EDITORIALS

Standards of Proof, Standards of Practice, and Proof of Standards: A Tale of Two Trials

George P. Browman

JCO Apr 20 2005: 2583–2585. First published on Feb 14 2005; 10.1200/JCO.2005.11.910. [Full Text] [PDF]

Rhabdomyosarcoma: Many Similarities, a Few Philosophical Differences

Sarah S. Donaldson and James R. Anderson

JCO Apr 20 2005: 2586–2587. First published on Feb 22 2005; 10.1200/JCO.2005.11.909. [Full Text] [PDF]

Late Referrals to Palliative Care

Betty R. Ferrell

JCO Apr 20 2005: 2588–2589. First published on Feb 22 2005; 10.1200/JCO.2005.11.908. [Full Text] [PDF]

High Prevalence of Complementary and Alternative Medicine Use Among Cancer Patients: Implications for Research and Clinical Care

Barrie R. Cassileth and Andrew J. Vickers

JCO Apr 20 2005: 2590–2592. First published on Feb 22 2005; 10.1200/JCO.2005.11.922. [Full Text] [PDF]

COMMENTS AND CONTROVERSIES

Gay Men and Prostate Cancer: Invisible Diversity

Thomas O. Blank

JCO Apr 20 2005: 2593–2596. [Full Text] [PDF]

ORIGINAL REPORTS
Supportive Care and Quality of Life
	Weekly Epoetin Alfa Maintains Hemoglobin, Improves Quality of Life, and Reduces Transfusion in Breast Cancer Patients Receiving Chemotherapy
	Jose Chang, Felix Couture, Scott Young, Kara-Lee McWatters, and Catherine Y. Lau
	JCO Apr 20 2005: 2597–2605. First published on Sep 27 2004; 10.1200/JCO.2004.12.027. [Abstract] [Full Text] [PDF]
	Phase III, Randomized, Double-Blind Study of Epoetin Alfa Compared With Placebo in Anemic Patients Receiving Chemotherapy
	Thomas E. Witzig, Peter T. Silberstein, Charles L. Loprinzi, Jeff A. Sloan, Paul J. Novotny, James A. Mailliard, Kendrith M. Rowland, Steven R. Alberts, James E. Krook, Ralph Levitt, and Roscoe F. Morton
	JCO Apr 20 2005: 2606–2617. First published on Sep 27 2004; 10.1200/JCO.2004.10.020. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Treatment of Nonmetastatic Rhabdomyosarcoma in Childhood and Adolescence: Third Study of the International Society of Paediatric Oncology—SIOP Malignant Mesenchymal Tumor 89
	Michael C.G. Stevens, Annie Rey, Nathalie Bouvet, Caroline Ellershaw, Françoise Flamant, Jean Louis Habrand, H. Basil Marsden, Helene Martelli, Jose Sanchez de Toledo, Richard D Spicer, David Spooner, Marie Jose Terrier-Lacombe, Adrian van Unnik, and Odile Oberlin
	JCO Apr 20 2005: 2618–2628. First published on Feb 22 2005; 10.1200/JCO.2005.08.130. [Abstract] [Full Text] [PDF]
	Chronic Progressive Cardiac Dysfunction Years After Doxorubicin Therapy for Childhood Acute Lymphoblastic Leukemia
	Steven E. Lipshultz, Stuart R. Lipsitz, Stephen E. Sallan, Virginia M. Dalton, Suzanne M. Mone, Richard D. Gelber, and Steven D. Colan
	JCO Apr 20 2005: 2629–2636. [Abstract] [Full Text] [PDF]

Palliative Care
	Late Referrals to Specialized Palliative Care Service in Japan
	Tatsuya Morita, Tatsuo Akechi, Masayuki Ikenaga, Yoshiyuki Kizawa, Hiroyuki Kohara, Taketo Mukaiyama, Toshimichi Nakaho, Nobuaki Nakashima, Yasuo Shima, Tatsuhiro Matsubara, and Yosuke Uchitomi
	JCO Apr 20 2005: 2637–2644. First published on Feb 22 2005; 10.1200/JCO.2005.12.107. [Abstract] [Full Text] [PDF]

Complementary Therapy
	Nationwide Survey on Complementary and Alternative Medicine in Cancer Patients in Japan
	Ichinosuke Hyodo, Noriko Amano, Kenji Eguchi, Masaru Narabayashi, Jiro Imanishi, Midori Hirai, Tomohito Nakano, and Shigemitsu Takashima
	JCO Apr 20 2005: 2645–2654. First published on Feb 22 2005; 10.1200/JCO.2005.04.126. [Abstract] [Full Text] [PDF]

Treatment-Related Complications
	Infectious Complications of Central Venous Catheters Increase the Risk of Catheter-Related Thrombosis in Hematology Patients: A Prospective Study
	Cornelis J. van Rooden, Emile F. Schippers, Renée M.Y. Barge, Frits R. Rosendaal, Henri F.L. Guiot, Felix J.M. van der Meer, A. Edo Meinders, and Menno V. Huisman
	JCO Apr 20 2005: 2655–2660. [Abstract] [Full Text] [PDF]
	Pentostatin in Steroid-Refractory Acute Graft-Versus-Host Disease
	Javier Bolaños-Meade, David A. Jacobsohn, Jeffrey Margolis, Adam Ogden, M. Guillaume Wientjes, John C. Byrd, David M. Lucas, Viki Anders, Michele Phelps, Michael R. Grever, and Georgia B. Vogelsang
	JCO Apr 20 2005: 2661–2668. [Abstract] [Full Text] [PDF]

Melanoma
	Risk Factors and Individual Probabilities of Melanoma for Whites
	Eunyoung Cho, Bernard A. Rosner, Diane Feskanich, and Graham A. Colditz
	JCO Apr 20 2005: 2669–2675. [Abstract] [Full Text] [PDF]

Breast Cancer
	Doxorubicin With Cyclophosphamide Followed by Docetaxel Every 21 Days Compared With Doxorubicin and Docetaxel Every 14 Days As Preoperative Treatment in Operable Breast Cancer: The GEPARDUO Study of the German Breast Group
	Gunter von Minckwitz, Günter Raab, Angelika Caputo, Martin Schütte, Jörn Hilfrich, Jens U. Blohmer, Bernd Gerber, Serban D. Costa, Elisabeth Merkle, Holger Eidtmann, Dieter Lampe, Christian Jackisch, Andreas du Bois, and Manfred Kaufmann
	JCO Apr 20 2005: 2676–2685. [Abstract] [Full Text] [PDF]
	Epirubicin Increases Long-Term Survival in Adjuvant Chemotherapy of Patients With Poor-Prognosis, Node-Positive, Early Breast Cancer: 10-Year Follow-Up Results of the French Adjuvant Study Group 05 Randomized Trial
	Jacques Bonneterre, Henri Roché, Pierre Kerbrat, Alain Brémond, Pierre Fumoleau, Moïse Namer, Marie-Josèphe Goudier, Simon Schraub, Pierre Fargeot, and Isabelle Chapelle-Marcillac
	JCO Apr 20 2005: 2686–2693. [Abstract] [Full Text] [PDF]
	Sentinel Node Biopsy After Neoadjuvant Chemotherapy in Breast Cancer: Results From National Surgical Adjuvant Breast and Bowel Project Protocol B-27
	Eleftherios P. Mamounas, Ann Brown, Stewart Anderson, Roy Smith, Thomas Julian, Barbara Miller, Harry D. Bear, Christopher B. Caldwell, Alonzo P. Walker, Wendy M. Mikkelson, Jay S. Stauffer, Andre Robidoux, Heather Theoret, Atilla Sovan, Bernard Fisher, D. Lawrence Wickerham, and Norman Wolmark
	JCO Apr 20 2005: 2694–2702. [Abstract] [Full Text] [PDF]
	Electrical Impedance Scanning for the Early Detection of Breast Cancer in Young Women: Preliminary Results of a Multicenter Prospective Clinical Trial
	Alexander Stojadinovic, Aviram Nissan, Zahava Gallimidi, Sarah Lenington, Wende Logan, Margarita Zuley, Arieh Yeshaya, Mordechai Shimonov, Moshe Melloul, Scott Fields, Tanir Allweis, Ron Ginor, David Gur, and Craig D. Shriver
	JCO Apr 20 2005: 2703–2715. [Abstract] [Full Text] [PDF]
	Population-Based Validation of the Prognostic Model ADJUVANT! for Early Breast Cancer
	Ivo A. Olivotto, Chris D. Bajdik, Peter M. Ravdin, Caroline H. Speers, Andrew J. Coldman, Brian D. Norris, Greg J. Davis, Stephen K. Chia, and Karen A. Gelmon
	JCO Apr 20 2005: 2716–2725. [Abstract] [Full Text] [PDF]
	Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Metastatic and Locally Advanced Breast Cancer
	Jennifer A. Low, Suparna B. Wedam, James J. Lee, Arlene W. Berman, Adam Brufsky, Sherry X. Yang, Marianne S. Poruchynsky, Seth M. Steinberg, Nitin Mannan, Tito Fojo, and Sandra M. Swain
	JCO Apr 20 2005: 2726–2734. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Familial Gastrointestinal Stromal Tumor Syndrome: Phenotypic and Molecular Features in a Kindred
	Frederick P. Li, Jonathan A. Fletcher, Michael C. Heinrich, Judy E. Garber, Stephen E. Sallan, Clara Curiel-Lewandrowski, Anette Duensing, Matt van de Rijn, Lowell E. Schnipper, and George D. Demetri
	JCO Apr 20 2005: 2735–2743. [Abstract] [Full Text] [PDF]
	Chemokine Receptor CXCR4 Expression in Colorectal Cancer Patients Increases the Risk for Recurrence and for Poor Survival
	Joseph Kim, Hiroya Takeuchi, Stella T. Lam, Roderick R. Turner, He-Jing Wang, Christine Kuo, Leland Foshag, Anton J. Bilchik, and Dave S.B. Hoon
	JCO Apr 20 2005: 2744–2753. [Abstract] [Full Text] [PDF]
	Radiolabeled Somatostatin Analog [177Lu-DOTA0,Tyr3]Octreotate in Patients With Endocrine Gastroenteropancreatic Tumors
	Dik J. Kwekkeboom, Jaap J. Teunissen, Willem H. Bakker, Peter P. Kooij, Wouter W. de Herder, Richard A. Feelders, Casper H. van Eijck, Jan-Paul Esser, Boen L. Kam, and Eric P. Krenning
	JCO Apr 20 2005: 2754–2762. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Prognostic Value of Histologic Subtypes in Renal Cell Carcinoma: A Multicenter Experience
	Jean-Jacques Patard, Emmanuelle Leray, Nathalie Rioux-Leclercq, Luca Cindolo, Vincenzo Ficarra, Amnon Zisman, Alexandre De La Taille, Jacques Tostain, Walter Artibani, Claude C. Abbou, Bernard Lobel, François Guillé, Dominique K. Chopin, Peter F.A. Mulders, Christopher G. Wood, David A. Swanson, Robert A. Figlin, Arie S. Belldegrun, and Allan J. Pantuck
	JCO Apr 20 2005: 2763–2771. [Abstract] [Full Text] [PDF]
	Long-Term Outcomes Among Localized Prostate Cancer Survivors: Health-Related Quality-of-Life Changes After Radical Prostatectomy, External Radiation, and Brachytherapy
	David C. Miller, Martin G. Sanda, Rodney L. Dunn, James E. Montie, Hector Pimentel, Howard M. Sandler, William P. McLaughlin, and John T. Wei
	JCO Apr 20 2005: 2772–2780. [Abstract] [Full Text] [PDF]
	Retroperitoneal Lymph Node Dissection for Nonseminomatous Germ Cell Testicular Cancer: Impact of Patient Selection Factors on Outcome
	Andrew J. Stephenson, George J. Bosl, Robert J. Motzer, Michael W. Kattan, Jason Stasi, Dean F. Bajorin, and Joel Sheinfeld
	JCO Apr 20 2005: 2781–2788. [Abstract] [Full Text] [PDF]
	Docetaxel Followed by Hormone Therapy in Men Experiencing Increasing Prostate-Specific Antigen After Primary Local Treatments for Prostate Cancer
	Arif Hussain, Nancy Dawson, Pradip Amin, Christine Engstrom, Brenda Dorsey, Eliot Siegel, and Chuanfa Guo
	JCO Apr 20 2005: 2789–2796. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Diffuse Large B-Cell Lymphoma: Clinical and Biological Characterization and Outcome According to the Nodal or Extranodal Primary Origin
	Armando López-Guillermo, Luis Colomo, Mónica Jiménez, Francesc Bosch, Neus Villamor, Leonor Arenillas, Ana Muntañola, Silvia Montoto, Eva Giné, Dolors Colomer, Silvia Beà, Elías Campo, and Emili Montserrat
	JCO Apr 20 2005: 2797–2804. First published on Feb 22 2005; 10.1200/JCO.2005.07.155. [Abstract] [Full Text] [PDF]
	Phase I Study of BMS-214662, a Farnesyl Transferase Inhibitor in Patients With Acute Leukemias and High-Risk Myelodysplastic Syndromes
	Jorge Cortes, Stefan Faderl, Elihu Estey, Razelle Kurzrock, Deborah Thomas, Miloslav Beran, Guillermo Garcia-Manero, Alessandra Ferrajoli, Francis Giles, Charles Koller, Susan O'Brien, John Wright, Stephen A. Bai, and Hagop Kantarjian
	JCO Apr 20 2005: 2805–2812. First published on Feb 22 2005; 10.1200/JCO.2005.09.005. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Diagnostic Performance of Nanoparticle-Enhanced Magnetic Resonance Imaging in the Diagnosis of Lymph Node Metastases in Patients With Endometrial and Cervical Cancer
	Andrea G. Rockall, Syed A. Sohaib, Mukesh G. Harisinghani, Syed A. Babar, Naveena Singh, Arjun R. Jeyarajah, David H. Oram, Ian J. Jacobs, John H. Shepherd, and Rodney H. Reznek
	JCO Apr 20 2005: 2813–2821. [Abstract] [Full Text] [PDF]

Prevention
	Efficacy and Tolerability of Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer After Moderately Emetogenic Chemotherapy
	David G. Warr, Paul J. Hesketh, Richard J. Gralla, Hyman B. Muss, Jørn Herrstedt, Peter D. Eisenberg, Harry Raftopoulos, Steven M. Grunberg, Munir Gabriel, Anthony Rodgers, Norman Bohidar, George Klinger, Carolyn M. Hustad, Kevin J. Horgan, and Franck Skobieranda
	JCO Apr 20 2005: 2822–2830. [Abstract] [Full Text] [PDF]

Lung Cancer
	Randomized Phase III Study of Matrix Metalloproteinase Inhibitor BMS-275291 in Combination With Paclitaxel and Carboplatin in Advanced Non-Small-Cell Lung Cancer: National Cancer Institute of Canada-Clinical Trials Group Study BR.18
	Natasha B. Leighl, Luis Paz-Ares, Jean-Yves Douillard, Christian Peschel, Andrew Arnold, Alain Depierre, Armando Santoro, Daniel C. Betticher, Ulrich Gatzemeier, Jacek Jassem, Jeffrey Crawford, Dongsheng Tu, Andrea Bezjak, Jeffrey S. Humphrey, Maurizio Voi, Susan Galbraith, Katherine Hann, Lesley Seymour, and Frances A. Shepherd
	JCO Apr 20 2005: 2831–2839. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	COX-2: A Molecular Target for Colorectal Cancer Prevention
	Joanne R. Brown and Raymond N. DuBois
	JCO Apr 20 2005: 2840–2855. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Unusual Thoracic Problems in Patients With Malignancies: CASE 1. Neuroblastoma Presenting With Intracardiac Tumor Thrombus

Suneel N. Nagda, Simon S. Lo, Edward Melian, Ricarchito Manera, and Bahman Emami

JCO Apr 20 2005: 2856–2857. [Full Text] [PDF]

Unusual Thoracic Problems in Patients With Malignancies: CASE 2. Malignant Mesothelioma in a Patient With Long-Standing Pulmonary Alveolar Proteinosis

Rattiya Cheewakriangkrai, Alan Litwin, Maria E. Nava, and Nithya Ramnath

JCO Apr 20 2005: 2858–2859. [Full Text] [PDF]

Unusual Thoracic Problems in Patients With Malignancies: CASE 3. Carcinoid Tumor of the Thymus

Eric K. Hansen, Richard M. Krieg, Robert J. Azar, David M. Jablons, and Thierry M. Jahan

JCO Apr 20 2005: 2859–2861. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

The Ethics of Early Stopping Rules

Joseph Pater, Paul Goss, Jame Ingle, Wendy Shelley, and Lois Shepherd

JCO Apr 20 2005: 2862–2863. [Full Text] [PDF]

In Reply:

Stephen A. Cannistra

JCO Apr 20 2005: 2863–2864. [Full Text] [PDF]

Comments on Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Mist of Mysterious Results

Skye H. Cheng and Andrew T. Huang

JCO Apr 20 2005: 2864–2865. [Full Text] [PDF]

In Reply:

Dora Kwong and Jonathan Sham

JCO Apr 20 2005: 2865–2866. [Full Text] [PDF]

Continuation of Trastuzumab Beyond Disease Progression

Filippo Montemurro, Roberto Faggiuolo, Stefania Redana, Michela Donadio, Monica Minischetti, Antonio Durando, Guido Vietti-Ramus, Roberta Buosi, and Massimo Aglietta

JCO Apr 20 2005: 2866–2868. [Full Text] [PDF]

In Reply:

Gabriel N. Hortobagyi

JCO Apr 20 2005: 2868–2869. [Full Text] [PDF]

What Is the Appropriate Radiotherapy Protocol for Older Patients With Newly Diagnosed Glioblastoma?

Johannes Lutterbach and Christoph Ostertag

JCO Apr 20 2005: 2869–2870. [Full Text] [PDF]

Time for Reappraisal of Progesterone-Receptor Testing in Breast Cancer Management

Gaëtan MacGrogan, Isabelle de Mascarel, Ghyslaine Sierankowski, Louis Mauriac, Marc Debled, Michel Durand, Christine Tunon De Lara, Antoine Avril, Véronique Picot, and Simone Mathoulin-Pélissier

JCO Apr 20 2005: 2870–2871. [Full Text] [PDF]

In Reply:

Mousumi Banerjee and William Hryniuk

JCO Apr 20 2005: 2871. [Full Text] [PDF]

Optimizing End Points and Outcomes in Cancer-Associated Wasting

M. Dahele and L. Wall

JCO Apr 20 2005: 2871-a–2872. [Full Text] [PDF]

In Reply:

Aminah Jatoi, Charles Loprinzi, Kendrith Rowland, and Shaker Dakhil

JCO Apr 20 2005: 2872–2873. [Full Text] [PDF]

Cardiotoxicity of Epirubicin Versus Doxorubicin: Cost and Clinical Results

Gerard J. Ventura

JCO Apr 20 2005: 2873. [Full Text] [PDF]

In Reply:

Jacques Bonneterre

JCO Apr 20 2005: 2873-a–2874. [Full Text] [PDF]

Do PET and SNB Reduce the Rate of Elective Neck Dissection? A Hypothesis Still in Need of Validation

Benjamin D. Smith, Brian E. Lally, Bruce G. Haffty, and Lynn D. Wilson

JCO Apr 20 2005: 2874–2875. [Full Text] [PDF]

In Reply:

Adorján F. Kovács

JCO Apr 20 2005: 2875–2876. [Full Text] [PDF]

Errata

ERRATUM

JCO Apr 20 2005: 2877. [Full Text] [PDF]

ERRATUM

JCO Apr 20 2005: 2877-a. [Full Text] [PDF]

ERRATUM

JCO Apr 20 2005: 2877-b. [Full Text] [PDF]

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