EDITORIALS

Concurrent Radiation Chemotherapy for Locally Advanced Head and Neck Carcinoma: Are We Addressing Burning Subjects?

K. Kian Ang

JCO Dec 1 2004: 4657–4659. First published on Nov 8 2004; 10.1200/JCO.2004.07.962. [Full Text] [PDF]

Adjuvant Chemotherapy for Elderly Women With Hormone Receptor-Positive Breast Cancer: An Old(er) Problem

Anne Schott and Daniel F. Hayes

JCO Dec 1 2004: 4660–4662. First published on Oct 25 2004; 10.1200/JCO.2004.07.961. [Full Text] [PDF]

Profiling the Perpetrator

Beth Karlan

JCO Dec 1 2004: 4663–4664. First published on Oct 25 2004; 10.1200/JCO.2004.08.965. [Full Text] [PDF]

ORIGINAL REPORTS
Head and Neck Cancer
	Concomitant Cisplatin Significantly Improves Locoregional Control in Advanced Head and Neck Cancers Treated With Hyperfractionated Radiotherapy
	Pia Huguenin, Karl T. Beer, Abdelkarim Allal, Kaspar Rufibach, Corinne Friedli, Jacques Bernard Davis, Bernhard Pestalozzi, Stephan Schmid, Armin Thöni, Mahmut Ozsahin, Jacques Bernier, Michael Töpfer, Roger Kann, Urs Richard Meier, Peter Thum, Sabine Bieri, Markus Notter, Norbert Lombriser, and Christoph Glanzmann
	JCO Dec 1 2004: 4665–4673. First published on Nov 8 2004; 10.1200/JCO.2004.12.193. [Abstract] [Full Text] [PDF]

Breast Cancer
	Disease-Free Survival Advantage of Weekly Epirubicin Plus Tamoxifen Versus Tamoxifen Alone As Adjuvant Treatment of Operable, Node-Positive, Elderly Breast Cancer Patients: 6-Year Follow-Up Results of the French Adjuvant Study Group 08 Trial
	Pierre Fargeot, Jacques Bonneterre, Henri Roché, Alain Lortholary, Mario Campone, Isabelle Van Praagh, Alain Monnier, Moïse Namer, Simon Schraub, Jean-Claude Barats, Jean-Paul Guastalla, Marie-Josèphe Goudier, and Isabelle Chapelle-Marcillac
	JCO Dec 1 2004: 4674–4682. First published on Oct 25 2004; 10.1200/JCO.2004.02.145. [Abstract] [Full Text] [PDF]
	Randomized Phase III Trial of Marimastat Versus Placebo in Patients With Metastatic Breast Cancer Who Have Responding or Stable Disease After First-Line Chemotherapy: Eastern Cooperative Oncology Group Trial E2196
	Joseph A. Sparano, Patricia Bernardo, Patricia Stephenson, William J. Gradishar, James N. Ingle, Stanley Zucker, and Nancy E. Davidson
	JCO Dec 1 2004: 4683–4690. [Abstract] [Full Text] [PDF]
	Postmastectomy Radiation Improves Local-Regional Control and Survival for Selected Patients With Locally Advanced Breast Cancer Treated With Neoadjuvant Chemotherapy and Mastectomy
	Eugene H. Huang, Susan L. Tucker, Eric A. Strom, Marsha D. McNeese, Henry M. Kuerer, Aman U. Buzdar, Vicente Valero, George H. Perkins, Naomi R. Schechter, Kelly K. Hunt, Aysegul A. Sahin, Gabriel N. Hortobagyi, and Thomas A. Buchholz
	JCO Dec 1 2004: 4691–4699. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Gene Expression Signature With Independent Prognostic Significance in Epithelial Ovarian Cancer
	Dimitrios Spentzos, Douglas A. Levine, Marco F. Ramoni, Marie Joseph, Xuesong Gu, Jeff Boyd, Towia. A. Libermann, and Stephen A. Cannistra
	JCO Dec 1 2004: 4700–4710. First published on Oct 25 2004; 10.1200/JCO.2004.04.070. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Prolonged Clinical and Molecular Remission in Patients With Low-Grade or Follicular Non-Hodgkin's Lymphoma Treated With Rituximab Plus CHOP Chemotherapy: 9-Year Follow-Up
	Myron S. Czuczman, Robin Weaver, Baha Alkuzweny, Judy Berlfein, and Antonio J. Grillo-López
	JCO Dec 1 2004: 4711–4716. First published on Oct 13 2004; 10.1200/JCO.2004.04.020. [Abstract] [Full Text] [PDF]
	Clinical Outcome of Lymphoma Patients After Idiotype Vaccination Is Correlated With Humoral Immune Response and Immunoglobulin G Fc Receptor Genotype
	Wen-Kai Weng, Debra Czerwinski, John Timmerman, Frank J. Hsu, and Ronald Levy
	JCO Dec 1 2004: 4717–4724. First published on Oct 13 2004; 10.1200/JCO.2004.06.003. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Racial Disparity of Epidermal Growth Factor Receptor Expression in Prostate Cancer
	Brian Shuch, Maryann Mikhail, Jaya Satagopan, Peng Lee, Herman Yee, Caroline Chang, Carlos Cordon-Cardo, Samir S. Taneja, and Iman Osman
	JCO Dec 1 2004: 4725–4729. [Abstract] [Full Text] [PDF]

Clinical Trials
	Recruitment of Patients Into an Internet-Based Clinical Trials Database: The Experience of OncoLink and the National Colorectal Cancer Research Alliance
	S.J. Wei, J.M. Metz, C. Coyle, M. Hampshire, H.A. Jones, S. Markowitz, and A.K. Rustgi
	JCO Dec 1 2004: 4730–4736. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Copy Number of Chromosome 17 but Not HER2 Amplification Predicts Clinical Outcome of Patients With Pancreatic Ductal Adenocarcinoma
	Nikolas H. Stoecklein, Andreas M. Luebke, Andreas Erbersdobler, Wolfram T. Knoefel, Winfried Schraut, Pablo E. Verde, Franziska Stern, Peter Scheunemann, Matthias Peiper, Claus F. Eisenberger, Jakob R. Izbicki, Christoph A. Klein, and Stefan B. Hosch
	JCO Dec 1 2004: 4737–4745. [Abstract] [Full Text] [PDF]
	Allele 2 of the Interleukin-1 Receptor Antagonist Gene Is Associated With Early Gastric Cancer
	Jürgen Glas, Helga-Paula Török, Agnes Schneider, Günter Brünnler, Reinhard Kopp, Ekkehard D. Albert, Manfred Stolte, and Christian Folwaczny
	JCO Dec 1 2004: 4746–4752. [Abstract] [Full Text] [PDF]
	Randomized Multicenter Phase II Trial of Bolus Plus Infusional Fluorouracil/Leucovorin Compared With Fluorouracil/Leucovorin Plus Oxaliplatin As Third-Line Treatment of Patients With Advanced Colorectal Cancer
	Nancy Kemeny, Carlos A. Garay, Jayne Gurtler, Howard Hochster, Peter Kennedy, Al Benson, Debra Schwab Brandt, Jonathan Polikoff, Michael Wertheim, Grace Shumaker, Doreen Hallman, Brent Burger, and Sunil Gupta
	JCO Dec 1 2004: 4753–4761. [Abstract] [Full Text] [PDF]
	Fluorouracil, Doxorubicin, and Streptozocin in the Treatment of Patients With Locally Advanced and Metastatic Pancreatic Endocrine Carcinomas
	Maria A. Kouvaraki, Jaffer A. Ajani, Paulo Hoff, Robert Wolff, Douglas B. Evans, Richard Lozano, and James C. Yao
	JCO Dec 1 2004: 4762–4771. [Abstract] [Full Text] [PDF]
	Epidermal Growth Factor Receptor (EGFR) Status in Primary Colorectal Tumors Does Not Correlate With EGFR Expression in Related Metastatic Sites: Implications for Treatment With EGFR-Targeted Monoclonal Antibodies
	Mario Scartozzi, Italo Bearzi, Rossana Berardi, Alessandra Mandolesi, Guidalberto Fabris, and Stefano Cascinu
	JCO Dec 1 2004: 4772–4778. [Abstract] [Full Text] [PDF]

Neurooncology
	Second-Line Chemotherapy With Irinotecan Plus Carmustine in Glioblastoma Recurrent or Progressive After First-Line Temozolomide Chemotherapy: A Phase II Study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)
	Alba A. Brandes, Alicia Tosoni, Umberto Basso, Michele Reni, Francesco Valduga, Silvio Monfardini, Pietro Amistà, Linda Nicolardi, Guido Sotti, and Mario Ermani
	JCO Dec 1 2004: 4779–4786. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	European Intergroup Studies (MMT4-89 and MMT4-91) on Childhood Metastatic Rhabdomyosarcoma: Final Results and Analysis of Prognostic Factors
	M. Carli, R. Colombatti, O. Oberlin, G. Bisogno, J. Treuner, E. Koscielniak, G. Tridello, A. Garaventa, R. Pinkerton, and M. Stevens
	JCO Dec 1 2004: 4787–4794. [Abstract] [Full Text] [PDF]
	Short-Term Efficacy of Methylphenidate: A Randomized, Double-Blind, Placebo-Controlled Trial Among Survivors of Childhood Cancer
	Raymond K. Mulhern, Raja B. Khan, Stuart Kaplan, Susan Helton, Robbin Christensen, Melanie Bonner, Ronald Brown, Xiaoping Xiong, Sengjie Wu, Sridharan Gururangan, and Wilburn E. Reddick
	JCO Dec 1 2004: 4795–4803. [Abstract] [Full Text] [PDF]
	Phase I Study of the Proteasome Inhibitor Bortezomib in Pediatric Patients With Refractory Solid Tumors: A Children's Oncology Group Study (ADVL0015)
	Susan M. Blaney, Mark Bernstein, Kathleen Neville, Jill Ginsberg, Brenda Kitchen, Terzah Horton, Stacey L. Berg, Mark Krailo, and Peter C. Adamson
	JCO Dec 1 2004: 4804–4809. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Complementary and Alternative Medicine Use by Patients Enrolled Onto Phase I Clinical Trials
	Grace K. Dy, Lishan Bekele, Lorelei J. Hanson, Alfred Furth, Sumithra Mandrekar, Jeff A. Sloan, and Alex A. Adjei
	JCO Dec 1 2004: 4810–4815. [Abstract] [Full Text] [PDF]
	Dose-Ranging Pharmacodynamic Study of Tipifarnib (R115777) in Patients With Relapsed and Refractory Hematologic Malignancies
	Todd M. Zimmerman, Helena Harlin, Olatoyosi M. Odenike, Seth Berk, Evie Sprague, Theodore Karrison, Wendy Stock, Richard A. Larson, Mark J. Ratain, and Thomas F. Gajewski
	JCO Dec 1 2004: 4816–4822. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Diagnostic Accuracy of the Palliative Prognostic Score in Hospitalized Patients With Advanced Cancer
	Paul A. Glare, Steffen Eychmueller, and Patrick McMahon
	JCO Dec 1 2004: 4823–4828. [Abstract] [Full Text] [PDF]
	Quality of Life in Patients With Colorectal Cancer 1 Year After Diagnosis Compared With the General Population: A Population-Based Study
	Volker Arndt, Henrike Merx, Christa Stegmaier, Hartwig Ziegler, and Hermann Brenner
	JCO Dec 1 2004: 4829–4836. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Systematic Review Evaluating the Timing of Thoracic Radiation Therapy in Combined Modality Therapy for Limited-Stage Small-Cell Lung Cancer
	Daniel B. Fried, David E. Morris, Charles Poole, Julian G. Rosenman, Jan S. Halle, Frank C. Detterbeck, Thomas A. Hensing, and Mark A. Socinski
	JCO Dec 1 2004: 4837–4845. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLE
	Tissue Collection for Correlative Studies in Childhood Cancer Clinical Trials: Ethical Considerations and Special Imperatives
	Barry D. Anderson, Peter C. Adamson, Susan L. Weiner, Mary S. McCabe, and Malcolm A. Smith
	JCO Dec 1 2004: 4846–4850. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Uncommon Presentations of Cancer Patients: CASE 1. Metastatic Breast Cancer Presenting With Panhypopituitarism

Hasnain M. Khandwala, Deepu Mirchandani, Rajni Chibbar, and Vance Chow

JCO Dec 1 2004: 4851–4853. [Full Text] [PDF]

Uncommon Presentations of Cancer Patients: CASE 2. Colon Cancer Presenting With Intestinal Intussusception

Deri Lewis, Todd M. McCarty, Joseph A. Kuhn, and Jeffrey P. Lamont

JCO Dec 1 2004: 4853–4854. [Full Text] [PDF]

Uncommon Presentations of Cancer Patients: CASE 3. Positron Emission Tomography-Computed Tomgraphy Diagnosis of Metastatic Melanoma With Intussusception

Seza A. Gulec, Mark Beller, Keith Edwards, Paul Lizotte, and Steven O’Day

JCO Dec 1 2004: 4854–4855. [Full Text] [PDF]

ART OF ONCOLOGY

Addressing Spiritual Care: Calling for Help

C. John Steer and Chris Lee

JCO Dec 1 2004: 4856–4858. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Get the Facts Straight

Daniel B. Kopans

JCO Dec 1 2004: 4859. [Full Text] [PDF]

Delayed Benefit of Mammography Screening in Premenopausal Women

Ismail Jatoi, Peter W. Soballe, and William F. Anderson

JCO Dec 1 2004: 4860. [Full Text] [PDF]

In Reply:

Romano Demicheli, Gianni Bonadonna, Pinuccia Valagussa, William J.M. Hrushesky, and Michael W. Retsky

JCO Dec 1 2004: 4860-a–4862. [Full Text] [PDF]

Errata

ERRATA

JCO Dec 1 2004: 4863. [Full Text] [PDF]

ERRATA

JCO Dec 1 2004: 4863-a. [Full Text] [PDF]

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