CELEBRATING 25 YEARS OF JCO

Commentary

High-Dose Methotrexate in Osteosarcoma: Let the Questions Surcease—Time for Final Acceptance

Norman Jaffe and Richard Gorlick

JCO Sep 20 2008: 4365–4366. [Full Text] [PDF] [From JCO 1983]

EDITORIALS

Genomics of Childhood Leukemias: The Virtue of Complexity

Branimir I. Sikic, Robert Tibshirani, and Norman J. Lacayo

JCO Sep 20 2008: 4367–4368. [Full Text] [PDF]

Ectopic Lymph Nodes Within Human Solid Tumors

Domenico Coppola and James J. Mulé

JCO Sep 20 2008: 4369–4370. [Full Text] [PDF]

Osteoporosis in Men With Prostate Cancer: Now for the Fracture Data

Matthew R. Smith

JCO Sep 20 2008: 4371–4372. [Full Text] [PDF]

Raising the Profile of Cancer of Unknown Primary

Karin A. Oien and T.R. Jeffry Evans

JCO Sep 20 2008: 4373–4375. [Full Text] [PDF]

ORIGINAL REPORTS
Pediatric Oncology
	Gene Expression Signatures Predictive of Early Response and Outcome in High-Risk Childhood Acute Lymphoblastic Leukemia: A Children's Oncology Group Study
	Deepa Bhojwani, Huining Kang, Renee X. Menezes, Wenjian Yang, Harland Sather, Naomi P. Moskowitz, Dong-Joon Min, Jeffrey W. Potter, Richard Harvey, Stephen P. Hunger, Nita Seibel, Elizabeth A. Raetz, Rob Pieters, Martin A. Horstmann, Mary V. Relling, Monique L. den Boer, Cheryl L. Willman, and William L. Carroll
	JCO Sep 20 2008: 4376–4384. [Abstract] [Full Text] [PDF] [Publisher's Note]
	Results of the EICESS-92 Study: Two Randomized Trials of Ewing's Sarcoma Treatment—Cyclophosphamide Compared With Ifosfamide in Standard-Risk Patients and Assessment of Benefit of Etoposide Added to Standard Treatment in High-Risk Patients
	Michael Paulussen, Alan W. Craft, Ian Lewis, Allan Hackshaw, Carolyn Douglas, Jürgen Dunst, Andreas Schuck, Winfried Winkelmann, Gabriele Köhler, Christopher Poremba, Andreas Zoubek, Ruth Ladenstein, Henk van den Berg, Andrea Hunold, Anna Cassoni, David Spooner, Robert Grimer, Jeremy Whelan, Anne McTiernan, and Herbert Jürgens
	JCO Sep 20 2008: 4385–4393. [Abstract] [Full Text] [PDF]
	Phase I Study of Weekly Oxaliplatin in Relapsed or Refractory Pediatric Solid Malignancies
	Birgit Geoerger, François Doz, Jean-Claude Gentet, Michele Mayer, Judith Landman-Parker, Fabienne Pichon, Pascal Chastagner, Hervé Rubie, Didier Frappaz, Anne Le Bouil, Sunil Gupta, and Gilles Vassal
	JCO Sep 20 2008: 4394–4400. [Abstract] [Full Text] [PDF]
	Medical Care in Long-Term Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study
	Paul C. Nathan, Mark L. Greenberg, Kirsten K. Ness, Melissa M. Hudson, Ann C. Mertens, Martin C. Mahoney, James G. Gurney, Sarah S. Donaldson, Wendy M. Leisenring, Leslie L. Robison, and Kevin C. Oeffinger
	JCO Sep 20 2008: 4401–4409. [Abstract] [Full Text] [PDF]

Thoracic Oncology
	Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures
	Marie-Caroline Dieu-Nosjean, Martine Antoine, Claire Danel, Didier Heudes, Marie Wislez, Virginie Poulot, Nathalie Rabbe, Ludivine Laurans, Eric Tartour, Luc de Chaisemartin, Serge Lebecque, Wolf-Herman Fridman, and Jacques Cadranel
	JCO Sep 20 2008: 4410–4417. [Abstract] [Full Text] [PDF]
	Induction of Immune Responses and Clinical Efficacy in a Phase II Trial of IDM-2101, a 10-Epitope Cytotoxic T-Lymphocyte Vaccine, in Metastatic Non–Small-Cell Lung Cancer
	Minal Barve, James Bender, Neil Senzer, Casey Cunningham, F. Anthony Greco, David McCune, Ronald Steis, Hung Khong, Donald Richards, Joe Stephenson, Prasanthi Ganesa, Jackie Nemunaitis, Glenn Ishioka, Beena Pappen, Michael Nemunaitis, Michael Morse, Bonnie Mills, Phillip B. Maples, Jeffrey Sherman, and John J. Nemunaitis
	JCO Sep 20 2008: 4418–4425. [Abstract] [Full Text] [PDF]

Cancer Related Complications
	Skeletal Health After Continuation, Withdrawal, or Delay of Alendronate in Men With Prostate Cancer Undergoing Androgen-Deprivation Therapy
	Susan L. Greenspan, Joel B. Nelson, Donald L. Trump, Julie M. Wagner, Megan E. Miller, Subashan Perera, and Neil M. Resnick
	JCO Sep 20 2008: 4426–4434. [Abstract] [Full Text] [PDF]

Unknown Primary Site Cancer
	Gene Expression Profiling to Identify the Histogenetic Origin of Metastatic Adenocarcinomas of Unknown Primary
	Hugo M. Horlings, Ryan K. van Laar, Jan-Martijn Kerst, Helgi H. Helgason, Jelle Wesseling, Jacobus J.M. van der Hoeven, Marc O. Warmoes, Arno Floore, Anke Witteveen, Jaana Lahti-Domenici, Annuska M. Glas, Laura J. Van't Veer, and Daphne de Jong
	JCO Sep 20 2008: 4435–4441. [Abstract] [Full Text] [PDF]
	Molecular Profiling of Carcinoma of Unknown Primary and Correlation With Clinical Evaluation
	Gauri R. Varadhachary, Dmitri Talantov, Martin N. Raber, Christina Meng, Kenneth R. Hess, Tim Jatkoe, Renato Lenzi, David R. Spigel, Yixin Wang, F. Anthony Greco, James L. Abbruzzese, and John D. Hainsworth
	JCO Sep 20 2008: 4442–4448. [Abstract] [Full Text] [PDF]

Breast Cancer
	Tumor Metabolism and Blood Flow Changes by Positron Emission Tomography: Relation to Survival in Patients Treated With Neoadjuvant Chemotherapy for Locally Advanced Breast Cancer
	Lisa K. Dunnwald, Julie R. Gralow, Georgiana K. Ellis, Robert B. Livingston, Hannah M. Linden, Jennifer M. Specht, Robert K. Doot, Thomas J. Lawton, William E. Barlow, Brenda F. Kurland, Erin K. Schubert, and David A. Mankoff
	JCO Sep 20 2008: 4449–4457. First published on Jul 14 2008; 10.1200/JCO.2007.15.4385. [Abstract] [Full Text] [PDF]

Clinical Trials
	Identification of Cancer Care and Protocol Characteristics Associated With Recruitment in Breast Cancer Clinical Trials
	Julie Lemieux, Pamela J. Goodwin, Kathleen I. Pritchard, Karen A. Gelmon, Louise J. Bordeleau, Thierry Duchesne, Stéphanie Camden, and Caroline H. Speers
	JCO Sep 20 2008: 4458–4465. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Causes of Fecal and Urinary Incontinence After Total Mesorectal Excision for Rectal Cancer Based on Cadaveric Surgery: A Study From the Cooperative Clinical Investigators of the Dutch Total Mesorectal Excision Trial
	Christian Wallner, Marilyne M. Lange, Bert A. Bonsing, Cornelis P. Maas, Charles N. Wallace, Noshir F. Dabhoiwala, Harm J. Rutten, Wouter H. Lamers, Marco C. DeRuiter, and Cornelis J.H. van de Velde
	JCO Sep 20 2008: 4466–4472. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Phase II Multicenter Study of Bendamustine Plus Rituximab in Patients With Relapsed Indolent B-Cell and Mantle Cell Non-Hodgkin's Lymphoma
	K. Sue Robinson, Michael E. Williams, Richard H. van der Jagt, Philip Cohen, Jordan A. Herst, Anil Tulpule, Lee S. Schwartzberg, Bernard Lemieux, and Bruce D. Cheson
	JCO Sep 20 2008: 4473–4479. First published on Jul 14 2008; 10.1200/JCO.2008.17.0001. [Abstract] [Full Text] [PDF]

Supportive Care and Quality of Life
	Prospective Relationships of Physical Activity With Quality of Life Among Colorectal Cancer Survivors
	Brigid M. Lynch, Ester Cerin, Neville Owen, Anna L. Hawkes, and Joanne F. Aitken
	JCO Sep 20 2008: 4480–4487. [Abstract] [Full Text] [PDF]
	Randomized Controlled Trial of Collaborative Care Management of Depression Among Low-Income Patients With Cancer
	Kathleen Ell, Bin Xie, Brenda Quon, David I. Quinn, Megan Dwight-Johnson, and Pey-Jiuan Lee
	JCO Sep 20 2008: 4488–4496. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Novel Insights in Chronic Lymphocytic Leukemia: Are We Getting Closer to Understanding the Pathogenesis of the Disease?
	Federico Caligaris-Cappio and Paolo Ghia
	JCO Sep 20 2008: 4497–4503. First published on Jul 28 2008; 10.1200/JCO.2007.15.4393. [Abstract] [Full Text] [PDF]

ART OF ONCOLOGY

Blogging During Terminal Care: Communication, Color Schemes, and Creating a Community

Leon A. Bach

JCO Sep 20 2008: 4504–4506. [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Intracranial Granulocytic Sarcoma After Chemotherapy for Pineal Germinoma and Testicular Cancer

Maria Grazia Passarin, Emanuela Vattemi, Anna Maria Musso, Silvia Romito, Giuseppe Moretto, Claudio Ghimenton, Paolo Iuzzolino, Claudio Doglioni, and Rebecca Pedersini

JCO Sep 20 2008: 4507–4509. [Full Text] [PDF]

Splenic Marginal Zone Lymphoma: Transformation to Diffuse Large B-Cell Lymhoma With Isolated Cerebral Manifestation

Nils H. Thoennissen, Kathy Keyvani, Hans U. Voelker, Janbernd Bremer, Utz Krug, Carsten Müller-Tidow, Peter Koch, Hans K. Müller-Hermelink, and Wolfgang E. Berdel

JCO Sep 20 2008: 4509–4511. [Full Text] [PDF]

Complete Remission of Psoriasis After Autologous Hematopoietic Stem-Cell Transplantation for Multiple Myeloma

Fadi Braiteh, Sharon R. Hymes, Sergio A. Giralt, and Roy Jones

JCO Sep 20 2008: 4511–4513. [Full Text] [PDF]

CORRESPONDENCE

Epithelial Atypia: A Marker Risk of Concomitant or Subsequent Breast Carcinoma?

Isabelle de Mascarel, Gaëtan MacGrogan, Anne Vincent-Salomon, Simone Mathoulin-Pélissier, Véronique Brouste, Brigitte Sigal-Zafrani, Marc Debled, Louis Mauriac, and Christine Tunon de Lara

JCO Sep 20 2008: 4514–4515. [Full Text] [PDF]

In Reply

Amy C. Degnim, Lynn C. Hartmann, Marlene Frost, Carol Reynolds, and Robert A. Vierkant

JCO Sep 20 2008: 4515. [Full Text] [PDF]

Patient Age and Comorbidity Are Major Determinants of Adjuvant Chemotherapy Use for Stage III Colon Cancer in Routine Clinical Practice

Sumitra Ananda, Kathryn M. Field, Suzanne Kosmider, Daniel Compston, Jayesh Desai, Lionel C. Lim, Frances S. Barnett, Ian T. Jones, Iain Skinner, and Peter Gibbs

JCO Sep 20 2008: 4516–4517. [Full Text] [PDF]

In Reply:

Nancy L. Keating and Katherine L. Kahn

JCO Sep 20 2008: 4517–4518. [Full Text] [PDF]

Non-Hodgkin's Lymphoma in Patients With Glioma Treated With Temozolomide

Bart Neyns, Susanna Cordera, Eric Joosens, and Pouratian Nader

JCO Sep 20 2008: 4518–4519. [Full Text] [PDF]

From Bench to Bedside: A Case of Rapid Reversal of Bortezomib-Induced Neuropathic Pain by the TRPM8 Activator, Menthol

Leslie A. Colvin, Peter R.E. Johnson, Rory Mitchell, Susan M. Fleetwood-Walker, and Marie Fallon

JCO Sep 20 2008: 4519–4520. [Full Text] [PDF]

Treatment Considerations for Gallbladder Cancer Should Include Extent of Surgery

Sean P. Cleary, Jensen C.C. Tan, Calvin H.L. Law, and Natalie G. Coburn

JCO Sep 20 2008: 4521–4522. [Full Text] [PDF]

Prediction Model for Adjuvant Radiation Therapy for Gallbladder Cancer: Not Ready to Be Used

Gerardo F. Arroyo and Gaston Lemoine

JCO Sep 20 2008: 4522–4523. [Full Text] [PDF]

Impact of Immediate Postoperative Death on the Estimation of a Survival Benefit From Postoperative Radiation Therapy for Cancer of the Gallbladder

James B. Yu, Daniel Zelterman, Roy H. Decker, and Jonathan P.S. Knisely

JCO Sep 20 2008: 4523. [Full Text] [PDF]

In Reply

Samuel J. Wang, C. David Fuller, Jong-Sung Kim, and Charles R. Thomas, Jr

JCO Sep 20 2008: 4524–4526. [Full Text] [PDF]

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