EDITORIALS

Imaging and Other Biomarkers in Early Clinical Studies: One Step at a Time or Re-Engineering Drug Development?

Jerry M. Collins

JCO Aug 20 2005: 5417–5419. First published on Jul 18 2005; 10.1200/JCO.2005.05.907. [Full Text] [PDF]

Ecteinascidin-743 (ET-743): Early Test or Effective Treatment in Soft Tissue Sarcomas?

Jaap Verweij

JCO Aug 20 2005: 5420–5423. [Full Text] [PDF]

Quality-of-Life Assessment in Pediatric Brain Tumor Patients and Survivors: Lessons Learned and Challenges to Face

May Lin Tao and Susan K. Parsons

JCO Aug 20 2005: 5424–5426. [Full Text] [PDF]

Dignity Therapy: Advancing the Science of Spiritual Care in Terminal Illness

Betty Ferrell

JCO Aug 20 2005: 5427–5428. [Full Text] [PDF]

Variation in the Choice of Breast-Conserving Surgery or Mastectomy: Patient or Physician Decision Making?

Ann B. Nattinger

JCO Aug 20 2005: 5429–5431. [Full Text] [PDF]

What Is Atypical Lobular Hyperplasia and What Does It Mean for the Patient?

David L. Page and Jean F. Simpson

JCO Aug 20 2005: 5432–5433. [Full Text] [PDF]

Testing Chemotherapy for Breast Cancer: Timing Is Everything

Clifford Hudis

JCO Aug 20 2005: 5434–5436. [Full Text] [PDF]

Predicting the Future From Trials of the Past: Epidermal Growth Factor Receptor Expression and Outcome of Fractionated Radiation Therapy Trials

Adam P. Dicker and Ulrich Rodeck

JCO Aug 20 2005: 5437–5439. [Full Text] [PDF]

Cetuximab and Cisplatin for Chemotherapy-Refractory Squamous Cell Cancer of the Head and Neck

Barbara Burtness

JCO Aug 20 2005: 5440–5442. First published on Jul 11 2005; 10.1200/JCO.2005.02.002. [Full Text] [PDF]

Screening for Familial Ovarian Cancer: The Need for Well-Designed Prospective Studies

Ian Jacobs

JCO Aug 20 2005: 5443–5445. [Full Text] [PDF]

Gefitinib in Colorectal Cancer: If Wishes Were Horses

Charles D. Blanke

JCO Aug 20 2005: 5446–5449. [Full Text] [PDF]

Combined-Modality Neoadjuvant Therapy for Rectal Cancer

Michael J. O'Connell

JCO Aug 20 2005: 5450–5451. First published on Jul 11 2005; 10.1200/JCO.2005.04.904. [Full Text] [PDF]

Thymidylate Synthase in Nodal Metastases: Prognostic for Chemosensitivity But Not for Adjuvant Therapy?

James D. Ahlgren

JCO Aug 20 2005: 5452–5454. First published on Jul 11 2005; 10.1200/JCO.2005.04.907. [Full Text] [PDF]

Implications for Tumor Control During Protection of Normal Tissues With Antioxidants

Kevin Camphausen, Deborah Citrin, Murali C. Krishna, and James B. Mitchell

JCO Aug 20 2005: 5455–5457. First published on Jul 18 2005; 10.1200/JCO.2005.05.903. [Full Text] [PDF]

A Teachable Moment for Oncologists: Cancer Survivors, 10 Million Strong and Growing!

Patricia A. Ganz

JCO Aug 20 2005: 5458–5460. First published on Jul 25 2005; 10.1200/JCO.2005.04.916. [Full Text] [PDF]

Early Viewing of Noninferiority Trials in Progress

James J. Dignam

JCO Aug 20 2005: 5461–5463. First published on Jul 18 2005; 10.1200/JCO.2005.04.906. [Full Text] [PDF]

ORIGINAL REPORTS
Phase I and Clinical Pharmacology
	Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Pharmacodynamic Measure of Response After Acute Dosing of AG-013736, an Oral Angiogenesis Inhibitor, in Patients With Advanced Solid Tumors: Results From a Phase I Study
	Glenn Liu, Hope S. Rugo, George Wilding, Teresa M. McShane, Jeffrey L. Evelhoch, Chaan Ng, Edward Jackson, Frederick Kelcz, Benjamin M. Yeh, Fred T. Lee, Jr, Chusilp Charnsangavej, John W. Park, Edward A. Ashton, Heidi M. Steinfeldt, Yazdi K. Pithavala, Steven D. Reich, and Roy S. Herbst
	JCO Aug 20 2005: 5464–5473. First published on Jul 18 2005; 10.1200/JCO.2005.04.143. [Abstract] [Full Text] [PDF]
	Phase I Trial of the Oral Antiangiogenesis Agent AG-013736 in Patients With Advanced Solid Tumors: Pharmacokinetic and Clinical Results
	Hope S. Rugo, Roy S. Herbst, Glenn Liu, John W. Park, Merrill S. Kies, Heidi M. Steinfeldt, Yazdi K. Pithavala, Steven D. Reich, James L. Freddo, and George Wilding
	JCO Aug 20 2005: 5474–5483. First published on Jul 18 2005; 10.1200/JCO.2005.04.192. [Abstract] [Full Text] [PDF]
	Ecteinascidin-743 (ET-743) for Chemotherapy-Naive Patients With Advanced Soft Tissue Sarcomas: Multicenter Phase II and Pharmacokinetic Study
	R. Garcia-Carbonero, J.G. Supko, R.G. Maki, J. Manola, D.P. Ryan, D. Harmon, T.A. Puchalski, G. Goss, M.V. Seiden, A. Waxman, M.T. Quigley, T. Lopez, M.A. Sancho, J. Jimeno, C. Guzman, and G.D. Demetri
	JCO Aug 20 2005: 5484–5492. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Profile of Daily Life in Children With Brain Tumors: An Assessment of Health-Related Quality of Life
	Sundeep R. Bhat, Tress L. Goodwin, Tasha M. Burwinkle, Meagan F. Lansdale, Gary V. Dahl, Stephen L. Huhn, Iris C. Gibbs, Sarah S. Donaldson, Ruth K. Rosenblum, James W. Varni, and Paul G. Fisher
	JCO Aug 20 2005: 5493–5500. [Abstract] [Full Text] [PDF]
	Prevalence and Correlates of Fatigue in Long-Term Survivors of Childhood Leukemia
	Kathleen A. Meeske, Stuart E. Siegel, Denise R. Globe, Wendy J. Mack, and Leslie Bernstein
	JCO Aug 20 2005: 5501–5510. [Abstract] [Full Text] [PDF]
	Neurocognitive Consequences of Risk-Adapted Therapy for Childhood Medulloblastoma
	Raymond K. Mulhern, Shawna L. Palmer, Thomas E. Merchant, Dana Wallace, Mehmet Kocak, Pim Brouwers, Kevin Krull, Murali Chintagumpala, Robyn Stargatt, David M. Ashley, Vida L. Tyc, Larry Kun, James Boyett, and Amar Gajjar
	JCO Aug 20 2005: 5511–5519. [Abstract] [Full Text] [PDF]

Palliative Care
	Dignity Therapy: A Novel Psychotherapeutic Intervention for Patients Near the End of Life
	Harvey Max Chochinov, Thomas Hack, Thomas Hassard, Linda J. Kristjanson, Susan McClement, and Mike Harlos
	JCO Aug 20 2005: 5520–5525. [Abstract] [Full Text] [PDF]

Breast Cancer
	Patient Involvement in Surgery Treatment Decisions for Breast Cancer
	Steven J. Katz, Paula M. Lantz, Nancy K. Janz, Angela Fagerlin, Kendra Schwartz, Lihua Liu, Dennis Deapen, Barbara Salem, Indu Lakhani, and Monica Morrow
	JCO Aug 20 2005: 5526–5533. [Abstract] [Full Text] [PDF]
	Bilateral Risk for Subsequent Breast Cancer After Lobular Carcinoma-In-Situ: Analysis of Surveillance, Epidemiology, and End Results Data
	Paul J. Chuba, Merlin R. Hamre, Johnny Yap, Richard K. Severson, David Lucas, Falah Shamsa, and Amr Aref
	JCO Aug 20 2005: 5534–5541. [Abstract] [Full Text] [PDF]
	Randomized Phase III Study of Docetaxel Compared With Paclitaxel in Metastatic Breast Cancer
	S.E. Jones, J. Erban, B. Overmoyer, G.T. Budd, L. Hutchins, E. Lower, L. Laufman, S. Sundaram, W.J. Urba, K.I. Pritchard, R. Mennel, D. Richards, S. Olsen, M.L. Meyers, and P.M. Ravdin
	JCO Aug 20 2005: 5542–5551. [Abstract] [Full Text] [PDF]
	Drug-Metabolizing Enzyme Polymorphisms Predict Clinical Outcome in a Node-Positive Breast Cancer Cohort
	Angela DeMichele, Richard Aplenc, Jeffrey Botbyl, Theresa Colligan, Lisa Wray, Melissa Klein-Cabral, Andrea Foulkes, Phyllis Gimotty, John Glick, Barbara Weber, Edward Stadtmauer, and Timothy R. Rebbeck
	JCO Aug 20 2005: 5552–5559. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Epidermal Growth Factor Receptor Expression in Pretreatment Biopsies From Head and Neck Squamous Cell Carcinoma As a Predictive Factor for a Benefit From Accelerated Radiation Therapy in a Randomized Controlled Trial
	Søren M. Bentzen, Beste M. Atasoy, Frances M. Daley, Stanley Dische, Paul I. Richman, Michele I. Saunders, Klaus R. Trott, and George D. Wilson
	JCO Aug 20 2005: 5560–5567. [Abstract] [Full Text] [PDF]
	Phase II Multicenter Study of the Antiepidermal Growth Factor Receptor Monoclonal Antibody Cetuximab in Combination With Platinum-Based Chemotherapy in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck
	José Baselga, José M. Trigo, Jean Bourhis, Jacques Tortochaux, Hernán Cortés-Funes, Ricardo Hitt, Pere Gascón, Nadia Amellal, Andreas Harstrick, and André Eckardt
	JCO Aug 20 2005: 5568–5577. First published on Jul 11 2005; 10.1200/JCO.2005.07.119. [Abstract] [Full Text] [PDF]
	Phase II Multicenter Study of the Epidermal Growth Factor Receptor Antibody Cetuximab and Cisplatin for Recurrent and Refractory Squamous Cell Carcinoma of the Head and Neck
	Roy S. Herbst, Matthew Arquette, Dong M. Shin, Karel Dicke, Everett E. Vokes, Nozar Azarnia, Waun Ki Hong, and Merrill S. Kies
	JCO Aug 20 2005: 5578–5587. First published on Jul 11 2005; 10.1200/JCO.2005.07.120. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Screening for Familial Ovarian Cancer: Failure of Current Protocols to Detect Ovarian Cancer at an Early Stage According to the International Federation of Gynecology and Obstetrics System
	Diane Stirling, D. Gareth R. Evans, Gabriella Pichert, Andrew Shenton, Elaine N. Kirk, Sylvia Rimmer, C. Michael Steel, Sheila Lawson, R.M. Camille Busby-Earle, Jane Walker, Fiona I. Lalloo, Diana M. Eccles, Anneke M. Lucassen, and Mary E. Porteous
	JCO Aug 20 2005: 5588–5596. [Abstract] [Full Text] [PDF]
	Multicenter, Randomized Phase II Trial of Oral CI-1033 for Previously Treated Advanced Ovarian Cancer
	Susana Campos, Oday Hamid, Michael V. Seiden, Amit Oza, Marie Plante, Ronald K. Potkul, Peter F. Lenehan, Eric P. Kaldjian, Mary L. Varterasian, Cheryl Jordan, Claudie Charbonneau, and Hal Hirte
	JCO Aug 20 2005: 5597–5604. [Abstract] [Full Text] [PDF]
	Quality-of-Life Comparisons in a Randomized Trial of Interval Secondary Cytoreduction in Advanced Ovarian Carcinoma: A Gynecologic Oncology Group Study
	Lari Wenzel, Helen Q. Huang, Bradley J. Monk, Peter G. Rose, and David Cella
	JCO Aug 20 2005: 5605–5612. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Phase II Study of Gefitinib, Fluorouracil, Leucovorin, and Oxaliplatin Therapy in Previously Treated Patients With Metastatic Colorectal Cancer
	Timothy Kuo, Cheryl D. Cho, Joanne Halsey, Heather A. Wakelee, Ranjana H. Advani, James M. Ford, George A. Fisher, and Branimir I. Sikic
	JCO Aug 20 2005: 5613–5619. [Abstract] [Full Text] [PDF]
	Enhanced Tumorocidal Effect of Chemotherapy With Preoperative Radiotherapy for Rectal Cancer: Preliminary Results—EORTC 22921
	Jean-François Bosset, Gilles Calais, Laurent Mineur, Philippe Maingon, Ljiljana Radosevic-Jelic, Alain Daban, Etienne Bardet, Alexander Beny, Antoine Briffaux, and Laurence Collette
	JCO Aug 20 2005: 5620–5627. First published on Jul 11 2005; 10.1200/JCO.2005.02.113. [Abstract] [Full Text] [PDF]
	Detection of Thymidylate Synthase Expression in Lymph Node Metastases of Colorectal Cancer Can Improve the Prognostic Information
	Katarina Öhrling, David Edler, Marja Hallström, Peter Ragnhammar, and Henric Blomgren
	JCO Aug 20 2005: 5628–5634. First published on Jul 11 2005; 10.1200/JCO.2005.12.130. [Abstract] [Full Text] [PDF]
	Determination of TP53 Mutation Is More Relevant Than Microsatellite Instability Status for the Prediction of Disease-Free Survival in Adjuvant-Treated Stage III Colon Cancer Patients
	Jantine L. Westra, Michael Schaapveld, Harry Hollema, Jelle P. de Boer, Marian M.J. Kraak, Debora de Jong, Arja ter Elst, Nanno H. Mulder, Charles H.C.M. Buys, Robert M.W. Hofstra, and John T.M. Plukker
	JCO Aug 20 2005: 5635–5643. [Abstract] [Full Text] [PDF]
	Swedish Rectal Cancer Trial: Long Lasting Benefits From Radiotherapy on Survival and Local Recurrence Rate
	Joakim Folkesson, Helgi Birgisson, Lars Pahlman, Bjorn Cedermark, Bengt Glimelius, and Ulf Gunnarsson
	JCO Aug 20 2005: 5644–5650. [Abstract] [Full Text] [PDF]
	Adenomatous Polyposis Families That Screen APC Mutation–Negative by Conventional Methods Are Genetically Heterogeneous
	Elise T. Renkonen, Pekka Nieminen, Wael M. Abdel-Rahman, Anu-Liisa Moisio, Irma Järvelä, Sirpa Arte, Heikki J. Järvinen, and Päivi Peltomäki
	JCO Aug 20 2005: 5651–5659. [Abstract] [Full Text] [PDF]
	Phase II Multi-Institutional Randomized Trial of Docetaxel Plus Cisplatin With or Without Fluorouracil in Patients With Untreated, Advanced Gastric, or Gastroesophageal Adenocarcinoma
	Jaffer A. Ajani, Miguel B. Fodor, Sergei A. Tjulandin, Vladimir M. Moiseyenko, Yee Chao, Sebastiao Cabral Filho, Alejandro Majlis, Sylvie Assadourian, and Eric Van Cutsem
	JCO Aug 20 2005: 5660–5667. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Prognostic Value of Circulating Plasma Cells in Monoclonal Gammopathy of Undetermined Significance
	Shaji Kumar, S. Vincent Rajkumar, Robert A. Kyle, Martha Q. Lacy, Angela Dispenzieri, Rafael Fonseca, John A. Lust, Morie A. Gertz, Philip R. Greipp, and Thomas E. Witzig
	JCO Aug 20 2005: 5668–5674. [Abstract] [Full Text] [PDF]
	Sequential Regimen of Chemotherapy, Reduced-Intensity Conditioning for Allogeneic Stem-Cell Transplantation, and Prophylactic Donor Lymphocyte Transfusion in High-Risk Acute Myeloid Leukemia and Myelodysplastic Syndrome
	Christoph Schmid, Michael Schleuning, Georg Ledderose, Johanna Tischer, and Hans-Jochem Kolb
	JCO Aug 20 2005: 5675–5687. [Abstract] [Full Text] [PDF]
	Circulating CD34+, CD133+, and Vascular Endothelial Growth Factor Receptor 2–Positive Endothelial Progenitor Cells in Myelofibrosis With Myeloid Metaplasia
	Margherita Massa, Vittorio Rosti, Isabella Ramajoli, Rita Campanelli, Alessandro Pecci, Gianluca Viarengo, Valentina Meli, Monia Marchetti, Ronald Hoffman, and Giovanni Barosi
	JCO Aug 20 2005: 5688–5695. [Abstract] [Full Text] [PDF]
	Abbreviated Chemotherapy With Fludarabine Followed by Tositumomab and Iodine I 131 Tositumomab for Untreated Follicular Lymphoma
	John P. Leonard, Morton Coleman, Lale Kostakoglu, Amy Chadburn, Ethel Cesarman, Richard R. Furman, Michael W. Schuster, Ruben Niesvizky, Daniel Muss, Jennifer Fiore, Stewart Kroll, George Tidmarsh, Shankar Vallabhajosula, and Stanley J. Goldsmith
	JCO Aug 20 2005: 5696–5704. [Abstract] [Full Text] [PDF]
	Prognostic Factors and Outcome of Core Binding Factor Acute Myeloid Leukemia Patients With t(8;21) Differ From Those of Patients With inv(16): A Cancer and Leukemia Group B Study
	Guido Marcucci, Krzysztof Mrózek, Amy S. Ruppert, Kati Maharry, Jonathan E. Kolitz, Joseph O. Moore, Robert J. Mayer, Mark J. Pettenati, Bayard L. Powell, Colin G. Edwards, Lisa J. Sterling, James W. Vardiman, Charles A. Schiffer, Andrew J. Carroll, Richard A. Larson, and Clara D. Bloomfield
	JCO Aug 20 2005: 5705–5717. [Abstract] [Full Text] [PDF]
	Clinicopathologic and Genetic Profile of Intracranial Marginal Zone Lymphoma: A Primary Low-Grade CNS Lymphoma That Mimics Meningioma
	Pang-hsien Tu, Caterina Giannini, Alexander R. Judkins, Jason M. Schwalb, Richard Burack, Brian P. O'Neill, Anthony T. Yachnis, Peter C. Burger, Bernd W. Scheithauer, and Arie Perry
	JCO Aug 20 2005: 5718–5727. First published on Jul 11 2005; 10.1200/JCO.2005.17.624. [Abstract] [Full Text] [PDF]
	Fludarabine, Melphalan, and Alemtuzumab Conditioning in Adults With Standard-Risk Advanced Acute Myeloid Leukemia and Myelodysplastic Syndrome
	Koen van Besien, A. Artz, S. Smith, D. Cao, S. Rich, L. Godley, D. Jones, P. Del Cerro, D. Bennett, B. Casey, O. Odenike, M. Thirman, C. Daugherty, A. Wickrema, T. Zimmerman, R.A. Larson, and W. Stock
	JCO Aug 20 2005: 5728–5738. First published on Jul 11 2005; 10.1200/JCO.2005.15.602. [Abstract] [Full Text] [PDF]
	Lymphocyte-Rich Classical Hodgkin's Lymphoma: Clinical Presentation and Treatment Outcome in 100 Patients Treated Within German Hodgkin's Study Group Trials
	Alexander Shimabukuro-Vornhagen, Heinz Haverkamp, Andreas Engert, Leopold Balleisen, Peter Majunke, Günther Heil, Hans Theodor Eich, Harald Stein, Volker Diehl, and Andreas Josting
	JCO Aug 20 2005: 5739–5745. First published on Jul 11 2005; 10.1200/JCO.2005.17.970. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Polymorphisms in Inflammation Genes and Bladder Cancer: From Initiation to Recurrence, Progression, and Survival
	Dan Leibovici, H. Barton Grossman, Colin P. Dinney, Randal E. Millikan, Seth Lerner, Yunfei Wang, Jian Gu, Qiong Dong, and Xifeng Wu
	JCO Aug 20 2005: 5746–5756. [Abstract] [Full Text] [PDF]
	Increasing Incidence of Testicular Germ Cell Tumors Among Black Men in the United States
	Katherine A. McGlynn, Susan S. Devesa, Barry I. Graubard, and Philip E. Castle
	JCO Aug 20 2005: 5757–5761. [Abstract] [Full Text] [PDF]
	Modeling the Cost of Management Options for Stage I Nonseminomatous Germ Cell Tumors: A Decision Tree Analysis
	Richard E. Link, Mohamad E. Allaf, Roberto Pili, and Louis R. Kavoussi
	JCO Aug 20 2005: 5762–5773. [Abstract] [Full Text] [PDF] [Figure A1]

Lung Cancer
	Phase II Trial of the Novel Retinoid, Bexarotene, and Gemcitabine Plus Carboplatin in Advanced Non-Small-Cell Lung Cancer
	Martin J. Edelman, Ruth Smith, Petr Hausner, L. Austin Doyle, Kavita Kalra, Joyce Kendall, Michelle Bedor, and Sonia Bisaccia
	JCO Aug 20 2005: 5774–5778. [Abstract] [Full Text] [PDF]

Immunotherapy
	Immunomonitoring Tumor-Specific T Cells in Delayed-Type Hypersensitivity Skin Biopsies After Dendritic Cell Vaccination Correlates With Clinical Outcome
	I. Jolanda M. de Vries, Monique R. Bernsen, W. Joost Lesterhuis, Nicole M. Scharenborg, Simon P. Strijk, Marie-Jeanne P. Gerritsen, Dirk J. Ruiter, Carl G. Figdor, Cornelis J.A. Punt, and Gosse J. Adema
	JCO Aug 20 2005: 5779–5787. [Abstract] [Full Text] [PDF]

Bone Marrow Transplantation
	Unrelated Donor Marrow Transplantation for B-Cell Chronic Lymphocytic Leukemia After Using Myeloablative Conditioning: Results From the Center for International Blood and Marrow Transplant Research
	Steven Z. Pavletic, Issa F. Khouri, Michael Haagenson, Roberta J. King, Philip J. Bierman, Michael R. Bishop, Michael Carston, Sergio Giralt, Arturo Molina, Edward A. Copelan, Olle Ringdén, Vivek Roy, Karen Ballen, Douglas R. Adkins, Philip McCarthy, Daniel Weisdorf, Emili Montserrat, and Claudio Anasetti
	JCO Aug 20 2005: 5788–5794. First published on Jul 25 2005; 10.1200/JCO.2005.03.962. [Abstract] [Full Text] [PDF]

Sarcomas
	Initial and Late Resistance to Imatinib in Advanced Gastrointestinal Stromal Tumors Are Predicted by Different Prognostic Factors: A European Organisation for Research and Treatment of Cancer–Italian Sarcoma Group–Australasian Gastrointestinal Trials Group Study
	Martine Van Glabbeke, Jaap Verweij, Paolo G. Casali, Axel Le Cesne, Peter Hohenberger, Isabelle Ray-Coquard, Marcus Schlemmer, Allan T. van Oosterom, David Goldstein, Raf Sciot, Pancras C.W. Hogendoorn, Michelle Brown, Rossella Bertulli, and Ian R. Judson
	JCO Aug 20 2005: 5795–5804. [Abstract] [Full Text] [PDF]

Radiation Oncoloy
	Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients
	Isabelle Bairati, François Meyer, Michel Gélinas, André Fortin, Abdenour Nabid, François Brochet, Jean-Philippe Mercier, Bernard Têtu, François Harel, Belkacem Abdous, Éric Vigneault, Sylvie Vass, Pierre del Vecchio, and Jean Roy
	JCO Aug 20 2005: 5805–5813. First published on Jul 18 2005; 10.1200/JCO.2005.05.514. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Riding the Crest of the Teachable Moment: Promoting Long-Term Health After the Diagnosis of Cancer
	Wendy Demark-Wahnefried, Noreen M. Aziz, Julia H. Rowland, and Bernardine M. Pinto
	JCO Aug 20 2005: 5814–5830. First published on Jul 25 2005; 10.1200/JCO.2005.01.230. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLE
	Preliminary Data Release for Randomized Clinical Trials of Noninferiority: A New Proposal
	Edward L. Korn, Sally Hunsberger, Boris Freidlin, Malcolm A. Smith, and Jeffrey S. Abrams
	JCO Aug 20 2005: 5831–5836. First published on Jul 18 2005; 10.1200/JCO.2005.02.105. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Unusual Leukemia Presentations: CASE 1. Pulmonary Chloroma Preceded by Leukemia Cutis 7 Years Earlier

Claudia Lengerke, Stefan Wirths, Lothar Kanz, Holger Hebart, Edwin Kaiserling, Stefan M. Krober, Marius Stefan Horger, and Karsten Soennichsen

JCO Aug 20 2005: 5837–5839. [Full Text] [PDF]

Unusual Leukemia Presentations: CASE 2. Granulocytic Sarcoma of the Colon

Mohan Tummala, Leno Thomas, Christopher Gocke, Meyer R. Heyman, and Ivana Gojo

JCO Aug 20 2005: 5840–5841. [Full Text] [PDF]

Unusual Leukemia Presentations: CASE 3. Type I IgG Cryoglobulinemia Associated With Chronic Lymphocytic Leukemia

Simon Mantha, Michael I. Jacobs, and David G. Savage

JCO Aug 20 2005: 5841–5843. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Loss of Epidermal Growth Factor Receptor Expression in Lymph Node and Liver Metastases of Colon Carcinoma

Marie-Pierre Bralet, Bernard Paule, Rene Adam, and Catherine Guettier

JCO Aug 20 2005: 5844. [Full Text] [PDF]

In Reply:

Mario Scartozzi, Rossana Berardi, Italo Bearzi, and Stefano Cascinu

JCO Aug 20 2005: 5844-a–5855. [Full Text] [PDF]

Radiotherapeutic Prophylaxis of Gynecomastia

Daniel Thönnessen and Frederik Wenz

JCO Aug 20 2005: 5845. [Full Text] [PDF]

In Reply:

Francesco Boccardo and Alessandra Rubagotti

JCO Aug 20 2005: 5846. [Full Text] [PDF]

Limitations of Single-Strand Conformation Polymorphism Analysis As a High-Throughput Method for the Detection of EGFR Mutations in the Clinical Setting

Frank Weber, Koichi Fukino, Miguel Villalona-Calero, and Charis Eng

JCO Aug 20 2005: 5847–5848. [Full Text] [PDF]

In Reply:

Antonio Marchetti, Fabio Barassi, Lara Felicioni, Carla Martella, Simona Salvatore, Andrea Mezzetti, Franco Cuccurullo, Fiamma Buttitta, Antonio Chella, Pier P. Camplese, Teodorico Iarussi, Felice Mucilli, and Rocco Sacco

JCO Aug 20 2005: 5848–5849. [Full Text] [PDF]

Ewing’s Sarcoma of the Rectum: Are Four Cycles of Chemotherapy Enough?

Burak Sakar, Gul Basaran, and Mert Basaran

JCO Aug 20 2005: 5849–5850. [Full Text] [PDF] [Publisher's Note]

In Reply:

J. Vardy and S.J. Clarke

JCO Aug 20 2005: 5850. [Full Text] [PDF]

Errata

ERRATUM

JCO Aug 20 2005: 5851. [Full Text] [PDF]

ERRATUM

JCO Aug 20 2005: 5851-a. [Full Text] [PDF]

ERRATUM

JCO Aug 20 2005: 5851-b. [Full Text] [PDF]

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