EDITORIALS

Thoracic Radiation Therapy in Limited Stage Small-Cell Lung Cancer: Timing Is Everything...Isn't It?

Michael C. Perry

JCO Aug 20 2006: 3815–3816. [Full Text] [PDF]

Neoadjuvant Chemotherapy for Disseminated Colorectal Cancer: Changing the Paradigm

Lawrence Leichman

JCO Aug 20 2006: 3817–3818. [Full Text] [PDF]

Are Nomograms Better Than Currently Available Stage Groupings for Bladder Cancer?

Cora N. Sternberg

JCO Aug 20 2006: 3819–3820. First published on Jul 24 2006; 10.1200/JCO.2006.07.1290. [Full Text] [PDF]

Some Thoughts on the Reporting of Adverse Events in Phase II Cancer Clinical Trials

Stewart J. Anderson

JCO Aug 20 2006: 3821–3822. [Full Text] [PDF]

ORIGINAL REPORTS
Lung Cancer
	Early Compared With Late Radiotherapy in Combined Modality Treatment for Limited Disease Small-Cell Lung Cancer: A London Lung Cancer Group Multicenter Randomized Clinical Trial and Meta-Analysis
	Stephen G. Spiro, Lindsay E. James, Robin M. Rudd, Colin W. Trask, Jeffrey S. Tobias, Michael Snee, David Gilligan, Philip A. Murray, Mary Carmen Ruiz de Elvira, Katy M. O'Donnell, Nicole H. Gower, Peter G. Harper, and Allan K. Hackshaw
	JCO Aug 20 2006: 3823–3830. [Abstract] [Full Text] [PDF]
	Symptom Improvement in Lung Cancer Patients Treated With Erlotinib: Quality of Life Analysis of the National Cancer Institute of Canada Clinical Trials Group Study BR.21
	Andrea Bezjak, Dongsheng Tu, Lesley Seymour, Gary Clark, Aleksandra Trajkovic, Mauro Zukin, Joseph Ayoub, Sergio Lago, Ronaldo de Albuquerque Ribeiro, Alexandra Gerogianni, Arnold Cyjon, Jonathan Noble, Francis Laberge, Raymond Tsz-Tong Chan, David Fenton, Joachim von Pawel, Martin Reck, and Frances A. Shepherd
	JCO Aug 20 2006: 3831–3837. [Abstract] [Full Text] [PDF] [Publisher's Note]

Pediatric Oncology
	Local Control in Pelvic Ewing Sarcoma: Analysis From INT-0091—A Report From the Children's Oncology Group
	Torunn I. Yock, Mark Krailo, Christopher J. Fryer, Sarah S. Donaldson, James S. Miser, Zhengjia Chen, Mark Bernstein, Fran Laurie, Mark. C. Gebhardt, Holcombe E. Grier, and Nancy J. Tarbell
	JCO Aug 20 2006: 3838–3843. [Abstract] [Full Text] [PDF]
	Analysis of Prognostic Factors in Patients With Nonmetastatic Rhabdomyosarcoma Treated on Intergroup Rhabdomyosarcoma Studies III and IV: The Children's Oncology Group
	Jane L. Meza, James Anderson, Alberto S. Pappo, and William H. Meyer
	JCO Aug 20 2006: 3844–3851. [Abstract] [Full Text] [PDF]
	Suicidal Ideation and Attempts in Adult Survivors of Childhood Cancer
	Christopher J. Recklitis, Rebecca A. Lockwood, Monica A. Rothwell, and Lisa R. Diller
	JCO Aug 20 2006: 3852–3857. [Abstract] [Full Text] [PDF]
	Comparison of Long-Term Neurocognitive Outcomes in Young Children With Acute Lymphoblastic Leukemia Treated With Cranial Radiation or High-Dose or Very High-Dose Intravenous Methotrexate
	Brenda J. Spiegler, Kimberly Kennedy, Ronnen Maze, Mark L. Greenberg, Sheila Weitzman, Johann K. Hitzler, and Paul C. Nathan
	JCO Aug 20 2006: 3858–3864. [Abstract] [Full Text] [PDF] [Publisher's Note]

Neurooncology
	High-Dose Chemotherapy With Autologous Stem-Cell Transplantation and Hyperfractionated Radiotherapy As First-Line Treatment of Primary CNS Lymphoma
	Gerald Illerhaus, Reinhard Marks, Gabriele Ihorst, Roland Guttenberger, Christoph Ostertag, Günther Derigs, Norbert Frickhofen, Friedrich Feuerhake, Benedikt Volk, and Jürgen Finke
	JCO Aug 20 2006: 3865–3870. First published on Jul 24 2006; 10.1200/JCO.2006.06.2117. [Abstract] [Full Text] [PDF]
	Phase III Trial of Carmustine and Cisplatin Compared With Carmustine Alone and Standard Radiation Therapy or Accelerated Radiation Therapy in Patients With Glioblastoma Multiforme: North Central Cancer Treatment Group 93-72-52 and Southwest Oncology Group 9503 Trials
	Jan C. Buckner, Karla V. Ballman, John C. Michalak, Gary V. Burton, Terrence L. Cascino, Paula J. Schomberg, Roland B. Hawkins, Bernd W. Scheithauer, Howard M. Sandler, Randolph S. Marks, and Judith R. O'Fallon
	JCO Aug 20 2006: 3871–3879. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Multicenter Phase II Trial of Immunotherapy With the Humanized Anti-CD22 Antibody, Epratuzumab, in Combination With Rituximab, in Refractory or Recurrent Non-Hodgkin's Lymphoma
	Sandra J. Strauss, Frank Morschhauser, Juergen Rech, Roland Repp, Philippe Solal-Celigny, Pier L. Zinzani, Andreas Engert, Bernard Coiffier, Dieter F. Hoelzer, William A. Wegener, Nick K.W. Teoh, David M. Goldenberg, and T. Andrew Lister
	JCO Aug 20 2006: 3880–3886. First published on Jul 24 2006; 10.1200/JCO.2006.05.6291. [Abstract] [Full Text] [PDF]
	Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using Microarray-Based Molecular Characterization
	Frank G. Rücker, Lars Bullinger, Carsten Schwaenen, Daniel B. Lipka, Swen Wessendorf, Stefan Fröhling, Martin Bentz, Simone Miller, Claudia Scholl, Richard F. Schlenk, Bernhard Radlwimmer, Hans A. Kestler, Jonathan R. Pollack, Peter Lichter, Konstanze Döhner, and Hartmut Döhner
	JCO Aug 20 2006: 3887–3894. First published on Jul 24 2006; 10.1200/JCO.2005.04.5450. [Abstract] [Full Text] [PDF] [Supplementary Material]
	Further Analysis of Trials With Azacitidine in Patients With Myelodysplastic Syndrome: Studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B
	Lewis R. Silverman, David R. McKenzie, Bercedis L. Peterson, James F. Holland, Jay T. Backstrom, C.L. Beach, and Richard A. Larson
	JCO Aug 20 2006: 3895–3903. [Abstract] [Full Text] [PDF]
	Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study
	Peter Paschka, Guido Marcucci, Amy S. Ruppert, Krzysztof Mrózek, Hankui Chen, Rick A. Kittles, Tamara Vukosavljevic, Danilo Perrotti, James W. Vardiman, Andrew J. Carroll, Jonathan E. Kolitz, Richard A. Larson, and Clara D. Bloomfield
	JCO Aug 20 2006: 3904–3911. [Abstract] [Full Text] [PDF]

Breast Cancer
	Lack of Benefit of Maintenance Paclitaxel in First-Line Chemotherapy in Metastatic Breast Cancer
	Alessandra Gennari, Dino Amadori, Mario De Lena, Oriana Nanni, Paolo Bruzzi, Vito Lorusso, Luigi Manzione, and Pier Franco Conte
	JCO Aug 20 2006: 3912–3918. [Abstract] [Full Text] [PDF]
	Randomized Trial of Single Compared With Tandem High-Dose Chemotherapy Followed by Autologous Stem-Cell Transplantation in Patients With Chemotherapy-Sensitive Metastatic Breast Cancer
	Nicolaus Kröger, Markus Frick, Oleg Gluz, Svjetlana Mohrmann, Bernd Metzner, Christian Jackisch, Yon Ko, Hans-Walter Lindemann, Carl Richard Meier, Hans Peter Lohrmann, Ute Ruffert, Matthias Hänel, Heinrich Bodenstein, Andreas Neubauer, Gerhard Ehninger, Hans-Heinrich Wolf, Kathrin Kolbe, Karin Burock, Axel R. Zander, and Ulrike Nitz
	JCO Aug 20 2006: 3919–3926. [Abstract] [Full Text] [PDF]
	Low Locoregional Recurrence Rate Among Node-Negative Breast Cancer Patients With Tumors 5 cm or Larger Treated by Mastectomy, With or Without Adjuvant Systemic Therapy and Without Radiotherapy: Results From Five National Surgical Adjuvant Breast and Bowel Project Randomized Clinical Trials
	Alphonse G. Taghian, Jong-Hyeon Jeong, Eleftherios P. Mamounas, David S. Parda, Melvin Deutsch, Joseph P. Costantino, and Norman Wolmark
	JCO Aug 20 2006: 3927–3932. [Abstract] [Full Text] [PDF]

Clinical Trials
	Adverse Event Reporting in Publications Compared With Sponsor Database for Cancer Clinical Trials
	Orit Scharf and A. Dimitrios Colevas
	JCO Aug 20 2006: 3933–3938. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Complete Response of Colorectal Liver Metastases After Chemotherapy: Does It Mean Cure?
	Stéphane Benoist, Antoine Brouquet, Christophe Penna, Catherine Julié, Mostafa El Hajjam, Sophie Chagnon, Emmanuel Mitry, Philippe Rougier, and Bernard Nordlinger
	JCO Aug 20 2006: 3939–3945. [Abstract] [Full Text] [PDF]
	Randomized Phase III Trial of Gemcitabine Plus Cisplatin Compared With Gemcitabine Alone in Advanced Pancreatic Cancer
	Volker Heinemann, Detlef Quietzsch, Frank Gieseler, Michael Gonnermann, Herbert Schönekäs, Andreas Rost, Horst Neuhaus, Caroline Haag, Michael Clemens, Bernard Heinrich, Ursula Vehling-Kaiser, Martin Fuchs, Doris Fleckenstein, Wolfgang Gesierich, Dirk Uthgenannt, Hermann Einsele, Axel Holstege, Axel Hinke, Andreas Schalhorn, and Ralf Wilkowski
	JCO Aug 20 2006: 3946–3952. [Abstract] [Full Text] [PDF]
	Phase II Trial of Preoperative Chemoradiation in Patients With Localized Gastric Adenocarcinoma (RTOG 9904): Quality of Combined Modality Therapy and Pathologic Response
	Jaffer A. Ajani, Kathryn Winter, Gordon S. Okawara, John H. Donohue, Peter W.T. Pisters, Christopher H. Crane, John F. Greskovich, P. Rani Anne, Jeffrey D. Bradley, Christopher Willett, and Tyvin A. Rich
	JCO Aug 20 2006: 3953–3958. [Abstract] [Full Text] [PDF] [Spanish PDF]

Bone Marrow Transplantation
	Results of Genoidentical Hemopoietic Stem Cell Transplantation With Reduced Intensity Conditioning for Acute Myelocytic Leukemia: Higher Doses of Stem Cells Infused Benefit Patients Receiving Transplants in Second Remission or Beyond—The Acute Leukemia Working Party of the European Cooperative Group for Blood and Marrow Transplantation
	Norbert-Claude Gorin, Myriam Labopin, Jean-Michel Boiron, Niklas Theorin, Tim Littlewood, Shimon Slavin, Hildegard Greinix, Jean Yves Cahn, E. Paolo Alessandrino, Alessandro Rambaldi, Arnon Nagler, Emmanuelle Polge, and Vanderson Rocha
	JCO Aug 20 2006: 3959–3966. First published on Jul 31 2006; 10.1200/JCO.2006.05.5855. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Postoperative Nomogram Predicting Risk of Recurrence After Radical Cystectomy for Bladder Cancer
	International Bladder Cancer Nomogram Consortium
	JCO Aug 20 2006: 3967–3972. First published on Jul 24 2006; 10.1200/JCO.2005.05.3884. [Abstract] [Full Text] [PDF]
	Defining Biochemical Recurrence of Prostate Cancer After Radical Prostatectomy: A Proposal for a Standardized Definition
	Andrew J. Stephenson, Michael W. Kattan, James A. Eastham, Zohar A. Dotan, Fernando J. Bianco, Jr, Hans Lilja, and Peter T. Scardino
	JCO Aug 20 2006: 3973–3978. [Abstract] [Full Text] [PDF]
	Metabolic Syndrome in Men With Prostate Cancer Undergoing Long-Term Androgen-Deprivation Therapy
	Milena Braga-Basaria, Adrian S. Dobs, Denis C. Muller, Michael A. Carducci, Majnu John, Josephine Egan, and Shehzad Basaria
	JCO Aug 20 2006: 3979–3983. [Abstract] [Full Text] [PDF]
	Absolute Prostate-Specific Antigen Value After Androgen Deprivation Is a Strong Independent Predictor of Survival in New Metastatic Prostate Cancer: Data From Southwest Oncology Group Trial 9346 (INT-0162)
	Maha Hussain, Catherine M. Tangen, Celestia Higano, Paul F. Schelhammer, James Faulkner, E. David Crawford, George Wilding, Atif Akdas, Eric J. Small, Bryan Donnelly, Gary MacVicar, and Derek Raghavan
	JCO Aug 20 2006: 3984–3990. [Abstract] [Full Text] [PDF]

Prevention
	Influence of Hormone Replacement Therapy on Tamoxifen-Induced Vasomotor Symptoms
	Ivana Sestak, Roseann Kealy, Robert Edwards, John Forbes, and Jack Cuzick
	JCO Aug 20 2006: 3991–3996. [Abstract] [Full Text] [PDF]

Sarcomas
	Impact of High-Dose Busulfan Plus Melphalan As Consolidation in Metastatic Ewing Tumors: A Study by the Société Française des Cancers de l'Enfant
	Odile Oberlin, Annie Rey, Anne Sophie Desfachelles, Thierry Philip, Dominique Plantaz, Claudine Schmitt, Emmanuel Plouvier, Odile Lejars, Hervé Rubie, Philippe Terrier, and Jean Michon
	JCO Aug 20 2006: 3997–4002. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Prognosis of Critically Ill Patients With Cancer and Acute Renal Dysfunction
	Márcio Soares, Jorge I.F. Salluh, Marilia S. Carvalho, Michael Darmon, José R. Rocco, and Nelson Spector
	JCO Aug 20 2006: 4003–4010. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Systematic Review on the Efficacy of Cytoreductive Surgery Combined With Perioperative Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis From Colorectal Carcinoma
	Tristan D. Yan, Deborah Black, Renaldo Savady, and Paul H. Sugarbaker
	JCO Aug 20 2006: 4011–4019. [Abstract] [Full Text] [PDF]

SPECIAL ARTICLE
	Shaping Your Career to Maximize Personal Satisfaction in the Practice of Oncology
	Tait Shanafelt, Harold Chung, Heather White, and Laurie Jean Lyckholm
	JCO Aug 20 2006: 4020–4026. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Isolated Splenic Sinus Histiocytosis (Rosai-Dorfman disease) in Association With Myelodysplastic Syndrome

Stacey K. Knox, Paul J. Kurtin, and David P. Steensma

JCO Aug 20 2006: 4027–4028. [Full Text] [PDF]

Isolated Blast Crisis in CNS in a Patient With Chronic Myelogenous Leukemia Maintaining Major Cytogenetic Response After Imatinib

Hyun Jung Kim, Chul Won Jung, Kihyun Kim, Jin Seok Ahn, Won Seog Kim, Kwan Park, Young Hye Ko, Won Ki Kang, and Keunchil Park

JCO Aug 20 2006: 4028–4029. [Full Text] [PDF]

Azygo-Tracheal Fistula in a Complete Implantable Central Venous System

Carlo Cosimo Quattrocchi, Matteo Sammarra, Massimiliano Carassiti, Bruno Vincenzi, Giuseppe Tonini, Rosario Francesco Grasso, and Bruno Beomonte Zobel

JCO Aug 20 2006: 4029–4031. [Full Text] [PDF]

Alveolar Rhabdomyosarcoma Mimicking a Lymphoma at Presentation

Steve C. Tsai, Lisa D. Reale, Neal Flomenberg, Roland Schwarting, and Robert E. Enck

JCO Aug 20 2006: 4031–4032. [Full Text] [PDF]

HISTORY OF ONCOLOGY

Arnoldus Goudsmit, MD, PhD: Chemotherapist, Visionary, Founder of the American Society of Clinical Oncology, 1909-2005

Gretchen M. Krueger, Lori L. Alexander, Deborah A. Whippen, and Charles M. Balch

JCO Aug 20 2006: 4033–4036. [Full Text] [PDF]

CORRESPONDENCE

Influence of Whole-Brain Radiotherapy on Remission of Brain Metastases

Carsten Nieder

JCO Aug 20 2006: 4037. [Full Text] [PDF]

In Reply

Istvan Petak

JCO Aug 20 2006: 4037a–4038. [Full Text] [PDF]

Quality of Life in a Randomized Control Trial? Comments Concerning MA 17.

Pascale This, Anne de la Rochefordière, Anne Bredart, Bernard Asselain, Rollon Poinsot, Sylvie Dolbeault, and Brigitte Sigal-Zafrani

JCO Aug 20 2006: 4038. [Full Text] [PDF]

In Reply

Timothy J. Whelan, Paul E. Goss, James N. Ingle, Donsheng Tu, Lois Shepherd, and Joseph L. Pater

JCO Aug 20 2006: 4038a–4039. [Full Text] [PDF]

On the Origin and Nature of Elevated Levels of Circulating Endothelial Cells After Treatment With a Vascular Disrupting Agent

Yuval Shaked, Francesco Bertolini, Urban Emmenegger, Christina R. Lee, and Robert S. Kerbel

JCO Aug 20 2006: 4040. [Full Text] [PDF]

In Reply

Laurens V. Beerepoot, Els O. Witteveen, and Emile E. Voest

JCO Aug 20 2006: 4040a–4041. [Full Text] [PDF]

Primary Cutaneous B-Cell Lymphoma

Lynn D. Wilson and Benjamin D. Smith

JCO Aug 20 2006: 4041. [Full Text] [PDF]

In Reply

Pier Luigi Zinzani, Pietro Quaglino, Nicola Pimpinelli, Emilio Berti, Gianandrea Baliva, Serena Rupoli, Maurizio Martelli, Mauro Alaibac, Giovanni Borroni, Sergio Chimenti, Renato Alterini, Lapo Alinari, Maria Teresa Fierro, Nazario Cappello, Alessandro Pileri, Davide Soligo, Marco Paulli, Stefano Pileri, Marco Santucci, and Maria Grazia Bernengo

JCO Aug 20 2006: 4041a–4042. [Full Text] [PDF]

Specification on the Definition of Adult-Type Soft Tissue Sarcoma

Andrea Ferrari and Michela Casanova

JCO Aug 20 2006: 4042–4043. [Full Text] [PDF]

In Reply

Sheri L. Spunt and Alberto S. Pappo

JCO Aug 20 2006: 4043–4044. [Full Text] [PDF]

Measuring the Impact of Chemotherapy on Fertility in Women With Breast Cancer

Kutluk Oktay, Ozgur Oktem, Andrea Reh, and Linda Vahdat

JCO Aug 20 2006: 4044–4046. [Full Text] [PDF]

ERRATUM

ERRATUM

JCO Aug 20 2006: 4047. [Full Text] [PDF]

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