CELEBRATING 25 YEARS OF JCO

Commentary

Evolution of Breast-Conserving Therapy for Localized Breast Cancer

Stuart J. Schnitt and Jay R. Harris

JCO Mar 20 2008: 1395–1396. [Full Text] [PDF] [From JCO 1983]

EDITORIALS

Interactions Between Treatment and Continuous Covariates: A Step Toward Individualizing Therapy

Patrick Royston and Willi Sauerbrei

JCO Mar 20 2008: 1397–1399. [Full Text] [PDF]

Alternate Statistical Tools and Limitations in Genetic Marker Association Studies in Single-Arm Drug Cancer Trials

Kouros Owzar

JCO Mar 20 2008: 1400–1401. [Full Text] [PDF]

Are Vaccines Making a Comeback in Non–Small-Cell Lung Cancer?

John J. Nemunaitis

JCO Mar 20 2008: 1402–1403. [Full Text] [PDF]

ORIGINAL REPORTS
Breast Cancer
	Chemoendocrine Compared With Endocrine Adjuvant Therapies for Node-Negative Breast Cancer: Predictive Value of Centrally Reviewed Expression of Estrogen and Progesterone Receptors—International Breast Cancer Study Group
	Giuseppe Viale, Meredith M. Regan, Eugenio Maiorano, Mauro G. Mastropasqua, Rastko Golouh, Tiziana Perin, Robert W. Brown, Anikó Kovács, Komala Pillay, Christian Öhlschlegel, Stephen Braye, Piergiovanni Grigolato, Tiziana Rusca, Richard D. Gelber, Monica Castiglione-Gertsch, Karen N. Price, Aron Goldhirsch, Barry A. Gusterson, and Alan S. Coates
	JCO Mar 20 2008: 1404–1410. [Abstract] [Full Text] [PDF]
	Oral Contraceptives, Postmenopausal Hormones, and Risk of Asynchronous Bilateral Breast Cancer: The WECARE Study Group
	Jane C. Figueiredo, Leslie Bernstein, Marinela Capanu, Kathleen E. Malone, Charles F. Lynch, Hoda Anton-Culver, Marilyn Stovall, Lisbeth Bertelsen, Robert W. Haile, and Jonine L. Bernstein
	JCO Mar 20 2008: 1411–1418. First published on Feb 4 2008; 10.1200/JCO.2007.14.3081. [Abstract] [Full Text] [PDF]
	Estrogen Receptor, Progesterone Receptor, HER-2, and Response to Postmastectomy Radiotherapy in High-Risk Breast Cancer: The Danish Breast Cancer Cooperative Group
	Marianne Kyndi, Flemming B. Sørensen, Helle Knudsen, Marie Overgaard, Hanne Melgaard Nielsen, and Jens Overgaard
	JCO Mar 20 2008: 1419–1426. First published on Feb 19 2008; 10.1200/JCO.2007.14.5565. [Abstract] [Full Text] [PDF]

Gastrointestinal Cancer
	Pharmacogenetic Profiling for Cetuximab Plus Irinotecan Therapy in Patients With Refractory Advanced Colorectal Cancer
	Francesco Graziano, Annamaria Ruzzo, Fotios Loupakis, Emanuele Canestrari, Daniele Santini, Vincenzo Catalano, Renato Bisonni, Umberto Torresi, Irene Floriani, Gaia Schiavon, Francesca Andreoni, Paolo Maltese, Eliana Rulli, Bostjan Humar, Alfredo Falcone, Lucio Giustini, Giuseppe Tonini, Andrea Fontana, Gianluca Masi, and Mauro Magnani
	JCO Mar 20 2008: 1427–1434. [Abstract] [Full Text] [PDF]
	Phase III Trial in Metastatic Gastroesophageal Adenocarcinoma with Fluorouracil, Leucovorin Plus Either Oxaliplatin or Cisplatin: A Study of the Arbeitsgemeinschaft Internistische Onkologie
	Salah-Eddin Al-Batran, Joerg Thomas Hartmann, Stephan Probst, Harald Schmalenberg, Stephan Hollerbach, Ralf Hofheinz, Volker Rethwisch, Gernot Seipelt, Nils Homann, Gerhard Wilhelm, Gunter Schuch, Jan Stoehlmacher, Hans Günter Derigs, Susanna Hegewisch-Becker, Johannes Grossmann, Claudia Pauligk, Akin Atmaca, Carsten Bokemeyer, Alexander Knuth, and Elke Jäger
	JCO Mar 20 2008: 1435–1442. [Abstract] [Full Text] [PDF]
	Irinotecan/Fluorouracil Combination in First-Line Therapy of Older and Younger Patients With Metastatic Colorectal Cancer: Combined Analysis of 2,691 Patients in Randomized Controlled Trials
	Gunnar Folprecht, Matthew T. Seymour, Leonard Saltz, Jean-Yves Douillard, Hartmut Hecker, Richard J. Stephens, Timothy S. Maughan, Eric Van Cutsem, Philippe Rougier, Emmanuel Mitry, Ute Schubert, and Claus-Henning Köhne
	JCO Mar 20 2008: 1443–1451. [Abstract] [Full Text] [PDF]

Thoracic Oncology
	Phase II Randomized Controlled Trial of an Epidermal Growth Factor Vaccine in Advanced Non–Small-Cell Lung Cancer
	Elia Neninger Vinageras, Ana de la Torre, Marta Osorio Rodríguez, Mauricio Catalá Ferrer, Idania Bravo, Mario Mendoza del Pino, Daniel Abreu Abreu, Soraida Acosta Brooks, Rolando Rives, Concepción del Castillo Carrillo, Marta González Dueñas, Carmen Viada, Beatriz García Verdecia, Tania Crombet Ramos, Gisela González Marinello, and Agustín Lage Dávila
	JCO Mar 20 2008: 1452–1458. [Abstract] [Full Text] [PDF]
	Prognostic Value of Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography Imaging in Patients With Advanced-Stage Non–Small-Cell Lung Carcinoma
	Jenny K. Hoang, Luke F. Hoagland, R. Edward Coleman, April D. Coan, James E. Herndon, II, and Edward F. Patz, Jr
	JCO Mar 20 2008: 1459–1464. [Abstract] [Full Text] [PDF]
	Phase II Trial of Pemetrexed and Gemcitabine in Chemotherapy-Naïve Malignant Pleural Mesothelioma
	Pasi A. Jänne, George R. Simon, Corey J. Langer, Robert N. Taub, Afshin Dowlati, Panos Fidias, Matthew Monberg, Coleman Obasaju, and Hedy Kindler
	JCO Mar 20 2008: 1465–1471. [Abstract] [Full Text] [PDF]
	Molecular Characteristics of Bronchioloalveolar Carcinoma and Adenocarcinoma, Bronchioloalveolar Carcinoma Subtype, Predict Response to Erlotinib
	Vincent A. Miller, Gregory J. Riely, Maureen F. Zakowski, Allan R. Li, Jyoti D. Patel, Robert T. Heelan, Mark G. Kris, Alan B. Sandler, David P. Carbone, Anne Tsao, Roy S. Herbst, Glenn Heller, Marc Ladanyi, William Pao, and David H. Johnson
	JCO Mar 20 2008: 1472–1478. [Abstract] [Full Text] [PDF]

Ethics
	Ontario Cancer Research Ethics Board: Lessons Learned From Developing a Multicenter Regional Institutional Review Board
	Raphael Saginur, Susan F. Dent, Lisa Schwartz, Ronald Heslegrave, Sid Stacey, and Janet Manzo
	JCO Mar 20 2008: 1479–1482. [Abstract] [Full Text] [PDF]

Hematologic Malignancies
	Analysis of Primary CD30+ Cutaneous Lymphoproliferative Disease and Survival From the Surveillance, Epidemiology, and End Results Database
	James B. Yu, Rachel C. Blitzblau, Roy H. Decker, Douglas M. Housman, and Lynn D. Wilson
	JCO Mar 20 2008: 1483–1488. [Abstract] [Full Text] [PDF] [Publisher's Note]

Other Malignancies
	Improved Staging of Patients With Carcinoid and Islet Cell Tumors With 18F-Dihydroxy-Phenyl-Alanine and 11C-5-Hydroxy-Tryptophan Positron Emission Tomography
	Klaas P. Koopmans, Oliver C. Neels, Ido P. Kema, Philip H. Elsinga, Wim J. Sluiter, Koen Vanghillewe, Adrienne H. Brouwers, Pieter L. Jager, and Elisabeth G.E. de Vries
	JCO Mar 20 2008: 1489–1495. [Abstract] [Full Text] [PDF]

Pediatric Oncology
	Prognostic Factors for Leukemic Induction Failure in Children With Acute Lymphoblastic Leukemia and Outcome After Salvage Therapy: The FRALLE 93 Study
	Caroline Oudot, Marie-Françoise Auclerc, Vincent Levy, Raphaël Porcher, Christophe Piguet, Yves Perel, Virginie Gandemer, Marianne Debre, Christiane Vermylen, Brigitte Pautard, Claire Berger, Claudine Schmitt, Thierry Leblanc, Jean-Michel Cayuela, Gérard Socie, Gérard Michel, Guy Leverger, and André Baruchel
	JCO Mar 20 2008: 1496–1503. [Abstract] [Full Text] [PDF]
	Localized Infant Neuroblastomas Often Show Spontaneous Regression: Results of the Prospective Trials NB95-S and NB97
	Barbara Hero, Thorsten Simon, Ruediger Spitz, Karen Ernestus, Astrid K. Gnekow, Hans-Guenther Scheel-Walter, Dirk Schwabe, Freimut H. Schilling, Gabriele Benz-Bohm, and Frank Berthold
	JCO Mar 20 2008: 1504–1510. [Abstract] [Full Text] [PDF]

Clinical Trials
	Analysis of Phase II Studies on Targeted Agents and Subsequent Phase III Trials: What Are the Predictors for Success?
	John K. Chan, Stefanie M. Ueda, Valerie E. Sugiyama, Christopher D. Stave, Jacob Y. Shin, Bradley J. Monk, Branimir I. Sikic, Kathryn Osann, and Daniel S. Kapp
	JCO Mar 20 2008: 1511–1518. First published on Feb 19 2008; 10.1200/JCO.2007.14.8874. [Abstract] [Full Text] [PDF]

Treatment-Related Complications
	Prospective Oral Mucositis Audit: Oral Mucositis in Patients Receiving High-Dose Melphalan or BEAM Conditioning Chemotherapy—European Blood and Marrow Transplantation Mucositis Advisory Group
	Nicole Blijlevens, Matthias Schwenkglenks, Pamela Bacon, Alessandra D'Addio, Hermann Einsele, Johan Maertens, Dietger Niederwieser, Werner Rabitsch, Ann Roosaar, Tapani Ruutu, Harry Schouten, Rebecca Stone, Samuel Vokurka, Barry Quinn, and Shaun McCann
	JCO Mar 20 2008: 1519–1525. First published on Feb 11 2008; 10.1200/JCO.2007.13.6028. [Abstract] [Full Text] [PDF]

Genitourinary Cancer
	External Validation of a Biomarker-Based Preoperative Nomogram Predicts Biochemical Recurrence After Radical Prostatectomy
	Shahrokh F. Shariat, Jochen Walz, Claus G. Roehrborn, Alexandre R. Zlotta, Paul Perrotte, Nazareno Suardi, Fred Saad, and Pierre I. Karakiewicz
	JCO Mar 20 2008: 1526–1531. [Abstract] [Full Text] [PDF]
	Randomization Reveals Unexpected Acute Leukemias in Southwest Oncology Group Prostate Cancer Trial
	Thomas W. Flaig, Catherine M. Tangen, Maha H.A. Hussain, Walter M. Stadler, Derek Raghavan, E. David Crawford, and L. Michael Glodé
	JCO Mar 20 2008: 1532–1536. [Abstract] [Full Text] [PDF]

Prevention
	Psychological and Clinical Factors Implicated in Decision Making About a Trial of Low-Dose Tamoxifen in Hormone Replacement Therapy Users
	Gabriella Rondanina, Matteo Puntoni, Gianluca Severi, Clara Varricchio, Anna Zunino, Irene Feroce, Bernardo Bonanni, and Andrea Decensi
	JCO Mar 20 2008: 1537–1543. [Abstract] [Full Text] [PDF]

REVIEW ARTICLE
	Lenalidomide for the Treatment of B-Cell Malignancies
	Asher A. Chanan-Khan and Bruce D. Cheson
	JCO Mar 20 2008: 1544–1552. First published on Feb 19 2008; 10.1200/JCO.2007.14.5367. [Abstract] [Full Text] [PDF]

DIAGNOSIS IN ONCOLOGY

Intravascular Large B-Cell Lymphoma With Acute Abdomen As a Presenting Symptom in a Patient With Systemic Lupus Erythematosus

Wataru Ishii, Satoshi Ito, Yuya Kondo, Hiroto Tsuboi, Mizuko Mamura, Daisuke Goto, Isao Matsumoto, Akito Tsutsumi, Takayuki Sumida, Yasushi Okoshi, Yuichi Hasegawa, Hiroshi Kojima, Shingo Sakashita, Kumi Aita, and Masayuki Noguchi

JCO Mar 20 2008: 1553–1555. [Full Text] [PDF]

Mantle-Cell Lymphoma (Multiple Lymphomatous Polyposis) of the Entire GI Tract

Spyros Michopoulos, Kalliopi Petraki, Charis Matsouka, Efstathios Kastritis, Heleni Chrysanthopoulou, and Meletios Athanasios Dimopoulos

JCO Mar 20 2008: 1555–1557. [Full Text] [PDF]

Multiple Myeloma With Testicular Involvement

Yu Yan Hwang, Chor-Sang Chim, and Tony W.H. Shek

JCO Mar 20 2008: 1558–1559. [Full Text] [PDF]

ART OF ONCOLOGY

Isn’t There Someone to Blame?

Alan B. Astrow

JCO Mar 20 2008: 1560–1561. [Full Text] [PDF]

CORRESPONDENCE

Effects of Chemoradiation on Tumor-Host Interactions: The Immunologic Side

Silvia C. Formenti and Sandra Demaria

JCO Mar 20 2008: 1562–1563. [Full Text] [PDF]

In Reply

Rob Glynne-Jones and Peter Hoskin

JCO Mar 20 2008: 1563. [Full Text] [PDF]

Opioid-Induced Hyperalgesia May Be More Frequent Than Previously Thought

Zbigniew Zylicz and Robert Twycross

JCO Mar 20 2008: 1564. [Full Text] [PDF]

In Reply

Mellar P. Davis and Martin Angst

JCO Mar 20 2008: 1565. [Full Text] [PDF]

Multitargeting Ovarian Epithelial Cancer: Adding the Old to the New

David H. Garfield

JCO Mar 20 2008: 1565-a–1566. [Full Text] [PDF]

Humors of Tumors: Potential for Interaction Between Cancer Type and Treating Oncologist's Personality?

Craig P. Carden and Ian R. Judson

JCO Mar 20 2008: 1566–1567. [Full Text] [PDF]

Treatment of Breast Cancer With Trastuzumab During Pregnancy

Shubham Pant, Mark B. Landon, Michael Blumenfeld, William Farrar, and Charles L. Shapiro

JCO Mar 20 2008: 1567–1569. [Full Text] [PDF]

Transient Sunitinib-Induced Coma in a Patient With Fibromyxoid Sarcoma

Laurent Arnaud, Noël E.C. Schartz, Guilhem Bousquet, Farid Sarandi, Olivier Verola, Isabelle Madelaine, Delphine Kerob, and Céleste Lebbe

JCO Mar 20 2008: 1569–1571. [Full Text] [PDF] [Publisher's Note]

Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: 30% Versus 10% Cutoff for Immunohistochemistry

Omar Hameed, David Chhieng, and Amy L. Adams

JCO Mar 20 2008: 1571. [Full Text] [PDF]

ERRATA

ERRATUM

JCO Mar 20 2008: 1572. [Full Text] [PDF]

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