson, Diana M. Tait, David A. Walker, Barry L. Pizer, John Imeson, and Linda S. Lashford
	JCO Apr 15 2003: 1581–1591. [Abstract] [Full Text] [PDF]
	Disseminated Neuroblastoma in Children Older Than One Year at Diagnosis: Comparable Results With Three Consecutive High-Dose Protocols Adopted by the Italian Co-Operative Group for Neuroblastoma
	Bruno De Bernardi, Brigitte Nicolas, Luca Boni, Paolo Indolfi, Modesto Carli, Luca Cordero di Montezemolo, Alberto Donfrancesco, Andrea Pession, Massimo Provenzi, Andrea di Cataldo, Antonino Rizzo, Gian Paolo Tonini, Sandro Dallorso, Massimo Conte, Claudio Gambini, Alberto Garaventa, Federico Bonetti, Andrea Zanazzo, Paolo D’Angelo, and Paolo Bruzzi
	JCO Apr 15 2003: 1592–1601. [Abstract] [Full Text] [PDF]
	Synovial Sarcoma of Childhood and Adolescence: A Multicenter, Multivariate Analysis of Outcome
	Mehmet Fatih Okcu, Mark Munsell, Joern Treuner, Adrian Mattke, Alberto Pappo, Alvida Cain, Andrea Ferrari, Michela Casanova, Alp Ozkan, and Beverly Raney
	JCO Apr 15 2003: 1602–1611. [Abstract] [Full Text] [PDF]
	Human Granulocyte Colony-Stimulating Factor in Children With High-Risk Acute Lymphoblastic Leukemia: A Children’s Cancer Group Study
	John A. Heath, Peter G. Steinherz, Arnold Altman, Harland Sather, Suresh Jhanwar, Steven Halpern, Richard Pieters, Narayan Shah, Laurel Steinherz, Raymond Tannous, William Terry, and Michael E. Trigg
	JCO Apr 15 2003: 1612–1617. [Abstract] [Full Text] [PDF]

Clinical Trials
	Enrollment of Older Patients in Cancer Treatment Trials in Canada: Why is Age a Barrier?
	Karen W.L. Yee, Joseph L. Pater, Lam Pho, Benny Zee, and Lillian L. Siu
	JCO Apr 15 2003: 1618–1623. [Abstract] [Full Text] [PDF]

REVIEW ARTICLES
	Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment
	A. Giese, R. Bjerkvig, M.E. Berens, and M. Westphal
	JCO Apr 15 2003: 1624–1636. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLES
	Practical Management of Patients With Chronic Myeloid Leukemia Receiving Imatinib
	Michael W.N. Deininger, Stephen G. O’Brien, John M. Ford, and Brian J. Druker
	JCO Apr 15 2003: 1637–1647. First published on Mar 13 2003; 10.1200/JCO.2003.11.143. [Abstract] [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Shorter is not Better

J.N. Munck

JCO Apr 15 2003: 1648. [Full Text] [PDF]

In Reply:

Andrea Ardizzoni

JCO Apr 15 2003: 1648-a–1649. [Full Text] [PDF]

International Collaborative Group Against Primary CNS Lymphomas

Andrés J.M. Ferreri, Tracy Batchelor, Emanuele Zucca, Franco Cavalli, and James Armitage

JCO Apr 15 2003: 1649–1650. [Full Text] [PDF]

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