EDITORIALS

A Point, a Line, or an Area? Which Is the Most Important in the Pharmacological Analysis of Cancer Chemotherapy?

Hironobu Minami

JCO Jan 20 2005: 405–406. First published on Dec 7 2004; 10.1200/JCO.2005.09.905. [Full Text] [PDF]

Period Analysis of Prostate Cancer Survival

George Wilding and Patrick Remington

JCO Jan 20 2005: 407–409. First published on Nov 30 2004; 10.1200/JCO.2005.09.906. [Full Text] [PDF]

Targeted for Destruction: The Molecular Basis for Development of Novel Therapeutic Strategies in Renal Cell Cancer

Ramaprasad Srinivasan and W. Marston Linehan

JCO Jan 20 2005: 410–412. First published on Nov 30 2004; 10.1200/JCO.2005.09.907. [Full Text] [PDF]

ORIGINAL REPORTS
Breast Cancer
	Model Describing the Relationship Between Pharmacokinetics and Hematologic Toxicity of the Epirubicin-Docetaxel Regimen in Breast Cancer Patients
	M. Sandström, H. Lindman, P. Nygren, E. Lidbrink, J. Bergh, and M.O. Karlsson
	JCO Jan 20 2005: 413–421. First published on Dec 7 2004; 10.1200/JCO.2005.09.161. [Abstract] [Full Text] [PDF]
	Prediction of Docetaxel Response in Human Breast Cancer by Gene Expression Profiling
	Kyoko Iwao-Koizumi, Ryo Matoba, Noriko Ueno, Seung Jin Kim, Akiko Ando, Yasuo Miyoshi, Eisaku Maeda, Shinzaburo Noguchi, and Kikuya Kato
	JCO Jan 20 2005: 422–431. [Abstract] [Full Text] [PDF]
	Up-Front Tandem High-Dose Chemotherapy Compared With Standard Chemotherapy With Doxorubicin and Paclitaxel in Metastatic Breast Cancer: Results of a Randomized Trial
	Peter Schmid, Walter Schippinger, Thorsten Nitsch, Gerdt Huebner, Volker Heilmann, Wolfgang Schultze, Hubert Hausmaninger, Manfred Wischnewsky, and Kurt Possinger
	JCO Jan 20 2005: 432–440. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Long-Term Survival Rates of Patients With Prostate Cancer in the Prostate-Specific Antigen Screening Era: Population-Based Estimates for the Year 2000 by Period Analysis
	Hermann Brenner and Volker Arndt
	JCO Jan 20 2005: 441–447. First published on Nov 30 2004; 10.1200/JCO.2005.11.148. [Abstract] [Full Text] [PDF]
	Downregulation of Smac/DIABLO Expression in Renal Cell Carcinoma and Its Prognostic Significance
	Yoichi Mizutani, Hiroyuki Nakanishi, Kosuke Yamamoto, Yong Nan Li, Hiroki Matsubara, Kazuya Mikami, Koji Okihara, Akihiro Kawauchi, Benjamin Bonavida, and Tsuneharu Miki
	JCO Jan 20 2005: 448–454. First published on Nov 30 2004; 10.1200/JCO.2005.02.191. [Abstract] [Full Text] [PDF]
	Randomized Phase II Study of Two Doses of Gefitinib in Hormone-Refractory Prostate Cancer: A Trial of the National Cancer Institute of Canada-Clinical Trials Group
	C.M. Canil, M.J. Moore, E. Winquist, T. Baetz, M. Pollak, K.N. Chi, S. Berry, D.S. Ernst, L. Douglas, M. Brundage, B. Fisher, A. McKenna, and L. Seymour
	JCO Jan 20 2005: 455–460. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Phase I Trial of Iodine-131 Tositumomab With High-Dose Chemotherapy and Autologous Stem-Cell Transplantation for Relapsed Non-Hodgkin's Lymphoma
	Julie M. Vose, Philip J. Bierman, Charles Enke, Jordan Hankins, Gregory Bociek, James C. Lynch, and James O. Armitage
	JCO Jan 20 2005: 461–467. First published on Nov 8 2004; 10.1200/JCO.2005.05.117. [Abstract] [Full Text] [PDF]
	Role of Anti-Hepatitis C Virus (HCV) Treatment in HCV-Related, Low-Grade, B-Cell, Non-Hodgkin's Lymphoma: A Multicenter Italian Experience
	Daniele Vallisa, Patrizia Bernuzzi, Luca Arcaini, Stefano Sacchi, Vittorio Callea, Roberto Marasca, Antonio Lazzaro, Elena Trabacchi, Elisa Anselmi, Anna Lisa Arcari, Carlo Moroni, Raffaella Bertè, Mario Lazzarino, and Luigi Cavanna
	JCO Jan 20 2005: 468–473. [Abstract] [Full Text] [PDF]
	Polymorphisms in FcRIIIA (CD16) Receptor Expression Are Associated With Clinical Response to Rituximab in Waldenström’s Macroglobulinemia
	Steven P. Treon, Mark Hansen, Andrew R. Branagan, Sigitas Verselis, Christos Emmanouilides, Eva Kimby, Stanley R. Frankel, Nikolaos Touroutoglou, Barry Turnbull, Kenneth C. Anderson, David G. Maloney, and Edward A. Fox
	JCO Jan 20 2005: 474–481. [Abstract] [Full Text] [PDF]
	Outcome of Induction and Postremission Therapy in Younger Adults With Acute Myeloid Leukemia With Normal Karyotype: A Cancer and Leukemia Group B Study
	Sherif S. Farag, Amy S. Ruppert, Krzysztof Mrózek, Robert J. Mayer, Richard M. Stone, Andrew J. Carroll, Bayard L. Powell, Joseph O. Moore, Mark J. Pettenati, Prasad R.K. Koduru, Judith Stamberg, Maria R. Baer, AnneMarie W. Block, James W. Vardiman, Jonathan E. Kolitz, Charles A. Schiffer, Richard A. Larson, and Clara D. Bloomfield
	JCO Jan 20 2005: 482–493. First published on Nov 8 2004; 10.1200/JCO.2005.06.090. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Docetaxel and Continuous-Infusion Fluorouracil Versus Epirubicin, Cisplatin, and Fluorouracil for Advanced Gastric Adenocarcinoma: A Randomized Phase II Study
	Peter C. Thuss-Patience, Albrecht Kretzschmar, Michael Repp, Dorothea Kingreen, Dirk Hennesser, Simone Micheel, Daniel Pink, Christian Scholz, Bernd Dörken, and Peter Reichardt
	JCO Jan 20 2005: 494–501. [Abstract] [Full Text] [PDF]
	Intensive Systemic Chemotherapy Combined With Surgery for Metastatic Colorectal Cancer: Results of a Phase II Study
	Julien Taïeb, Pascal Artru, François Paye, Christophe Louvet, Nathalie Perez, Thierry André, Brice Gayet, Mohamed Hebbar, Frédérique Maindrault Goebel, Christophe Tournigand, Rolland Parc, and Aimery de Gramont
	JCO Jan 20 2005: 502–509. [Abstract] [Full Text] [PDF]
	Racial Differences in Surgical Evaluation, Treatment, and Outcome of Locoregional Esophageal Cancer: A Population-Based Analysis of Elderly Patients
	Ewout W. Steyerberg, Craig C. Earle, Bridget A. Neville, and Jane C. Weeks
	JCO Jan 20 2005: 510–517. [Abstract] [Full Text] [PDF]

Melanoma
	Prognostic Implications of Multiple Lymphatic Basin Drainage in Patients With Truncal Melanoma
	Ramon E. Jimenez, Katherine Panageas, Klaus J. Busam, and Mary S. Brady
	JCO Jan 20 2005: 518–524. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Phase I Clinical Trial of Mafosfamide in Infants and Children Aged 3 Years or Younger With Newly Diagnosed Embryonal Tumors: A Pediatric Brain Tumor Consortium Study (PBTC-001)
	Susan M. Blaney, James Boyett, Henry Friedman, Amar Gajjar, Russ Geyer, Marc Horowtiz, Daniel Hunt, Mark Kieran, Larry Kun, Roger Packer, Peter Phillips, Ian F. Pollack, Michael Prados, and Richard Heideman
	JCO Jan 20 2005: 525–531. [Abstract] [Full Text] [PDF]
	Results of Induction Chemotherapy in Children Older Than 1 Year With a Stage 4 Neuroblastoma Treated With the NB 97 French Society of Pediatric Oncology (SFOP) Protocol
	Dominique Valteau-Couanet, Jean Michon, Andrée Boneu, Chantal Rodary, Yves Perel, Christophe Bergeron, Hervé Rubie, Carole Coze, Dominique Plantaz, Frédéric Bernard, Pascal Chastagner, Jeannine Bouzy, and Olivier Hartmann
	JCO Jan 20 2005: 532–540. [Abstract] [Full Text] [PDF]
	Advanced-Stage Large-Cell Lymphoma in Children and Adolescents: Results of a Randomized Trial Incorporating Intermediate-Dose Methotrexate and High-Dose Cytarabine in the Maintenance Phase of the APO Regimen: A Pediatric Oncology Group Phase III Trial
	Joseph H. Laver, Jacqueline M. Kraveka, Robert E. Hutchison, Myron Chang, James Kepner, Molly Schwenn, Nancy Tarbell, Sunil Desai, Sheila Weitzman, Howard J. Weinstein, and Sharon B. Murphy
	JCO Jan 20 2005: 541–547. [Abstract] [Full Text] [PDF]
	Ewing Sarcomas With p53 Mutation or p16/p14ARF Homozygous Deletion: A Highly Lethal Subset Associated With Poor Chemoresponse
	Hsuan-Ying Huang, Peter B. Illei, Zhiquan Zhao, Madhu Mazumdar, Andrew G. Huvos, John H. Healey, Leonard H. Wexler, Richard Gorlick, Paul Meyers, and Marc Ladanyi
	JCO Jan 20 2005: 548–558. [Abstract] [Full Text] [PDF]
	Osteosarcoma Relapse After Combined Modality Therapy: An Analysis of Unselected Patients in the Cooperative Osteosarcoma Study Group (COSS)
	Beate Kempf-Bielack, Stefan S. Bielack, Heribert Jürgens, Detlev Branscheid, Wolfgang E. Berdel, G. Ulrich Exner, Ulrich Göbel, Knut Helmke, Gernot Jundt, Hartmut Kabisch, Mathias Kevric, Thomas Klingebiel, Rainer Kotz, Rainer Maas, Rudolf Schwarz, Michael Semik, Jörn Treuner, Andreas Zoubek, and Kurt Winkler
	JCO Jan 20 2005: 559–568. [Abstract] [Full Text] [PDF]

Lung Cancer
	Platinum-Etoposide Chemotherapy in Elderly Patients With Small-Cell Lung Cancer: Results of a Randomized Multicenter Phase II Study Assessing Attenuated-Dose or Full-Dose With Lenograstim Prophylaxis—A Forza Operativa Nazionale Italiana Carcinoma Polmonare and Gruppo Studio Tumori Polmonari Veneto (FONICAP-GSTPV) Study
	Andrea Ardizzoni, Adolfo Favaretto, Luca Boni, Editta Baldini, Federico Castiglioni, Paola Antonelli, Franca Pari, Carmelo Tibaldi, Alfonso M. Altieri, Sante Barbera, Giancarlo Cacciani, Mario Raimondi, Lucia Tixi, Micaela Stefani, Silvio Monfardini, Antonio Antilli, Riccardo Rosso, and Adriano Paccagnella
	JCO Jan 20 2005: 569–575. [Abstract] [Full Text] [PDF]

Sarcomas
	Phase II Study of ET-743 in Advanced Soft Tissue Sarcomas: A European Organisation for the Research and Treatment of Cancer (EORTC) Soft Tissue and Bone Sarcoma Group Trial
	A. Le Cesne, J.Y. Blay, I. Judson, A. Van Oosterom, J. Verweij, J. Radford, P. Lorigan, S. Rodenhuis, I. Ray-Coquard, S. Bonvalot, F. Collin, J. Jimeno, E. Di Paola, M. Van Glabbeke, and O.S. Nielsen
	JCO Jan 20 2005: 576–584. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Imatinib Mesylate in Patients With Adenoid Cystic Cancers of the Salivary Glands Expressing c-kit: A Princess Margaret Hospital Phase II Consortium Study
	Sébastien J. Hotte, Eric W. Winquist, Elizabeth Lamont, Mary MacKenzie, Everett Vokes, Eric X. Chen, Shirley Brown, Gregory R. Pond, Anthony Murgo, and Lillian L. Siu
	JCO Jan 20 2005: 585–590. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Quality-of-Life Assessment in the Symptom Management Trials of the National Cancer Institute-Supported Community Clinical Oncology Program
	David R. Buchanan, Ann M. O'Mara, Joseph W. Kelaghan, and Lori M. Minasian
	JCO Jan 20 2005: 591–598. [Abstract] [Full Text] [PDF]
	Long-Term Health-Related Quality of Life, Growth, and Spiritual Well-Being After Hematopoietic Stem-Cell Transplantation
	Michael A. Andrykowski, Michelle M. Bishop, Elizabeth A. Hahn, David F. Cella, Jennifer L. Beaumont, Marianne J. Brady, Mary M. Horowitz, Kathleen A. Sobocinski, J. Douglas Rizzo, and John R. Wingard
	JCO Jan 20 2005: 599–608. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis
	S. Popat, R. Hubner, and R.S. Houlston
	JCO Jan 20 2005: 609–618. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLE
	American Society of Clinical Oncology Technology Assessment on the Use of Aromatase Inhibitors As Adjuvant Therapy for Postmenopausal Women With Hormone Receptor–Positive Breast Cancer: Status Report 2004
	Eric P. Winer, Clifford Hudis, Harold J. Burstein, Antonio C. Wolff, Kathleen I. Pritchard, James N. Ingle, Rowan T. Chlebowski, Richard Gelber, Stephan B. Edge, Julie Gralow, Melody A. Cobleigh, Eleftherios P. Mamounas, Lori J. Goldstein, Timothy J. Whelan, Trevor J. Powles, John Bryant, Cheryl Perkins, Judy Perotti, Susan Braun, Amy S. Langer, George P. Browman, and Mark R. Somerfield
	JCO Jan 20 2005: 619–629. First published on Nov 15 2004; 10.1200/JCO.2005.09.121. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Proteasome Inhibition As a Novel Therapeutic Target in Human Cancer
	S. Vincent Rajkumar, Paul G. Richardson, Teru Hideshima, and Kenneth C. Anderson
	JCO Jan 20 2005: 630–639. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Benign Lesions in Cancer Patients: CASE 1. Sarcoidosis After Chemoradiation for Head and Neck Cancer

Min Yao, Gerry F. Funk, David P. Goldstein, Barry R. DeYoung, and Michael M. Graham

JCO Jan 20 2005: 640–641. [Full Text] [PDF]

Benign Lesions in Cancer Patients: CASE 2. Unusual Association of Osteosarcoma and Sarcoidosis

Kyoji Okada, Masahiro Sasaki, Hiroshi Nanjo, Manabu Ito, Shu Takahashi, and Eiji Itoi

JCO Jan 20 2005: 641–643. [Full Text] [PDF]

Benign Lesions in Cancer Patients: CASE 3. Vitiligo After Radiotherapy for Breast Cancer in a Woman With Depigmentation Disorder

Rony Weitzen, Raphael Pfeffer, and Matilda Mandel

JCO Jan 20 2005: 644. [Full Text] [PDF]

ART OF ONCOLOGY

Humor and Oncology

Anthony M. Joshua, Angela Cotroneo, and Stephen Clarke

JCO Jan 20 2005: 645–648. [Full Text] [PDF]

SPECIAL DEPARTMENTS

Correspondence

Antiapoptotic Effect of Growth Factors in Leukemia

Wai M. Liu, Richard Baird, Debashis Sarker, and Thomas Powles

JCO Jan 20 2005: 649. [Full Text] [PDF]

In Reply:

Olle Ringdén

JCO Jan 20 2005: 649-a–650. [Full Text] [PDF]

Relationship of Serum Bilirubin to Toxicity in Patients With Metastatic Colorectal Cancer Treated With Single-Agent High-Dose Irinotecan

Andrew Kramar, Sophie Gourgou-Bourgade, and Marc Ychou

JCO Jan 20 2005: 650. [Full Text] [PDF]

In Reply:

Jeffrey A. Meyerhardt and Charles S. Fuchs

JCO Jan 20 2005: 650-a–651. [Full Text] [PDF]

Intravenous Iron and Recombinant Human Erythropoietin in Cancer Patients

Yves Beguin

JCO Jan 20 2005: 651–652. [Full Text] [PDF]

In Reply:

Michael Auerbach and Harold Ballard

JCO Jan 20 2005: 652–653. [Full Text] [PDF]

Re: Pooled Analysis of Fluorouracil-Based Adjuvant Therapy of Stage II and III Colon Cancer: Who Benefits and by How Much?

Hany Elsaleh and Barry Iacopetta

JCO Jan 20 2005: 653–654. [Full Text] [PDF]

In Reply

Steven R. Alberts, Daniel J. Sargent, Sharlene Gill, and Charles L. Loprinzi

JCO Jan 20 2005: 654–655. [Full Text] [PDF]

Neoadjuvant Chemotherapy Followed by Extrapleural Pneumonectomy in Malignant Pleural Mesothelioma: Is It Safe?

Güngör Utkan, Bülent Yalçin, Abdullah Büyükçelik, and Samet Yalçin

JCO Jan 20 2005: 655. [Full Text] [PDF]

In Reply

Walter Weder

JCO Jan 20 2005: 655-a. [Full Text] [PDF]

Errata

Erratum

JCO Jan 20 2005: 656. [Full Text] [PDF]

Erratum

JCO Jan 20 2005: 656-a. [Full Text] [PDF]

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