EDITORIALS

A Rose, Is a Rose, Is a Rose...or Not

Al B. Benson, III and Paul J. Catalano

JCO May 15 2004: 1773–1775. First published on Apr 5 2004; 10.1200/JCO.2004.02.946. [Full Text] [PDF]

Tailoring Breast Cancer Treatment to Genetic Status: The Challenges Ahead

Mary B. Daly

JCO May 15 2004: 1776–1777. First published on Apr 5 2004; 10.1200/JCO.2004.02.994. [Full Text] [PDF]

ORIGINAL REPORTS
Gastrointestinal Cancer
	New Tumor-Node-Metastasis Staging Strategy for Node-Positive (stage III) Rectal Cancer: An Analysis
	Frederick L. Greene, Andrew K. Stewart, and H. James Norton
	JCO May 15 2004: 1778–1784. First published on Feb 9 2004; 10.1200/JCO.2004.07.015. [Abstract] [Full Text] [PDF]
	Impact of T and N Stage and Treatment on Survival and Relapse in Adjuvant Rectal Cancer: A Pooled Analysis
	Leonard L. Gunderson, Daniel J. Sargent, Joel E. Tepper, Norman Wolmark, Michael J. O'Connell, Mirsada Begovic, Cristine Allmer, Linda Colangelo, Steven R. Smalley, Daniel G. Haller, James A. Martenson, Robert J. Mayer, Tyvin A. Rich, Jaffer A. Ajani, John S. MacDonald, Christopher G. Willett, and Richard M. Goldberg
	JCO May 15 2004: 1785–1796. First published on Apr 5 2004; 10.1200/JCO.2004.08.173. [Abstract] [Full Text] [PDF]
	Pooled Analysis of Fluorouracil-Based Adjuvant Therapy for Stage II and III Colon Cancer: Who Benefits and by How Much?
	Sharlene Gill, Charles L. Loprinzi, Daniel J. Sargent, Stephan D. Thomé, Steven R. Alberts, Daniel G. Haller, Jacqueline Benedetti, Guido Francini, Lois E. Shepherd, Jean Francois Seitz, Roberto Labianca, Wei Chen, Stephen S. Cha, Michael P. Heldebrant, and Richard M. Goldberg
	JCO May 15 2004: 1797–1806. First published on Apr 5 2004; 10.1200/JCO.2004.09.059. [Abstract] [Full Text] [PDF]
	Telomere Length and Human Telomerase Reverse Transcriptase Expression As Markers for Progression and Prognosis of Colorectal Carcinoma
	Ralf Gertler, Robert Rosenberg, Dominik Stricker, Jan Friederichs, Axel Hoos, Martin Werner, Kurt Ulm, Bernhard Holzmann, Hjalmar Nekarda, and Joerg-Ruediger Siewert
	JCO May 15 2004: 1807–1814. [Abstract] [Full Text] [PDF]
	Pegylated Arginine Deiminase Treatment of Patients With Unresectable Hepatocellular Carcinoma: Results From Phase I/II Studies
	Francesco Izzo, Paolo Marra, Gerardo Beneduce, Giuseppe Castello, Paolo Vallone, Vincenzo De Rosa, Franco Cremona, C. Mark Ensor, Frederick W. Holtsberg, John S. Bomalaski, Mike A. Clark, Chaan Ng, and Steven A. Curley
	JCO May 15 2004: 1815–1822. [Abstract] [Full Text] [PDF]

Breast Cancer
	Impact of BRCA1/BRCA2 Counseling and Testing on Newly Diagnosed Breast Cancer Patients
	Marc D. Schwartz, Caryn Lerman, Barbara Brogan, Beth N. Peshkin, Chanita Hughes Halbert, Tiffani DeMarco, William Lawrence, David Main, Clinton Finch, Colette Magnant, Marie Pennanen, Theodore Tsangaris, Shawna Willey, and Claudine Isaacs
	JCO May 15 2004: 1823–1829. First published on Apr 5 2004; 10.1200/JCO.2004.04.086. [Abstract] [Full Text] [PDF]
	Quantitative DNA Fingerprinting May Distinguish New Primary Breast Cancer From Disease Recurrence
	Benjamin L. Schlechter, Qiong Yang, Pamela S. Larson, Arina Golubeva, Rita A. Blanchard, Antonio de Las Morenas, and Carol L. Rosenberg
	JCO May 15 2004: 1830–1838. [Abstract] [Full Text] [PDF]
	Prognostic Indicators and Survival in Patients With Stage IIIB Inflammatory Breast Carcinoma After Dose-Intense Chemotherapy
	George Somlo, Paul Frankel, Warren Chow, Lucille Leong, Kim Margolin, Robert Morgan, Jr, Stephen Shibata, Peiguo Chu, Stephen Forman, Dean Lim, Przemyslaw Twardowski, Jeffrey Weitzel, Joseph Alvarnas, Neil Kogut, Jeffrey Schriber, Eleanor Fermin, Yun Yen, Lloyd Damon, and James H. Doroshow
	JCO May 15 2004: 1839–1848. [Abstract] [Full Text] [PDF]
	Functional Impact of Breast Cancer by Age at Diagnosis
	Candyce H. Kroenke, Bernard Rosner, Wendy Y. Chen, Ichiro Kawachi, Graham A. Colditz, and Michelle D. Holmes
	JCO May 15 2004: 1849–1856. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Magnitude of Response With Myeloma Frontline Therapy Does Not Predict Outcome: Importance of Time to Progression in Southwest Oncology Group Chemotherapy Trials
	Brian G.M. Durie, Joth Jacobson, Bart Barlogie, and John Crowley
	JCO May 15 2004: 1857–1863. First published on Apr 26 2004; 10.1200/JCO.2004.05.111. [Abstract] [Full Text] [PDF]
	Subclinical Late Cardiomyopathy After Doxorubicin Therapy for Lymphoma in Adults
	O. Hequet, Q.H. Le, I. Moullet, E. Pauli, G. Salles, D. Espinouse, C. Dumontet, C. Thieblemont, P. Arnaud, D. Antal, F. Bouafia, and B. Coiffier
	JCO May 15 2004: 1864–1871. [Abstract] [Full Text] [PDF]

Lung Cancer
	Results of a Phase II Study of Weekly Paclitaxel Plus Carboplatin in Patients With Extensive Small-Cell Lung Cancer With Eastern Cooperative Oncology Group Performance Status of 2, or Age 70 Years
	Marcus Neubauer, Jonathan Schwartz, John Caracandas, Paul Conkling, Des Ilegbodu, Troy Tuttle, and Lina Asmar
	JCO May 15 2004: 1872–1877. [Abstract] [Full Text] [PDF]
	RRM1 and PTEN As Prognostic Parameters for Overall and Disease-Free Survival in Patients With Non–Small-Cell Lung Cancer
	Gerold Bepler, Swati Sharma, Alan Cantor, Ashish Gautam, Eric Haura, George Simon, Anupama Sharma, Eric Sommers, and Lary Robinson
	JCO May 15 2004: 1878–1885. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Combined Use of Erythropoietin and Granulocyte Colony-Stimulating Factor Does Not Decrease Blood Transfusion Requirements During Induction Therapy for High-Risk Neuroblastoma: A Randomized Controlled Trial
	Lars M. Wagner, Catherine A. Billups, Wayne L. Furman, Bhaskar N. Rao, and Victor M. Santana
	JCO May 15 2004: 1886–1893. [Abstract] [Full Text] [PDF]
	Age Is a Risk Factor for Chemotherapy-Induced Hepatopathy With Vincristine, Dactinomycin, and Cyclophosphamide
	C. Arndt, D. Hawkins, J.R. Anderson, P. Breitfeld, R. Womer, and W. Meyer
	JCO May 15 2004: 1894–1901. [Abstract] [Full Text] [PDF]
	Failure Pattern and Factors Predictive of Local Failure in Rhabdomyosarcoma: A Report of Group III Patients on the Third Intergroup Rhabdomyosarcoma Study
	Moody D. Wharam, Jane Meza, James Anderson, John C. Breneman, Sarah S. Donaldson, Thomas J. Fitzgerald, Jeff Michalski, Lisa A. Teot, Eugene S. Wiener, and William H. Meyer
	JCO May 15 2004: 1902–1908. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Phase I Trial of Weekly Docetaxel With Concurrent Three-Dimensional Conformal Radiation Therapy in the Treatment of Unfavorable Localized Adenocarcinoma of the Prostate
	Parvesh Kumar, Michael Perrotti, Robert Weiss, Mary Todd, Susan Goodin, Kenneth Cummings, and Robert S. DiPaola
	JCO May 15 2004: 1909–1915. [Abstract] [Full Text] [PDF]

Immunotherapy
	Effect of Dose on Immune Response in Patients Vaccinated With an HER-2/neu Intracellular Domain Protein—Based Vaccine
	Mary L. Disis, Kathy Schiffman, Katherine Guthrie, Lupe G. Salazar, Keith L. Knutson, Vivian Goodell, Corazon dela Rosa, and Martin A. Cheever
	JCO May 15 2004: 1916–1925. [Abstract] [Full Text] [PDF]

Neurooncology
	The Prognostic Significance of Phosphatidylinositol 3-Kinase Pathway Activation in Human Gliomas
	Arnab Chakravarti, Gary Zhai, Yoshiyuki Suzuki, Sormeh Sarkesh, Peter M. Black, Alona Muzikansky, and Jay S. Loeffler
	JCO May 15 2004: 1926–1933. [Abstract] [Full Text] [PDF]
	Thiotepa-Based High-Dose Chemotherapy With Autologous Stem-Cell Rescue in Patients With Recurrent or Progressive CNS Germ Cell Tumors
	Shakeel Modak, Sharon Gardner, Ira J. Dunkel, Casilda Balmaceda, Marc K. Rosenblum, Douglas C. Miller, Steven Halpern, and Jonathan L. Finlay
	JCO May 15 2004: 1934–1943. [Abstract] [Full Text] [PDF]

Cancer Related Complications
	Low Molecular Weight Heparin, Therapy With Dalteparin, and Survival in Advanced Cancer: The Fragmin Advanced Malignancy Outcome Study (FAMOUS)
	Ajay K. Kakkar, Mark N. Levine, Zbigniew Kadziola, Nicholas R. Lemoine, Vanessa Low, Heman K. Patel, Gordon Rustin, Michael Thomas, Mary Quigley, and Robin C.N. Williamson
	JCO May 15 2004: 1944–1948. [Abstract] [Full Text] [PDF]
	Diagnosis of Deep Septic Thrombophlebitis in Cancer Patients by Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography Scanning: A Preliminary Report
	Marisa Miceli, Rola Atoui, Ronald Walker, Tahsine Mahfouz, Nadeem Mirza, Jose Diaz, Guido Tricot, Bart Barlogie, and Elias Anaissie
	JCO May 15 2004: 1949–1956. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Major Depression, Adjustment Disorders, and Post-Traumatic Stress Disorder in Terminally Ill Cancer Patients: Associated and Predictive Factors
	Tatsuo Akechi, Toru Okuyama, Yuriko Sugawara, Tomohito Nakano, Yasuo Shima, and Yosuke Uchitomi
	JCO May 15 2004: 1957–1965. [Abstract] [Full Text] [PDF]
	Are Chemotherapy Response Rates Related to Treatment-Induced Survival Prolongations in Patients With Advanced Cancer?
	Tait D. Shanafelt, Charles Loprinzi, Randolph Marks, Paul Novotny, and Jeff Sloan
	JCO May 15 2004: 1966–1974. First published on Apr 26 2004; 10.1200/JCO.2004.08.176. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Nonsteroidal Anti-Inflammatory Drugs, Alone or Combined With Opioids, for Cancer Pain: A Systematic Review
	Ewan McNicol, Scott Strassels, Leonidas Goudas, Joseph Lau, and Daniel Carr
	JCO May 15 2004: 1975–1992. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLES
	Quality of Abstracts Describing Randomized Trials in the Proceedings of American Society of Clinical Oncology Meetings: Guidelines for Improved Reporting
	Monika K. Krzyzanowska, Melania Pintilie, Christine Brezden-Masley, Rebecca Dent, and Ian F. Tannock
	JCO May 15 2004: 1993–1999. [Abstract] [Full Text] [PDF]
	International Assessment of the Quality of Clinical Practice Guidelines in Oncology Using the Appraisal of Guidelines and Research and Evaluation Instrument
	J.S. Burgers, B. Fervers, M. Haugh, M. Brouwers, G. Browman, T. Philip, and F.A. Cluzeau
	JCO May 15 2004: 2000–2007. [Abstract] [Full Text] [PDF]
	Palliative Care Inpatient Service in a Comprehensive Cancer Center: Clinical and Financial Outcomes
	Ahmed Elsayem, Kay Swint, Michael J. Fisch, J. Lynn Palmer, Suresh Reddy, Paul Walker, Donna Zhukovsky, Patti Knight, and Eduardo Bruera
	JCO May 15 2004: 2008–2014. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Epothilones: Mechanism of Action and Biologic Activity
	Susan Goodin, Michael P. Kane, and Eric H. Rubin
	JCO May 15 2004: 2015–2025. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Soft Tissue Sarcomas: CASE 1. Granulocytic Sarcoma: Presentation With Nodal and Skin Involvement

Vinay Raja, Barbara Bryant, David J. Bessman, and Jack B. Alperin

JCO May 15 2004: 2026–2027. [Full Text] [PDF]

Soft Tissue Sarcomas: CASE 2. Orbital Alveolar Soft Part Sarcoma in a Child

Wai-Man Chan, David T.L. Liu, Chris K.C. Lai, Marvin W.Y. Tse, Joan S.K. Ng, and Dennis S.C. Lam

JCO May 15 2004: 2027–2029. [Full Text] [PDF]

Soft Tissue Sarcomas: CASE 3. Gastrointestinal Stromal Tumor and Carney's Triad

Alain Spatz, Brigitte Bressac-de Paillerets, and Eric Raymond

JCO May 15 2004: 2029–2031. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Tumor Rupture and Mitotic Index in Pediatric Sex Cord-Stromal Tumors

James I. Geller and Victor M. Santana

JCO May 15 2004: 2032–2033. [Full Text] [PDF]

In Reply:

Dominik T. Schneider, Gabriele Calaminus, and Ulrich Göbel

JCO May 15 2004: 2033–2035. [Full Text] [PDF]

Pamidronate, Hypocalcemia, and Calcium and Vitamin D Supplementation

Ozden Altundag and Kadri Altundag

JCO May 15 2004: 2035. [Full Text] [PDF]

In Reply:

Eric J. Small

JCO May 15 2004: 2035-a. [Full Text] [PDF]

Molecular Markers to Predict Response to Gefitinib: EGFR, ErbB-2, or More?

Nicola Normanno, Massimo Di Maio, Francesco Perrone, and Manuela Campiglio

JCO May 15 2004: 2035-b–2036. [Full Text] [PDF]

In Reply:

Federico Cappuzzo

JCO May 15 2004: 2036–2037. [Full Text] [PDF]

Errata

Erratum

JCO May 15 2004: 2038. [Full Text] [PDF]

Erratum

JCO May 15 2004: 2038-a. [Full Text] [PDF]

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