EDITORIALS

Cytotoxic Anticancer Agents and Renal Impairment Study: The Challenge Remains

Atiqur Rahman and Robert M. White

JCO Feb 1 2006: 533–536. First published on Jan 3 2006; 10.1200/JCO.2005.03.8299. [Full Text] [PDF]

Consolidation for Ovarian Cancer in Remission

Paul Sabbatini and David R. Spriggs

JCO Feb 1 2006: 537–539. [Full Text] [PDF]

Induction Chemotherapy for Larynx Preservation: Patient Selection or Therapeutic Effect?

David G. Pfister and John A. Ridge

JCO Feb 1 2006: 540–543. First published on Dec 27 2005; 10.1200/JCO.2005.04.1954. [Full Text] [PDF]

Don't Throw Out the Baby With the Bathwater: On Optimizing Cure and Reducing Toxicity in Hodgkin's Lymphoma

Joachim Yahalom

JCO Feb 1 2006: 544–548. [Full Text] [PDF]

Preoperative Chemotherapy and Split-Course Radiation Therapy for Patients With Localized Soft Tissue Sarcomas: Home Run, Base Hit, or Strike Out?

Peter W.T. Pisters

JCO Feb 1 2006: 549–551. [Full Text] [PDF]

ORIGINAL REPORTS
Phase I and Clinical Pharmacology
	Phase I and Pharmacokinetic Study of Pemetrexed Administered Every 3 Weeks to Advanced Cancer Patients With Normal and Impaired Renal Function
	Alain C. Mita, Christopher J. Sweeney, Sharyn D. Baker, Andrew Goetz, Lisa A. Hammond, Amita Patnaik, Anthony W. Tolcher, Miguel Villalona-Calero, Alan Sandler, Tuhin Chaudhuri, Kathleen Molpus, Jane E. Latz, Lorinda Simms, Ajai K. Chaudhary, Robert D. Johnson, Eric K. Rowinsky, and Chris H. Takimoto
	JCO Feb 1 2006: 552–562. First published on Jan 3 2006; 10.1200/JCO.2004.00.9720. [Abstract] [Full Text] [PDF]
	Cefixime Allows Greater Dose Escalation of Oral Irinotecan: A Phase I Study in Pediatric Patients With Refractory Solid Tumors
	Wayne L. Furman, Kristine R. Crews, Catherine Billups, Jianrong Wu, Amar J. Gajjar, Najat C. Daw, Christian C. Patrick, Carlos Rodriguez-Galindo, Clinton F. Stewart, Jeffrey S. Dome, John C. Panetta, Peter J. Houghton, and Victor M. Santana
	JCO Feb 1 2006: 563–570. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Phase III Trial of Intraperitoneal Therapy With Yttrium-90–Labeled HMFG1 Murine Monoclonal Antibody in Patients With Epithelial Ovarian Cancer After a Surgically Defined Complete Remission
	René H. Verheijen, Leon F. Massuger, Benedict B. Benigno, Agamemnon A. Epenetos, Alberto Lopes, John T. Soper, Janica Markowska, Rostislav Vyzula, Tom Jobling, Gordon Stamp, Gregory Spiegel, Dennis Thurston, Theo Falke, Joanna Lambert, and Michael V. Seiden
	JCO Feb 1 2006: 571–578. [Abstract] [Full Text] [PDF]
	Randomized Study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group Comparing Quality of Life in Patients With Ovarian Cancer Treated With Cisplatin/Paclitaxel Versus Carboplatin/Paclitaxel
	Elfriede R. Greimel, Vesna Bjelic-Radisic, Jacobus Pfisterer, Felix Hilpert, Fedor Daghofer, and Andreas du Bois
	JCO Feb 1 2006: 579–586. [Abstract] [Full Text] [PDF]
	Randomized Double-Blind Trial of Estrogen Replacement Therapy Versus Placebo in Stage I or II Endometrial Cancer: A Gynecologic Oncology Group Study
	Richard R. Barakat, Brian N. Bundy, Nick M. Spirtos, Jeffrey Bell, and Robert S. Mannel
	JCO Feb 1 2006: 587–592. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Single-Cycle Induction Chemotherapy Selects Patients With Advanced Laryngeal Cancer for Combined Chemoradiation: A New Treatment Paradigm
	Susan Urba, Gregory Wolf, Avraham Eisbruch, Francis Worden, Julia Lee, Carol Bradford, Theodoros Teknos, Douglas Chepeha, Mark Prince, Norman Hogikyan, and Jeremy Taylor
	JCO Feb 1 2006: 593–598. First published on Dec 27 2005; 10.1200/JCO.2005.01.2047. [Abstract] [Full Text] [PDF]
	[18F]Fluorodeoxyglucose Positron Emission Tomography Is More Sensitive Than Skeletal Scintigraphy for Detecting Bone Metastasis in Endemic Nasopharyngeal Carcinoma at Initial Staging
	Feng-Yuan Liu, Joseph T. Chang, Hung-Ming Wang, Chun-Ta Liao, Chung-Jan Kang, Shu-Kung Ng, Sheng-Chieh Chan, and Tzu-Chen Yen
	JCO Feb 1 2006: 599–604. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Combined-Modality Therapy Versus Radiotherapy Alone for Treatment of Early-Stage Hodgkin's Disease: Cure Balanced Against Complications
	Bridget F. Koontz, John P. Kirkpatrick, Robert W. Clough, Robert G. Prosnitz, Jon P. Gockerman, Joseph O. Moore, and Leonard R. Prosnitz
	JCO Feb 1 2006: 605–611. [Abstract] [Full Text] [PDF]
	Extranodal Natural Killer T-Cell Lymphoma, Nasal-Type: A Prognostic Model From a Retrospective Multicenter Study
	Jeeyun Lee, Cheolwon Suh, Yeon Hee Park, Young H. Ko, Soo Mee Bang, Jae Hoon Lee, Dae Ho Lee, Jooryung Huh, Sung Yong Oh, Hyuk-Chan Kwon, Hyo Jin Kim, Soon Il Lee, Jung Han Kim, Jinny Park, Seok Joong Oh, Kihyun Kim, Chulwon Jung, Keunchil Park, and Won Seog Kim
	JCO Feb 1 2006: 612–618. First published on Dec 27 2005; 10.1200/JCO.2005.04.1384. [Abstract] [Full Text] [PDF]

Sarcomas
	Phase II Study of Neoadjuvant Chemotherapy and Radiation Therapy in the Management of High-Risk, High-Grade, Soft Tissue Sarcomas of the Extremities and Body Wall: Radiation Therapy Oncology Group Trial 9514
	William G. Kraybill, Jonathon Harris, Ira J. Spiro, David S. Ettinger, Thomas F. DeLaney, Ronald H. Blum, David R. Lucas, David C. Harmon, G. Douglas Letson, and Burton Eisenberg
	JCO Feb 1 2006: 619–625. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Results of the National Initiative for Cancer Care Quality: How Can We Improve the Quality of Cancer Care in the United States?
	Jennifer L. Malin, Eric C. Schneider, Arnold M. Epstein, John Adams, Ezekiel J. Emanuel, and Katherine L. Kahn
	JCO Feb 1 2006: 626–634. First published on Jan 9 2006; 10.1200/JCO.2005.03.3365. [Abstract] [Full Text] [PDF] [Publisher's Note]
	Impacting Quality of Life for Patients With Advanced Cancer With a Structured Multidisciplinary Intervention: A Randomized Controlled Trial
	Teresa A. Rummans, Matthew M. Clark, Jeff A. Sloan, Marlene H. Frost, John Michael Bostwick, Pamela J. Atherton, Mary E. Johnson, Gail Gamble, Jarrett Richardson, Paul Brown, James Martensen, Janis Miller, Katherine Piderman, Mashele Huschka, Jean Girardi, and Jean Hanson
	JCO Feb 1 2006: 635–642. [Abstract] [Full Text] [PDF]

Bone Marrow Transplantation
	Outcome of Critically Ill Allogeneic Hematopoietic Stem-Cell Transplantation Recipients: A Reappraisal of Indications for Organ Failure Supports
	Frédéric Pène, Cécile Aubron, Elie Azoulay, François Blot, Guillaume Thiéry, Bruno Raynard, Benoît Schlemmer, Gérard Nitenberg, Agnès Buzyn, Philippe Arnaud, Gérard Socié, and Jean-Paul Mira
	JCO Feb 1 2006: 643–649. First published on Dec 27 2005; 10.1200/JCO.2005.03.9073. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Randomized Phase II Study of Neoadjuvant Combined-Modality Chemoradiation for Distal Rectal Cancer: Radiation Therapy Oncology Group Trial 0012
	Mohammed Mohiuddin, Kathryn Winter, Edith Mitchell, Nader Hanna, Albert Yuen, Charles Nichols, Robert Shane, Cherie Hayostek, and Christopher Willett
	JCO Feb 1 2006: 650–655. [Abstract] [Full Text] [PDF]
	Increased Toxicity With Gefitinib, Capecitabine, and Radiation Therapy in Pancreatic and Rectal Cancer: Phase I Trial Results
	Brian G. Czito, Christopher G. Willett, Johanna C. Bendell, Michael A. Morse, Douglas S. Tyler, Nishan H. Fernando, Christopher R. Mantyh, Gerard C. Blobe, Wanda Honeycutt, Daohai Yu, Bryan M. Clary, Theodore N. Pappas, Kirk A. Ludwig, and Herbert I. Hurwitz
	JCO Feb 1 2006: 656–662. [Abstract] [Full Text] [PDF]
	Multicenter Phase II Trial of S-1 Plus Cisplatin in Patients With Untreated Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
	Jaffer A. Ajani, Fa-Chyi Lee, Deepti A. Singh, Daniel G. Haller, Heinz-Josef Lenz, Al B. Benson, III, Ronald Yanagihara, Alexandria T. Phan, James C. Yao, and Dirk Strumberg
	JCO Feb 1 2006: 663–667. [Abstract] [Full Text] [PDF]
	Neoadjuvant Capecitabine and Oxaliplatin Followed by Synchronous Chemoradiation and Total Mesorectal Excision in Magnetic Resonance Imaging–Defined Poor-Risk Rectal Cancer
	Ian Chau, Gina Brown, David Cunningham, Diana Tait, Andrew Wotherspoon, Andrew R. Norman, Niall Tebbutt, Mark Hill, Paul J. Ross, Alison Massey, and Jacqueline Oates
	JCO Feb 1 2006: 668–674. [Abstract] [Full Text] [PDF]

Breast Cancer
	Tamoxifen Treatment After Adjuvant Chemotherapy Has Opposite Effects on Bone Mineral Density in Premenopausal Patients Depending on Menstrual Status
	Leena Vehmanen, Inkeri Elomaa, Carl Blomqvist, and Tiina Saarto
	JCO Feb 1 2006: 675–680. [Abstract] [Full Text] [PDF]

Lung Cancer
	Adding Gemcitabine to Paclitaxel/Carboplatin Combination Increases Survival in Advanced Non–Small-Cell Lung Cancer: Results of a Phase II-III Study
	Adriano Paccagnella, Francesco Oniga, Alessandra Bearz, Adolfo Favaretto, Maurizia Clerici, Fausto Barbieri, Alberto Riccardi, Antonio Chella, Umberto Tirelli, Giovanni Ceresoli, Salvatore Tumolo, Ruggero Ridolfi, Rita Biason, Maria Ornella Nicoletto, Paolo Belloni, Fabrizio Veglia, and Maria Grazia Ghi
	JCO Feb 1 2006: 681–687. [Abstract] [Full Text] [PDF]
	Randomized Phase II Trial Comparing Nitroglycerin Plus Vinorelbine and Cisplatin With Vinorelbine and Cisplatin Alone in Previously Untreated Stage IIIB/IV Non–Small-Cell Lung Cancer
	Hiroyasu Yasuda, Mutsuo Yamaya, Katsutoshi Nakayama, Takahiko Sasaki, Satoru Ebihara, Akio Kanda, Masanori Asada, Daisuke Inoue, Tomoko Suzuki, Tatsuma Okazaki, Hidenori Takahashi, Motoki Yoshida, Tomohiro Kaneta, Kota Ishizawa, Shinsuke Yamanda, Naoki Tomita, Miyako Yamasaki, Akiko Kikuchi, Hiroshi Kubo, and Hidetada Sasaki
	JCO Feb 1 2006: 688–694. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Prognostic Value of International Neuroblastoma Pathology Classification in Localized Resectable Peripheral Neuroblastic Tumors: A Histopathologic Study of Localized Neuroblastoma European Study Group 94.01 Trial and Protocol
	Samuel Navarro, Gabriele Amann, Klaus Beiske, Catherine J. Cullinane, Emanuele S.G. d'Amore, Claudio Gambini, Véronique Mosseri, Bruno De Bernardi, Jean Michon, and Michel Peuchmaur
	JCO Feb 1 2006: 695–699. [Abstract] [Full Text] [PDF]

Genetic Testing for Cancer
	Sharing BRCA1/2 Test Results With First-Degree Relatives: Factors Predicting Who Women Tell
	Andrea Farkas Patenaude, Michel Dorval, Lisa S. DiGianni, Katherine A. Schneider, Anu Chittenden, and Judy E. Garber
	JCO Feb 1 2006: 700–706. [Abstract] [Full Text] [PDF]
	Optimal Selection of Individuals for BRCA Mutation Testing: A Comparison of Available Methods
	Paul A. James, Rebecca Doherty, Marion Harris, Bickol N. Mukesh, Alvin Milner, Mary-Anne Young, and Clare Scott
	JCO Feb 1 2006: 707–715. [Abstract] [Full Text] [PDF]

ART OF ONCOLOGY

Discussing Bad News in the Outpatient Oncology Clinic: Rethinking Current Communication Guidelines

Susan Eggly, Louis Penner, Terrance L. Albrecht, Rebecca J.W. Cline, Tanina Foster, Michael Naughton, Amy Peterson, and John C. Ruckdeschel

JCO Feb 1 2006: 716–719. [Full Text] [PDF]

CORRESPONDENCE
	Patient Consent in the Era of De-Identified Research Databases
	James R. Anderson and Toby L. Schonfeld
	JCO Feb 1 2006: 720–721. [Full Text] [PDF]
	Molecular Forecasting of Breast Cancer: Time to Move Forward With Clinical Testing
	Sherene Loi, Christos Sotiriou, Marc Buyse, Emiel Rutgers, Laura Van't Veer, Martine Piccart, and Fatima Cardoso
	JCO Feb 1 2006: 721–722. [Full Text] [PDF]
	In Reply:
	James D. Brenton, Ahmed Ashour Ahmed, and Carlos Caldas
	JCO Feb 1 2006: 722–723. [Full Text] [PDF]
	First Case of an AIDS Patient With Systemic Mast Cell Disease Associated With Eosinophilia FIP1-Positive Treated With Imatinib Mesylate Therapy
	Merante Serena, Chichino Guido, Boveri Emanuela, Gottardi Enrico, Soverini Simona, Cilloni Daniela, and Martinelli Giovanni
	JCO Feb 1 2006: e6–7. [Full Text] [PDF]

ERRATA

ERRATUM

JCO Feb 1 2006: 724. [Full Text] [PDF]

ERRATUM

JCO Feb 1 2006: 724-a. [Full Text] [PDF]

ERRATUM

JCO Feb 1 2006: 724-b. [Full Text] [PDF]

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