CELEBRATING 25 YEARS OF JCO

Commentary

Chemotherapy for Advanced Prostate Cancer: 25 Years Later

Christopher J. Logothetis and Randall Millikan

JCO May 20 2008: 2423–2424. [Full Text] [PDF] [From JCO 1983]

EDITORIALS

Introducing New Treatments and Technologies Into the Clinic

JCO May 20 2008: 2425. First published on Apr 28 2008; 10.1200/JCO.2008.17.4136. [Full Text] [PDF]

Molecular Selection of Patients for First-Line Treatment of Advanced Non–Small-Cell Lung Cancer With Epidermal Growth Factor Inhibitors: Not Quite Ready for Prime Time

Frances A. Shepherd

JCO May 20 2008: 2426–2427. First published on May 5 2008; 10.1200/JCO.2007.15.4286. [Full Text] [PDF]

Does Gefitinib Shorten Lung Cancer Survival? Chaos Redux

Vicki L. Keedy, Carlos L. Arteaga, and David H. Johnson

JCO May 20 2008: 2428–2430. First published on Mar 31 2008; 10.1200/JCO.2008.16.0374. [Full Text] [PDF]

Losing Sleep Over Cancer

David Spiegel

JCO May 20 2008: 2431–2432. [Full Text] [PDF]

Problems and Solutions in the Evaluation of Hormone Receptors in Breast Cancer

D. Craig Allred

JCO May 20 2008: 2433–2435. [Full Text] [PDF]

COMMENTS AND CONTROVERSIES

Protons and Parachutes

Joel E. Tepper

JCO May 20 2008: 2436–2437. First published on Apr 28 2008; 10.1200/JCO.2008.17.1165. [Full Text] [PDF]

Should Randomized Clinical Trials Be Required for Proton Radiotherapy? An Alternative View

Eli Glatstein, John Glick, Larry Kaiser, and Stephen M. Hahn

JCO May 20 2008: 2438–2439. First published on Apr 28 2008; 10.1200/JCO.2008.17.1843. [Full Text] [PDF]

Clinical Trial Investigator Status: You Need to Earn It

Nicholas J. Petrelli, Stephen Grubbs, and Kandie Price

JCO May 20 2008: 2440–2441. [Full Text] [PDF]

ORIGINAL REPORTS
Thoracic Oncology
	First-Line Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer Harboring Somatic EGFR Mutations
	Lecia V. Sequist, Renato G. Martins, David Spigel, Steven M. Grunberg, Alexander Spira, Pasi A. Jänne, Victoria A. Joshi, David McCollum, Tracey L. Evans, Alona Muzikansky, Georgiana L. Kuhlmann, Moon Han, Jonathan S. Goldberg, Jeffrey Settleman, A. John Iafrate, Jeffrey A. Engelman, Daniel A. Haber, Bruce E. Johnson, and Thomas J. Lynch
	JCO May 20 2008: 2442–2449. First published on May 5 2008; 10.1200/JCO.2007.14.8494. [Abstract] [Full Text] [PDF] [Publisher's Note]
	Phase III Trial of Maintenance Gefitinib or Placebo After Concurrent Chemoradiotherapy and Docetaxel Consolidation in Inoperable Stage III Non–Small-Cell Lung Cancer: SWOG S0023
	Karen Kelly, Kari Chansky, Laurie E. Gaspar, Kathy S. Albain, James Jett, Yee C. Ung, Derick H.M. Lau, John J. Crowley, and David R. Gandara
	JCO May 20 2008: 2450–2456. First published on Mar 31 2008; 10.1200/JCO.2007.14.4824. [Abstract] [Full Text] [PDF]
	Randomized Phase II Trial of Induction Chemotherapy Followed by Concurrent Chemotherapy and Dose-Escalated Thoracic Conformal Radiotherapy (74 Gy) in Stage III Non–Small-Cell Lung Cancer: CALGB 30105
	Mark A. Socinski, A. William Blackstock, Jeffrey A. Bogart, Xiaofei Wang, Michael Munley, Julian Rosenman, Lin Gu, Gregory A. Masters, Peter Ungaro, Arthur Sleeper, Mark Green, Antonius A. Miller, and Everett E. Vokes
	JCO May 20 2008: 2457–2463. [Abstract] [Full Text] [PDF]

Palliative Care
	Sleep/Wake Patterns of Individuals With Advanced Cancer Measured by Ambulatory Polysomnography
	Kathy P. Parker, Donald L. Bliwise, Maria Ribeiro, Sanjay R. Jain, Catherine I. Vena, Mary Kay Kohles-Baker, Andre Rogatko, Zhiheng Xu, and Wayne B. Harris
	JCO May 20 2008: 2464–2472. [Abstract] [Full Text] [PDF]

Breast Cancer
	Estrogen- and Progesterone-Receptor Status in ECOG 2197: Comparison of Immunohistochemistry by Local and Central Laboratories and Quantitative Reverse Transcription Polymerase Chain Reaction by Central Laboratory
	Sunil S. Badve, Frederick L. Baehner, Robert P. Gray, Barrett H. Childs, Tara Maddala, Mei-Lan Liu, Steve C. Rowley, Steven Shak, Edith D. Perez, Lawrence J. Shulman, Silvana Martino, Nancy E. Davidson, George W. Sledge, Lori J. Goldstein, and Joseph A. Sparano
	JCO May 20 2008: 2473–2481. [Abstract] [Full Text] [PDF]
	Mammography Before Diagnosis Among Women Age 80 Years and Older With Breast Cancer
	Brian D. Badgwell, Sharon H. Giordano, Zhigang Z. Duan, Shenying Fang, Isabelle Bedrosian, Henry M. Kuerer, S. Eva Singletary, Kelly K. Hunt, Gabriel N. Hortobagyi, and Gildy Babiera
	JCO May 20 2008: 2482–2488. First published on Apr 21 2008; 10.1200/JCO.2007.12.8058. [Abstract] [Full Text] [PDF]

Head and Neck Cancer
	Phase II Study of Palifermin and Concurrent Chemoradiation in Head and Neck Squamous Cell Carcinoma
	David M. Brizel, Barbara A. Murphy, David I. Rosenthal, Kishan J. Pandya, Stefan Glück, Herbert E. Brizel, Ruby F. Meredith, Dietmar Berger, Mon-Gy Chen, and William Mendenhall
	JCO May 20 2008: 2489–2496. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	Ten-Year Follow-Up of Radiation Therapy Oncology Group Protocol 92-02: A Phase III Trial of the Duration of Elective Androgen Deprivation in Locally Advanced Prostate Cancer
	Eric M. Horwitz, Kyounghwa Bae, Gerald E. Hanks, Arthur Porter, David J. Grignon, Harmar D. Brereton, Varagur Venkatesan, Colleen A. Lawton, Seth A. Rosenthal, Howard M. Sandler, and William U. Shipley
	JCO May 20 2008: 2497–2504. First published on Apr 14 2008; 10.1200/JCO.2007.14.9021. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Factors Affecting Response and Survival in Patients With Myelodysplasia Treated With Immunosuppressive Therapy
	Elaine M. Sloand, Colin O. Wu, Peter Greenberg, Neal Young, and John Barrett
	JCO May 20 2008: 2505–2511. First published on Apr 14 2008; 10.1200/JCO.2007.11.9214. [Abstract] [Full Text] [PDF]
	Intensive Chemotherapy Followed by Hematopoietic Stem-Cell Rescue for Refractory and Recurrent Primary CNS and Intraocular Lymphoma: Société Française de Greffe de Moëlle Osseuse-Thérapie Cellulaire
	Carole Soussain, Khê Hoang-Xuan, Luc Taillandier, Emmanuelle Fourme, Sylvain Choquet, Francis Witz, Olivier Casasnovas, Brigitte Dupriez, Bertrand Souleau, Anne-Laure Taksin, Christian Gisselbrecht, Arnaud Jaccard, Antonio Omuro, Marc Sanson, Maud Janvier, Brigitte Kolb, Jean-Marc Zini, and Véronique Leblond
	JCO May 20 2008: 2512–2518. First published on Apr 14 2008; 10.1200/JCO.2007.13.5533. [Abstract] [Full Text] [PDF]
	Higher Doses of Lenalidomide Are Associated With Unacceptable Toxicity Including Life-Threatening Tumor Flare in Patients With Chronic Lymphocytic Leukemia
	Leslie A. Andritsos, Amy J. Johnson, Gerard Lozanski, William Blum, Cheryl Kefauver, Farrukh Awan, Lisa L. Smith, Rosa Lapalombella, Sarah E. May, Chelsey A. Raymond, Da-Sheng Wang, Robert D. Knight, Amy S. Ruppert, Amy Lehman, David Jarjoura, Ching-Shih Chen, and John C. Byrd
	JCO May 20 2008: 2519–2525. First published on Apr 21 2008; 10.1200/JCO.2007.13.9709. [Abstract] [Full Text] [PDF] [Publisher's Note]

Gastrointestinal Cancer
	Prospective Phase II Trial of Neoadjuvant Chemotherapy With Gemcitabine and Cisplatin for Resectable Adenocarcinoma of the Pancreatic Head
	Stefan Heinrich, Bernhard C. Pestalozzi, Markus Schäfer, Achim Weber, Peter Bauerfeind, Alexander Knuth, and Pierre-Alain Clavien
	JCO May 20 2008: 2526–2531. [Abstract] [Full Text] [PDF]
	Adjuvant Chemotherapy for Stage III Colon Cancer: Do Physicians Agree About the Importance of Patient Age and Comorbidity?
	Nancy L. Keating, Mary Beth Landrum, Carrie N. Klabunde, Robert H. Fletcher, Selwyn O. Rogers, William R. Doucette, Diana Tisnado, Steven Clauser, and Katherine L. Kahn
	JCO May 20 2008: 2532–2537. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Assessing 2-Month Clinical Prognosis in Hospitalized Patients With Advanced Solid Tumors
	Anne-Claire Barbot, Pascale Mussault, Pierre Ingrand, and Jean-Marc Tourani
	JCO May 20 2008: 2538–2543. [Abstract] [Full Text] [PDF]
	Pain Predicts Overall Survival in Men With Metastatic Castration-Refractory Prostate Cancer
	Susan Halabi, Nicholas J. Vogelzang, Alice B. Kornblith, San-San Ou, Philip W. Kantoff, Nancy A. Dawson, and Eric J. Small
	JCO May 20 2008: 2544–2549. [Abstract] [Full Text] [PDF]

Aids-Related Cancer
	HIV-Specific Differences in Outcome of Squamous Cell Carcinoma of the Anal Canal: A Multicentric Cohort Study of HIV-Positive Patients Receiving Highly Active Antiretroviral Therapy
	Christoph Oehler-Jänne, Florence Huguet, Sawyna Provencher, Burkhardt Seifert, Laura Negretti, Marc-Oliver Riener, Marta Bonet, Abdelkarim S. Allal, and I. Frank Ciernik
	JCO May 20 2008: 2550–2557. First published on Apr 21 2008; 10.1200/JCO.2007.15.2348. [Abstract] [Full Text] [PDF]

Gynecologic Cancer
	Histologic Results of Para-Aortic Lymphadenectomy in Patients Treated for Stage IB2/II Cervical Cancer With Negative [18F]Fluorodeoxyglucose Positron Emission Tomography Scans in the Para-Aortic Area
	Mathias Boughanim, Sophie Leboulleux, Annie Rey, Chi Tuan Pham, Yaelle Zafrani, Pierre Duvillard, Jean Lumbroso, Christine Haie-Meder, Martin Schlumberger, and Philippe Morice
	JCO May 20 2008: 2558–2561. [Abstract] [Full Text] [PDF]

ASCO SPECIAL ARTICLE
	American Society of Clinical Oncology Statement on Minimum Standards and Exemplary Attributes of Clinical Trial Sites
	Robin Zon, Neal J. Meropol, Robert B. Catalano, and Richard L. Schilsky
	JCO May 20 2008: 2562–2567. First published on Apr 7 2008; 10.1200/JCO.2007.15.6398. [Abstract] [Full Text] [PDF]

BIOLOGY OF NEOPLASIA
	Basal-Like Breast Cancer: A Critical Review
	Emad A. Rakha, Jorge S. Reis-Filho, and Ian O. Ellis
	JCO May 20 2008: 2568–2581. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Bilateral Eardrum Perforation After Long-Term Treatment With Erlotinib

Slow Ming Lee, Tomas Buchler, Theo Joseph, and Cecilia Lai

JCO May 20 2008: 2582–2584. [Full Text] [PDF]

Rituximab-Induced Hepatitis C Virus Reactivation After Spontaneous Remission in Diffuse Large B-Cell Lymphoma

Ching-Yun Hsieh, Hsin-Hui Huang, Chen-Yuan Lin, Lo Woei Chung, Yu-Mine Liao, Li-Yuan Bai, and Chang-Fang Chiu

JCO May 20 2008: 2584–2586. [Full Text] [PDF]

Management of a Presacral Teratoma in an Adult

Susana C. Wishnia, Jennifer E. Rosen, M. Adel Hamid, Susan Haas, and Nilda Moreno-Ruiz

JCO May 20 2008: 2586–2589. [Full Text] [PDF]

CORRESPONDENCE

On Equipoise and Emerging Technologies

Brett E. Lewis

JCO May 20 2008: 2590. First published on Apr 28 2008; 10.1200/JCO.2008.16.5191. [Full Text] [PDF]

Proton Therapy Should Be Tested in Randomized Trials

Fergus R. Macbeth and Michael V. Williams

JCO May 20 2008: 2590-a–2591. First published on Apr 28 2008; 10.1200/JCO.2008.16.5514. [Full Text] [PDF]

A Patient's Perspective on Randomized Clinical Trials for Proton Radiotherapy

James P. Morgan

JCO May 20 2008: 2592. First published on Apr 28 2008; 10.1200/JCO.2008.16.5605. [Full Text] [PDF]

In Reply

Michael Brada, Dirk De Ruysscher, and Madelon Pijls-Johannesma

JCO May 20 2008: 2592-a–2593. First published on Apr 28 2008; 10.1200/JCO.2008.16.5670. [Full Text] [PDF]

In Reply

Michael Goitein and James D. Cox

JCO May 20 2008: 2593–2596. First published on Apr 28 2008; 10.1200/JCO.2008.16.5662. [Full Text] [PDF]

Hormone Receptor, Grade, Human Epidermal Growth Factor Receptor 2, and Topoisomerase II As Predictors of Response to Chemotherapy

Rita S. Mehta

JCO May 20 2008: 2596. [Full Text] [PDF]

In Reply

Kathleen I. Pritchard, Maureen Trudeau, Hans Messersmith, Leela Elavathil, Frances O'Malley, and Bindi Dhesy-Thind

JCO May 20 2008: 2596-a–2597. [Full Text] [PDF]

Hepatic Arterial Infusion: A Treatment at the "End of an Era"?

Derek G. Power and Gregory D. Leonard

JCO May 20 2008: 2597–2598. [Full Text] [PDF]

In Reply

Simone Mocellin

JCO May 20 2008: 2598–2599. [Full Text] [PDF]

Effect of Epoetin on Survival in Patients With Breast Cancer

Giovanni Codacci-Pisanelli, Gian Paolo Spinelli, and Silverio Tomao

JCO May 20 2008: 2599. [Full Text] [PDF]

In Reply

Matti S. Aapro

JCO May 20 2008: 2599-a–2600. [Full Text] [PDF]

Should KRAS Mutations Be Considered an Independent Prognostic Factor in Patients With Advanced Colorectal Cancer Treated With Cetuximab?

Marina Chiara Garassino, Gabriella Farina, Antonio Rossi, Olga Martelli, and Valter Torri

JCO May 20 2008: 2600. [Full Text] [PDF]

In Reply

Astrid Lièvre and Pierre Laurent-Puig

JCO May 20 2008: 2601–2602. [Full Text] [PDF]

Is Single-Agent Chemotherapy Acceptable in Platinum-Sensitive Relapsed Ovarian Cancer?

Rony M. Abou-Jawde and Satinderjit S. Oberoi

JCO May 20 2008: 2602–2603. [Full Text] [PDF]

In Reply

Gabriella Ferrandina, Manuela Ludovisi, Giovanni Scambia, and Sandro Pignata

JCO May 20 2008: 2603. [Full Text] [PDF]

ERRATA

ERRATUM

JCO May 20 2008: 2604. [Full Text] [PDF]

ERRATUM

JCO May 20 2008: 2604-a. [Full Text] [PDF]

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