EDITORIALS

The Phase III Candidate: Can We Improve the Science of Selection?

Dean Bajorin

JCO Jan 15 2004: 211–213. First published on Dec 9 2003; 10.1200/JCO.2004.10.988. [Full Text] [PDF]

Phase I's, Photons, and Philosophies: New Tactics for Exploratory Clinical Trials of Concurrent Chemoradiation

Mitchell Machtay

JCO Jan 15 2004: 214–216. First published on Dec 9 2003; 10.1200/JCO.2004.11.901. [Full Text] [PDF]

Economics of Preoperative Radiotherapy With Total Mesorectal Excision: What Can We Learn From the Dutch Experience?

Marko Simunovic, Amiram Gafni, and Mark Levine

JCO Jan 15 2004: 217–219. First published on Dec 9 2003; 10.1200/JCO.2004.11.918. [Full Text] [PDF]

ORIGINAL REPORTS
Genitourinary Cancer
	Docetaxel and Cisplatin With Granulocyte Colony-Stimulating Factor (G-CSF) Versus MVAC With G-CSF in Advanced Urothelial Carcinoma: A Multicenter, Randomized, Phase III Study From the Hellenic Cooperative Oncology Group
	A. Bamias, G. Aravantinos, C. Deliveliotis, D. Bafaloukos, C. Kalofonos, N. Xiros, A. Zervas, D. Mitropoulos, E. Samantas, D. Pectasides, P. Papakostas, D. Gika, C. Kourousis, A. Koutras, C. Papadimitriou, C. Bamias, P. Kosmidis, and M.A. Dimopoulos
	JCO Jan 15 2004: 220–228. First published on Dec 9 2003; 10.1200/JCO.2004.02.152. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	FOLFIRI Followed by FOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer: A Randomized GERCOR Study
	Christophe Tournigand, Thierry André, Emmanuel Achille, Gérard Lledo, Michel Flesh, Dominique Mery-Mignard, Emmanuel Quinaux, Corinne Couteau, Marc Buyse, Gérard Ganem, Bruno Landi, Philippe Colin, Christophe Louvet, and Aimery de Gramont
	JCO Jan 15 2004: 229–237. First published on Dec 2 2003; 10.1200/JCO.2004.05.113. [Abstract] [Full Text] [PDF]
	Phase I Trial Using a Time-to-Event Continual Reassessment Strategy for Dose Escalation of Cisplatin Combined With Gemcitabine and Radiation Therapy in Pancreatic Cancer
	Jeffrey H. Muler, Cornelius J. McGinn, Daniel Normolle, Theodore Lawrence, Diane Brown, Gwen Hejna, and Mark M. Zalupski
	JCO Jan 15 2004: 238–243. First published on Dec 9 2003; 10.1200/JCO.2004.03.129. [Abstract] [Full Text] [PDF]

Statistical/Economic Analysis
	Cost-Utility Analysis of Preoperative Radiotherapy in Patients With Rectal Cancer Undergoing Total Mesorectal Excision: A Study of the Dutch Colorectal Cancer Group
	Mandy van den Brink, Wilbert B. van den Hout, Anne M. Stiggelbout, Elma Klein Kranenbarg, Corrie A.M. Marijnen, Cornelis J.H. van de Velde, and Job Kievit
	JCO Jan 15 2004: 244–253. First published on Dec 9 2003; 10.1200/JCO.2004.04.198. [Abstract] [Full Text] [PDF]

Lung Cancer
	Phase III Randomized Trial of Docetaxel Plus Cisplatin Versus Vindesine Plus Cisplatin in Patients With Stage IV Non-Small-Cell Lung Cancer: The Japanese Taxotere Lung Cancer Study Group
	Kaoru Kubota, Koshiro Watanabe, Hideo Kunitoh, Kazumasa Noda, Yukito Ichinose, Nobuyuki Katakami, Takahiko Sugiura, Masaaki Kawahara, Akira Yokoyama, Soichiro Yokota, Shuichi Yoneda, Kaoru Matsui, Shinzo Kudo, Masahiko Shibuya, Takeshi Isobe, Yoshihiko Segawa, Yutaka Nishiwaki, Yasuo Ohashi, and Hisanobu Niitani
	JCO Jan 15 2004: 254–261. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Outcome of Elderly Patients With Recurrent or Metastatic Head and Neck Cancer Treated With Cisplatin-Based Chemotherapy
	Athanassios Argiris, Yi Li, Barbara A. Murphy, Corey J. Langer, and Arlene A. Forastiere
	JCO Jan 15 2004: 262–268. [Abstract] [Full Text] [PDF]

Breast Cancer
	Phase III Study of N,N-Diethyl-2-[4-(Phenylmethyl) Phenoxy]Ethanamine (BMS-217380-01) Combined With Doxorubicin Versus Doxorubicin Alone in Metastatic/Recurrent Breast Cancer: National Cancer Institute of Canada Clinical Trials Group Study MA.19
	Leonard Reyno, Lesley Seymour, Dongsheng Tu, Susan Dent, Karen Gelmon, Barbara Walley, Anna Pluzanska, Vera Gorbunova, Avgust Garin, Jacek Jassem, Tadeusz Pienkowski, Janet Dancey, Laura Pearce, Mary MacNeil, Susan Marlin, David Lebwohl, Maurizio Voi, and Kathleen Pritchard
	JCO Jan 15 2004: 269–276. [Abstract] [Full Text] [PDF]
	Prospective Multicenter Study of Axillary Nodal Staging by Positron Emission Tomography in Breast Cancer: A Report of the Staging Breast Cancer With PET Study Group
	Richard L. Wahl, Barry A. Siegel, R. Edward Coleman, and Constantine G. Gatsonis
	JCO Jan 15 2004: 277–285. [Abstract] [Full Text] [PDF]

Melanoma
	BRAF Gene Is Somatically Mutated but Does Not Make a Major Contribution to Malignant Melanoma Susceptibility: The Italian Melanoma Intergroup Study
	Milena Casula, Maria Colombino, Maria P. Satta, Antonio Cossu, Paolo A. Ascierto, Giovanna Bianchi-Scarrà, Daniele Castiglia, Mario Budroni, Carla Rozzo, Antonella Manca, Amelia Lissia, Annangela Carboni, Elisabetta Petretto, Sabrina M.R. Satriano, Gerardo Botti, Michela Mantelli, Paola Ghiorzo, Michael R. Stratton, Francesco Tanda, and Giuseppe Palmieri
	JCO Jan 15 2004: 286–292. [Abstract] [Full Text] [PDF]

Thoracic Oncology
	Octreotide Alone or With Prednisone in Patients With Advanced Thymoma and Thymic Carcinoma: An Eastern Cooperative Oncology Group Phase II Trial
	Patrick J. Loehrer, Sr, Wei Wang, David H. Johnson, and David S. Ettinger
	JCO Jan 15 2004: 293–299. [Abstract] [Full Text] [PDF]

Pain Management
	Percutaneous Image-Guided Radiofrequency Ablation of Painful Metastases Involving Bone: A Multicenter Study
	Matthew P. Goetz, Matthew R. Callstrom, J. William Charboneau, Michael A. Farrell, Timothy P. Maus, Timothy J. Welch, Gilbert Y. Wong, Jeff A. Sloan, Paul J. Novotny, Ivy A. Petersen, Robert A. Beres, Daniele Regge, Rodolfo Capanna, Mark B. Saker, Dietrich H.W. Grönemeyer, Athour Gevargez, Kamran Ahrar, Michael A. Choti, Thierry J. de Baere, and Joseph Rubin
	JCO Jan 15 2004: 300–306. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	The Attitudes of Cancer Patients and Their Families Toward the Disclosure of Terminal Illness
	Young Ho Yun, Chang Geol Lee, Si-young Kim, Sang-wook Lee, Dae Seog Heo, Jun Suk Kim, Keun Seok Lee, Young Seon Hong, Jung Suk Lee, and Chang Hoon You
	JCO Jan 15 2004: 307–314. [Abstract] [Full Text] [PDF]
	Trends in the Aggressiveness of Cancer Care Near the End of Life
	Craig C. Earle, Bridget A. Neville, Mary Beth Landrum, John Z. Ayanian, Susan D. Block, and Jane C. Weeks
	JCO Jan 15 2004: 315–321. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Clinical Cardiac Tolerability of Trastuzumab
	Edith A. Perez and Richard Rodeheffer
	JCO Jan 15 2004: 322–329. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLE

American Society of Clinical Oncology Treatment of Unresectable Non–Small-Cell Lung Cancer Guideline: Update 2003

David G. Pfister, David H. Johnson, Christopher G. Azzoli, William Sause, Thomas J. Smith, Sherman Baker, Jr, Jemi Olak, Diane Stover, John R. Strawn, Andrew T. Turrisi, and Mark R. Somerfield

JCO Jan 15 2004: 330–353. First published on Dec 22 2003; 10.1200/JCO.2004.09.053. [Full Text] [PDF]

SPECIAL ARTICLE
	Quality of Life Among Disease-Free Survivors of Rectal Cancer
	Philippe Rauch, Joelle Miny, Thierry Conroy, Lionel Neyton, and Francis Guillemin
	JCO Jan 15 2004: 354–360. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	The Role of Signal Transducer and Activator of Transcription Factors in Leukemogenesis
	David W. Sternberg and D. Gary Gilliland
	JCO Jan 15 2004: 361–371. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Complications of Malignancy: CASE 1. Systemic Tumor Embolism From Lung Cancer at Presentation

Eyad Al-Thenayan and Irfan Maghfoor

JCO Jan 15 2004: 372–373. [Full Text] [PDF]

Complications of Malignancy: CASE 2. Infectious Tissue Pneumatosis As a Result of Colon Cancer Perforation in a Survivor of Hodgkin's Disease

Roderich E. Schwarz and Roger K. Strair

JCO Jan 15 2004: 373–374. [Full Text] [PDF]

Complications of Malignancy: CASE 3. Chronic Lymphocytic Leukemia Presenting With Panhypopituitarism

S. Nimubona, M. Bernard, P. Morice, G. Brassier, S. Caulet-Maugendre, B. Carsin, C. Meunier, and T. Lamy

JCO Jan 15 2004: 374–376. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Cisplatin and Fluorouracil Concurrent to Radiotherapy in Nasopharyngeal Cancer: Is the Schedule Compatible?

Lisa Licitra, Paolo Bossi, Laura Locati, and Franco Zunino

JCO Jan 15 2004: 377. [Full Text] [PDF]

In Reply:

Jin-Ching Lin and Jian-Sheng Jan

JCO Jan 15 2004: 377-a–378. [Full Text] [PDF]

What Is "Appropriate" Care for Ovarian Cancer?

Donald W. Wiper

JCO Jan 15 2004: 378–379. [Full Text] [PDF]

In Reply:

Rosemary D. Cress and Gary S. Leiserowitz

JCO Jan 15 2004: 379. [Full Text] [PDF]

The Prognostic Significance of Indium-111–Capromab Penetide

D.B. Sodee, P.F. Faulhaber, A.D. Nelson, and G. Bakale

JCO Jan 15 2004: 379-a–380. [Full Text] [PDF]

In Reply:

Cherry T. Thomas, Parick T. Bradshaw, Brad H. Pollock, James E. Montie, Jeremy M.G. Taylor, Howard D. Thames, Patrick W. McLaughlin, David A. DeBiose, David H. Hussey, and Richard L. Wahl

JCO Jan 15 2004: 380–381. [Full Text] [PDF]

Inflammatory Breast Carcinoma: The Sphinx of Breast Cancer Research

Massimo Cristofanilli, Eva S. Singletary, and Gabriel N. Hortobagyi

JCO Jan 15 2004: 381–383. [Full Text] [PDF]

In Reply:

William F. Anderson, Kenneth C. Chu, and Shine Chang

JCO Jan 15 2004: 383. [Full Text] [PDF]

Water Intake and Cancer Prevention

Yair Bar David, Benjamin Gesundheit, Jacob Urkin, and Joseph Kapelushnik

JCO Jan 15 2004: 383-a–385. [Full Text] [PDF]

Errata

Erratum for Volume 21, pg. 3972

JCO Jan 15 2004: 386. [Full Text] [PDF]

Erratum for Volume 21, pg. 4423

JCO Jan 15 2004: 386-a. [Full Text] [PDF]

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