EDITORIALS

More Support for the Judicious Use of High-Dose Interleukin-2 in Patients With Advanced Melanoma

David F. McDermott and Michael B. Atkins

JCO Sep 1 2007: 3791–3793. [Full Text] [PDF]

The Heart of the Matter

Chia C. Portera and Sandra M. Swain

JCO Sep 1 2007: 3794–3796. First published on Jul 30 2007; 10.1200/JCO.2007.11.9537. [Full Text] [PDF]

Aromatase Inhibitors and Arthralgias: A New Frontier in Symptom Management for Breast Cancer Survivors

Harold J. Burstein and Eric P. Winer

JCO Sep 1 2007: 3797–3799. [Full Text] [PDF]

Cancer Survivorship Research and Guidelines: Maybe the Cart Should Be Beside the Horse

Craig C. Earle

JCO Sep 1 2007: 3800–3801. First published on Jul 23 2007; 10.1200/JCO.2007.12.2325. [Full Text] [PDF]

ORIGINAL REPORTS
Melanoma
	Durable Complete Responses With High-Dose Bolus Interleukin-2 in Patients With Metastatic Melanoma Who Have Experienced Progression After Biochemotherapy
	Ahmad A. Tarhini, John M. Kirkwood, William E. Gooding, Chao Cai, and Sanjiv S. Agarwala
	JCO Sep 1 2007: 3802–3807. [Abstract] [Full Text] [PDF]

Breast Cancer
	Congestive Heart Failure in Older Women Treated With Adjuvant Anthracycline Chemotherapy for Breast Cancer
	Mary C. Pinder, Zhigang Duan, James S. Goodwin, Gabriel N. Hortobagyi, and Sharon H. Giordano
	JCO Sep 1 2007: 3808–3815. First published on Jul 30 2007; 10.1200/JCO.2006.10.4976. [Abstract] [Full Text] [PDF]
	A Phase II Placebo-Controlled Trial of Neoadjuvant Anastrozole Alone or With Gefitinib in Early Breast Cancer
	Ian E. Smith, Geraldine Walsh, Anthony Skene, Antonio Llombart, José Ignacio Mayordomo, Simone Detre, Janine Salter, Emma Clark, Patrick Magill, and Mitch Dowsett
	JCO Sep 1 2007: 3816–3822. First published on Aug 6 2007; 10.1200/JCO.2006.09.6578. [Abstract] [Full Text] [PDF]
	What Is the Psychological Impact of Mammographic Screening on Younger Women With a Family History of Breast Cancer? Findings From a Prospective Cohort Study by the PIMMS Management Group
	Sally Tyndel, Joan Austoker, Bethan J. Henderson, Kate Brain, Clare Bankhead, Alison Clements, and Eila K. Watson
	JCO Sep 1 2007: 3823–3830. [Abstract] [Full Text] [PDF]
	Oral Contraceptives and Breast Cancer Risk in the International BRCA1/2 Carrier Cohort Study: A Report From EMBRACE, GENEPSO, GEO-HEBON, and the IBCCS Collaborating Group
	Richard M. Brohet, David E. Goldgar, Douglas F. Easton, Antonis C. Antoniou, Nadine Andrieu, Jenny Chang-Claude, Susan Peock, Rosalind A. Eeles, Margaret Cook, Carol Chu, Catherine Noguès, Christine Lasset, Pascaline Berthet, Hanne Meijers-Heijboer, Anne-Marie Gerdes, Håkan Olsson, Trinidad Caldes, Flora E. van Leeuwen, and Matti A. Rookus
	JCO Sep 1 2007: 3831–3836. First published on Jul 16 2007; 10.1200/JCO.2007.11.1179. [Abstract] [Full Text] [PDF]
	Clinical Implications of CYP2D6 Genotypes Predictive of Tamoxifen Pharmacokinetics in Metastatic Breast Cancer
	Hyeong-Seok Lim, Han Ju Lee, Keun Seok Lee, Eun Sook Lee, In-Jin Jang, and Jungsil Ro
	JCO Sep 1 2007: 3837–3845. [Abstract] [Full Text] [PDF]
	Prognostic and Predictive Value of Centrally Reviewed Expression of Estrogen and Progesterone Receptors in a Randomized Trial Comparing Letrozole and Tamoxifen Adjuvant Therapy for Postmenopausal Early Breast Cancer: BIG 1-98
	Giuseppe Viale, Meredith M. Regan, Eugenio Maiorano, Mauro G. Mastropasqua, Patrizia Dell'Orto, Birgitte Bruun Rasmussen, Johnny Raffoul, Patrick Neven, Zsolt Orosz, Stephen Braye, Christian Öhlschlegel, Beat Thürlimann, Richard D. Gelber, Monica Castiglione-Gertsch, Karen N. Price, Aron Goldhirsch, Barry A. Gusterson, and Alan S. Coates
	JCO Sep 1 2007: 3846–3852. First published on Aug 6 2007; 10.1200/JCO.2007.11.9453. [Abstract] [Full Text] [PDF]
	Capecitabine and Trastuzumab in Heavily Pretreated Metastatic Breast Cancer
	Rupert Bartsch, Catharina Wenzel, Gabriela Altorjai, Ursula Pluschnig, Margaretha Rudas, Robert M. Mader, Michael Gnant, Christoph C. Zielinski, and Guenther G. Steger
	JCO Sep 1 2007: 3853–3858. First published on Aug 6 2007; 10.1200/JCO.2007.11.9776. [Abstract] [Full Text] [PDF]

Treatment-Related Complications
	Trastuzumab-Associated Cardiac Adverse Effects in the Herceptin Adjuvant Trial
	Thomas M. Suter, Marion Procter, Dirk J. van Veldhuisen, Michael Muscholl, Jonas Bergh, Chiara Carlomagno, Timothy Perren, Rodolfo Passalacqua, Claudia Bighin, Jan G.M. Klijn, Fail T. Ageev, Erika Hitre, Juergen Groetz, Hiroji Iwata, Malgorzata Knap, Michael Gnant, Susanne Muehlbauer, Alison Spence, Richard D. Gelber, and Martine J. Piccart-Gebhart
	JCO Sep 1 2007: 3859–3865. First published on Jul 23 2007; 10.1200/JCO.2006.09.1611. [Abstract] [Full Text] [PDF] [Polish PDF]
	Brain Structure and Function Differences in Monozygotic Twins: Possible Effects of Breast Cancer Chemotherapy
	Robert J. Ferguson, Brenna C. McDonald, Andrew J. Saykin, and Tim A. Ahles
	JCO Sep 1 2007: 3866–3870. [Abstract] [Full Text] [PDF]
	Acute Myeloid Leukemia After Adjuvant Breast Cancer Therapy in Older Women: Understanding Risk
	Debra A. Patt, Zhigang Duan, Shenying Fang, Gabriel N. Hortobagyi, and Sharon H. Giordano
	JCO Sep 1 2007: 3871–3876. First published on Jul 30 2007; 10.1200/JCO.2007.12.0832. [Abstract] [Full Text] [PDF]
	Prevalence of Joint Symptoms in Postmenopausal Women Taking Aromatase Inhibitors for Early-Stage Breast Cancer
	Katherine D. Crew, Heather Greenlee, Jillian Capodice, George Raptis, Lois Brafman, Deborah Fuentes, Alex Sierra, and Dawn L. Hershman
	JCO Sep 1 2007: 3877–3883. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Phase I Study of Decitabine Alone or in Combination With Valproic Acid in Acute Myeloid Leukemia
	William Blum, Rebecca B. Klisovic, Bjoern Hackanson, Zhongfa Liu, Shujun Liu, Hollie Devine, Tamara Vukosavljevic, Lenguyen Huynh, Gerard Lozanski, Cheryl Kefauver, Christoph Plass, Steven M. Devine, Nyla A. Heerema, Anthony Murgo, Kenneth K. Chan, Michael R. Grever, John C. Byrd, and Guido Marcucci
	JCO Sep 1 2007: 3884–3891. First published on Aug 6 2007; 10.1200/JCO.2006.09.4169. [Abstract] [Full Text] [PDF]
	Randomized Phase III Study of Pegylated Liposomal Doxorubicin Plus Bortezomib Compared With Bortezomib Alone in Relapsed or Refractory Multiple Myeloma: Combination Therapy Improves Time to Progression
	Robert Z. Orlowski, Arnon Nagler, Pieter Sonneveld, Joan Bladé, Roman Hajek, Andrew Spencer, Jesús San Miguel, Tadeusz Robak, Anna Dmoszynska, Noemi Horvath, Ivan Spicka, Heather J. Sutherland, Alexander N. Suvorov, Sen H. Zhuang, Trilok Parekh, Liang Xiu, Zhilong Yuan, Wayne Rackoff, and Jean-Luc Harousseau
	JCO Sep 1 2007: 3892–3901. First published on Aug 6 2007; 10.1200/JCO.2006.10.5460. [Abstract] [Full Text] [PDF] [Russian PDF]
	Impact of Positive Positron Emission Tomography on Prediction of Freedom From Progression After Stanford V Chemotherapy in Hodgkin's Disease
	Ranjana Advani, Lauren Maeda, Philip Lavori, Andrew Quon, Richard Hoppe, Sheila Breslin, Saul A. Rosenberg, and Sandra J. Horning
	JCO Sep 1 2007: 3902–3907. First published on Jul 30 2007; 10.1200/JCO.2007.11.9867. [Abstract] [Full Text] [PDF]
	Pleural Effusion in Patients With Chronic Myelogenous Leukemia Treated With Dasatinib After Imatinib Failure
	Alfonso Quintás-Cardama, Hagop Kantarjian, Susan O'Brien, Gautham Borthakur, John Bruzzi, Reginald Munden, and Jorge Cortes
	JCO Sep 1 2007: 3908–3914. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Prevalence, Clinical Pattern, and Outcome of CNS Involvement in Childhood and Adolescent Non-Hodgkin's Lymphoma Differ by Non-Hodgkin's Lymphoma Subtype: A Berlin-Frankfurt-Münster Group Report
	Janina Salzburg, Birgit Burkhardt, Martin Zimmermann, Olga Wachowski, Wilhelm Woessmann, Ilske Oschlies, Wolfram Klapper, Hans-Heinrich Wacker, Wolf-Dieter Ludwig, Felix Niggli, Georg Mann, Helmut Gadner, Hansjoerg Riehm, Martin Schrappe, and Alfred Reiter
	JCO Sep 1 2007: 3915–3922. [Abstract] [Full Text] [PDF]

Epidemiology
	Shifting Breast Cancer Trends in the United States
	William F. Anderson, Anne S. Reiner, Rayna K. Matsuno, and Ruth M. Pfeiffer
	JCO Sep 1 2007: 3923–3929. First published on Aug 6 2007; 10.1200/JCO.2007.11.6079. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Nuclear Factor-kB Tumor Expression Predicts Response and Survival in Irinotecan-Refractory Metastatic Colorectal Cancer Treated With Cetuximab-Irinotecan Therapy
	Mario Scartozzi, Italo Bearzi, Chiara Pierantoni, Alessandra Mandolesi, Fotios Loupakis, Alberto Zaniboni, Vincenzo Catalano, Antonello Quadri, Fausto Zorzi, Rossana Berardi, Tommasina Biscotti, Roberto Labianca, Alfredo Falcone, and Stefano Cascinu
	JCO Sep 1 2007: 3930–3935. [Abstract] [Full Text] [PDF]

Thoracic Oncology
	Multicenter, Randomized, Phase II Trial of CI-1033, an Irreversible Pan-ERBB Inhibitor, for Previously Treated Advanced Non–Small-Cell Lung Cancer
	Pasi A. Jänne, Joachim von Pawel, Roger B. Cohen, Lucio Crino, Charles A. Butts, Steven S. Olson, Irene A. Eiseman, Alberto A. Chiappori, Beow Y. Yeap, Peter F. Lenehan, Kathy Dasse, Meredith Sheeran, and Philip D. Bonomi
	JCO Sep 1 2007: 3936–3944. [Abstract] [Full Text] [PDF]
	Phase III Double-Blind, Placebo-Controlled Study of Thalidomide in Extensive-Disease Small-Cell Lung Cancer After Response to Chemotherapy: An Intergroup Study FNCLCC cleo04–IFCT 00-01
	Jean Louis Pujol, Jean Luc Breton, Radj Gervais, Marie-Laure Tanguy, Elisabeth Quoix, Philippe David, Henri Janicot, Virginie Westeel, Sabine Gameroff, Jean Genève, and Dominique Maraninchi
	JCO Sep 1 2007: 3945–3951. [Abstract] [Full Text] [PDF]
	Epidermal Growth Factor Receptor Mutation Status and Adjuvant Chemotherapy With Uracil-Tegafur for Adenocarcinoma of the Lung
	Hiroshi Suehisa, Shinichi Toyooka, Katsuyuki Hotta, Akiko Uchida, Junichi Soh, Yoshiro Fujiwara, Keitaro Matsuo, Mamoru Ouchida, Minoru Takata, Katsuyuki Kiura, and Hiroshi Date
	JCO Sep 1 2007: 3952–3957. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Phase I/II Trial of Temsirolimus Combined With Interferon Alfa for Advanced Renal Cell Carcinoma
	Robert J. Motzer, Gary R. Hudes, Brendan D. Curti, David F. McDermott, Bernard J. Escudier, Sylvie Negrier, Brigitte Duclos, Laurence Moore, Timothy O'Toole, Joseph P. Boni, and Janice P. Dutcher
	JCO Sep 1 2007: 3958–3964. [Abstract] [Full Text] [PDF]
	Prostate-Specific Antigen and Pain Surrogacy Analysis in Metastatic Hormone-Refractory Prostate Cancer
	Andrew J. Armstrong, Elizabeth Garrett-Mayer, Yi-Chun Ou Yang, Michael A. Carducci, Ian Tannock, Ronald de Wit, and Mario Eisenberger
	JCO Sep 1 2007: 3965–3970. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Phase II Trial of Chemoradiation for Organ Preservation in Resectable Stage III or IV Squamous Cell Carcinomas of the Larynx or Oropharynx: Results of Eastern Cooperative Oncology Group Study E2399
	Anthony J. Cmelak, Sigui Li, Meredith A. Goldwasser, Barbara Murphy, Michael Cannon, Harlan Pinto, David I. Rosenthal, Maura Gillison, and Arlene A. Forastiere
	JCO Sep 1 2007: 3971–3977. [Abstract] [Full Text] [PDF] [Russian PDF]
	Phase II Study of Lapatinib in Recurrent or Metastatic Epidermal Growth Factor Receptor and/or erbB2 Expressing Adenoid Cystic Carcinoma and Non–Adenoid Cystic Carcinoma Malignant Tumors of the Salivary Glands
	Mark Agulnik, Ezra W.E. Cohen, Roger B. Cohen, Eric X. Chen, Everett E. Vokes, Sebastien J. Hotte, Eric Winquist, Scott Laurie, D. Neil Hayes, Janet E. Dancey, Shirley Brown, Gregory R. Pond, Ian Lorimer, Manijeh Daneshmand, James Ho, Ming-Sound Tsao, and Lillian L. Siu
	JCO Sep 1 2007: 3978–3984. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Primary Fallopian Tube Malignancies in BRCA-Positive Women Undergoing Surgery for Ovarian Cancer Risk Reduction
	Michael J. Callahan, Christopher P. Crum, Fabiola Medeiros, David W. Kindelberger, Julia A. Elvin, Judy E. Garber, Colleen M. Feltmate, Ross S. Berkowitz, and Michael G. Muto
	JCO Sep 1 2007: 3985–3990. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLE
	American Society of Clinical Oncology Clinical Evidence Review on the Ongoing Care of Adult Cancer Survivors: Cardiac and Pulmonary Late Effects
	Joseph R. Carver, Charles L. Shapiro, Andrea Ng, Linda Jacobs, Cindy Schwartz, Katherine S. Virgo, Karen L. Hagerty, Mark R. Somerfield, David J. Vaughn for the ASCO Cancer Survivorship Expert Panel
	JCO Sep 1 2007: 3991–4008. First published on Jun 18 2007; 10.1200/JCO.2007.10.9777. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Pleural Metastases From Renal Cell Carcinoma 16 Years After Resection

Mitsuhiro Kamiyoshihara, Takashi Ibe, Atsushi Takise, Hideaki Itou, and Izumi Takeyoshi

JCO Sep 1 2007: 4009–4011. [Full Text] [PDF]

Presentation of Childhood Acute Myeloid Leukemia With Erythema Nodosum

Milena La Spina and Giovanna Russo

JCO Sep 1 2007: 4011–4012. [Full Text] [PDF]

Retrorectal Cystic Hamartoma As Benign Cause of CA 19-9 Elevation

Jesus Garcia-Donas, Nuria Rodriguez, Carlos Jara, Miguel Urioste, Manuel Nevado, Marta Cañamero, Victoria Cuartero, Jose Albillos, Daniel Vega, and Antonio Quintans

JCO Sep 1 2007: 4012–4014. [Full Text] [PDF]

ART OF ONCOLOGY

When Two Worlds Collide

John A. Heath, Katherine Moore, Merle Spriggs, and Keith D. Waters

JCO Sep 1 2007: 4015–4017. [Full Text] [PDF]

Special Treatment: A Commentary on "When Two Worlds Collide"

Paulette Mehta

JCO Sep 1 2007: 4018–4019. [Full Text] [PDF]

CORRESPONDENCE
	Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer
	Kirsten Vang Nielsen, Jan T. Jørgensen, Andreas Schønau, and Anne Øster
	JCO Sep 1 2007: 4020. [Full Text] [PDF]
	Human Epidermal Growth Factor Receptor 2 Testing Recommendation
	Adekunle Raji
	JCO Sep 1 2007: 4020-a–4021. [Full Text] [PDF]
	In Reply
	Antonio C. Wolff, M. Elizabeth H. Hammond, Jared N. Schwartz, Daniel F. Hayes On behalf of the ASCO/CAP Panel on HER-2 Testing in Breast Cancer
	JCO Sep 1 2007: 4021–4023. [Full Text] [PDF]
	Avoiding Bias in the Prospective Evaluation of Patients With Brain Metastases
	Dirk Vordermark
	JCO Sep 1 2007: 4023. [Full Text] [PDF]
	In Reply
	Jing Li, Soren M. Bentzen, Minesh P. Mehta, and Markus Renschler
	JCO Sep 1 2007: 4024–4025. [Full Text] [PDF]
	Is Surgery Still Part of Local Therapy in Patients With Locally Advanced Esophageal Carcinoma?
	Thomas Ruhstaller, Beat Thuerlimann, Dieter Koeberle, and Roger von Moos
	JCO Sep 1 2007: 4025–4026. [Full Text] [PDF]
	In Reply
	Laurent Bedenne and Franck Bonnetain
	JCO Sep 1 2007: 4026–4027. [Full Text] [PDF]
	Reliable Evidence of Safety and Efficacy of Elderly Patients in Randomized Clinical Trials Still Needed
	Sheila M. Crean, Matthew W. Reynolds, and Christin A. Dematto
	JCO Sep 1 2007: 4027–4028. [Full Text] [PDF]
	In Reply
	Ambuj Kumar and Benjamin Djulbegovic
	JCO Sep 1 2007: 4028. [Full Text] [PDF]
	Use of Calcium and Magnesium Salts to Reduce Oxaliplatin-Related Neurotoxicity
	Howard S. Hochster, Axel Grothey, and Barrett H. Childs
	JCO Sep 1 2007: 4028-a–4029. First published on Jul 30 2007; 10.1200/JCO.2007.13.5251. [Full Text] [PDF]
	A Positive Step Forward, but More Needed to Maximize Cost Benefits of New-Generation Cancer Therapies
	Ian E. Haines
	JCO Sep 1 2007: e31–32. [Full Text] [PDF]

ERRATUM

ERRATUM

JCO Sep 1 2007: 4030. [Full Text] [PDF]

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