EDITORIALS

Radiation Therapy and Tamoxifen: Concurrent or Sequential? That Is the Question

Timothy Whelan and Mark Levine

JCO Jan 1 2005: 1–4. First published on Nov 15 2004; 10.1200/JCO.2005.08.955. [Full Text] [PDF]

Chemotherapy and Radiation Therapy for Breast Cancer: What Is the Optimal Sequence?

Jennifer R. Bellon and Jay R. Harris

JCO Jan 1 2005: 5–7. First published on Nov 15 2004; 10.1200/JCO.2005.09.962. [Full Text] [PDF]

Targeted Therapy With Imatinib: Hits and Misses?

Margaret von Mehren

JCO Jan 1 2005: 8–10. First published on Nov 15 2004; 10.1200/JCO.2005.09.961. [Full Text] [PDF]

ORIGINAL REPORTS
Breast Cancer
	Impact of Concurrent Versus Sequential Tamoxifen With Radiation Therapy in Early-Stage Breast Cancer Patients Undergoing Breast Conservation Treatment
	Eleanor E.R. Harris, Vasthi J. Christensen, Wei-Ting Hwang, Kevin Fox, and Lawrence J. Solin
	JCO Jan 1 2005: 11–16. First published on Nov 15 2004; 10.1200/JCO.2005.09.056. [Abstract] [Full Text] [PDF]
	Sequence of Radiotherapy With Tamoxifen in Conservatively Managed Breast Cancer Does Not Affect Local Relapse Rates
	Peter H. Ahn, Ha Thanh Vu, Donald Lannin, Edward Obedian, Michael P. DiGiovanna, Barbara Burtness, and Bruce G. Haffty
	JCO Jan 1 2005: 17–23. First published on Nov 15 2004; 10.1200/JCO.2005.09.048. [Abstract] [Full Text] [PDF]
	Sequencing of Tamoxifen and Radiotherapy After Breast-Conserving Surgery in Early-Stage Breast Cancer
	Lori J. Pierce, Laura F. Hutchins, Stephanie R. Green, Danika L. Lew, Julie R. Gralow, Robert B. Livingston, C. Kent Osborne, and Kathy S. Albain
	JCO Jan 1 2005: 24–29. First published on Nov 15 2004; 10.1200/JCO.2005.01.198. [Abstract] [Full Text] [PDF]
	Effect of Addition of Adjuvant Paclitaxel on Radiotherapy Delivery and Locoregional Control of Node-Positive Breast Cancer: Cancer and Leukemia Group B 9344
	Carolyn I. Sartor, Bercedis L. Peterson, Susan Woolf, Thomas J. FitzGerald, Frances Laurie, Andrew J. Turrisi, Jeff Bogart, I. Craig Henderson, and Larry Norton
	JCO Jan 1 2005: 30–40. First published on Nov 15 2004; 10.1200/JCO.2005.12.044. [Abstract] [Full Text] [PDF]
	Invasive Lobular Carcinoma Classic Type: Response to Primary Chemotherapy and Survival Outcomes
	Massimo Cristofanilli, Ana Gonzalez-Angulo, Nour Sneige, Shu-Wan Kau, Kristine Broglio, Richard L. Theriault, Vicente Valero, Aman U. Buzdar, Henry Kuerer, Thomas A. Buccholz, and Gabriel N. Hortobagyi
	JCO Jan 1 2005: 41–48. [Abstract] [Full Text] [PDF]

Molecular Oncology
	KIT and Platelet-Derived Growth Factor Receptor Alpha Tyrosine Kinase Gene Mutations and KIT Amplifications in Human Solid Tumors
	Harri Sihto, Maarit Sarlomo-Rikala, Olli Tynninen, Minna Tanner, Leif C. Andersson, Kaarle Franssila, Nina N. Nupponen, and Heikki Joensuu
	JCO Jan 1 2005: 49–57. First published on Nov 15 2004; 10.1200/JCO.2005.02.093. [Abstract] [Full Text] [PDF]
	Gene Expression Profiling in Seminoma and Nonseminoma
	M. Port, H.U. Schmelz, M. Stockinger, C. Sparwasser, P. Albers, T. Pottek, and M. Abend
	JCO Jan 1 2005: 58–69. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Detection of Liver Metastases From Endocrine Tumors: A Prospective Comparison of Somatostatin Receptor Scintigraphy, Computed Tomography, and Magnetic Resonance Imaging
	Clarisse Dromain, Thierry de Baere, Jean Lumbroso, Hubert Caillet, Agnès Laplanche, Valerie Boige, Michel Ducreux, Pierre Duvillard, Dominique Elias, Martin Schlumberger, Robert Sigal, and Eric Baudin
	JCO Jan 1 2005: 70–78. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Tirapazamine, Cisplatin, and Radiation Versus Fluorouracil, Cisplatin, and Radiation in Patients With Locally Advanced Head and Neck Cancer: A Randomized Phase II Trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02)
	Danny Rischin, Lester Peters, Richard Fisher, Andrew Macann, Jim Denham, Michael Poulsen, Michael Jackson, Lizbeth Kenny, Michael Penniment, June Corry, David Lamb, and Bev McClure
	JCO Jan 1 2005: 79–87. [Abstract] [Full Text] [PDF]
	Organ Preservation for Advanced Resectable Cancer of the Base of Tongue and Hypopharynx: A Southwest Oncology Group Trial
	Susan G. Urba, James Moon, P.G. Shankar Giri, David J. Adelstein, Ehab Hanna, George H. Yoo, Michael LeBlanc, John F. Ensley, and David E. Schuller
	JCO Jan 1 2005: 88–95. [Abstract] [Full Text] [PDF]

Sarcomas
	Status of Surgical Margins and Prognosis in Adult Soft Tissue Sarcomas of the Extremities: A Series of Patients Treated at a Single Institution
	A. Gronchi, P.G. Casali, L. Mariani, R. Miceli, M. Fiore, S. Lo Vullo, R. Bertulli, P. Collini, L. Lozza, P. Olmi, and J. Rosai
	JCO Jan 1 2005: 96–104. [Abstract] [Full Text] [PDF]
	Randomized Phase II Evaluation of 6 g/m2 of Ifosfamide Plus Doxorubicin and Granulocyte Colony-Stimulating Factor (G-CSF) Compared With 12 g/m2 of Ifosfamide Plus Doxorubicin and G-CSF in the Treatment of Poor-Prognosis Soft Tissue Sarcoma
	Francis P. Worden, Jeremy M.G. Taylor, Janet S. Biermann, Vernon K. Sondak, Kirstin M. Leu, Rashmi Chugh, Cornelius J. McGinn, Mark M. Zalupski, and Laurence H. Baker
	JCO Jan 1 2005: 105–112. [Abstract] [Full Text] [PDF] [Publisher's Note]

Clinical Practice
	Practitioners As Experts: The Influence of Practicing Oncologists "in-the-Field" on Evidence-Based Guideline Development
	George P. Browman, Julie Makarski, Paula Robinson, and Melissa Brouwers
	JCO Jan 1 2005: 113–119. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Autologous and Allogeneic Stem-Cell Transplantation As Salvage Treatment of Acute Promyelocytic Leukemia Initially Treated With All-Trans-Retinoic Acid: A Retrospective Analysis of the European Acute Promyelocytic Leukemia Group
	S. de Botton, A. Fawaz, S. Chevret, H. Dombret, X. Thomas, M. Sanz, A. Guerci, J. San Miguel, J. de la Serna, A.M. Stoppa, O. Reman, A. Stamatoulas, M. Fey, J.Y. Cahn, J.J. Sotto, J.H. Bourhis, A. Parry, C. Chomienne, L. Degos, and P. Fenaux
	JCO Jan 1 2005: 120–126. First published on Nov 8 2004; 10.1200/JCO.2005.03.127. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Risk-Reducing Salpingo-Oophorectomy in BRCA Mutation Carriers: Role of Serial Sectioning in the Detection of Occult Malignancy
	C. Bethan Powell, Eric Kenley, Lee-may Chen, Beth Crawford, Jane McLennan, Charles Zaloudek, Miriam Komaromy, Mary Beattie, and John Ziegler
	JCO Jan 1 2005: 127–132. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Randomized Phase III Trial of High-Dose Interleukin-2 Versus Subcutaneous Interleukin-2 and Interferon in Patients With Metastatic Renal Cell Carcinoma
	David F. McDermott, Meredith M. Regan, Joseph I. Clark, Lawrence E. Flaherty, Geoffery R. Weiss, Theodore F. Logan, John M. Kirkwood, Michael S. Gordon, Jeffrey A. Sosman, Marc S. Ernstoff, Christopher P.G. Tretter, Walter J. Urba, John W. Smith, Kim A. Margolin, James W. Mier, Jared A. Gollob, Janice P. Dutcher, and Michael B. Atkins
	JCO Jan 1 2005: 133–141. [Abstract] [Full Text] [PDF]

Lung Cancer
	Gemcitabine Plus Carboplatin Versus Mitomycin, Ifosfamide, and Cisplatin in Patients With Stage IIIB or IV Non-Small-Cell Lung Cancer: A Phase III Randomized Study of the London Lung Cancer Group
	R.M. Rudd, N.H. Gower, S.G. Spiro, T.G. Eisen, P.G. Harper, J.A.H. Littler, M. Hatton, P.W.M. Johnson, W.M.C. Martin, E.M. Rankin, L.E. James, W.M. Gregory, W. Qian, and S.M. Lee
	JCO Jan 1 2005: 142–153. [Abstract] [Full Text] [PDF]
	Wild-Type p53 Overexpression and Its Correlation With MDM2 and p14ARF Alterations: An Alternative Pathway to Non–Small-Cell Lung Cancer
	Yu-Chien Wang, Ruo-Kai Lin, Yi-Hung Tan, Jung-Ta Chen, Chih-Yi Chen, and Yi-Ching Wang
	JCO Jan 1 2005: 154–164. [Abstract] [Full Text] [PDF]
	Practical Management of Patients With Non–Small-Cell Lung Cancer Treated With Gefitinib
	Neelam T. Shah, Mark G. Kris, William Pao, Leslie B. Tyson, Barbara M. Pizzo, Murk-Hein Heinemann, Leah Ben-Porat, Dana L. Sachs, Robert T. Heelan, and Vincent A. Miller
	JCO Jan 1 2005: 165–174. First published on Nov 22 2004; 10.1200/JCO.2005.04.057. [Abstract] [Full Text] [PDF]
	Clinical Model to Predict Survival in Chemonaive Patients With Advanced Non–Small-Cell Lung Cancer Treated With Third-Generation Chemotherapy Regimens Based on Eastern Cooperative Oncology Group Data
	Tien Hoang, Ronghui Xu, Joan H. Schiller, Philip Bonomi, and David H. Johnson
	JCO Jan 1 2005: 175–183. [Abstract] [Full Text] [PDF]
	Statistical Validation of the EORTC Prognostic Model for Malignant Pleural Mesothelioma Based on Three Consecutive Phase II Trials
	Dean A. Fennell, Amit Parmar, Jonathan Shamash, Marie T. Evans, Michael T. Sheaff, Richard Sylvester, Kevin Dhaliwal, Nicole Gower, Jeremy Steele, and Robin Rudd
	JCO Jan 1 2005: 184–189. [Abstract] [Full Text] [PDF]
	Single-Agent Versus Combination Chemotherapy in Advanced Non–Small-Cell Lung Cancer: The Cancer and Leukemia Group B (study 9730)
	Rogerio C. Lilenbaum, James E. Herndon, II, Marcy A. List, Chris Desch, Dorothy M. Watson, Antonius A. Miller, Stephen L. Graziano, Michael C. Perry, Wayne Saville, Philippe Chahinian, Jane C. Weeks, Jimmie C. Holland, and Mark R. Green
	JCO Jan 1 2005: 190–196. [Abstract] [Full Text] [PDF]

Treatment-Related Complications
	Malignant Breast Tumors After Radiotherapy for a First Cancer During Childhood
	Catherine Guibout, Elisabeth Adjadj, Carole Rubino, Akthar Shamsaldin, Emmanuel Grimaud, Mike Hawkins, Marie-Christine Mathieu, Odile Oberlin, Jean-Michel Zucker, Xavier Panis, Jean-Léon Lagrange, Nicolas Daly-Schveitzer, Jean Chavaudra, and Florent de Vathaire
	JCO Jan 1 2005: 197–204. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Tumoral Drug Metabolism: Overview and Its Implications for Cancer Therapy
	M. Michael and M.M. Doherty
	JCO Jan 1 2005: 205–229. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Unusual Cases in Multiple Myeloma and a Dramatic Response in Metastatic Lung Cancer: CASE 1. Multiple Myeloma Relapse Presenting As Malignant Pericardial Effusion

Robert Zeiser, Björn Hackanson, Thorsten A. Bley, Jürgen Finke, and Hartmut Bertz

JCO Jan 1 2005: 230–231. [Full Text] [PDF]

Unusual Cases in Multiple Myeloma and a Dramatic Response in Metastatic Lung Cancer: CASE 2. Plasma Cell Myeloma Coexisting With Metastatic Breast Carcinoma in the Bone Marrow

Giancarlo Pruneri, Saverio Cinieri, Fedro Peccatori, and Giuseppe Viale

JCO Jan 1 2005: 232–233. [Full Text] [PDF]

Unusual Cases in Multiple Myeloma and a Dramatic Response in Metastatic Lung Cancer: CASE 3. Intracranial Plasmacytoma With Cranial Nerve Neuropathy in Multiple Myeloma

Carlos Montalban, José Martín-Aresti, José Luis Patier, Juan Martinez-San Millan, and Mónica García Cosio

JCO Jan 1 2005: 233–235. [Full Text] [PDF]

Unusual Cases in Multiple Myeloma and a Dramatic Response in Metastatic Lung Cancer: CASE 4. Mutation of the Epidermal Growth Factor Receptor in an Elderly Man With Advanced, Gefitinib-Responsive, Non–Small-Cell Lung Cancer

Daniel Cho, Olivier Kocher, Daniel G. Tenen, Balazs Halmos, Jeffrey C. Lee, Matthew L. Meyerson, and Pasi A. Janne

JCO Jan 1 2005: 235–237. [Full Text] [PDF]

ART OF ONCOLOGY

The Sounds of Silence: Sexuality Information for Cancer Patients

Anne Katz

JCO Jan 1 2005: 238–241. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Graft-Versus–Ewing Sarcoma Effect and Long-Term Remission Induced by Haploidentical Stem-Cell Transplantation in a Patient With Relapse of Metastatic Disease

Ewa Koscielniak, Ute Gross-Wieltsch, Joern Treuner, Peter Winkler, Thomas Klingebiel, Peter Lang, Peter Bader, Dietrich Niethammer, and Rupert Handgretinger

JCO Jan 1 2005: 242–244. [Full Text] [PDF]

Validity of Short-Term Consequences of Cancer Prevention and Screening Activities?

John Broderson, Hanne Thorsen, and Jill Cockburn

JCO Jan 1 2005: 244. [Full Text] [PDF]

In Reply:

Jennifer Cullen

JCO Jan 1 2005: 244-a–245. [Full Text] [PDF]

Radiotherapy in Advanced-Stage Hodgkin's Lymphoma

John M.M. Raemaekers, Berthe M.P. Aleman, and Michel Henry-Amar

JCO Jan 1 2005: 245–246. [Full Text] [PDF]

In Reply:

Siddhartha Laskar, Tejpal Gupta, and Mary Ann Muckaden

JCO Jan 1 2005: 246–247. [Full Text] [PDF]

Persistent Panhypogammaglobulinemia After CHOP-Rituximab for HIV-Related Lymphoma

Steven A. Miles and Marie McGratten

JCO Jan 1 2005: 247–248. [Full Text] [PDF]

Erratum

Erratum

JCO Jan 1 2005: 248. [Full Text] [PDF]

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