EDITORIALS

Trastuzumab Plus Chemotherapy: Convincing Survival Benefit or Not?

Charles L. Vogel and Elizabeth Tan-Chiu

JCO Jul 1 2005: 4247–4250. First published on May 23 2005; 10.1200/JCO.2005.12.903. [Full Text] [PDF]

Contralateral Prophylactic Mastectomy: Quantifying Benefits and Weighing the Harms

Kathy J. Helzlsouer

JCO Jul 1 2005: 4251–4253. First published on Mar 28 2005; 10.1200/JCO.2005.12.904. [Full Text] [PDF]

A Comment on the Utility of Recursive Partitioning

Brent A. Blumenstein

JCO Jul 1 2005: 4254–4255. First published on Mar 21 2005; 10.1200/JCO.2005.12.908. [Full Text] [PDF]

Carcinoma of the Esophagus: Is Biology Screaming in My Deaf Ears?

Jaffer A. Ajani

JCO Jul 1 2005: 4256–4258. First published on Mar 21 2005; 10.1200/JCO.2005.12.911. [Full Text] [PDF]

Fertility After Breast Cancer: Questions Abound

Ann H. Partridge and Eric P. Winer

JCO Jul 1 2005: 4259–4261. First published on Apr 11 2005; 10.1200/JCO.2005.12.914. [Full Text] [PDF]

High-Dose Therapy and Stem-Cell Rescue for Ewing's Family of Tumors in Second Remission

Neyssa Marina and Paul A. Meyers

JCO Jul 1 2005: 4262–4264. First published on Mar 21 2005; 10.1200/JCO.2005.12.915. [Full Text] [PDF]

ORIGINAL REPORTS
Breast Cancer
	Randomized Phase II Trial of the Efficacy and Safety of Trastuzumab Combined With Docetaxel in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer Administered As First-Line Treatment: The M77001 Study Group
	Michel Marty, Francesco Cognetti, Dominique Maraninchi, Ray Snyder, Louis Mauriac, Michèle Tubiana-Hulin, Stephen Chan, David Grimes, Antonio Antón, Ana Lluch, John Kennedy, Kenneth O’Byrne, PierFranco Conte, Michael Green, Carol Ward, Karen Mayne, and Jean-Marc Extra
	JCO Jul 1 2005: 4265–4274. First published on May 23 2005; 10.1200/JCO.2005.04.173. [Abstract] [Full Text] [PDF]
	Efficacy of Prophylactic Mastectomy in Women With Unilateral Breast Cancer: A Cancer Research Network Project
	Lisa J. Herrinton, William E. Barlow, Onchee Yu, Ann M. Geiger, Joann G. Elmore, Mary B. Barton, Emily L. Harris, Sharon Rolnick, Roy Pardee, Gail Husson, Ana Macedo, and Suzanne W. Fletcher
	JCO Jul 1 2005: 4275–4286. First published on Mar 28 2005; 10.1200/JCO.2005.10.080. [Abstract] [Full Text] [PDF]
	Comparison of HER2 Status by Fluorescence in Situ Hybridization and Immunohistochemistry to Predict Benefit From Dose Escalation of Adjuvant Doxorubicin-Based Therapy in Node-Positive Breast Cancer Patients
	Lynn G. Dressler, Donald A. Berry, Gloria Broadwater, David Cowan, Kelly Cox, Stephanie Griffin, Ashley Miller, Jessica Tse, Debra Novotny, Diane L. Persons, Maurice Barcos, I. Craig Henderson, Edison T. Liu, Ann Thor, Dan Budman, Hy Muss, Larry Norton, and Daniel F. Hayes
	JCO Jul 1 2005: 4287–4297. [Abstract] [Full Text] [PDF]
	Interventions to Enhance Physical and Psychological Functioning Among Younger Women Who Are Ending Nonhormonal Adjuvant Treatment for Early-Stage Breast Cancer
	Michael F. Scheier, Vicki S. Helgeson, Richard Schulz, Suzanne Colvin, Sarah Berga, Michael W. Bridges, Judy Knapp, Kristina Gerszten, and William Scott Pappert
	JCO Jul 1 2005: 4298–4311. [Abstract] [Full Text] [PDF]
	Morbidity After Sentinel Lymph Node Biopsy in Primary Breast Cancer: Results From a Randomized Controlled Trial
	Anand David Purushotham, Sara Upponi, Manfred Borislav Klevesath, Lynda Bobrow, Keith Millar, Jonathan Peter Myles, and Stephen William Duffy
	JCO Jul 1 2005: 4312–4321. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Improved Detection of Prostate Cancer Using Classification and Regression Tree Analysis
	Mark Garzotto, Tomasz M. Beer, R. Guy Hudson, Laura Peters, Yi-Ching Hsieh, Eduardo Barrera, Thomas Klein, and Motomi Mori
	JCO Jul 1 2005: 4322–4329. First published on Mar 21 2005; 10.1200/JCO.2005.11.136. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Complete Response to Neoadjuvant Chemoradiotherapy in Esophageal Carcinoma Is Associated With Significantly Improved Survival
	Adam C. Berger, Jeffrey Farma, Walter J. Scott, Gary Freedman, Louis Weiner, Jonathan D. Cheng, Hao Wang, and Melvyn Goldberg
	JCO Jul 1 2005: 4330–4337. First published on Mar 21 2005; 10.1200/JCO.2005.05.017. [Abstract] [Full Text] [PDF]
	Randomized Controlled Trial of Tamoxifen in Advanced Hepatocellular Carcinoma
	Jean-Claude Barbare, Olivier Bouché, Franck Bonnetain, Jean-Luc Raoul, Philippe Rougier, Armand Abergel, Valérie Boige, Bernard Denis, Alain Blanchi, Alexandre Pariente, Chantal Milan, and Laurent Bedenne
	JCO Jul 1 2005: 4338–4346. [Abstract] [Full Text] [PDF]

Treatment-Related Complications
	Fertility Preservation in Breast Cancer Patients: A Prospective Controlled Comparison of Ovarian Stimulation With Tamoxifen and Letrozole for Embryo Cryopreservation
	Kutluk Oktay, Erkan Buyuk, Natalie Libertella, Munire Akar, and Zev Rosenwaks
	JCO Jul 1 2005: 4347–4353. First published on Apr 11 2005; 10.1200/JCO.2005.05.037. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Survival After Recurrence of Ewing’s Sarcoma Family of Tumors
	Lisa M. Barker, Thomas W. Pendergrass, Jean E. Sanders, and Douglas S. Hawkins
	JCO Jul 1 2005: 4354–4362. First published on Mar 21 2005; 10.1200/JCO.2005.05.105. [Abstract] [Full Text] [PDF]
	Soft Tissue Sarcoma or Malignant Mesenchymal Tumors in the First Year of Life: Experience of the International Society of Pediatric Oncology (SIOP) Malignant Mesenchymal Tumor Committee
	D. Orbach, A. Rey, O. Oberlin, J. Sanchez de Toledo, M.J. Terrier-Lacombe, A. van Unnik, E. Quintana, and M.C.G. Stevens
	JCO Jul 1 2005: 4363–4371. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Prognostic Factors and Outcome of Human Herpesvirus 8–Associated Primary Effusion Lymphoma in Patients With AIDS
	Emmanuelle Boulanger, Laurence Gérard, Jean Gabarre, Jean-Michel Molina, Christophe Rapp, Jean-François Abino, Jacques Cadranel, Sylvie Chevret, and Eric Oksenhendler
	JCO Jul 1 2005: 4372–4380. [Abstract] [Full Text] [PDF]
	Extent of Damage and Repair in the p53 Tumor-Suppressor Gene After Treatment of Myeloma Patients With High-Dose Melphalan and Autologous Blood Stem-Cell Transplantation Is Individualized and May Predict Clinical Outcome
	Meletios A. Dimopoulos, Vassilis L. Souliotis, Athanasios Anagnostopoulos, Christos Papadimitriou, and Petros P. Sfikakis
	JCO Jul 1 2005: 4381–4389. First published on May 9 2005; 10.1200/JCO.2005.07.385. [Abstract] [Full Text] [PDF]
	Phase I/II Study of Galiximab, an Anti-CD80 Antibody, for Relapsed or Refractory Follicular Lymphoma
	Myron S. Czuczman, Aron Thall, Thomas E. Witzig, Julie M. Vose, Anas Younes, Christos Emmanouilides, Thomas P. Miller, Joseph O. Moore, John P. Leonard, Leo I. Gordon, John Sweetenham, Baha Alkuzweny, Deborah M. Finucane, and Bryan R. Leigh
	JCO Jul 1 2005: 4390–4398. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Quality of Life of Long-Term Survivors of Breast Cancer and Lymphoma Treated With Standard-Dose Chemotherapy or Local Therapy
	Tim A. Ahles, Andrew J. Saykin, Charlotte T. Furstenberg, Bernard Cole, Leila A. Mott, Linda Titus-Ernstoff, Karen Skalla, Marie Bakitas, and Peter M. Silberfarb
	JCO Jul 1 2005: 4399–4405. [Abstract] [Full Text] [PDF]
	Outcome of Cancer Patients Considered for Intensive Care Unit Admission: A Hospital-Wide Prospective Study
	Guillaume Thiéry, Élie Azoulay, Michael Darmon, Magali Ciroldi, Sandra De Miranda, Vincent Lévy, Fabienne Fieux, Delphine Moreau, Jean Roger Le Gall, and Benoît Schlemmer
	JCO Jul 1 2005: 4406–4413. [Abstract] [Full Text] [PDF]

Clinical Practice
	Persistence of Medical Change at Implementation of Clinical Guidelines on Medical Practice: A Controlled Study in a Cancer Network
	Isabelle Ray-Coquard, Thierry Philip, Guy de Laroche, Xavier Froger, Jean-Philippe Suchaud, Alain Voloch, Hélène Mathieu-Daudé, Antoine Lurkin, Fadila Farsi, Pierre Bertrand, and Franck Chauvin
	JCO Jul 1 2005: 4414–4423. [Abstract] [Full Text] [PDF]

Cancer Related Complications
	Multicenter Study of a Frozen Glove to Prevent Docetaxel-Induced Onycholysis and Cutaneous Toxicity of the Hand
	Florian Scotté, Jean-Marc Tourani, Eugeniu Banu, Michel Peyromaure, Eric Levy, Sandrine Marsan, Emmanuelle Magherini, Elisabeth Fabre-Guillevin, Jean-Marie Andrieu, and Stéphane Oudard
	JCO Jul 1 2005: 4424–4429. [Abstract] [Full Text] [PDF]

AIDS-Related Cancer
	AIDS-Related Burkitt's Lymphoma Versus Diffuse Large-Cell Lymphoma in the Pre–Highly Active Antiretroviral Therapy (HAART) and HAART Eras: Significant Differences in Survival With Standard Chemotherapy
	Soon Thye Lim, Roksana Karim, Bharat N. Nathwani, Anil Tulpule, Byron Espina, and Alexandra M. Levine
	JCO Jul 1 2005: 4430–4438. First published on May 9 2005; 10.1200/JCO.2005.11.973. [Abstract] [Full Text] [PDF]

Prevention
	Effects of 9-cis-Retinoic Acid on the Insulin-Like Growth Factor Axis in Former Smokers
	Ho-Young Lee, Yoon Soo Chang, Ji-Youn Han, Diane D. Liu, J. Jack Lee, Reuben Lotan, Margaret R. Spitz, and Waun Ki Hong
	JCO Jul 1 2005: 4439–4449. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Randomized Phase II Designs in Cancer Clinical Trials: Current Status and Future Directions
	J. Jack Lee and Lei Feng
	JCO Jul 1 2005: 4450–4457. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Patients With Unusual Bladder Malignancies and a Rare Cause of Splenomegaly: CASE 1. Small-Cell Carcinoma of the Urinary Bladder

Mohammadbagher Ziari, Guru Sonpavde, Steven Shen, Bin S. Teh, Tung Shu, and Seth P. Lerner

JCO Jul 1 2005: 4458–4459. [Full Text] [PDF]

Patients With Unusual Bladder Malignancies and a Rare Cause of Splenomegaly: CASE 2. Rhabdomyosarcoma of the Urinary Bladder in an Adult

Mohammadbagher Ziari, Guru Sonpavde, Steven Shen, Jim Zhai, Bin S. Teh, and Seth P. Lerner

JCO Jul 1 2005: 4459–4460. [Full Text] [PDF]

Patients With Unusual Bladder Malignancies and a Rare Cause of Splenomegaly: CASE 3. Littoral Cell Angioma of the Spleen in a Patient With Previous Lymphoma

Justin D. Floyd, Paul A. Kaplan, Edward R. Sauter, Michael C. Perry, and Donald C. Doll

JCO Jul 1 2005: 4460–4462. [Full Text] [PDF]

ART OF ONCOLOGY

Talking to a Patient

Frank L. Meyskens, Jr, Päivi Hietanen, and Ian F. Tannock

JCO Jul 1 2005: 4463–4464. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Hyperbaric Oxygen Therapy for Radionecrosis: Clear Advice From Confusing Data

Gerard Laden

JCO Jul 1 2005: 4465. [Full Text] [PDF]

Comment on "Hyperbaric Oxygen Therapy for Radionecrosis of the Jaw: A Randomized, Placebo-Controlled, Double-Blind Trial From the ORN96 Study Group"

Richard van Merkesteyn and Dirk Jan Bakker

JCO Jul 1 2005: 4465-a–4466. [Full Text] [PDF]

In Reply:

Djillali Annane and Sylvie Chevret

JCO Jul 1 2005: 4466–4468. [Full Text] [PDF]

Withholding Information From Study Participants in Clinical Trials: Ethical Considerations

Michael Dosik

JCO Jul 1 2005: 4468–4469. [Full Text] [PDF]

In Reply:

Spyros Retsas

JCO Jul 1 2005: 4469. [Full Text] [PDF]

Challenge in the Treatment of Estrogen-Receptor–Negative Ductal Carcinoma in Situ

Kadri Altundag

JCO Jul 1 2005: 4469-a–4470. [Full Text] [PDF]

Regression of Low-Grade Non-Hodgkin's Lymphoma After Treatment With Pegylated Interferon Plus Ribavirin in Hepatitis C Virus Infection

Cesare Mazzaro, Michele Spina, and Umberto Tirelli

JCO Jul 1 2005: 4470–4471. [Full Text] [PDF]

In Reply:

Daniele Vallisa, Patrizia Bernuzzi, Antonio Lazzaro, Elena Trabacchi, Elisa Anselmi, Anna Lisa Arcari, Carlo Moroni, Raffaella Bertè, and Luigi Cavanna

JCO Jul 1 2005: 4471. [Full Text] [PDF]

Internet-Based Approach to Multi-Institutional Patient Recruitment in the Medico-Legal Age

Ricardo J. Komotar, Brad E. Zacharia, J. Mocco, Evan R. Ransom, Jeffrey P. Davis, George Gasparis, and Jeffrey N. Bruce

JCO Jul 1 2005: 4471-a–4473. [Full Text] [PDF]

Successful Use of Haploidentical Stem-Cell Transplantation With KIR Mismatch As Initial Therapy for Poor-Risk Myelodysplastic Syndrome

Mark A. Dawson and Andrew Spencer

JCO Jul 1 2005: 4473–4474. [Full Text] [PDF]

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