EDITORIALS

Functional Analysis of the Breast Cancer Genome

Matthew J. Ellis

JCO Apr 10 2006: 1649–1650. First published on Feb 27 2006; 10.1200/JCO.2005.05.3520. [Full Text] [PDF]

Genetic Susceptibility to Lung Cancer

David C. Christiani

JCO Apr 10 2006: 1651–1652. First published on Mar 20 2006; 10.1200/JCO.2005.05.4114. [Full Text] [PDF]

Medullary Thyroid Cancer: Options for Systemic Therapy of Metastatic Disease?

Renato G. Martins, Joseph G. Rajendran, Peter Capell, David R. Byrd, and David A. Mankoff

JCO Apr 10 2006: 1653–1655. First published on Mar 20 2006; 10.1200/JCO.2005.05.4106. [Full Text] [PDF]

ORIGINAL REPORTS
Breast Cancer
	Estrogen-Regulated Genes Predict Survival in Hormone Receptor–Positive Breast Cancers
	Daniel S. Oh, Melissa A. Troester, Jerry Usary, Zhiyuan Hu, Xiaping He, Cheng Fan, Junyuan Wu, Lisa A. Carey, and Charles M. Perou
	JCO Apr 10 2006: 1656–1664. First published on Feb 27 2006; 10.1200/JCO.2005.03.2755. [Abstract] [Full Text] [PDF] [Supplementary Data]
	Multicenter Validation of a Gene Expression–Based Prognostic Signature in Lymph Node–Negative Primary Breast Cancer
	John A. Foekens, David Atkins, Yi Zhang, Fred C.G.J. Sweep, Nadia Harbeck, Angelo Paradiso, Tanja Cufer, Anieta M. Sieuwerts, Dmitri Talantov, Paul N. Span, Vivianne C.G. Tjan-Heijnen, Alfredo F. Zito, Katja Specht, Heinz Hoefler, Rastko Golouh, Francesco Schittulli, Manfred Schmitt, Louk V.A.M. Beex, Jan G.M. Klijn, and Yixin Wang
	JCO Apr 10 2006: 1665–1671. First published on Feb 27 2006; 10.1200/JCO.2005.03.9115. [Abstract] [Full Text] [PDF]

Lung Cancer
	Association of the PDCD5 Locus With Lung Cancer Risk and Prognosis in Smokers
	Monica Spinola, Peter Meyer, Stefan Kammerer, F. Stefania Falvella, Melanie B. Boettger, Carolyn R. Hoyal, Carmen Pignatiello, Reiner Fischer, Richard B. Roth, Ugo Pastorino, Karl Haeussinger, Matthew R. Nelson, Rainer Dierkesmann, Tommaso A. Dragani, and Andreas Braun
	JCO Apr 10 2006: 1672–1678. First published on Mar 20 2006; 10.1200/JCO.2005.04.4339. [Abstract] [Full Text] [PDF]
	Expression Profile–Defined Classification of Lung Adenocarcinoma Shows Close Relationship With Underlying Major Genetic Changes and Clinicopathologic Behaviors
	Toshiyuki Takeuchi, Shuta Tomida, Yasushi Yatabe, Takayuki Kosaka, Hirotaka Osada, Kiyoshi Yanagisawa, Tetsuya Mitsudomi, and Takashi Takahashi
	JCO Apr 10 2006: 1679–1688. First published on Mar 20 2006; 10.1200/JCO.2005.03.8224. [Abstract] [Full Text] [PDF] [Supplementary Data]
	Multicenter Phase I Study of Repeated Intratumoral Delivery of Adenoviral p53 in Patients With Advanced Non–Small-Cell Lung Cancer
	Toshiyoshi Fujiwara, Noriaki Tanaka, Susumu Kanazawa, Shoichiro Ohtani, Yasuo Saijo, Toshihiro Nukiwa, Kunihiko Yoshimura, Tetsuo Sato, Yoshikatsu Eto, Sunil Chada, Haruhiko Nakamura, and Harubumi Kato
	JCO Apr 10 2006: 1689–1699. First published on Feb 27 2006; 10.1200/JCO.2005.03.4116. [Abstract] [Full Text] [PDF]
	Use of Cigarette-Smoking History to Estimate the Likelihood of Mutations in Epidermal Growth Factor Receptor Gene Exons 19 and 21 in Lung Adenocarcinomas
	DuyKhanh Pham, Mark G. Kris, Gregory J. Riely, Inderpal S. Sarkaria, Tiffani McDonough, Shaokun Chuai, Ennapadam S. Venkatraman, Vincent A. Miller, Marc Ladanyi, William Pao, Richard K. Wilson, Bhuvanesh Singh, and Valerie W. Rusch
	JCO Apr 10 2006: 1700–1704. First published on Feb 27 2006; 10.1200/JCO.2005.04.3224. [Abstract] [Full Text] [PDF]

Clinical Trials
	Survival Improvement in Patients With Medullary Thyroid Carcinoma Who Undergo Pretargeted Anti–Carcinoembryonic-Antigen Radioimmunotherapy: A Collaborative Study With the French Endocrine Tumor Group
	Jean-François Chatal, Loïc Campion, Françoise Kraeber-Bodéré, Stephane Bardet, Jean-Philippe Vuillez, Bernard Charbonnel, Vincent Rohmer, Chien-Hsing Chang, Robert M. Sharkey, David M. Goldenberg, and Jacques Barbet
	JCO Apr 10 2006: 1705–1711. First published on Mar 20 2006; 10.1200/JCO.2005.04.4917. [Abstract] [Full Text] [PDF]

Phase I and Clinical Pharmacology
	Phase I Study of Antisense Oligonucleotide Against Vascular Endothelial Growth Factor: Decrease in Plasma Vascular Endothelial Growth Factor With Potential Clinical Efficacy
	Alexandra M. Levine, Anil Tulpule, David I. Quinn, Gerardo Gorospe, III, D. Lynne Smith, Laurie Hornor, William D. Boswell, Byron M. Espina, Susan G. Groshen, Rizwan Masood, and Parkash S. Gill
	JCO Apr 10 2006: 1712–1719. First published on Mar 6 2006; 10.1200/JCO.2005.03.4801. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Single Nucleotide Polymorphisms of RecQ1, RAD54L, and ATM Genes Are Associated With Reduced Survival of Pancreatic Cancer
	Donghui Li, Marsha Frazier, Douglas B. Evans, Kenneth R. Hess, Christopher H. Crane, Li Jiao, and James L. Abbruzzese
	JCO Apr 10 2006: 1720–1728. First published on Mar 6 2006; 10.1200/JCO.2005.04.4206. [Abstract] [Full Text] [PDF]

Molecular Oncology
	Tumor Transcriptome Reveals the Predictive and Prognostic Impact of Lysosomal Protease Inhibitors in Non–Small-Cell Lung Cancer
	Russell D. Petty, Keith M. Kerr, Graeme I. Murray, Marianne C. Nicolson, Patrick H. Rooney, Donald Bissett, and Elaina S.R. Collie-Duguid
	JCO Apr 10 2006: 1729–1744. First published on Mar 20 2006; 10.1200/JCO.2005.03.3399. [Abstract] [Full Text] [PDF] [Supplementary Data]

Gynecologic Cancer
	Clinicopathologic Significance of Defective DNA Mismatch Repair in Endometrial Carcinoma
	Destin Black, Robert A. Soslow, Douglas A. Levine, Carmen Tornos, Shirley C. Chen, Amanda J. Hummer, Faina Bogomolniy, Narciso Olvera, Richard R. Barakat, and Jeff Boyd
	JCO Apr 10 2006: 1745–1753. First published on Mar 20 2006; 10.1200/JCO.2005.04.1574. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Serum Circulating Human mRNA Profiling and Its Utility for Oral Cancer Detection
	Yang Li, David Elashoff, Myungshin Oh, Uttam Sinha, Maie A.R. St John, Xiaofeng Zhou, Elliot Abemayor, and David T. Wong
	JCO Apr 10 2006: 1754–1760. First published on Feb 27 2006; 10.1200/JCO.2005.03.7598. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Role of the Glutathione Metabolic Pathway in Lung Cancer Treatment and Prognosis: A Review
	Ping Yang, Jon O. Ebbert, Zhifu Sun, and Richard M. Weinshilboum
	JCO Apr 10 2006: 1761–1769. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Cyclin-Dependent Kinase Pathways As Targets for Cancer Treatment
	Geoffrey I. Shapiro
	JCO Apr 10 2006: 1770–1783. [Abstract] [Full Text] [PDF]

ERRATA

ERRATUM

JCO Apr 10 2006: 1784. [Full Text] [PDF]

ERRATUM

JCO Apr 10 2006: 1784-a. [Full Text] [PDF]

ERRATUM

JCO Apr 10 2006: 1784-b. [Full Text] [PDF]

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